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Search Result

Search Results for "ppi"

Libraries

PPI Inhibitor Library Cyclic Peptide Library Macrocyclic Compound Library
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Compounds

Cat No. Product Name
T28441 PPI-1019 Apan Beta Amyloid
PPI-1019 是一种 APP( β -淀粉状蛋白 A4 )抑制剂，可用于治疗神经系统疾病和研究阿尔茨海默病（AD）。
T69258 PPI-2458
PPI-2458 is a synthetic derivative of fumagillin with antineoplastic and cytotoxic properties. PPI-2458 irreversibly inh...
T10217L Abarelix 阿巴瑞克,R3827,PPI 149 GNRH Receptor
Abarelix 是一种促性腺激素释放激素 (GnRH) 拮抗剂，用于前列腺癌研究。
T72785 PRMT5:MEP50 PPI
PRMT5:MEP50 PPI 是一种新型的 PRMT5:MEP50 蛋白-蛋白相互作用 (PRMT5:MEP50 PPI) 抑制剂，其具有抗肿瘤活性和肺癌和前列腺癌细胞的抗增殖活性。
T10217 Abarelix Acetate (183552-38-7 free base) PPI 149 Acetate,Abarelix Acetate Others
Abarelix (PPI 149; R 3827) Acetate is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate canc...
T16421 P-MPPI hydrochloride 5-HT Receptor
p-MPPI hydrochloride 是一种选择性的，具有高亲和力的5-HT1A 受体拮抗剂，能穿过血脑屏障，具有抗抑郁和抗焦虑样作用。
T8873 Bractoppin Others , DNA/RNA Synthesis
Bractoppin 是一种BRCA1 (t)BRCT domain 识别磷酸肽的选择性抑制剂，IC50为 74 nM。它优先抑制 BRCA1 -tBRCT 依赖的 DNA 损伤。它减少 BRCA1 对 DNA 断裂片段的招募，进而抑制损伤...
T22135 PPIase-Parvulin Inhibitor Others
PPIase-Parvulin Inhibitor 是一种抑制剂，可以抑制PPlase Pin1 和Pin4的细胞渗透。
T24652 Poloppin
Poloppin is a protein-protein interactions modulator of the mitotic polo-like kinases that acts by targeting mutant KRAS...
T37893 3-MPPI
TN6340 Philippin A
T22747 DPPI 1c hydrochloride Others
DPPI 1c hydrochloride is an inhibitor of dipeptidyl peptidase IV (IC50 = 104 nM) that shows selectivity over enzymes wit...
TN1646 Flemiphilippinin A Others
Flemiphilippin A has antioxidant activity, it shows DPPH radical scavenging activity with effective half maximal concent...
T4647 M2I-1 M2I 1 Others
M2I-1 是Mad2抑制剂，靶向的 Mad2 与 Cdc20 的结合，该结合是纺锤体装配检查点内必不可少的蛋白-蛋白相互作用。
T6889 MI-136 Androgen Receptor , Epigenetic Reader Domain , Apoptosis
MI136 是 menin-MLL(PPI) 蛋白互作的抑制剂，其 IC50值为31 nM，Kd 值为23.6 nM。它可抑制 DHT 诱导的雄激素受体 (AR) 靶基因的表达，有用于去势抵抗性肿瘤的潜能。
T8784 IGS-1.76 Others
IGS-1.76 exhibits pronounced affinity towards hNCS-1 and effectively modulates the interaction between hNCS-1 and Ric8a....
T7387 Ceftaroline fosamil 头孢罗林酯,PPI0903,TAK-599 Antibiotic , Antibacterial
Ceftaroline fosamil 是一种头孢菌素衍生物，是抗甲氧西林金黄色葡萄球菌 (MRSA) T-91825 的 N-膦酰基前药，可研究 MRSA 感染。
T26859 BMS-8 PD-1/PD-L1
BMS-8 抑制PD-1/PD-L1相互作用(IC50:7.2 μM)。它能够直接与 PD-L1 结合，促使形成 PD-L1 同源二聚体，进而阻断 PD-L1 与 PD-1 的相互作用。
T9039 HIV-1 Nef-IN-1 HIV Protease
HIV-1 Nef-IN-1 是 HIV-1 Nef 蛋白的抑制剂。 它有效地竞争 Nef-SH3Hck 相互作用，Kd 值为 6.7 μM。
T13018 SU3327 JNK
SU3327 是具有底物竞争性的 JNK 选择性抑制剂，IC50为 0.7 μM。它还抑制 JNK 和 JIP 之间的蛋白相互作用，IC50值为 239 nM。
PPI-1019
T28441
synonym: Apan
Target:
PPI-2458
T69258
synonym:
Target:
Abarelix
T10217L
synonym: 阿巴瑞克,R3827,PPI 149
Target:
PRMT5:MEP50 PPI
T72785
synonym:
Target:
Abarelix Acetate (183552-38-7 free base)
T10217
synonym: PPI 149 Acetate,Abarelix Acetate
Target:
p-MPPI hydrochloride
T16421
synonym:
Target:
Bractoppin
T8873
synonym:
Target:
PPIase-Parvulin Inhibitor
T22135
synonym:
Target:
Poloppin
T24652
synonym:
Target:
3-MPPI
T37893
synonym:
Target:
Philippin A
TN6340
synonym:
Target:
DPPI 1c hydrochloride
T22747
synonym:
Target:
Flemiphilippinin A
TN1646
synonym:
Target:
M2I-1
T4647
synonym: M2I 1
Target:
MI-136
T6889
synonym:
Target:
IGS-1.76
T8784
synonym:
Target:
Ceftaroline fosamil
T7387
synonym: 头孢罗林酯,PPI0903,TAK-599
Target:
BMS-8
T26859
synonym:
Target:
HIV-1 Nef-IN-1
T9039
synonym:
Target:
SU3327
T13018
synonym:
Target:
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