nicotinic

Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.

Acipimox (K-9321) is a niacin derivative and nicotinic acid analog with activity as a hypolipidemic agent. Acipimox has special application for the treatment of hyperlipidemia in non-insulin-dependent diabetic patients.

Arecoline hydrobromide (Arecoline HBr) is a muscarinic acetylcholine receptor agonist.

The quinuclidine PHA 568487 free base is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated liabilities with in vivo tolerability.

TQS (4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) is a positive allosteric modulator of α7 nACh receptors.

Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable agonist of the nicotinic acetylcholine receptor (nAChR) with a Ki of 16.7 nM.

Hemicholinium 3 is a potent and selective choline uptake blocker.

Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM). Facinicline hydrochloride improves cognition and sensorimotor gating in rodents.

Myosmine is a minor tobacco alkaloid that is structurally related to nicotine.

suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = 1.5 nM) with antidepressant activity.

Nicotinic acid N-oxide (Nicotinic acid 1-oxide) is a nicotinic acid derivative, used to treat hyperlipoidemia.

Nicotinic acid hydrazide (NAH) is a hydrazide derivative of nicotinic acid, a heterocyclic organic compound. It is a peroxidase inhibitor and can form solid metal complexes with strong biological activity.

Compound FL0181, with CAS No. 158063-66-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0181 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

6-(DIMETHYLAMINO)NICOTINIC ACID, with CAS No. 82846-28-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 6-(DIMETHYLAMINO)NICOTINIC ACID provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Nicotinic acid mononucleotide is composed of nicotinic acid, ribose, and phosphate groups, serving as a key intermediate in the intracellular synthesis of NAD+ (Coenzyme 1), closely associated with cellular metabolism.

Nicotinic anhydride is an agent of biochemical.

Nicotinic Acid Adenine Dinucleotide is a precursor of NAD (Nicotinamide adenine dinucleotide) and a substrate for glutamine-dependent NAD+ synthase, widely used in biochemical experiments and drug synthesis research.

Nicotinic acid riboside is a natural product and a precursor of NAD+, maintaining NAD+ homeostasis, regulating Nrf-2/P62-related oxidative stress and autophagy, reducing MDA, LDH, and ROS levels, and promoting cardiac SOD and glutathione (GSH) activity.

6-(Trifluoromethyl)nicotinic acid is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Isonicotinic acid, a metabolite of isoniazid and a useful isomer of nicotinic acid, is formed from isoniazid by hydrazinolysis and can be catalyzed by cytochrome P450 enzymes, such as CYP2C.

6-Hydroxynicotinic acid (6-Hydroxypyridine-3-carboxylic acid) is exploited in the use of NMR spectroscopy or gas chromatography--mass spectrometry for the diagnosis of Pseudomonas aeruginosa in urinary tract infection. Among the common bacteria causing urinary infection, only P. aeruginosa produces 6-hydroxynicotinic acid from nicotinic acid.

Compound Fr12733, with CAS No. 38496-18-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12733 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr12734, with CAS No. 5398-44-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12734 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr13166, with CAS No. 82671-06-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13166 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.