enhancer

Laurocapram (N-Lauryl caprolactam) is a percutaneous enhancer. Upon application to the skin, laurocapram interacts with lipids in the stratum corneum and may enhance the ability of the skin to absorb a hydrophilic chemical.

Taraxerone has allelopathic and antifungal effects.Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration with the concentration dependent manner.

Signal enhancer for use in western blotting, dot blotting and ELISA

2-NP is a STAT1 enhancer.

TAK-137 is an AMPA receptor enhancer with antidepressant effects. TAK-137 has the ability to improve cognition and could be used to study schizophrenia.

SIB 1553A is an orally available and selective agonist of nicotinic acetylcholine receptors (nAChRs), which are subtype-selective ligands for nicotinic acetylcholine receptors.SIB-1553A is a cognitive enhancer that may be used in the study of neurodegenerative-related diseases such as Alzheimer's disease.

K-111 (BM-170744) is an orally available peroxisome proliferator-activated receptor (PPAR)-alpha agonist and insulin enhancer for the study of obesity-type diabetes mellitus and the metabolic syndrome.

ZLD1039 is a potent, orally bioavailable EZH2 (Enhancer of Zeste Homolog 2) inhibitor with high selectivity. It demonstrates strong, concentration-dependent inhibition of both wild-type and mutant (Y641F and A677G) PRC2 (Polycomb Repressive Complex 2) enzymatic activities, exhibiting IC50 values of 5.6, 15, and 4.0 nM, respectively. Additionally, ZLD1039 effectively suppresses breast tumor growth and metastasis.

BMY-21502 is a potential cognitive enhancer that shows anti-hypoxia effects in the KCN-hypoxia model, delays the decay of hippocampal synaptic enhancement in vitro, and can be used to study Alzheimer's disease.

BRD56491 is a small molecule ROS enhancer and a bioprobe for the detection of cancer.

NRX-1532 is a small molecule that acts as an enhancer of the β-catenin:β-TrCP interaction.

NRX-2663 enhances the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP and increases the binding affinity of β-catenin to β-TrCP (Kd: 54.8 nM, EC50: 22.9 nM).

NRX-103094 is a potent enhancer of the interaction between β-catenin and the homologous E3 ligase SCFβ-TrCP, increasing the affinity of pSer33 Ser37 β-catenin for β-TrCP with an EC50 of 62 nM and a Kd of 0.6 nM.

NRX-252114 (NRX252114) induces degradation of mutant β-catenin NRX-252114 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP, and is able to enhance the binding of pSer33 S37A β-catenin to β-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. Kd is 0.4 nM.

NRX-103095 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP and enhances the affinity of pSer33 Ser37 β-catenin for β-TrCP with an EC50 of 163 nM.

LUF6096 (CF-602) is a potent allosteric enhancer of the adenosine A3 receptor, exhibiting the capability to enhance agonist binding allosterically while demonstrating low orthosteric affinity across adenosine receptors. It displays protective effects in myocardial ischemia reperfusion injury.

NRX-252262 is a potent enhancer of the interaction between β-Catenin and its cognate E3 ligase, SCFβ-TrCP, inducing mutant β-Catenin degradation (EC50: 3.8 nM).

4-(Imidazol-1-yl)phenol is a potent signal enhancer in horseradish peroxidase (HRP)–luminol chemiluminescence (CL) immunoassays [1].

Polyethylene glycol 12-hydroxystearate (Solutol HS-15) is a permeability enhancer.

PTZ-343 is a potent enhancer of Luminol, acting as an electron transfer mediator. It reacts with HRP-II to release HRP and a PTZ-343 radical, which then oxidizes luminol anions to induce light emission.

Neotame (HSDB 7965) is a white-colored, dipeptide methyl ester, which is found to be a highly potent and non-nutritive sweetener or flavour enhancer and hence finds applications in a variety of foods.

N-Methylsarcosine (Dimethylglycine) is used as an athletic performance enhancer and immunostimulant. It is also used in the treatment of autism, epilepsy and mitochondrial disease. It is also employed as a biomarker of protein degradation in chronic obstructive lung disease (COPD) patients. Further, it is used as a substrate to identify, differentiate and characterize amino acid methyltransferase. It plays an important role in the development of glycine-based ionic liquids and emulsifiers.

CAPS (N-Cyclohexyl-3-aminopropanesulfonic acid) is a surfactant that acts as a chemiluminescence enhancer and can be used in the development of deep-sea in situ analyzers.

Coluracetam (MKC-231)(MKC-231) is a Choline Uptake Enhancer.