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Transferase

A transferase is any one of a class of enzymes that catalyse the transfer of specific functional groups (e.g. a methyl or glycosyl group) from one molecule (called the donor) to another (called the acceptor). They are involved in hundreds of different biochemical pathways throughout biology, and are integral to some of life's most important processes.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T11827 Pradigastat 956136-95-1 95.21%
Pradigastat
Pradigastat (LCQ-908) is an orally active, potent and selective diacylglycerol acyltransferase 1 (DGAT1) inhibitor for the treatment of constipation, which may b...
T9551 P-3FAX-Neu5Ac 117405-58-0 98%
P-3FAX-Neu5Ac
P-3FAX-Neu5Ac is a sialic acid analog and a sialyltransferase inhibitor.
T10118 3-O-Methyltolcapone D7 T10118 98%
3-O-Methyltolcapone D7
3-O-Methyltolcapone D7 (Ro 40-7591 D7) is a deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a poten...
T11491 GSK2973980A 2219321-25-0 98%
GSK2973980A
GSK2973980A is a selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitor (IC50: 3 nM).
T10119 3-O-Methyltolcapone 134612-80-9 98%
3-O-Methyltolcapone
3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor. Tolcapone crosses the blood-brain barrier and can be used for tre...
T13181 Tolcapone D7 T13181 98%
Tolcapone D7
Tolcapone D7 is a deuterium-labeled Tolcapone. Tolcapone is a selective and orally active inhibitor of COMT.
T12426 PF-06424439 1469284-78-3 98%
PF-06424439
PF-06424439 is an oral and selective inhibitor of imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) (IC50 of 14 nM).
T11396 GGTI-2418 501010-06-6 98%
GGTI-2418
GGTI-2418 is a highly potent, competitive, and selective inhibitor of geranylgeranyltransferase I (GGTase I), showing inhibitory activities with IC50 values of 9...
TN3257 7beta-Methoxyrosmanol 24703-38-6 98%
7beta-Methoxyrosmanol
7beta-Methoxyrosmanol inhibited acyl CoA:diacylglycerol acyltransferase (DGAT)1 activity, with the IC50 values ranging from 39.5 ± 0.6 to 144.2 ± 3.1 μM.
T14375 AZD3988 892489-52-0 98%
AZD3988
AZD3988 is an inhibitor of diacylglycerol acyl transferase-1 (DGAT-1). For human, rat, mouse, the IC50s values are 6, 5, 11 nM , respectively.
T40542 Sinbaglustat 441061-33-2 99.93%
Sinbaglustat
Sinbaglustat (OGT2378) (OGT2378) is a dual inhibitor of glucose ceramide synthetase (GCS) and non-lysosomal glucose ceramidase (GBA2).Sinbaglustat is an orally a...
TN2437 Serotonin 50-67-9 99.92%
Serotonin
Serotonin (5-hydroxytryptamine) is a natural product from animals
T0419 Testosterone propionate 57-85-2 99.92%
Testosterone propionate
Testosterone Propionate is a short acting oil-based injectable formulation of testosterone. Testosterone inhibits gonadotropin secretion from the pituitary gland...
T23109 3,5-Dinitrocatechol 7659-29-2 99.88%
3,5-Dinitrocatechol
OR-486 is an inhibitor of catechol-O-methyl-transferase(COMT) and can be used to prepare the molybdenum (VI)- 3,5-Dinitrocatechol complex.
T2209 Serotonin hydrochloride 153-98-0 99.86%
Serotonin hydrochloride
Serotonin hydrochloride (Serotonin HCl) is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol O-methyltransferase (COMT...
T0379 Risedronic Acid 105462-24-6 99.85%
Risedronic Acid
Risedronic Acid (Risedronate), a pyridinyl biphosphonate, can inhibit osteoclast-mediated bone resorption.
T6937 PF-04620110 1109276-89-2 99.82%
PF-04620110
PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.
T24088 GGTI-2133 191102-79-1 99.80%
GGTI-2133
GGTI-2133 is a potent mimetic peptidyl geranylgeranyltransferase type I inhibitor (GGTase I) with an IC50 value of 38 nM.GGTI-2133 inhibits the invasion of infla...
T12425 PF-06424439 methanesulfonate 1469284-79-4 99.79%
PF-06424439 methanesulfonate
PF-06424439 methanesulfonate, an orally administered, potent, and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14...
T11599 Ibiglustat (L-Malic acid) 1629063-78-0 99.79%
Ibiglustat (L-Malic acid)
Ibiglustat (L-Malic acid) (Ibiglustat L-Malic acid) is a selective, brain-penetrant, and allosteric inhibitor of glucosylceramide synthase. Ibiglustat (L-Malic a...
Pradigastat
T11827
Pradigastat (LCQ-908) is an orally active, potent and selective diacylglycerol acyltransferase 1 (DGAT1) inhibitor for the treatment of constipation, which may b...
P-3FAX-Neu5Ac
T9551
P-3FAX-Neu5Ac is a sialic acid analog and a sialyltransferase inhibitor.
3-O-Methyltolcapone D7
T10118
3-O-Methyltolcapone D7 (Ro 40-7591 D7) is a deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a poten...
GSK2973980A
T11491
GSK2973980A is a selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitor (IC50: 3 nM).
3-O-Methyltolcapone
T10119
3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor. Tolcapone crosses the blood-brain barrier and can be used for tre...
Tolcapone D7
T13181
Tolcapone D7 is a deuterium-labeled Tolcapone. Tolcapone is a selective and orally active inhibitor of COMT.
PF-06424439
T12426
PF-06424439 is an oral and selective inhibitor of imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) (IC50 of 14 nM).
GGTI-2418
T11396
GGTI-2418 is a highly potent, competitive, and selective inhibitor of geranylgeranyltransferase I (GGTase I), showing inhibitory activities with IC50 values of 9...
7beta-Methoxyrosmanol
TN3257
7beta-Methoxyrosmanol inhibited acyl CoA:diacylglycerol acyltransferase (DGAT)1 activity, with the IC50 values ranging from 39.5 ± 0.6 to 144.2 ± 3.1 μM.
AZD3988
T14375
AZD3988 is an inhibitor of diacylglycerol acyl transferase-1 (DGAT-1). For human, rat, mouse, the IC50s values are 6, 5, 11 nM , respectively.
Sinbaglustat
T40542
Sinbaglustat (OGT2378) (OGT2378) is a dual inhibitor of glucose ceramide synthetase (GCS) and non-lysosomal glucose ceramidase (GBA2).Sinbaglustat is an orally a...
Serotonin
TN2437
Serotonin (5-hydroxytryptamine) is a natural product from animals
Testosterone propionate
T0419
Testosterone Propionate is a short acting oil-based injectable formulation of testosterone. Testosterone inhibits gonadotropin secretion from the pituitary gland...
3,5-Dinitrocatechol
T23109
OR-486 is an inhibitor of catechol-O-methyl-transferase(COMT) and can be used to prepare the molybdenum (VI)- 3,5-Dinitrocatechol complex.
Serotonin hydrochloride
T2209
Serotonin hydrochloride (Serotonin HCl) is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol O-methyltransferase (COMT...
Risedronic Acid
T0379
Risedronic Acid (Risedronate), a pyridinyl biphosphonate, can inhibit osteoclast-mediated bone resorption.
PF-04620110
T6937
PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.
GGTI-2133
T24088
GGTI-2133 is a potent mimetic peptidyl geranylgeranyltransferase type I inhibitor (GGTase I) with an IC50 value of 38 nM.GGTI-2133 inhibits the invasion of infla...
PF-06424439 methanesulfonate
T12425
PF-06424439 methanesulfonate, an orally administered, potent, and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14...
Ibiglustat (L-Malic acid)
T11599
Ibiglustat (L-Malic acid) (Ibiglustat L-Malic acid) is a selective, brain-penetrant, and allosteric inhibitor of glucosylceramide synthase. Ibiglustat (L-Malic a...
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TargetMol