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Anti-PARP Monoclonal Antibody (3B755)
(Synonyms: PPOL, PARP-1, PARP1, PARP, pADPRT-1, ADPRT1, ADPRT) Copy Product Info
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Synonyms: PPOL, PARP-1, PARP1, PARP, pADPRT-1, ADPRT1, ADPRT
Catalog No. TMAT-0783 Copy Product Info
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Anti-PARP Monoclonal Antibody (3B755) is a Mouse antibody targeting PARP. Anti-PARP Monoclonal Antibody (3B755) can be used in WB,FCM.
Anti-PARP Monoclonal Antibody
(3B755)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-PARP Monoclonal Antibody (3B755) is a Mouse antibody targeting PARP. Anti-PARP Monoclonal Antibody (3B755) can be used in WB,FCM. |
| Synonyms | PPOL, PARP-1, PARP1, PARP, pADPRT-1, ADPRT1, ADPRT |
| Ig Type | IgG1 |
| Clone | 3B755 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. |
| Conjucates | Unconjugated |
| Immunogen | Synthetic peptide of human PARP, conjugated to KLH. |
| Antigen Species | Human |
| Gene Name | PARP1 |
| Gene ID | |
| Protein Name | Poly [ADP-ribose] polymerase 1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 117 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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