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Synonyms: PN-II, PN2, CVAP, CTFgamma, APPI, AD1, ABPP, ABETA, AAA
Anti-APP Monoclonal Antibody
(7F543)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
| Description | Anti-APP Monoclonal Antibody (7F543) is a Mouse antibody targeting APP. Anti-APP Monoclonal Antibody (7F543) can be used in FCM. |
| Synonyms | PN-II, PN2, CVAP, CTFgamma, APPI, AD1, ABPP, ABETA, AAA |
| Ig Type | IgG2b |
| Clone | 7F543 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human APP (AA: 483-699) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | APP |
| Gene ID | |
| Protein Name | Amyloid-beta precursor protein |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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