37 kda laminin receptor precursor (37lrp)

Expression system: E. coli
Length: 2-295, Full Length of Mature Protein
Activity: Not Tested

GPR37 (cathepsin Z) is an orphan receptor that belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors are a large protein family comprised of transmembrane receptors that sense molecules outside the cell and activate inside signal transduction pathways and, ultimately, cellular responses. They only exist in eukaryotes, including yeast, choanoflagellates, and animals. These receptors are bonded and activated by light-sensitive compounds, odors, pheromones, hormones, and neurotransmitters. These ligands vary in size from small molecules to peptides to large proteins. G protein-coupled receptors are involved in many diseases and are also the target of approximately 40% of all modern medicinal drugs. GPR37 is expressed in the brain and spinal cord, and at lower levels in the testis, placenta, and liver, but no detectable expression is observed in any other tissue. GPR37 may have a unique functional role in the central nervous system.

Influenza A H10N8 (A duck Guangdong E1 2012) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37 kDa and the accession number is I6PXD4.

CD2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is P08920.

CD8 beta Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 17.6 kDa and the accession number is P10966-1.

Expression system: HEK293 Cells
Length: 1-297, Full Length
Activity: BLI、ELISA

Expression system: HEK293 Cells
Length: 25-233, Partial
Activity: ELISA

Expression system: E. coli
Length: 37-278, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 1-280, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 37-555, Extracellular Domain
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-388, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-338, Partial
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 1-378, Full Length
Activity: Not Tested

HBP1 is a sequence-specific DNA-binding transcription factor. It is involved in many biological processes. It was reported that HBP1 binds to p16(INK4A) promoter and activates p16(INK4A) expression. We found that trichostatin A (TSA), an inhibitor of HDAC (histone deacetylase), induces p16(INK4A) expression in an HBP1-dependent manner. HBP1 activates or represses the expression of some specific genes during cell growth and differentiation. HBP1 was acetylated by p3 CBP in two regions: repression domain (K297 35 37) and P domain (K171 419). HBP1 acetylation after TSA treatment was confirmed by immunoprecipitation assay. HBP1 interacted with histone acetyltransferase p3 and CREB-binding protein (CBP) and also recruited p3 CBP to p16(INK4A) promoter. HBP1 acetylation at K419 plays an important role in HBP1-induced p16(INK4A) expression.

Expression system: E. coli
Length: 2-137, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 37-336, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 90-183, Partial
Activity: Not Tested

Expression system: E. coli
Length: 1-37, Partial
Activity: Not Tested

Expression system: E. coli
Length: 1-372, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-326, Full Length of Isoform 4
Activity: Not Tested

Expression system: HEK293 Cells
Length: 37-217, Partial
Activity: Not Tested

Expression system: P. pastoris (Yeast)
Length: 37-161, Partial
Activity: ELISA

CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia. Currently, several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are being developed and investigated in clinical trials. Given the unique role of CD37 in the biology of B cells, it seems that CD37 constitutes more than a docking point for monoclonal antibodies, and targeting this molecule may provide additional benefit to relapsed or refractory patients.

CD8 beta Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 17.6 kDa and the accession number is P10966-1.