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Results for "

bioactive

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    1865
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    TargetMol | Inhibitors_Agonists
Curcumol
(-)-Curcumol
T28534871-97-0
Curcumol ((-)-Curcumol), a pure monomer derived from Rhizoma Curcumaeis, exhibits antitumor activities.
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Phyllanthin
TN206210351-88-9
Phyllanthin is widely used as hepatoprotective and antigenotoxic and inhibit function of P-gp.
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Salidroside
Rhodioloside
T271710338-51-9
Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola rosea and is a prolyl endopeptidase inhibitor. Salidroside can alleviate cachexia symptoms in a tumor cachexia mouse model by activating mTOR signaling and protect dopaminergic neurons by enhancing PINK1 Parkin-mediated mitochondrial autophagy. Salidroside can also inhibit the growth of cancer cells by regulating the CDK4-cyclin D1 pathway to block the G1 phase and or regulating the Cdc2-cyclin B1 pathway to block the G2 phase.
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TargetMol | Inhibitor Hot
Astragaloside IV
AST-IV, AS-IV
T297384687-43-4
Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1 2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells. Astragaloside IV is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine.1 It dose-dependently inhibits human adenovirus type 3 (HAdV-3) in A549 cells (IC50 = 23 μM; LC50 = 865 μM).It inhibits replication of HAdV-3 and decreases HAdV-3-induced apoptosis. It has diverse protective effects for the cardiovascular, immune, digestive, and nervous systems. In particular, it reduces myocardial infarct size in dogs when administered prior to coronary ligation and reduces reperfusion arrhythmias in isolated rat hearts.
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18β-Glycyrrhetinic acid
Glycyrrhetin, Enoxolone
T0036471-53-4
18β-Glycyrrhetinic acid (Enoxolone) is the major bioactive component of Glycyrrhizae Radix and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties.
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Bilobalide
(-)-Bilobalide
T280833570-04-6
Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.
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Spiculisporic Acid
4,5-dicarboxy-4-pentadecanolide
T2828469-77-2
Spiculisporic Acid (4,5-dicarboxy-4-pentadecanolide) is a bioactive γ-butenolide isolated from a marine Aspergillus.
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Naringenin
S-Dihydrogenistein, Salipurol, Pelargidanon, NSC 34875, NSC 11855, Naringetol
T2838480-41-1
Naringenin (NSC-11855) is a flavanone that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, antiinflammatory, carbohydrate metabolism promoter, immunity system modulater. This substance has also been shown to repair DNA.
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Taurochenodeoxycholic Acid
TCDCA, Taurochenodeoxycholate, Chenyltaurine, Chenodeoxycholyltaurine, 12-Deoxycholyltaurine
T2A2481516-35-8
Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.
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1,3-Dimethylpyrazole
2,5-Dimethylpyrazole, 1,3-Dimethyl-1H-pyrazole
T40807694-48-4
1,3-Dimethylpyrazole (2,5-Dimethylpyrazole) is a bioactive compound isolated from Moso Bamboo Root.
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Cyclic N-Acetyl-D-mannosamine
2-ACETAMIDO-2-DEOXY-D-MANNOPYRANOSE HYDRATE
T47257772-94-3
Cyclic N-Acetyl-D-mannosamine is a monosaccharide used as a precursor in the chemical or enzymatic synthesis of neuraminic acid found in glycolipids and glycoproteins.N-Acetyl-D-mannosamine is a specific substrate for the synthesis of n -acetylneuraminic acid, an essential precursor for bacterial podoplanar polysialic acid (PA).N-Acetyl-D-mannosamine is used in the synthesis of sialic acid. mannosamine is used in the synthesis of sialic acid. It is also an intermediate in the synthesis of many carbohydrate-derived bioactive compound families and drug candidates.N-Acetyl-D-mannosamine is used in the study of cognitive disorders and aging.
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Agmatine sulfate
Agmatine sulfate salt
T48082482-00-0
Agmatine sulfate (Agmatine sulfate salt) is a bioactive metabolite of the arginine amino acid. It exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide synthesis. It is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor.
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Allyl Methyl Sulfide
T557910152-76-8
Allyl Methyl Sulfide is a bioactive organosulfur compound found in garlic with antibacterial, antioxidant, and anticancer activities.
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Caffeic Acid Phenethyl Ester
Phenylethyl Caffeate, CAPE
T6429104594-70-9
Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective and immunomodulating activities. CAPE is the phenethyl alcohol ester of caffeic acid and a bioactive component of honeybee hive propolis. In addition, CAPE inhibits PDGF-induced proliferation of vascular smooth muscle cells through the activation of p38 mitogen-activated protein kinase (MAPK) and hypoxia-inducible factor (HIF)-1alpha and subsequent induction of heme oxygenase-1 (HO-1).
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Taurochenodeoxycholic acid sodium
Sodium taurochenodeoxycholate
TN22156009-98-9
Taurochenodeoxycholic acid sodium (Sodium taurochenodeoxycholate) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and immune regulation properties. It can increase glucose-induced insulin secretion and stimulate the electrical activity of α2-cells and enhance cytosolic Ca(2+) concentration ([Ca(2+)](c)).
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Patchouli alcohol
Patchouli camphor, Patchoulol, (-)-Patchouli Alcohol
T29165986-55-0
Patchouli alcohol (Patchoulol) is a naturally occurring tricyclic sesquiterpenoid found in patchouli oil. It is a key bioactive component known for its immunomodulatory, anti-inflammatory, antioxidant, antitumor, antibacterial, anti-atherosclerotic, antiemetic, and sedative properties.
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Corylin
T6S014153947-92-5
Corylin is a major bioactive compound isolated from Psoralea corylifolia L; it has the activity of antibiotic or anticancer.
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NITIDINE
T88596872-57-7
Nitidine is a bioactive plant benzophenanthridine alkaloid isolated from the root of Zanthoxylum nitidum. It shows anticancer, neuroprotective, antimalarial, anti-HIV, analgesic, anti-inflammatory and antifungal activities.
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Millepachine
T388151393922-01-4
Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.
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Benzylamine
T4846100-46-9
Benzylamine, a bioactive alkaloid derived from Moringa oleifera (horseradish tree), is present in apples.
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Larixyl acetate
TN44174608-49-5
Larixyl acetate is a bioactive chemical.
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Phthalic acid mono-2-ethylhexyl ester
Phthalic Acid Monooctyl Ester, DEHP
T06034376-20-9
Phthalic acid mono-2-ethylhexyl ester (Phthalic Acid Monooctyl Ester) is a major bioactive metabolite of diethylhexyl phthalate (DEHP), which inhibits the 17,20 lyase activity of CYP17. The Cyp17a1 gene is specifically targeted by MEHP, explaining the MEHP-induced suppression of steroidogenesis observed.
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Daphnin
T10959486-55-5
Daphnin is one of the main coumarin bioactive ingredients with antibacterial activity. Daphnine is isolated from the entire Daphne fragrance, which is a folk medicine used in China to relieve fever.
    7-10 days
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    Lycopodine
    T13764466-61-5
    Lycopodine, a bioactive compound derived from Lycopodium clavatum spores, effectively inhibits the proliferation of HeLa cells through the induction of apoptosis. This process is mediated by caspase-3 activation. In refractory prostate cancer cells, Lycopodine triggers apoptosis by modulating 5-lipoxygenase and depolarizing the mitochondrial membrane potential, without altering p53 activity.
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    10-14 weeks
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