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Cat No. | Product Name | Synonyms | Targets |
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T3422 | GRA Ex-25 | GRA-Ex-25 | Glucagon Receptor |
GRA Ex-25 (GRA-Ex-25) is an inhibitor of glucagon receptor. | |||
T13721 | Homo-PROTAC cereblon degrader 1 | Others , Ligand for E3 Ligase | |
Homo-PROTAC cereblon degrader 1 is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3. | |||
T31992 | Granotapide | CETP | |
Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic syndrome, obesity, diabetes mellitus, prediabetes mellitus, an... | |||
TQ0292 | Grapiprant | AAT-007,RQ-00000007,CJ-023423 | Prostaglandin Receptor |
Grapiprant (AAT-007) is a selective EP4 receptor antagonist. Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor (IC50: 35 nM, Ki: 24 nM). | |||
T35841 | 5-Benzyloxygramine | Dopamine Receptor , 5-HT Receptor | |
5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities[1]. 5-benzyloxygramine stabilizes the N-NTD dimers through simultaneous hydrophobic inter... | |||
T2239 | Raltegravir potassium | MK 0518 potassium salt,Raltegravir potassium salt | HIV Protease , Integrase |
Raltegravir potassium (MK 0518 potassium salt) salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection. | |||
T13847 | PROTAC SGK3 degrader-1 | SGK3-PROTAC1 | SGK |
PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC coupler that targets SGK3 and binds ligand to VH032 VHL, which induces degradation of endogenous SGK3.PROTAC SGK3 degrader-1 inhibits GDC0941-induced proliferation of can... | |||
T3977 | Lifitegrast | SHP-606,SAR 1118 | Integrin |
Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist. | |||
T69753 | HDAC6 degrader 9c | HDAC | |
HDAC6 degrader 9c is a small molecule histone deacetylase 6 (HDAC6) degrader that can be used to study cancer or other diseases. | |||
T6024 | Zoligratinib | FF284,CH5183284,Debio 1347 | FGFR |
Zoligratinib (CH5183284) is a selective and orally available FGFR inhibitor, which is for FGFR1(IC50=9.3 nM), FGFR2(IC50=7.6 nM), FGFR3(IC50=290), and FGFR4(IC50=22 nM), respectively. | |||
T125901 | 14-Epiandrographolide | ||
14-Epiandrographolide is a compound derived from the above-ground parts of Andrographis paniculata that induces cell differentiation and can be used in the study of multiple sclerosis. | |||
T9236 | WSB1 Degrader 1 | Others , E1/E2/E3 Enzyme | |
WSB1 Degrader 1 is a poten and orally active WD repeat and SOCS box-containing 1 degrader. WSB1 Degrader 1 has anticancer metastatic effects | |||
T39755 | Pirmitegravir | STP0404 | HIV Protease |
Pirmitegravir (STP0404) is a potent and selective inhibitor of allosteric integrase (ALLINI) targeting the LEDGF/p75 binding site. Pirmitegravir inhibits PBMC. Pirmitegravir inhibits PBMC.Pirmitegravir has significant an... | |||
T30751 | Carotegrast methyl | AJM300 | Integrin |
Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist. | |||
T11074 | Dolutegravir intermediate-1 | 1-(2,2-dimethoxyethyl)-5-methoxy-6-methoxycarbonyl-4-oxopyridine-3-carboxylic acid,1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid | HIV Protease |
Dolutegravir intermediate-1 (1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid) is a new synthetic Dolutegravir intermediate. Dolutegravir is an integrase inhibitor develope... | |||
T2329 | Dolutegravir sodium | GSK1349572,GSK-1349572A | HIV Protease |
Dolutegravir sodium (GSK-1349572A) salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. | |||
T6098 | Cabotegravir | GSK744,GSK-1265744,S/GSK1265744 | HIV Protease |
Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (IC50: 3.0 nM). | |||
T60742 | HIV-1 integrase inhibitor 8 | HIV Protease | |
HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1]. | |||
T4493 | Bictegravir | GS-9883 | HIV Protease |
Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase (IC50: 7.5 nM). | |||
TP1497L | Mast Cell Degranulating Peptide HR-2 acetate | Mast Cell Degranulating Peptide HR-2 acetate(80388-04-1 free base) | Others |
Mast Cell Degranulating Peptide HR-2 acetate from giant hornet Vespa orientalis that has biological effects similar to mast cell degranulating peptide from bee venom. | |||
T16364 | Infigratinib phosphate | NVP-BGJ398 phosphate,BGJ-398 phosphate | FGFR |
Infigratinib phosphate (BGJ-398 phosphate) is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively). | |||
T1975 | Infigratinib | BGJ-398,NVP-BGJ398 | Apoptosis , FGFR |
Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and VEGFR2. | |||
T13722 | Homo-PROTAC pVHL30 degrader 1 | Others , Ligand for E3 Ligase | |
Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC. | |||
T9013 | Autogramin-2 | tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate | Autophagy |
Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) potently inhibits autophagy induced by either starvation with IC50 of 0.27 μM, and inhibits mTORC1 (Rapamycin; IC50... | |||
T6198 | Dolutegravir | S/GSK1349572,GSK1349572 | HIV Protease |
Dolutegravir (GSK1349572) (IC50=2.7 nM), a two-metal-binding HIV integrase inhibitor, exhibits medium activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. | |||
T35340 | Bictegravir Sodium | GS-9883 Sodium | HIV Protease |
Bictegravir Sodium (GS-9883 Sodium) is a potent inhibitor of HIV-1 integrase, with an IC50 of 7.5 nM. Bictegravir Sodium exhibits potent and selective anti-HIV activity and low cytotoxicity | |||
T8745 | PROTAC BRAF-V600E degrader-1 | Compound 23 | Raf |
PROTAC BRAF-V600E degrader-1 (Compound 23) selectively induces degradation of BRAF-V600E but not wildtype BRAF. | |||
T1042 | Granisetron hydrochloride | BRL 43694A,Granisetron HCl | 5-HT Receptor |
Granisetron hydrochloride (Granisetron HCl) is a serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy patients. | |||
T10413 | Autogramin-1 | mTOR , Autophagy | |
Autogramin-1 potently inhibits autophagy induced by either mTORC1 inhibition (Rapamycin; IC50: 0.44 μM) or starvation (IC50: 0.17 μM). | |||
TQ0291 | Firategrast | SB 683699 | Integrin |
Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity... | |||
T4547 | Grazoprevir | MK-5172 | HCV Protease , SARS-CoV |
Grazoprevir (MK-5172) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0.08 nM (gt2a), 0.90 nM (gt3a), 0.01 nM (gt1b), ... | |||
T2332 | Elvitegravir | GS-9137,EVG,D06677,JTK-303 | HIV Protease |
Elvitegravir (JTK-303) is a Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor. The mechanism of action of elvitegravir is as an HIV Integrase Inhibitor, and Cytochrome P450 2C9 Inducer. | |||
T2239L | Raltegravir | MK-0518 | HIV Protease , Integrase |
Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV INFECTION. | |||
T6300 | Degrasyn | WP1130 | Apoptosis , JAK , Bcr-Abl , DUB , Autophagy |
Degrasyn (WP1130) (WP1130), a specific deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor, also inhibits Bcr/Abl, which is a JAK2 transducer (without affecting 20S proteasome) and activator of transcri... | |||
T8369 | Adagrasib | MRTX849 | Ras |
Adagrasib (MRTX849) is an orally active and selective covalent inhibitor of KRAS G12C. Adagrasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Adagrasib ... | |||
T72162 | HIV-1 integrase inhibitor 10 | ||
HIV-1 integrase inhibitor 10 is an orally active HIV-1 allosteric integrase inhibitor (ALLINI). HIV-1 integrase inhibitor 10 can inhibit viral outgrowth of the NLRepRluc virus in MT-2 cells with EC 50 values of 3-5 nM. H... | |||
T74856 | ER degrader 4 | ||
ER degrader 4 is a selective and orally active estrogen receptor degrader. ER degrader 4 has anti-tumor activity [1] . | |||
T64284 | PROTAC CDK12/13 Degrader-1 | ||
PROTAC CDK12/13 Degrader-1 (7f) is a potent and selective dual degrader of the cell cycle protein-dependent kinases CDK12 (DC50: 2.2 nM) and CDK13 (DC50: 2.1 nM). Breast cancer. | |||
T62156 | HIV-1 integrase inhibitor 9 | ||
HIV-1 integrase inhibitor 9 (compound 8a) is a potent inhibitor of HIV-1 RNase H (IC50: 12.3 μM) and has antiviral effects. | |||
T79742 | CARM1 degrader-2 | Histone Methyltransferase | |
PROTAC CARM1 degrader-2 (compound 3e), with a DC50 value of 8.8 nM, is a VHL- and proteasome-dependent degrader of co-activator associated argininemethyltransferase (CARM1). It not only promotes the degradation of CARM1 ... | |||
T79741 | CARM1 degrader-1 | Histone Methyltransferase | |
PROTAC CARM1 degrader-1 (compound 3b) serves as a highly potent degrader (DC50=8.1 nM) of the co-activator associated arginine methyltransferase (CARM1). This compound facilitates the degradation of CARM1 via the VHL-pro... | |||
T80633 | Androgen receptor degrader-1 | Androgen Receptor | |
Androgen Receptor Degrader-1 (Compound 18) is a potent agent for androgen receptor degradation, applicable in cancer research [1]. | |||
T79148 | PROTAC KRAS G12C degrader-3 | Ras | |
PROTAC KRAS G12C Degrader-3 (Comp 283) serves as a potent degrader of KRAS G12C, utilized in cancer research [1]. | |||
T79383 | ER degrader 7 | ||
ER degrader 7 (Compound 35t) is a selective degrader of both ERα and ERβ, and possesses activity as a tubulin polymerization inhibitor. It exhibits potent cell viability inhibition, with IC50 values of 0.06 μM for MCF-7,... | |||
T79161 | PROTAC PTPN2 degrader-2 TFA | Phosphatase | |
PROTAC PTPN2 degrader-2 (example 187B) TFA is a potent degrader of Protein Tyrosine Phosphatase Non-receptor Type 2 (PTPN2), with potential applications in cancer and metabolic disease research [1]. | |||
T79160 | PROTAC PTPN2 degrader-2 | Phosphatase | |
PROTAC PTPN2 degrader-2 (example 187B) is a potent agent capable of degrading PTPN2, which holds potential for research in cancer and metabolic diseases [1]. | |||
T79505 | PROTAC TG2 degrader-1 | PROTACs | |
PROTAC TG2 Degrader-1 (Compound 11) is a VHL-based PROTAC that targets tissue transglutaminase (TG2) and exhibits a binding affinity with a K D of 68.9 μM. This compound effectively decreases TG2 levels in ovarian cancer... | |||
T79067 | PROTAC BTK Degrader-3 | PROTACs | |
PROTAC BTK Degrader-3 is a potent degrader of Bruton's tyrosine kinase (BTK), exhibiting a DC50 (median degradation concentration) of 10.9 nM in Mino cells. This compound shows promise for research into B-cell malignanci... | |||
T77931 | PROTAC IRAK3 degrade-1 formic | PROTACs | |
PROTAC IRAK3 Degrade-1 (Compound 23) is a selective and potent IRAK3 degrader, demonstrating an IC50 value of 5 nM [1]. | |||
T77974 | PROTAC BCR-ABL Degrader-1 | PROTACs | |
PROTAC BCR-ABL Degrader-1 (compound PROTAC 1), featuring a 2-oxoethyl linker, promotes Bcr-Abl degradation through the ubiquitin-proteasome pathway and demonstrates antiproliferative effects on K562 cells, suggesting its... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5802 | Stearyl glycyrrhetinate | Antiviral , Antibacterial | |
Stearyl glycyrrhetinate, the stearyl ester of 18-β-glycyrrhetinic acid, has been demonstrated to improve antiviral effects, reduce inflammation and suppress allergies in the pharmaceutical and cosmetic industry. | |||
TN7026 | Acorus gramineus, ext. | Others | |
Acorus gramineus, ext is a natural product isolated from Acorus gramineus. | |||
T6520 | Grape Seed Extract | Grape Seed P.E. | Apoptosis , Others |
Grape Seed Extract (Grape Seed P.E.) is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites (BIOFLAVONOIDS and polyphenols) credited with important medicinal properties. | |||
T3884 | Neoandrographolide | Neoandrographiside | NOS , COX |
Neoandrographolide (Neoandrographiside) has potent hypolipidemic effect and protects the cardiovascular without significant liver damage.Neoandrographolide has anti-inflammatory effect, might result from inhibition of iN... | |||
TJS1748 | Methyl protogracillin | 山药 | Antifection |
Methyl protogracillin is a natural product from Dioscorea collettii var. hypoglauca with anti-cancer activity. | |||
TQ0218 | Deoxyandrographolide | 14-deoxyandrographolide | IL Receptor , TNF |
Deoxyandrographolide (14-deoxyandrographolide) potentiates NGF-induced neurite outgrowth. Deoxyandrographolide suppresses the production of proinflammatory mediators TNF-α and IL-6. | |||
TN6705 | Graveoline | 2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one,Foliosine | Autophagy |
Graveoline (2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one) is an apoptosis and autophagy inducer in skin melanoma cancer cells | |||
TN7091 | Isolugrandoside | Others | |
Isolugrandoside is from the aerial parts of Digitalis davisiana Heywood. | |||
T9218 | Andrograpanin | 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE | p38 MAPK |
Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties. | |||
T2738 | Dehydroandrographolide | NOS , Influenza Virus | |
Dehydroandrographolide is a natural compound extracted from herbal medicine Andrographis paniculata (Burm f) Nees. | |||
T1130 | Gramicidin | Gramicidinum,Gramicidine,Gramicidina | MRP , Antibacterial , Antibiotic |
A group of peptide antibiotics from BACILLUS brevis. Gramicidin (Gramicidine) C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is one of the two principal components of TYROTH... | |||
T2898 | Andrographolide | Andrographis | SARS-CoV , Influenza Virus , NF-κB , Autophagy |
Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potential antineoplastic. | |||
T8288 | 14-Deoxyandrographolide | Apoptosis , Others | |
14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release. | |||
TN1038 | Galgravin | Apoptosis | |
Galgravin has anti-inflammatory, and neuroprotective effects, it can promote neuronal survival and neurite outgrowth, protect hippocampal neurons against amyloid beta peptide (Abeta25-35)-induced cytotoxicity, and protec... | |||
TQ0185 | 14-Deoxy-11,12-didehydroandrographolide | AP10,14-dehydro Andrographolide | NF-κB |
14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation. | |||
T3667 | Kalii Dehydrographolidi Succinas | Ddhads,Dehydroandrographolide Succinate Potasium Salt | Others |
Kalii Dehydrographolidi Succinas (Dehydroandrographolide Succinate Potasium Salt) is a natural compound with anti-virus infection activity. | |||
T3774 | Gracillin | 山药 | cell cycle arrest |
Gracillin can induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells, and has the potential to be developed as an antitumor agent. Gracillin can be selected as lead compounds for the development of new d... | |||
T2S0257 | Dehydroandrographolide succinate | Others , Influenza Virus | |
Dehydroandrographolide Succinate is a traditional Chinese medicine used in the treatment of pneumonia, respiratory tract infection. | |||
T2S0250 | Pseudoprotogracillin | 山药 | Others |
Pseudoprotogracillin is a steroidal saponin extracted from Dioscoreae. | |||
T2S1749 | Protogracillin | 山药 | Others |
Protogracillin may have inhibitions on platelet aggregation (PAG) and thrombosis. | |||
TN7092 | Lugrandoside | Others | |
Lugrandoside is a novel phenylpropanoid glycoside, lugrandoside, has been isolated from the caulinary leaves of Digitalis Lutea L. and Difitalis Grandiflora Miller. | |||
T6519 | Gramine | NSC 16892,Donaxine | Adiponectin receptor , Reverse Transcriptase , Adrenergic Receptor |
Gramine (Donaxine), a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for AdipoR2 and AdipoR1, respectively. Gramine is als... | |||
T8898 | Granilin | Graniline | Others , Antibacterial , Antifungal |
Granilin (Graniline)e is a natural product. | |||
T40924 | Tellimagrandin II | Eugeniin | |
Tellimagrandin II (Eugeniin) is the initial intermediate in the 4 C 1 -glucose derived series of ellagitannins. Additionally, it possesses the ability to inhibit antibiotic resistance exhibited by drug-resistant Staphylo... | |||
TN3411 | Andrographidine C | Others | |
Andrographidine C is a natural product of Andrographis, Acanthaceae. The catalog number is TN3411 and the CAS number is 113963-39-6. Andrographidine C can be used as a reference standard. | |||
T31993 | Grayanotoxin II | G-II,Deacetylanhydroandromedotoxin,delta(sup 10 (18))-Andromedenol | |
Grayanotoxins are a group of closely related neurotoxins named after Leucothoe grayana. Extract from leaves of Ericaceae. | |||
TN5586 | 14-Deoxy-12-hydroxyandrographolide | ||
14-Deoxy-12-hydroxyandrographolide is a natural product of Andrographis, Acanthaceae. The catalog number is TN5586 and the CAS number is 219721-33-2. 14-Deoxy-12-hydroxyandrographolide can be used as a reference standard... | |||
TN3605 | Casegravol | Others | |
Casegravol shows antiproliferative activity against human gastric adenocarcinoma (MK-1), human uterus carcinoma (HeLa), and murine melanoma (B16F10) cells. | |||
TN5710 | Integracin A | ||
Integracin A is a natural product for research related to life sciences. The catalog number is TN5710 and the CAS number is 224186-03-2. | |||
TN4078 | Fragransin A2 | Others | |
Fragransin A2 is a natural product of Myristica, Myristicaceae. The catalog number is TN4078 and the CAS number is 112652-46-7. Fragransin A2 can be used as a reference standard. | |||
TN5430 | Pomegralignan | ||
Pomegralignan is a natural product for research related to life sciences. The catalog number is TN5430 and the CAS number is 1562492-32-3. | |||
T41042 | Gramicidin C | ||
Gramicidin C is a naturally occuring polypeptide antibiotic isolated from B. brevis var. G.B. | |||
T72580 | Isoandrographolide | ||
Isoandrographolide possesses cell differentiation inducing and hepatoprotective effect. Isoandrographolide inhibits NLRP3 inflammasome activation and attenuates silicosis in mice . | |||
T82562 | Dide-O-methylgrandisin | ||
Dide-O-methylgrandisin, a neolignan of the diaryltetrahydrofuran class, is referenced as compound [1]. | |||
T20217 | Grandiflorenic acid | ||
Grandiflorenic acid can reproduce the uterine responses induced by aqueous extract of zoapatle leaves. It is suggested that grandiflorenic acid may have an antifertility effect. | |||
TN4165 | Grayanotoxin I | Others | |
Grayanotoxin I is a natural product for research related to life sciences. The catalog number is TN4165 and the CAS number is 4720-09-6. | |||
TN6599 | Andrographidine A | ||
Andrographidine A is a natural product for research related to life sciences. The catalog number is TN6599 and the CAS number is 113963-37-4. | |||
TN2623 | 14-Deoxy-17-hydroxyandrographolide | Antifection | |
14-Deoxy-17-hydroxyandrographolide is a natural product of Andrographis, Acanthaceae. The catalog number is TN2623 and the CAS number is 869384-82-7. 14-Deoxy-17-hydroxyandrographolide can be used as a reference standard... | |||
TN3429 | Aphagranin A | Others | |
Aphagranin A exhibits strong antiproliferative activity against the growth of six lines of human cancer cells (MCF-7, A549, HepG2, Bel-7402, SGC-7901, and BGC-823. | |||
TN2291 | Uvarigranol B | Others | |
Uvarigranol B is a natural product | |||
TN4164 | Grandifloroside | TNF | |
Grandifloroside shows good antioxidative and potent anti-inflammatory activities, it also exhibits potent inhibitory activity against TNF-α and 5α-reductase, suggests that it might be developed as a source of potent anti... | |||
TN3412 | Andrographiside | Others | |
Andrographiside shows protective effects on hepatotoxicity induced in mice by carbon tetrachloride or tert-butylhydroperoxide (tBHP) intoxication, the effects could be due to its glucoside groups which may act as strong ... | |||
TN2463 | 14-Deoxy-11-oxoandrographolide | Others | |
14-Deoxy-11-oxoandrographolide is a natural product from Andrographis paniculata | |||
TN2602 | 12-Oxograndiflorenic acid | Others | |
12-Oxograndiflorenic acid is a natural product that can be extracted from Anemone and Porphyra and is cytotoxic to some cells. | |||
TN5585 | 14-Deoxy-11-hydroxyandrographolide | ||
14-Deoxy-11-hydroxyandrographolide shows potent cell differentiation-inducing activity towards mouse myeloid leukemia (M1) cells. | |||
TN2605 | 12alpha-Hydroxygrandiflorenic acid | Others | |
12alpha-Hydroxygrandiflorenic acid is a natural product of Wedelia, Asteraceae. The catalog number is TN2605 and the CAS number is 63768-17-2. 12alpha-Hydroxygrandiflorenic acid can be used as a reference standard. | |||
TN4163 | Grandifloric acid | Others | |
Grandifloric acid is a natural product of Siegesbeckia, Asteraceae. The catalog number is TN4163 and the CAS number is 22338-69-8. Grandifloric acid can be used as a reference standard. | |||
TN3813 | Delgrandine | Others | |
Delgrandine is a natural product of Delphinium, Ranunculaceae. The catalog number is TN3813 and the CAS number is 145237-05-4. Delgrandine can be used as a reference standard. | |||
TN5387 | Grasshopper ketone | ERK , p38 MAPK , NO Synthase , JNK | |
Grasshopper ketone, isolated from the brown alga Sargassum, is a potent inhibitor of LPS-induced NO production in RAW 264.7 cells and induces anti-inflammatory effects by inhibiting MAPK (ERK, JNK and p38) and NF-κB p65 ... | |||
T13582 | Bisandrographolide C | Others | |
Bisandrographolide C is identified from Andrographis paniculata. Bisandrographolide C activates TRPV1 and TRPV3 channels (Kds: 289 and 341 μM) and protects cardiomyocytes from hypoxia-reoxygenation injury. | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05159 | Granzyme A/GZMA Protein, Human, Recombinant (His) | Human | HEK293 |
TMPY-00817 | Granzyme B/GZMB Protein, Human, Recombinant (His) | Human | HEK293 |
Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ... | |||
TMPY-00978 | Progranulin Protein, Human, Recombinant (His) | Human | HEK293 |
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The precursor protein, progranulin, ... | |||
TMPJ-00925 | Grancalcin Protein, Human, Recombinant | Human | E. coli |
Grancalcin (GCA) is a cytoplasmic granule membrane protein that contains 4 EF-hand domains. GCA is calcium-binding protein and particularly abundant in human neutrophils. GCA is highly expressed in bone marrow, and it ca... | |||
TMPK-00673 | SG3/Secretogranin 3 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regu... | |||
TMPH-03633 | GRA2 Protein, Toxoplasma gondii, Recombinant (His & Myc) | Toxoplasma gondii | E. coli |
TMPH-03632 | GRA1 Protein, Toxoplasma gondii, Recombinant (His) | Toxoplasma gondii | E. coli |
TMPH-00070 | Major allergen Api g 1, isoallergen 2 Protein, Apium graveolens, Recombinant (His) | Apium graveolens | E. coli |
TMPH-03368 | SG3/Secretogranin 3 Protein, Rat, Recombinant (His & Myc) | Rat | E. coli |
TMPH-01412 | Granzyme B Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target pr... | |||
TMPH-03634 | GRA3 Protein, Toxoplasma gondii, Recombinant (His) | Toxoplasma gondii | E. coli |
TMPY-00818 | Granzyme H/GZMH Protein, Human, Recombinant (His) | Human | HEK293 |
Granzymes are key components of the immune response that play important roles in eliminating host cells infected by intracellular pathogens. Several granzymes are potent inducers of cell death. A total of eight granzymes... | |||
TMPJ-00770 | Granzyme B/GZMB Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an... | |||
TMPY-03994 | SG3/Secretogranin 3 Protein, Human, Recombinant (His) | Human | HEK293 |
SCG3, also known as secretogranin 3, is a member of the chromogranin/secretogranin family. Members of this family may serve as precursors for biologically active peptides. SCG3 is transported to secretory granules (SGs) ... | |||
TMPK-01122 | SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His) | Human | HEK293 |
Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regu... | |||
TMPJ-00832 | Granzyme D/GZMD Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Granzyme D is a member of the granzyme family of the serine proteases which plays a role in the induction of apoptosis. T cells, lymphohematopoietic stromal cells, and granulated metrial gland cells express granzyme D, b... | |||
TMPY-01435 | Progranulin Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The precursor protein, progranulin, ... | |||
TMPH-03159 | DODA Protein, Portulaca grandiflora, Recombinant (His & Myc & SUMO) | Portulaca grandiflora | E. coli |
Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both... | |||
TMPH-02068 | Secretogranin-1 Protein, Human, Recombinant (GST & His) | Human | E. coli |
Functions as a GC-rich promoter-specific transactivating transcription factor. | |||
TMPH-02688 | Granzyme C/GZMC Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Acts as a chaperone. | |||
TMPH-00069 | Major allergen Api g 1, isoallergen 1 Protein, Apium graveolens, Recombinant (His & SUMO) | Apium graveolens | E. coli |
TMPY-06547 | Granulysin Protein, Human, Recombinant (hFc) | Human | HEK293 |
TMPY-06567 | Granzyme K/GZMK Protein, Human, Recombinant (His) | Human | HEK293 |
TMPY-03968 | Secretogranin II Protein, Human, Recombinant (His) | Human | HEK293 |
Kit ligand, also known as Hematopoietic growth factor KL, Mast cell growth factor, Steel factor, Stem cell factor, c-Kit ligand, Kitlg and KITL, is a single-pass type I membrane protein that belongs to the SCF family. KI... | |||
TMPY-04675 | SG3/Secretogranin 3, Mouse, Recombinant (His) | Mouse | HEK293 |
SCG3, also known as secretogranin 3, is a member of the chromogranin/secretogranin family. Members of this family may serve as precursors for biologically active peptides. SCG3 is transported to secretory granules (SGs) ... | |||
TMPH-02452 | Measles virus (MeV) (strain Leningrad-16) Fusion glycoprotein F0 (Avi & His) | MeV | in vitro E. coli expression system |
TMPH-02687 | Granzyme A/GZMA Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Acts as a chaperone. | |||
TMPH-02689 | Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macro... | |||
TMPH-02069 | Secretogranin-2 Protein, Human, Recombinant (GST & His) | Human | E. coli |
Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mito... | |||
TMPH-00755 | Integrase Protein, Escherichia phage lambda, Recombinant (His) | Escherichia phage lambda | E. coli |
TMPH-03635 | GRA6 Protein, Toxoplasma gondii, Recombinant (GST) | TOV-Toxoplasma gondii | E. coli |
Cat No. | Product Name | ||
---|---|---|---|
L8110 | Reprogramming Compound Library | 1840 compounds | |
A unique collection of 1840 reprogramming signaling pathway-related bioactive small molecule compounds for high-throughput, high-content screening. |