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Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet aggregation and improves blood flow by increasing erythrocyte and leukocyte flexibility.

Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively. Aleglitazar can be used for the research of type II diabetes.

Isopulegol has antioxidant, and neuroactive properties. It also has gastroprotective effects induced by isopulegol appear to be mediated, at least in part, by endogenous prostaglandins, K+ATP channel opening and antioxidant proprieties related to GSH incr

Cyclogalegenin (Astramembrangenin) is able to elongate telomeres, resulting in increased lifespan of the animals.

1. Pulegone ((+)-Pulegone) has cytotoxicity followed by regenerative cell proliferation is the MOA for Pulegone-induced urothelial tumors in female rats. 2. Pulegone induces a verapamil-sensitive psychostimulant effect that appears to independ on the opening of L-type calcium channels. 3. Pulegone has negative reinforcing properties and seems to possess anxiolytic-like actions unrelated to the benzodiazepine site of the γ-aminobutyric acid type A (GABAA) receptor.

(S)-(-)-Pulegone is a useful organic compound for research related to life sciences and the catalog number is T125013.

(-)Isopulegone is a useful organic compound for research related to life sciences and the catalog number is T125548.

Galegine hemisulfate, a guanidine derivative, aids in weight reduction in mice. It activates AMPK in 3T3-L1 adipocytes, L6 myotubes, H4IIE rat hepatoma cells, and HEK293 human renal cell lines. Galegine hemisulfate also exhibits antibacterial activity, with a minimum inhibitory concentration of 4 mg/L against Staphylococcus aureus strains.

(-)-Pulegone is a biologically active compound that can be utilized for life science research applications.

Legubicin (Doxorubicin-LNAA-Boc) is a conjugate of Doxorubicin linked with a peptide connector hydrolyzable by Legumain. Upon activation by Legumain, Legubicin releases leucine-Doxorubicin, potentially minimizing damage to normal tissues. It inhibits tumor cell growth and reduces DNA binding ability in cells lacking legumain expression. In mice with CT26 tumors, Legubicin completely suppresses tumor growth, making it useful for colon cancer (CRC) research.

TachypleginA is a parasite motility and invasion inhibitor.

TachypleginA-2 is a parasite motility and invasion inhibitor.

Legumin is a herbicide, which is a mixture of Embutone and Tropotox.

Lycophlegmarine is a bioactive chemical.

Lycophlegmine is a bioactive chemical.

Galegine hydrochloride, a guanidine derivative derived from G. officinalis, plays a role in inducing weight loss in mice and has contributed to the development of biguanides, including metformin and phenformin. This compound stimulates AMPK activation in 3T3-L1 adipocytes, L6 myotubes, H4IIE rat hepatoma, and HEK293 human kidney cell lines. Additionally, galegine hydrochloride exhibits antibacterial properties, particularly demonstrating a minimum inhibitory concentration of 4 mg/L against Staphylococcus aureus strains[1][2].

Legumain inhibitor 1 is a highly potent and specific Legumain inhibitor with potential anticancer activity for cancer research.

Selegiline hydrochloride is a selective, reversible inhibitor of MAO-B (Ki = 0.091 μM) over MAO-A (Ki = 9.06 μM). Monoamine oxidase (MAO) inhibitors have utility in ameliorating a variety of neurological conditions, including depression.

3-Indoleglyoxylic acid modulates the mitochondrial ROS-mediated IL-17/CXCL10/TNF-α signaling pathway, protecting against bisphenol-induced intestinal barrier dysfunction.

Peceleganan (PL-5), a synthetic hybrid peptide, combines cecropin A (1-10) and melittin B (3-18) sequences to form a (10+16)-peptide analogue with antimicrobial properties. This compound effectively inhibits wound infections [1].

Peceleganan acetate (PL-5), a synthetic hybrid analogue combining segments of cecropin A (1-10) and melittin B (3-18) to form a (10+16)-peptide, demonstrates antimicrobial properties. It is specifically effective in inhibiting wound infections [1].

Galegenimab (RG 6147) is an antigen-binding fragment (Fab) targeting HtrA1, capable of blocking proteolytic cleavage of biglycan (an HtrA1 substrate), suitable for age-related macular degeneration (AMD) research.

(+)-Isopulegol is a monoterpenoid from Mentha canadensis L.

Elegrobart is an immunoglobulin G1-κ monoclonal antibody that targets the human insulin-like growth factor 1 receptor (IGF1R). It shows potential for research into diseases linked to abnormal IGF1R signaling, particularly thyroid eye disease.