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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2098 | A 77-01 | A77-01 | ALK , TGF-beta/Smad |
A 77-01 is a potent inhibitor of TGF-(beta) type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM. | |||
T3031 | A 83-01 | ALK5 Inhibitor IV,A8301 | ALK , TGF-beta/Smad |
A 83-01 (ALK5 Inhibitor IV) is an inhibitor of the TGF-β type I receptors ALK5, ALK4, and ALK7 (IC50=12/45/7.5 nM). A 83-01 promotes the reprogramming of mouse fibroblasts into iPSCs. A 83-01 can be used in organoid cult... | |||
T16904 | Smurf1-IN-A01 | A01 | Others |
Smurf1-IN-A01 (A01) is a ubiquitin ligase Smad ubiquitination regulatory factor-1 inhibitor (kd: 3.664 nM). It increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation. | |||
T10442 | A 83-01 sodium salt | ALK | |
A 83-01 sodium salt is a potent inhibitor of TGF-β type I receptor ALK5 kinase, ALK4 and ALK7, with IC 50 s of 12 nM, 45 nM and 7.5 nM against the ALK5, ALK4 and ALK7 induced transcription, respectively [1]. | |||
T69387 | NMO-IgG blocker A-01 | ||
NMO-IgG blocker A-01 is a idiotype-specific blocker of neuromyelitis opticaimmunoglobulin g (nmo-igg) binding to aquaporin-4 (aqp4) | |||
T4330 | CaCCinh-A01 | Chloride channel | |
CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM). | |||
T78208 | Leramistat | HMC-C-01-A,MBS2320 | Mitochondrial Metabolism |
Leramistat (HMC-C-01-A; MBS2320), a mitochondrial complex 1 inhibitor, plays a role in regulating cell and immune metabolism. It is effective in suppressing various conditions, including atopic dermatitis, autoimmune ski... | |||
T10125 | (3R,4R)-A2-32-01 | Others | |
(3R,4R)-A2-32-01 (compound 2) is a specific caseinolytic protein proteases (ClpP) inhibitor (EC50: 4.5 μM). | |||
T27988 | MDG486 | BAF IN A01,A01,MDG-486,MDG 486,BAF-IN-A01 | |
MDG486, an inhibitor of BAF, works by activating latent HIV-1. | |||
T3357 | Clascoterone | Cortexolone 17 alpha-propionate,17 alpha-propionate,CB-03-01,Cortexolone 17α-propionate | Androgen Receptor |
Clascoterone (CB-03-01) is a new topical and peripherally selective androgen antagonist. | |||
T24152 | HTH-01-091 | HTH-01091,HTH01-091,HTH 01-091,HTH 01091 | Serine/threonin kinase , Pim , MELK , DYRK , CDK , RIP kinase |
HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK and CLK2. HTH-01-091 can be used to study breast cancer. | |||
T25212 | CCCI-01 | CCCI 01,CCCI01,Centrosome Clustering Chemical Inhibitor-01 | Apoptosis |
CCCI-01(Centrosome Clustering Chemical Inhibitor-01) is a centrosome cluster inhibitor. CCCI-01 has anticancer activity, induces apoptosis, and can be used in the study of non-cross-resistant anticancer compounds that bl... | |||
T2374 | HTH-01-015 | AMPK | |
HTH-01-015 is a selective NUAK1 inhibitor (IC50=100 nM). | |||
T8330 | BIO-013077-01 | TGF-beta/Smad | |
BIO-013077-01 is a potent TGFbeta family type I receptors antagonist. | |||
T5597 | ZT-12-037-01 | Serine Protease , Ras | |
Zt-12-037-01 is a ATP competitive STK19 inhibitor(IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively). | |||
T22372 | MYF-01-37 | 1-[3-Methyl-3-[3-(trifluoromethyl)anilino]pyrrolidin-1-yl]prop-2-en-1-one | Others , YAP |
MYF-01-37 (1-[3-Methyl-3-[3-(trifluoromethyl)anilino]pyrrolidin-1-yl]prop-2-en-1-one) is a novel covalent TEAD inhibitor. | |||
T83657 | CCD Lipid01 | LP-01 | Others |
CCD Lipid01 (LP-01) is a lipid membrane that can be used to deliver biologically active agents . | |||
T15815 | LY3295668 | AK-01 | Aurora Kinase |
LY3295668 (AK-01) is a selective inhibitor of Aurora A with Kis of 0.8 nM and 1038 nM for Aurora A and B, respectively. | |||
T12400 | Peliglitazar racemate | (Rac)-Peliglitazar,(Rac)-BMS 426707-01,BMS 426707-01 racemate | PPAR |
Peliglitazar racemate(BMS 426707-01 racemate) is the racemate of Peliglitazar.Peliglitazar racemate may be used as a potential antidiabetic and anti-obesity agent. | |||
T9203 | JH-X-119-01 | IRAK | |
JH-X-119-01 is a highly potent and selective covalent inhibitor of IRAK-1. |