canine

Motilin canine, a 22-amino acid peptide, functions as a robust gastrointestinal smooth muscle contraction agonist.

Naftopidil (KT-611) (INN, marketed under the brand name Flivas), an antihypertensive medicine, is used as a selective α1-adrenergic receptor antagonist or α-blocker.

NS3623 is an activator of human ether-a-go-go-related gene (hERG) potassium channels with a dual mode of action, also acting as an inhibitor of hERG1 channels. It activates the IKr and Ito currents and exhibits an antiarrhythmic effect.

Naftopidil dihydrochloride (KT-611 2HCl) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.

RHC 80267 (U-57908) is a selective inhibitor of DAGL, with an IC50 of 4 μM in canine platelets.

Naftopidil hydrochloride (BM-15275 hydrochloride) is a selective alpha1-adrenoceptor antagonist with Ki of 3.7 nM, 20 nM and 1.2 nM for the cloned human α1a-adrenoceptor, α1b-adrenoceptor and α1d-adrenoceptor, respectively. Naftopidil hydrochloride has antiproliferative effects.

Anti-Human/Monkey/Canine IL-17A Antibody (Mab7) is a monoclonal inhibitory antibody targeting human, monkey, and canine IL-17A, applicable to inflammation-related research.

Peptide YY (13-36) (canine, mouse, porcine, rat) is a Y2 receptor subtype agonist [1].

GRP (14-27) (human, porcine, canine) serves as a ligand for bombesin receptors, with specific binding inhibited by GTP and GDP, but unaffected by GMP [1].

Anti-Canine PD-L1/B7-H1 Antibody (JC071) is an IgG1, κ antibody inhibitor derived from mice, targeting canine PD-L1/B7-H1.

Anti-Canine CD34 Antibody (1H6) is an IgG1, κ antibody inhibitor derived from mice and targets canine CD34.

Anti-Human/Mouse/Rat/Monkey/Canine/Rabbit IL-1b Antibody (AB7) is an inhibitory antibody that targets IL-1β in human, mouse, rat, monkey, canine, and rabbit, suitable for inflammation-related research.

Anti-Human/Mouse/Rat/Canine/Swine PSMA Antibody (3F11) is an antibody targeting Human/Mouse/Rat/Canine/Swine PSMA and can be used for oncology research.

Anti-Human/Canine HER2 (domain III) Antibody (H2Mab-19) is an antibody targeting Human/Canine HER2 and can be used for oncology research.

Canine IgG Kappa , Isotype Control can be used as an isotype control for canine IgG Kappa antibodies.

Anti-Mouse/Human/Rat/Monkey/Hamster/Canine/Bovine TGF-β Antibody (1D11.16.8) is an IgG antibody inhibitor targeting TGF-β in multiple species including mouse, human, rabbit, monkey, hamster, dog, and cow. For information on the isotype control, refer to Mouse IgG1 kappa, Isotype Control.

Secretin is an endocrine hormone that stimulates the secretion of bicarbonate-rich pancreatic fluids. Canine secretin can regulates gastric chief cell function and paracellular permeability in canine gastric monolayers by a Src kinase-dependent pathway.

Canine KP-10 is a potent kisspeptin that induces a significant gonadotropin and estradiol response in female dogs during estrus.

Secretin, canine TFA, is an endocrine hormone that stimulates the secretion of pancreatic fluid rich in bicarbonate. Additionally, Secretin, canine TFA, can regulate the primary cell functions and paracellular permeability of gastric monolayer cells through an Src kinase-dependent pathway.

Canine Serum Albumin is a plasma protein derived from dogs. This multifunctional protein has an exceptional ligand-binding capacity, making it a transport molecule for various metabolites, drugs, nutrients, metals, and other molecules.

CanineFactor Xa is derived from purified Canine Factor X through activation by Russell's Viper Venom, after which the venom is removed.

Orexin B, canine is a polypeptide molecule with the sequence RPGPPGLQGRLQRLLQASGNHAAGILTM-NH2.

Type I collagen (from canine skin) is a collagen protein capable of stimulating an animal's immune system to produce antibodies specific to this collagen. Additionally, collagen serves as a hydrolytic substrate for matrix metalloproteinases (MMP).

Elobixibat (A 3309) is an inhibitor of the ileal bile acid transporter (IC50: 0.13 nM, 0.53 nM, and 5.8 nM for mouse, human, and canine IBAT). Elobixibat can be used in studies about chronic idiopathic constipation.