tpo

Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platelet production.

4"-O-Glucosylvitexin (glucosylvitexin) inhibits TPO activity.

Lusutrombopag (Mulpleta) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery.

TPO-L is a photoinitiator used in 3D printing resins, facilitating two-photon induced polymerization. The two-photon absorption cross-section spectrum of Lucirin TPO-L exhibits a peak of 1.2 GM at 610 nm. Although the two-photon absorption cross-section is relatively small, Lucirin TPO-L demonstrates a high polymerization quantum yield.

TPO agonist 1 (TPO mimetic) is an effective thrombopoietin (TPO) agonist that promotes platelet and megakaryocyte production, suitable for thrombocytopenia research.

2.4.6-Trimethylbenzoylethoxyphenylphosphine (Standard) is a reference standard of 2.4.6-Trimethylbenzoylethoxyphenylphosphine intended for quantitative analysis, quality control, and related biochemical research applications.

Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet thrombopoietin receptor (TPO-R or CD110).

Eltrombopag Olamine (Eltrombopag diethanolamine salt) is an orally active small-molecule, nonpeptide thrombopoietin receptor agonist that stimulates megakaryopoiesis. It binds to and activates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), promoting the proliferation and differentiation of megakaryocytic cells and enhancing platelet production.

TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor with Kd values of 134 nM for CBP and 5.02 μM for BRD4.

(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.

NTPO trisodium induces DNA damage and fragmentation, activating ATR-mediated cell cycle checkpoints. Its DNA damaging effects are mitigated by base excision repair (BER) but not by nucleotide excision repair (NER) [1].

Anti-MPL/TPOR/CD110 Antibody (TA136) is a humanized antibody targeting MPL/TPOR/CD110, suitable for use in related research within the life sciences field.

Pemirolast Potassium is the potassium salt form of pemirolast, a pyrimidinone derivative with antiallergic property. Pemirolast potassium (TWT-8152) exerts its action by blocking the antigen-mediated calcium ion influx into mast cells.

Molybdenum disulfide (Moly Powder B) is a novel nanomaterial that can be used to synthesize nanoprobes.

Cyclothiazide is a benzothiadiazide that acts as a potentiator of AMPA receptorsthat potently inhibits AMPA receptor desensitization, positively modulating its response to glutamic acid (EC50 = 3.8 M).

Hoet-PO is a hydroxymethylglutaryl-CoA reductase inhibitor.

Selnoflast (potassium) (example 6), is an NLRP3 inhibitor.

MAT-POS-e194df51-1 is an orally active, non-covalent, non-peptide inhibitor of the SARS-CoV-2 main protease (M^pro) with an IC_50 of 37 nM. It exhibits cytotoxicity, showing EC_50 values of 64 nM in A549-ACE2-TMPRSS2 cells and 126 nM in HeLa-ACE2 cells [1].

Meteneprost (U 46785) potassium acts as a cervical dilator by stimulating uterine contractions and widening the cervical canal.

E. coli Extract Polar is a polar lipid extract from Escherichia coli, consisting of phosphatidylethanolamine, phosphatidylglycerol, and cardiolipin, useful for reconstituting membrane proteins.

Rosa roxburghii Tratt polysaccharides are natural products that can be used in research related to the life sciences.

Acid Phosphatase (ACP), Sweet Potato (Non-prostatic acid phosphatase, ACP, Orthophosphoric-monoester phosphohydrolase acid optimum, Acid Phosphatase, AcPase, Apase) is a biological material or organic compound suitable for life sciences research.

Non-ProstaticAcid Phosphatase, Sweet Potato (EC 3.1.3.2) is a phosphatase enzyme that facilitates the release of attached phosphate groups from other molecules during digestion. This acid phosphatase is stored within lysosomes and becomes active when lysosomes fuse with acidified endosomes, optimizing its function in an acidic pH environment.

β-Amylase, originating from Sweet potato (EC 3.2.1.2), hydrolyzes α-(1,4) glucosidic bonds in polysaccharides composed of three or more D-glucopyranose units, each linked by α-(1,4) connections.