T27691 |
JNJ-DGAT2-A
|
1962931-71-0
|
98%
|
|
JNJ-DGAT2-A, a specific inhibitor of DGAT2(IC50 = 0.14 μM), can be used in studies about the synthesis of triglycerides.
|
TN3257 |
7beta-Methoxyrosmanol
|
24703-38-6
|
98%
|
|
7beta-Methoxyrosmanol inhibited acyl CoA:diacylglycerol acyltransferase (DGAT)1 activity, with the IC50 values ranging from 39.5 ± 0.6 to 144.2 ± 3.1 μM.
|
T6937 |
PF-04620110
|
1109276-89-2
|
98%
|
|
PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.
|
T10119 |
3-O-Methyltolcapone
|
134612-80-9
|
98%
|
|
3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor. Tolcapone crosses the blood-brain barrier and can be used for tre...
|
T13181 |
Tolcapone D7
|
T13181
|
98%
|
|
Tolcapone D7 is a deuterium-labeled Tolcapone. Tolcapone is a selective and orally active inhibitor of COMT.
|
T11491 |
GSK2973980A
|
2219321-25-0
|
98%
|
|
GSK2973980A is a selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitor (IC50: 3 nM).
|
T14375 |
AZD3988
|
892489-52-0
|
98%
|
|
AZD3988 is an inhibitor of diacylglycerol acyl transferase-1 (DGAT-1). For human, rat, mouse, the IC50s values are 6, 5, 11 nM , respectively.
|
T11396 |
GGTI-2418
|
501010-06-6
|
98%
|
|
GGTI-2418 inhibits GGTase I and FTase activities with IC50s of 9.5 nM and 53 μM, respectively. GGTI-2418 also increases p27(Kip1) and induces significant regress...
|
T11016 |
DGAT-1 inhibitor 2
|
942999-61-3
|
98%
|
|
DGAT-1 inhibitor 2 is an effective DGAT-1 inhibitor; anti-obesity drug. Objective: DGAT-1 acyl-CoA: diacylglycerol acyltransferase 1 (DGAT1) is one of two known ...
|
T2678 |
LB42708
|
226929-39-1
|
98%
|
|
LB42708 is an orally active farnesyltransferase (FTase) inhibitor (IC50: 0.8/1.2/2.0 nM toward H/N/K-ras).
|
T12426 |
PF-06424439
|
1469284-78-3
|
98%
|
|
PF-06424439 is an oral and selective inhibitor of imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) (IC50 of 14 nM).
|
T10118 |
3-O-Methyltolcapone D7
|
T10118
|
98%
|
|
3-O-Methyltolcapone D7 (Ro 40-7591 D7) is a deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a poten...
|
T11282 |
FGTI-2734
|
1247018-19-4
|
98%
|
|
FGTI-2734 can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors. FGTI-2734...
|
T23109 |
3,5-Dinitrocatechol
|
7659-29-2
|
98%
|
|
inhibitor of catechol-O-methyl-transferase
|
T17102 |
Tipifarnib (S enantiomer)
|
192185-71-0
|
98%
|
|
Tipifarnib S enantiomer is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase inhibitor (IC50: 0.6 nM).
|
T38050 |
CP-609754
|
1190094-64-4
|
98%
|
|
CP-609754 (LNK-754) is a potent and reversible farnesyltransferase inhibitor with potential anticancer activity.The IC50 for inhibiting farnesylation of recombin...
|
T24030 |
Entacapone acid
|
160391-70-8
|
98%
|
|
Entacapone is a selective and reversible catechol-O-methyltransferase inhibitor.
|
T15109 |
DGAT1-IN-1
|
1449779-49-0
|
98%
|
|
DGAT1-IN-1 is a potent inhibitor of DGAT1 (IC50: < 10 nM in cell lysate from Hep3B cells overexpressing human DGAT1).
|
T1455 |
Nialamide
|
51-12-7
|
93.91%
|
|
Nialamide is an MAO inhibitor that is used as an antidepressive agent.
|
T6365 |
A 922500
|
959122-11-3
|
97.34%
|
|
A922500 is an inhibitor for human and mouse DGAT-1 with IC50 of 7 nM and 24 nM, respectively, good selectivity over related acyltransferases, hERG, and a panel o...
|