T11016 |
DGAT-1 inhibitor 2
|
942999-61-3
|
98%
|
|
DGAT-1 inhibitor 2 is an effective DGAT-1 inhibitor; anti-obesity drug. Objective: DGAT-1 acyl-CoA: diacylglycerol acyltransferase 1 (DGAT1) is one of two known ...
|
T40542 |
Sinbaglustat
|
441061-33-2
|
98%
|
|
Sinbaglustat (OGT2378) is a dual inhibitor of glucose ceramide synthetase (GCS) and non-lysosomal glucose ceramidase (GBA2).Sinbaglustat is an orally administere...
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T24088 |
GGTI-2133
|
191102-79-1
|
98%
|
|
GGTI-2133 is a potent mimetic peptidyl geranylgeranyltransferase type I inhibitor (GGTase I) with an IC50 value of 38 nM.GGTI-2133 inhibits the invasion of infla...
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T9551 |
P-3FAX-Neu5Ac
|
117405-58-0
|
98%
|
|
P-3FAX-Neu5Ac is a sialic acid analog and a sialyltransferase inhibitor.
|
T10118 |
3-O-Methyltolcapone D7
|
T10118
|
98%
|
|
3-O-Methyltolcapone D7 (Ro 40-7591 D7) is a deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a poten...
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T11491 |
GSK2973980A
|
2219321-25-0
|
98%
|
|
GSK2973980A is a selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitor (IC50: 3 nM).
|
T10119 |
3-O-Methyltolcapone
|
134612-80-9
|
98%
|
|
3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor. Tolcapone crosses the blood-brain barrier and can be used for tre...
|
T13181 |
Tolcapone D7
|
T13181
|
98%
|
|
Tolcapone D7 is a deuterium-labeled Tolcapone. Tolcapone is a selective and orally active inhibitor of COMT.
|
T12426 |
PF-06424439
|
1469284-78-3
|
98%
|
|
PF-06424439 is an oral and selective inhibitor of imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) (IC50 of 14 nM).
|
T11396 |
GGTI-2418
|
501010-06-6
|
98%
|
|
GGTI-2418 inhibits GGTase I and FTase activities with IC50s of 9.5 nM and 53 μM, respectively. GGTI-2418 also increases p27(Kip1) and induces significant regress...
|
TN3257 |
7beta-Methoxyrosmanol
|
24703-38-6
|
98%
|
|
7beta-Methoxyrosmanol inhibited acyl CoA:diacylglycerol acyltransferase (DGAT)1 activity, with the IC50 values ranging from 39.5 ± 0.6 to 144.2 ± 3.1 μM.
|
T6937 |
PF-04620110
|
1109276-89-2
|
98%
|
|
PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.
|
T14375 |
AZD3988
|
892489-52-0
|
98%
|
|
AZD3988 is an inhibitor of diacylglycerol acyl transferase-1 (DGAT-1). For human, rat, mouse, the IC50s values are 6, 5, 11 nM , respectively.
|
T0419 |
Testosterone propionate
|
57-85-2
|
98%
|
|
Testosterone Propionate is a short acting oil-based injectable formulation of testosterone. Testosterone inhibits gonadotropin secretion from the pituitary gland...
|
T23109 |
3,5-Dinitrocatechol
|
7659-29-2
|
98%
|
|
inhibitor of catechol-O-methyl-transferase
|
T2209 |
Serotonin hydrochloride
|
153-98-0
|
98%
|
|
Serotonin hydrochloride is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol O-methyltransferase (COMT) inhibitor(Ki=4...
|
T0379 |
Risedronic Acid
|
105462-24-6
|
98%
|
|
Risedronic acid (Risedronate ), a pyridinyl biphosphonate, can inhibit osteoclast-mediated bone resorption.
|
TN2437 |
Serotonin
|
50-67-9
|
98%
|
|
5-hydroxytryptamine is a natural product from animals
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T12425 |
PF-06424439 methanesulfonate
|
1469284-79-4
|
98%
|
|
PF-06424439 methanesulfonate is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor(IC50 of 14 nM)[1]. PF-06424439 m...
|
T11599 |
Ibiglustat (L-Malic acid)
|
1629063-78-0
|
98%
|
|
Ibiglustat (L-Malic acid) is a selective, brain-penetrant, and allosteric inhibitor of glucosylceramide synthase. Ibiglustat (L-Malic acid) can be used in studie...
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