enantiomer

Silvestrol aglycone (enantiomer) is a cyclopenta benzofuran core phenol.

ADU-S100 (MIW815) enantiomer ammonium salt is the less active enantiomer of ADU-S100, an activator of the stimulator of interferon genes (STING).

Atuveciclib S-Enantiomer (BAY-1143572 S-Enantiomer) is a potent and selective CDK9 inhibitor, inhibiting CDK9/CycT1 with an IC50 of 16 nM.

Bay 41-4109, a potent HBV inhibitor with an IC50 of 53 nM, exhibits greater activity compared to its less active enantiomer.

The S-enantiomer of BET-BAY 002, referred to as BET-BAY 002 S enantiomer, is a potent inhibitor of BET (Bromodomain and Extra-Terminal motif proteins).

Bitopertin R enantiomer (RG1678 R enantiomer) is the R-enantiomer of Bitopertin, a noncompetitive glycine reuptake inhibitor that inhibits glycine uptake at human GlyT1 (IC50: 25 nM).

Sofosbuvir's enantiomer, a variant of the prescription medication Sofosbuvir used for chronic hepatitis C treatment, currently lacks reported biological activity.

Gepotidacin S enantiomer is an S enantionmer of gepotidacin.

GLPG0492 R enantiomer is the R enantiomer of GLPG-0492, a novel selective androgen receptor modulator (SARMs).

IACS-8968 R-enantiomer is the R-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO).

IACS-8968 S-enantiomer is the S-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO).

Niraparib R-enantiomer (MK 4827 R-enantiomer) is an inhibitor of PARP1(IC50 of 2.4 nM).

MK-7246 S enantiomer is a potent and selective CRTH2 antagonist.

Necrostatin 2 (S enantiomer) is the S enantiomer of Necrostatin 2.

RSV604 R enantiomer is the R-enantiomer of RSV604, a replication inhibitor of respiratory syncytial virus (RSV).

SAR405 (R enantiomer) is the less active form of SAR405, an inhibitor of PIK3C3/Vps34.

Tenalisib R Enantiomer is an R enantiomer of Tenalisib .

Veledimex S enantiomer is the S enantiomer of veledimex. Veledimex is an oral activator ligand for a proprietary gene therapy promoter system and CYP3A4/5 inhibitor.

Talarozole R enantiomer is a potent and selective inhibitor of cytochrome P450 26-mediated degradation of endogenous all-trans retinoic acid.

Selisistat R-enantiomer (EX-527 (R-enantiomer)) is a R-enantiomer of Selisistat (T6111) with much less activity than Selisistat (IC50 of SIRT1 > 100 μM).

(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1, a BET bromodomain inhibitor, which acts on BRD4(1/2) with IC50 values of 77 nM and 33 nM in a cell-free assay.

(S)-PNU-282987 is the absolute stereochemistry form of PNU-282987. PNU 282987, a potent agonist of α7-containing neuronal nicotinic acetylcholine receptors (nAChRs) with Ki of 26 nM for the rat receptor, has negligible activity against α1β1γδ and α3β4 nAC

THK5351 R enantiomer is an R enantiomer of THK5351.

GSK4418959 enantiomer is the enantiomer of GSK4418959. GSK4418959 (IDE275) is a non-covalent, reversible, selective helicase inhibitor of WRN with oral bioavailability. It competitively inhibits ATPase and DNA unwinding functions in an ATP-dependent manner. GSK4418959 is utilized in the study of microsatellite instability-high (MSI-H) cancer.