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Search Results for " gra "

Targets

306

Compounds

66

Natural Products

31

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T3422 GRA Ex-25 GRA-Ex-25 Glucagon Receptor
GRA Ex-25 (GRA-Ex-25) is an inhibitor of glucagon receptor.
T13721 Homo-PROTAC cereblon degrader 1 Others , Ligand for E3 Ligase
Homo-PROTAC cereblon degrader 1 is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.
T31992 Granotapide CETP
Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic syndrome, obesity, diabetes mellitus, prediabetes mellitus, an...
TQ0292 Grapiprant AAT-007,RQ-00000007,CJ-023423 Prostaglandin Receptor
Grapiprant (AAT-007) is a selective EP4 receptor antagonist. Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor (IC50: 35 nM, Ki: 24 nM).
T35841 5-Benzyloxygramine Dopamine Receptor , 5-HT Receptor
5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities[1]. 5-benzyloxygramine stabilizes the N-NTD dimers through simultaneous hydrophobic inter...
T2239 Raltegravir potassium MK 0518 potassium salt,Raltegravir potassium salt HIV Protease , Integrase
Raltegravir potassium (MK 0518 potassium salt) salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.
T13847 PROTAC SGK3 degrader-1 SGK3-PROTAC1 SGK
PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC coupler that targets SGK3 and binds ligand to VH032 VHL, which induces degradation of endogenous SGK3.PROTAC SGK3 degrader-1 inhibits GDC0941-induced proliferation of can...
T3977 Lifitegrast SHP-606,SAR 1118 Integrin
Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.
T69753 HDAC6 degrader 9c HDAC
HDAC6 degrader 9c is a small molecule histone deacetylase 6 (HDAC6) degrader that can be used to study cancer or other diseases.
T6024 Zoligratinib FF284,CH5183284,Debio 1347 FGFR
Zoligratinib (CH5183284) is a selective and orally available FGFR inhibitor, which is for FGFR1(IC50=9.3 nM), FGFR2(IC50=7.6 nM), FGFR3(IC50=290), and FGFR4(IC50=22 nM), respectively.
T125901 14-Epiandrographolide
14-Epiandrographolide is a compound derived from the above-ground parts of Andrographis paniculata that induces cell differentiation and can be used in the study of multiple sclerosis.
T9236 WSB1 Degrader 1 Others , E1/E2/E3 Enzyme
WSB1 Degrader 1 is a poten and orally active WD repeat and SOCS box-containing 1 degrader. WSB1 Degrader 1 has anticancer metastatic effects
T39755 Pirmitegravir STP0404 HIV Protease
Pirmitegravir (STP0404) is a potent and selective inhibitor of allosteric integrase (ALLINI) targeting the LEDGF/p75 binding site. Pirmitegravir inhibits PBMC. Pirmitegravir inhibits PBMC.Pirmitegravir has significant an...
T30751 Carotegrast methyl AJM300 Integrin
Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.
T11074 Dolutegravir intermediate-1 1-(2,2-dimethoxyethyl)-5-methoxy-6-methoxycarbonyl-4-oxopyridine-3-carboxylic acid,1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid HIV Protease
Dolutegravir intermediate-1 (1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid) is a new synthetic Dolutegravir intermediate. Dolutegravir is an integrase inhibitor develope...
T2329 Dolutegravir sodium GSK1349572,GSK-1349572A HIV Protease
Dolutegravir sodium (GSK-1349572A) salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
T6098 Cabotegravir GSK744,GSK-1265744,S/GSK1265744 HIV Protease
Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (IC50: 3.0 nM).
T60742 HIV-1 integrase inhibitor 8 HIV Protease
HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1].
T4493 Bictegravir GS-9883 HIV Protease
Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase (IC50: 7.5 nM).
TP1497L Mast Cell Degranulating Peptide HR-2 acetate Mast Cell Degranulating Peptide HR-2 acetate(80388-04-1 free base) Others
Mast Cell Degranulating Peptide HR-2 acetate from giant hornet Vespa orientalis that has biological effects similar to mast cell degranulating peptide from bee venom.
T16364 Infigratinib phosphate NVP-BGJ398 phosphate,BGJ-398 phosphate FGFR
Infigratinib phosphate (BGJ-398 phosphate) is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively).
T1975 Infigratinib BGJ-398,NVP-BGJ398 Apoptosis , FGFR
Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and VEGFR2.
T13722 Homo-PROTAC pVHL30 degrader 1 Others , Ligand for E3 Ligase
Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC.
T9013 Autogramin-2 tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Autophagy
Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) potently inhibits autophagy induced by either starvation with IC50 of 0.27 μM, and inhibits mTORC1 (Rapamycin; IC50...
T6198 Dolutegravir S/GSK1349572,GSK1349572 HIV Protease
Dolutegravir (GSK1349572) (IC50=2.7 nM), a two-metal-binding HIV integrase inhibitor, exhibits medium activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
T35340 Bictegravir Sodium GS-9883 Sodium HIV Protease
Bictegravir Sodium (GS-9883 Sodium) is a potent inhibitor of HIV-1 integrase, with an IC50 of 7.5 nM. Bictegravir Sodium exhibits potent and selective anti-HIV activity and low cytotoxicity
T8745 PROTAC BRAF-V600E degrader-1 Compound 23 Raf
PROTAC BRAF-V600E degrader-1 (Compound 23) selectively induces degradation of BRAF-V600E but not wildtype BRAF.
T1042 Granisetron hydrochloride BRL 43694A,Granisetron HCl 5-HT Receptor
Granisetron hydrochloride (Granisetron HCl) is a serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy patients.
T10413 Autogramin-1 mTOR , Autophagy
Autogramin-1 potently inhibits autophagy induced by either mTORC1 inhibition (Rapamycin; IC50: 0.44 μM) or starvation (IC50: 0.17 μM).
TQ0291 Firategrast SB 683699 Integrin
Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity...
T4547 Grazoprevir MK-5172 HCV Protease , SARS-CoV
Grazoprevir (MK-5172) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0.08 nM (gt2a), 0.90 nM (gt3a), 0.01 nM (gt1b), ...
T2332 Elvitegravir GS-9137,EVG,D06677,JTK-303 HIV Protease
Elvitegravir (JTK-303) is a Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor. The mechanism of action of elvitegravir is as an HIV Integrase Inhibitor, and Cytochrome P450 2C9 Inducer.
T2239L Raltegravir MK-0518 HIV Protease , Integrase
Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV INFECTION.
T6300 Degrasyn WP1130 Apoptosis , JAK , Bcr-Abl , DUB , Autophagy
Degrasyn (WP1130) (WP1130), a specific deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor, also inhibits Bcr/Abl, which is a JAK2 transducer (without affecting 20S proteasome) and activator of transcri...
T8369 Adagrasib MRTX849 Ras
Adagrasib (MRTX849) is an orally active and selective covalent inhibitor of KRAS G12C. Adagrasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Adagrasib ...
T72162 HIV-1 integrase inhibitor 10
HIV-1 integrase inhibitor 10 is an orally active HIV-1 allosteric integrase inhibitor (ALLINI). HIV-1 integrase inhibitor 10 can inhibit viral outgrowth of the NLRepRluc virus in MT-2 cells with EC 50 values of 3-5 nM. H...
T74856 ER degrader 4
ER degrader 4 is a selective and orally active estrogen receptor degrader. ER degrader 4 has anti-tumor activity [1] .
T64284 PROTAC CDK12/13 Degrader-1
PROTAC CDK12/13 Degrader-1 (7f) is a potent and selective dual degrader of the cell cycle protein-dependent kinases CDK12 (DC50: 2.2 nM) and CDK13 (DC50: 2.1 nM). Breast cancer.
T62156 HIV-1 integrase inhibitor 9
HIV-1 integrase inhibitor 9 (compound 8a) is a potent inhibitor of HIV-1 RNase H (IC50: 12.3 μM) and has antiviral effects.
T79742 CARM1 degrader-2 Histone Methyltransferase
PROTAC CARM1 degrader-2 (compound 3e), with a DC50 value of 8.8 nM, is a VHL- and proteasome-dependent degrader of co-activator associated argininemethyltransferase (CARM1). It not only promotes the degradation of CARM1 ...
T79741 CARM1 degrader-1 Histone Methyltransferase
PROTAC CARM1 degrader-1 (compound 3b) serves as a highly potent degrader (DC50=8.1 nM) of the co-activator associated arginine methyltransferase (CARM1). This compound facilitates the degradation of CARM1 via the VHL-pro...
T80633 Androgen receptor degrader-1 Androgen Receptor
Androgen Receptor Degrader-1 (Compound 18) is a potent agent for androgen receptor degradation, applicable in cancer research [1].
T79148 PROTAC KRAS G12C degrader-3 Ras
PROTAC KRAS G12C Degrader-3 (Comp 283) serves as a potent degrader of KRAS G12C, utilized in cancer research [1].
T79383 ER degrader 7
ER degrader 7 (Compound 35t) is a selective degrader of both ERα and ERβ, and possesses activity as a tubulin polymerization inhibitor. It exhibits potent cell viability inhibition, with IC50 values of 0.06 μM for MCF-7,...
T79161 PROTAC PTPN2 degrader-2 TFA Phosphatase
PROTAC PTPN2 degrader-2 (example 187B) TFA is a potent degrader of Protein Tyrosine Phosphatase Non-receptor Type 2 (PTPN2), with potential applications in cancer and metabolic disease research [1].
T79160 PROTAC PTPN2 degrader-2 Phosphatase
PROTAC PTPN2 degrader-2 (example 187B) is a potent agent capable of degrading PTPN2, which holds potential for research in cancer and metabolic diseases [1].
T79505 PROTAC TG2 degrader-1 PROTACs
PROTAC TG2 Degrader-1 (Compound 11) is a VHL-based PROTAC that targets tissue transglutaminase (TG2) and exhibits a binding affinity with a K D of 68.9 μM. This compound effectively decreases TG2 levels in ovarian cancer...
T79067 PROTAC BTK Degrader-3 PROTACs
PROTAC BTK Degrader-3 is a potent degrader of Bruton's tyrosine kinase (BTK), exhibiting a DC50 (median degradation concentration) of 10.9 nM in Mino cells. This compound shows promise for research into B-cell malignanci...
T77931 PROTAC IRAK3 degrade-1 formic PROTACs
PROTAC IRAK3 Degrade-1 (Compound 23) is a selective and potent IRAK3 degrader, demonstrating an IC50 value of 5 nM [1].
T77974 PROTAC BCR-ABL Degrader-1 PROTACs
PROTAC BCR-ABL Degrader-1 (compound PROTAC 1), featuring a 2-oxoethyl linker, promotes Bcr-Abl degradation through the ubiquitin-proteasome pathway and demonstrates antiproliferative effects on K562 cells, suggesting its...

Compounds

GRA Ex-25
T3422
Synonym: GRA-Ex-25
Target: Glucagon Receptor
Homo-PROTAC cereblon degrader 1
T13721
Synonym:
Target: Others, Ligand for E3 Ligase
Granotapide
T31992
Synonym:
Target: CETP
Grapiprant
TQ0292
Synonym: AAT-007,RQ-00000007,CJ-023423
Target: Prostaglandin Receptor
5-Benzyloxygramine
T35841
Synonym:
Target: Dopamine Receptor, 5-HT Receptor
Raltegravir potassium
T2239
Synonym: MK 0518 potassium salt,Raltegravir potassium salt
Target: HIV Protease, Integrase
PROTAC SGK3 degrader-1
T13847
Synonym: SGK3-PROTAC1
Target: SGK
Lifitegrast
T3977
Synonym: SHP-606,SAR 1118
Target: Integrin
HDAC6 degrader 9c
T69753
Synonym:
Target: HDAC
Zoligratinib
T6024
Synonym: FF284,CH5183284,Debio 1347
Target: FGFR
14-Epiandrographolide
T125901
Synonym:
Target:
WSB1 Degrader 1
T9236
Synonym:
Target: Others, E1/E2/E3 Enzyme
Pirmitegravir
T39755
Synonym: STP0404
Target: HIV Protease
Carotegrast methyl
T30751
Synonym: AJM300
Target: Integrin
Dolutegravir intermediate-1
T11074
Synonym: 1-(2,2-dimethoxyethyl)-5-methoxy-6-methoxycarbonyl-4-oxopyridine-3-carboxylic acid,1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid
Target: HIV Protease
Dolutegravir sodium
T2329
Synonym: GSK1349572,GSK-1349572A
Target: HIV Protease
Cabotegravir
T6098
Synonym: GSK744,GSK-1265744,S/GSK1265744
Target: HIV Protease
HIV-1 integrase inhibitor 8
T60742
Synonym:
Target: HIV Protease
Bictegravir
T4493
Synonym: GS-9883
Target: HIV Protease
Mast Cell Degranulating Peptide HR-2 acetate
TP1497L
Synonym: Mast Cell Degranulating Peptide HR-2 acetate(80388-04-1 free base)
Target: Others
Infigratinib phosphate
T16364
Synonym: NVP-BGJ398 phosphate,BGJ-398 phosphate
Target: FGFR
Infigratinib
T1975
Synonym: BGJ-398,NVP-BGJ398
Target: Apoptosis, FGFR
Homo-PROTAC pVHL30 degrader 1
T13722
Synonym:
Target: Others, Ligand for E3 Ligase
Autogramin-2
T9013
Synonym: tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
Target: Autophagy
Dolutegravir
T6198
Synonym: S/GSK1349572,GSK1349572
Target: HIV Protease
Bictegravir Sodium
T35340
Synonym: GS-9883 Sodium
Target: HIV Protease
PROTAC BRAF-V600E degrader-1
T8745
Synonym: Compound 23
Target: Raf
Granisetron hydrochloride
T1042
Synonym: BRL 43694A,Granisetron HCl
Target: 5-HT Receptor
Autogramin-1
T10413
Synonym:
Target: mTOR, Autophagy
Firategrast
TQ0291
Synonym: SB 683699
Target: Integrin
Grazoprevir
T4547
Synonym: MK-5172
Target: HCV Protease, SARS-CoV
Elvitegravir
T2332
Synonym: GS-9137,EVG,D06677,JTK-303
Target: HIV Protease
Raltegravir
T2239L
Synonym: MK-0518
Target: HIV Protease, Integrase
Degrasyn
T6300
Synonym: WP1130
Target: Apoptosis, JAK, Bcr-Abl, DUB, Autophagy
Adagrasib
T8369
Synonym: MRTX849
Target: Ras
HIV-1 integrase inhibitor 10
T72162
Synonym:
Target:
ER degrader 4
T74856
Synonym:
Target:
PROTAC CDK12/13 Degrader-1
T64284
Synonym:
Target:
HIV-1 integrase inhibitor 9
T62156
Synonym:
Target:
CARM1 degrader-2
T79742
Synonym:
Target: Histone Methyltransferase
CARM1 degrader-1
T79741
Synonym:
Target: Histone Methyltransferase
Androgen receptor degrader-1
T80633
Synonym:
Target: Androgen Receptor
PROTAC KRAS G12C degrader-3
T79148
Synonym:
Target: Ras
ER degrader 7
T79383
Synonym:
Target:
PROTAC PTPN2 degrader-2 TFA
T79161
Synonym:
Target: Phosphatase
PROTAC PTPN2 degrader-2
T79160
Synonym:
Target: Phosphatase
PROTAC TG2 degrader-1
T79505
Synonym:
Target: PROTACs
PROTAC BTK Degrader-3
T79067
Synonym:
Target: PROTACs
PROTAC IRAK3 degrade-1 formic
T77931
Synonym:
Target: PROTACs
PROTAC BCR-ABL Degrader-1
T77974
Synonym:
Target: PROTACs
1 2 3 4 5 6 7
Cat No. Product Name Synonyms Targets
T5802 Stearyl glycyrrhetinate Antiviral , Antibacterial
Stearyl glycyrrhetinate, the stearyl ester of 18-β-glycyrrhetinic acid, has been demonstrated to improve antiviral effects, reduce inflammation and suppress allergies in the pharmaceutical and cosmetic industry.
TN7026 Acorus gramineus, ext. Others
Acorus gramineus, ext is a natural product isolated from Acorus gramineus.
T6520 Grape Seed Extract Grape Seed P.E. Apoptosis , Others
Grape Seed Extract (Grape Seed P.E.) is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites (BIOFLAVONOIDS and polyphenols) credited with important medicinal properties.
T3884 Neoandrographolide Neoandrographiside NOS , COX
Neoandrographolide (Neoandrographiside) has potent hypolipidemic effect and protects the cardiovascular without significant liver damage.Neoandrographolide has anti-inflammatory effect, might result from inhibition of iN...
TJS1748 Methyl protogracillin 山药 Antifection
Methyl protogracillin is a natural product from Dioscorea collettii var. hypoglauca with anti-cancer activity.
TQ0218 Deoxyandrographolide 14-deoxyandrographolide IL Receptor , TNF
Deoxyandrographolide (14-deoxyandrographolide) potentiates NGF-induced neurite outgrowth. Deoxyandrographolide suppresses the production of proinflammatory mediators TNF-α and IL-6.
TN6705 Graveoline 2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one,Foliosine Autophagy
Graveoline (2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one) is an apoptosis and autophagy inducer in skin melanoma cancer cells
TN7091 Isolugrandoside Others
Isolugrandoside is from the aerial parts of Digitalis davisiana Heywood.
T9218 Andrograpanin 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE p38 MAPK
Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties.
T2738 Dehydroandrographolide NOS , Influenza Virus
Dehydroandrographolide is a natural compound extracted from herbal medicine Andrographis paniculata (Burm f) Nees.
T1130 Gramicidin Gramicidinum,Gramicidine,Gramicidina MRP , Antibacterial , Antibiotic
A group of peptide antibiotics from BACILLUS brevis. Gramicidin (Gramicidine) C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is one of the two principal components of TYROTH...
T2898 Andrographolide Andrographis SARS-CoV , Influenza Virus , NF-κB , Autophagy
Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potential antineoplastic.
T8288 14-Deoxyandrographolide Apoptosis , Others
14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release.
TN1038 Galgravin Apoptosis
Galgravin has anti-inflammatory, and neuroprotective effects, it can promote neuronal survival and neurite outgrowth, protect hippocampal neurons against amyloid beta peptide (Abeta25-35)-induced cytotoxicity, and protec...
TQ0185 14-Deoxy-11,12-didehydroandrographolide AP10,14-dehydro Andrographolide NF-κB
14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.
T3667 Kalii Dehydrographolidi Succinas Ddhads,Dehydroandrographolide Succinate Potasium Salt Others
Kalii Dehydrographolidi Succinas (Dehydroandrographolide Succinate Potasium Salt) is a natural compound with anti-virus infection activity.
T3774 Gracillin 山药 cell cycle arrest
Gracillin can induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells, and has the potential to be developed as an antitumor agent. Gracillin can be selected as lead compounds for the development of new d...
T2S0257 Dehydroandrographolide succinate Others , Influenza Virus
Dehydroandrographolide Succinate is a traditional Chinese medicine used in the treatment of pneumonia, respiratory tract infection.
T2S0250 Pseudoprotogracillin 山药 Others
Pseudoprotogracillin is a steroidal saponin extracted from Dioscoreae.
T2S1749 Protogracillin 山药 Others
Protogracillin may have inhibitions on platelet aggregation (PAG) and thrombosis.
TN7092 Lugrandoside Others
Lugrandoside is a novel phenylpropanoid glycoside, lugrandoside, has been isolated from the caulinary leaves of Digitalis Lutea L. and Difitalis Grandiflora Miller.
T6519 Gramine NSC 16892,Donaxine Adiponectin receptor , Reverse Transcriptase , Adrenergic Receptor
Gramine (Donaxine), a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for AdipoR2 and AdipoR1, respectively. Gramine is als...
T8898 Granilin Graniline Others , Antibacterial , Antifungal
Granilin (Graniline)e is a natural product.
T40924 Tellimagrandin II Eugeniin
Tellimagrandin II (Eugeniin) is the initial intermediate in the 4 C 1 -glucose derived series of ellagitannins. Additionally, it possesses the ability to inhibit antibiotic resistance exhibited by drug-resistant Staphylo...
TN3411 Andrographidine C Others
Andrographidine C is a natural product of Andrographis, Acanthaceae. The catalog number is TN3411 and the CAS number is 113963-39-6. Andrographidine C can be used as a reference standard.
T31993 Grayanotoxin II G-II,Deacetylanhydroandromedotoxin,delta(sup 10 (18))-Andromedenol
Grayanotoxins are a group of closely related neurotoxins named after Leucothoe grayana. Extract from leaves of Ericaceae.
TN5586 14-Deoxy-12-hydroxyandrographolide
14-Deoxy-12-hydroxyandrographolide is a natural product of Andrographis, Acanthaceae. The catalog number is TN5586 and the CAS number is 219721-33-2. 14-Deoxy-12-hydroxyandrographolide can be used as a reference standard...
TN3605 Casegravol Others
Casegravol shows antiproliferative activity against human gastric adenocarcinoma (MK-1), human uterus carcinoma (HeLa), and murine melanoma (B16F10) cells.
TN5710 Integracin A
Integracin A is a natural product for research related to life sciences. The catalog number is TN5710 and the CAS number is 224186-03-2.
TN4078 Fragransin A2 Others
Fragransin A2 is a natural product of Myristica, Myristicaceae. The catalog number is TN4078 and the CAS number is 112652-46-7. Fragransin A2 can be used as a reference standard.
TN5430 Pomegralignan
Pomegralignan is a natural product for research related to life sciences. The catalog number is TN5430 and the CAS number is 1562492-32-3.
T41042 Gramicidin C
Gramicidin C is a naturally occuring polypeptide antibiotic isolated from B. brevis var. G.B.
T72580 Isoandrographolide
Isoandrographolide possesses cell differentiation inducing and hepatoprotective effect. Isoandrographolide inhibits NLRP3 inflammasome activation and attenuates silicosis in mice .
T82562 Dide-O-methylgrandisin
Dide-O-methylgrandisin, a neolignan of the diaryltetrahydrofuran class, is referenced as compound [1].
T20217 Grandiflorenic acid
Grandiflorenic acid can reproduce the uterine responses induced by aqueous extract of zoapatle leaves. It is suggested that grandiflorenic acid may have an antifertility effect.
TN4165 Grayanotoxin I Others
Grayanotoxin I is a natural product for research related to life sciences. The catalog number is TN4165 and the CAS number is 4720-09-6.
TN6599 Andrographidine A
Andrographidine A is a natural product for research related to life sciences. The catalog number is TN6599 and the CAS number is 113963-37-4.
TN2623 14-Deoxy-17-hydroxyandrographolide Antifection
14-Deoxy-17-hydroxyandrographolide is a natural product of Andrographis, Acanthaceae. The catalog number is TN2623 and the CAS number is 869384-82-7. 14-Deoxy-17-hydroxyandrographolide can be used as a reference standard...
TN3429 Aphagranin A Others
Aphagranin A exhibits strong antiproliferative activity against the growth of six lines of human cancer cells (MCF-7, A549, HepG2, Bel-7402, SGC-7901, and BGC-823.
TN2291 Uvarigranol B Others
Uvarigranol B is a natural product
TN4164 Grandifloroside TNF
Grandifloroside shows good antioxidative and potent anti-inflammatory activities, it also exhibits potent inhibitory activity against TNF-α and 5α-reductase, suggests that it might be developed as a source of potent anti...
TN3412 Andrographiside Others
Andrographiside shows protective effects on hepatotoxicity induced in mice by carbon tetrachloride or tert-butylhydroperoxide (tBHP) intoxication, the effects could be due to its glucoside groups which may act as strong ...
TN2463 14-Deoxy-11-oxoandrographolide Others
14-Deoxy-11-oxoandrographolide is a natural product from Andrographis paniculata
TN2602 12-Oxograndiflorenic acid Others
12-Oxograndiflorenic acid is a natural product that can be extracted from Anemone and Porphyra and is cytotoxic to some cells.
TN5585 14-Deoxy-11-hydroxyandrographolide
14-Deoxy-11-hydroxyandrographolide shows potent cell differentiation-inducing activity towards mouse myeloid leukemia (M1) cells.
TN2605 12alpha-Hydroxygrandiflorenic acid Others
12alpha-Hydroxygrandiflorenic acid is a natural product of Wedelia, Asteraceae. The catalog number is TN2605 and the CAS number is 63768-17-2. 12alpha-Hydroxygrandiflorenic acid can be used as a reference standard.
TN4163 Grandifloric acid Others
Grandifloric acid is a natural product of Siegesbeckia, Asteraceae. The catalog number is TN4163 and the CAS number is 22338-69-8. Grandifloric acid can be used as a reference standard.
TN3813 Delgrandine Others
Delgrandine is a natural product of Delphinium, Ranunculaceae. The catalog number is TN3813 and the CAS number is 145237-05-4. Delgrandine can be used as a reference standard.
TN5387 Grasshopper ketone ERK , p38 MAPK , NO Synthase , JNK
Grasshopper ketone, isolated from the brown alga Sargassum, is a potent inhibitor of LPS-induced NO production in RAW 264.7 cells and induces anti-inflammatory effects by inhibiting MAPK (ERK, JNK and p38) and NF-κB p65 ...
T13582 Bisandrographolide C Others
Bisandrographolide C is identified from Andrographis paniculata. Bisandrographolide C activates TRPV1 and TRPV3 channels (Kds: 289 and 341 μM) and protects cardiomyocytes from hypoxia-reoxygenation injury.
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Natural Products

Stearyl glycyrrhetinate
T5802
Synonym:
Target: Antiviral, Antibacterial
Acorus gramineus, ext.
TN7026
Synonym:
Target: Others
Grape Seed Extract
T6520
Synonym: Grape Seed P.E.
Target: Apoptosis, Others
Neoandrographolide
T3884
Synonym: Neoandrographiside
Target: NOS, COX
Methyl protogracillin
TJS1748
Synonym: 山药
Target: Antifection
Deoxyandrographolide
TQ0218
Synonym: 14-deoxyandrographolide
Target: IL Receptor, TNF
Graveoline
TN6705
Synonym: 2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one,Foliosine
Target: Autophagy
Isolugrandoside
TN7091
Synonym:
Target: Others
Andrograpanin
T9218
Synonym: 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE
Target: p38 MAPK
Dehydroandrographolide
T2738
Synonym:
Target: NOS, Influenza Virus
Gramicidin
T1130
Synonym: Gramicidinum,Gramicidine,Gramicidina
Target: MRP, Antibacterial, Antibiotic
Andrographolide
T2898
Synonym: Andrographis
Target: SARS-CoV, Influenza Virus, NF-κB, Autophagy
14-Deoxyandrographolide
T8288
Synonym:
Target: Apoptosis, Others
Galgravin
TN1038
Synonym:
Target: Apoptosis
14-Deoxy-11,12-didehydroandrographolide
TQ0185
Synonym: AP10,14-dehydro Andrographolide
Target: NF-κB
Kalii Dehydrographolidi Succinas
T3667
Synonym: Ddhads,Dehydroandrographolide Succinate Potasium Salt
Target: Others
Gracillin
T3774
Synonym: 山药
Target: cell cycle arrest
Dehydroandrographolide succinate
T2S0257
Synonym:
Target: Others, Influenza Virus
Pseudoprotogracillin
T2S0250
Synonym: 山药
Target: Others
Protogracillin
T2S1749
Synonym: 山药
Target: Others
Lugrandoside
TN7092
Synonym:
Target: Others
Gramine
T6519
Synonym: NSC 16892,Donaxine
Target: Adiponectin receptor, Reverse Transcriptase, Adrenergic Receptor
Granilin
T8898
Synonym: Graniline
Target: Others, Antibacterial, Antifungal
Tellimagrandin II
T40924
Synonym: Eugeniin
Target:
Andrographidine C
TN3411
Synonym:
Target: Others
Grayanotoxin II
T31993
Synonym: G-II,Deacetylanhydroandromedotoxin,delta(sup 10 (18))-Andromedenol
Target:
14-Deoxy-12-hydroxyandrographolide
TN5586
Synonym:
Target:
Casegravol
TN3605
Synonym:
Target: Others
Integracin A
TN5710
Synonym:
Target:
Fragransin A2
TN4078
Synonym:
Target: Others
Pomegralignan
TN5430
Synonym:
Target:
Gramicidin C
T41042
Synonym:
Target:
Isoandrographolide
T72580
Synonym:
Target:
Dide-O-methylgrandisin
T82562
Synonym:
Target:
Grandiflorenic acid
T20217
Synonym:
Target:
Grayanotoxin I
TN4165
Synonym:
Target: Others
Andrographidine A
TN6599
Synonym:
Target:
14-Deoxy-17-hydroxyandrographolide
TN2623
Synonym:
Target: Antifection
Aphagranin A
TN3429
Synonym:
Target: Others
Uvarigranol B
TN2291
Synonym:
Target: Others
Grandifloroside
TN4164
Synonym:
Target: TNF
Andrographiside
TN3412
Synonym:
Target: Others
14-Deoxy-11-oxoandrographolide
TN2463
Synonym:
Target: Others
12-Oxograndiflorenic acid
TN2602
Synonym:
Target: Others
14-Deoxy-11-hydroxyandrographolide
TN5585
Synonym:
Target:
12alpha-Hydroxygrandiflorenic acid
TN2605
Synonym:
Target: Others
Grandifloric acid
TN4163
Synonym:
Target: Others
Delgrandine
TN3813
Synonym:
Target: Others
Grasshopper ketone
TN5387
Synonym:
Target: ERK, p38 MAPK, NO Synthase, JNK
Bisandrographolide C
T13582
Synonym:
Target: Others

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-05159 Granzyme A/GZMA Protein, Human, Recombinant (His) Human HEK293
TMPY-00817 Granzyme B/GZMB Protein, Human, Recombinant (His) Human HEK293
Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ...
TMPY-00978 Progranulin Protein, Human, Recombinant (His) Human HEK293
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The precursor protein, progranulin, ...
TMPJ-00925 Grancalcin Protein, Human, Recombinant Human E. coli
Grancalcin (GCA) is a cytoplasmic granule membrane protein that contains 4 EF-hand domains. GCA is calcium-binding protein and particularly abundant in human neutrophils. GCA is highly expressed in bone marrow, and it ca...
TMPK-00673 SG3/Secretogranin 3 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regu...
TMPH-03633 GRA2 Protein, Toxoplasma gondii, Recombinant (His & Myc) Toxoplasma gondii E. coli
TMPH-03632 GRA1 Protein, Toxoplasma gondii, Recombinant (His) Toxoplasma gondii E. coli
TMPH-00070 Major allergen Api g 1, isoallergen 2 Protein, Apium graveolens, Recombinant (His) Apium graveolens E. coli
TMPH-03368 SG3/Secretogranin 3 Protein, Rat, Recombinant (His & Myc) Rat E. coli
TMPH-01412 Granzyme B Protein, Human, Recombinant (E. coli, His) Human E. coli
Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target pr...
TMPH-03634 GRA3 Protein, Toxoplasma gondii, Recombinant (His) Toxoplasma gondii E. coli
TMPY-00818 Granzyme H/GZMH Protein, Human, Recombinant (His) Human HEK293
Granzymes are key components of the immune response that play important roles in eliminating host cells infected by intracellular pathogens. Several granzymes are potent inducers of cell death. A total of eight granzymes...
TMPJ-00770 Granzyme B/GZMB Protein, Mouse, Recombinant (His) Mouse Human Cells
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an...
TMPY-03994 SG3/Secretogranin 3 Protein, Human, Recombinant (His) Human HEK293
SCG3, also known as secretogranin 3, is a member of the chromogranin/secretogranin family. Members of this family may serve as precursors for biologically active peptides. SCG3 is transported to secretory granules (SGs) ...
TMPK-01122 SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His) Human HEK293
Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regu...
TMPJ-00832 Granzyme D/GZMD Protein, Mouse, Recombinant (His) Mouse Human Cells
Granzyme D is a member of the granzyme family of the serine proteases which plays a role in the induction of apoptosis. T cells, lymphohematopoietic stromal cells, and granulated metrial gland cells express granzyme D, b...
TMPY-01435 Progranulin Protein, Mouse, Recombinant (His) Mouse HEK293
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The precursor protein, progranulin, ...
TMPH-03159 DODA Protein, Portulaca grandiflora, Recombinant (His & Myc & SUMO) Portulaca grandiflora E. coli
Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both...
TMPH-02068 Secretogranin-1 Protein, Human, Recombinant (GST & His) Human E. coli
Functions as a GC-rich promoter-specific transactivating transcription factor.
TMPH-02688 Granzyme C/GZMC Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Acts as a chaperone.
TMPH-00069 Major allergen Api g 1, isoallergen 1 Protein, Apium graveolens, Recombinant (His & SUMO) Apium graveolens E. coli
TMPY-06547 Granulysin Protein, Human, Recombinant (hFc) Human HEK293
TMPY-06567 Granzyme K/GZMK Protein, Human, Recombinant (His) Human HEK293
TMPY-03968 Secretogranin II Protein, Human, Recombinant (His) Human HEK293
Kit ligand, also known as Hematopoietic growth factor KL, Mast cell growth factor, Steel factor, Stem cell factor, c-Kit ligand, Kitlg and KITL, is a single-pass type I membrane protein that belongs to the SCF family. KI...
TMPY-04675 SG3/Secretogranin 3, Mouse, Recombinant (His) Mouse HEK293
SCG3, also known as secretogranin 3, is a member of the chromogranin/secretogranin family. Members of this family may serve as precursors for biologically active peptides. SCG3 is transported to secretory granules (SGs) ...
TMPH-02452 Measles virus (MeV) (strain Leningrad-16) Fusion glycoprotein F0 (Avi & His) MeV in vitro E. coli expression system
TMPH-02687 Granzyme A/GZMA Protein, Mouse, Recombinant (His) Mouse E. coli
Acts as a chaperone.
TMPH-02689 Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macro...
TMPH-02069 Secretogranin-2 Protein, Human, Recombinant (GST & His) Human E. coli
Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mito...
TMPH-00755 Integrase Protein, Escherichia phage lambda, Recombinant (His) Escherichia phage lambda E. coli
TMPH-03635 GRA6 Protein, Toxoplasma gondii, Recombinant (GST) TOV-Toxoplasma gondii E. coli
Granzyme A/GZMA Protein, Human, Recombinant (His)
TMPY-05159
Species: Human
Expression System: HEK293
Granzyme B/GZMB Protein, Human, Recombinant (His)
TMPY-00817
Species: Human
Expression System: HEK293
Progranulin Protein, Human, Recombinant (His)
TMPY-00978
Species: Human
Expression System: HEK293
Grancalcin Protein, Human, Recombinant
TMPJ-00925
Species: Human
Expression System: E. coli
SG3/Secretogranin 3 Protein, Cynomolgus, Recombinant (His)
TMPK-00673
Species: Cynomolgus
Expression System: HEK293
GRA2 Protein, Toxoplasma gondii, Recombinant (His & Myc)
TMPH-03633
Species: Toxoplasma gondii
Expression System: E. coli
GRA1 Protein, Toxoplasma gondii, Recombinant (His)
TMPH-03632
Species: Toxoplasma gondii
Expression System: E. coli
Major allergen Api g 1, isoallergen 2 Protein, Apium graveolens, Recombinant (His)
TMPH-00070
Species: Apium graveolens
Expression System: E. coli
SG3/Secretogranin 3 Protein, Rat, Recombinant (His & Myc)
TMPH-03368
Species: Rat
Expression System: E. coli
Granzyme B Protein, Human, Recombinant (E. coli, His)
TMPH-01412
Species: Human
Expression System: E. coli
GRA3 Protein, Toxoplasma gondii, Recombinant (His)
TMPH-03634
Species: Toxoplasma gondii
Expression System: E. coli
Granzyme H/GZMH Protein, Human, Recombinant (His)
TMPY-00818
Species: Human
Expression System: HEK293
Granzyme B/GZMB Protein, Mouse, Recombinant (His)
TMPJ-00770
Species: Mouse
Expression System: Human Cells
SG3/Secretogranin 3 Protein, Human, Recombinant (His)
TMPY-03994
Species: Human
Expression System: HEK293
SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His)
TMPK-01122
Species: Human
Expression System: HEK293
Granzyme D/GZMD Protein, Mouse, Recombinant (His)
TMPJ-00832
Species: Mouse
Expression System: Human Cells
Progranulin Protein, Mouse, Recombinant (His)
TMPY-01435
Species: Mouse
Expression System: HEK293
DODA Protein, Portulaca grandiflora, Recombinant (His & Myc & SUMO)
TMPH-03159
Species: Portulaca grandiflora
Expression System: E. coli
Secretogranin-1 Protein, Human, Recombinant (GST & His)
TMPH-02068
Species: Human
Expression System: E. coli
Granzyme C/GZMC Protein, Mouse, Recombinant (His & Myc)
TMPH-02688
Species: Mouse
Expression System: E. coli
Major allergen Api g 1, isoallergen 1 Protein, Apium graveolens, Recombinant (His & SUMO)
TMPH-00069
Species: Apium graveolens
Expression System: E. coli
Granulysin Protein, Human, Recombinant (hFc)
TMPY-06547
Species: Human
Expression System: HEK293
Granzyme K/GZMK Protein, Human, Recombinant (His)
TMPY-06567
Species: Human
Expression System: HEK293
Secretogranin II Protein, Human, Recombinant (His)
TMPY-03968
Species: Human
Expression System: HEK293
SG3/Secretogranin 3, Mouse, Recombinant (His)
TMPY-04675
Species: Mouse
Expression System: HEK293
Measles virus (MeV) (strain Leningrad-16) Fusion glycoprotein F0 (Avi & His)
TMPH-02452
Species: MeV
Expression System: in vitro E. coli expression system
Granzyme A/GZMA Protein, Mouse, Recombinant (His)
TMPH-02687
Species: Mouse
Expression System: E. coli
Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc)
TMPH-02689
Species: Mouse
Expression System: E. coli
Secretogranin-2 Protein, Human, Recombinant (GST & His)
TMPH-02069
Species: Human
Expression System: E. coli
Integrase Protein, Escherichia phage lambda, Recombinant (His)
TMPH-00755
Species: Escherichia phage lambda
Expression System: E. coli
GRA6 Protein, Toxoplasma gondii, Recombinant (GST)
TMPH-03635
Species: TOV-Toxoplasma gondii
Expression System: E. coli
Cat No. Product Name
L8110 Reprogramming Compound Library

1840 compounds
A unique collection of 1840 reprogramming signaling pathway-related bioactive small molecule compounds for high-throughput, high-content screening.
TargetMol