Inhibitory checkpoint molecules play an important role in the maintenance of immune homeostasis: their expression on effector T cells ensures the proper contraction of effector T cell responses; their expression on regulatory T (Treg) cells promotes the suppressive function of Tregs. Blockade of inhibitory immune checkpoint molecules has proven to enhance immune responses to various cancers and exhibit remarkable clinical efficacy in cancer treatment.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPJ-00063 | CD160 Protein, Human, Recombinant (hFc)
CD160 Protein, Human, Recombinant (hFc)
|
Human | Human Cells |
CD160 antigen is a Lipid-anchor that exists as a disulfide-linked homomultimer. CD160 contains one Ig-like V-type domain. The human CD160 precursor is a cysteine... | |||
TMPJ-00107 | CTLA-4 Protein, Human, Recombinant (Flag)
CTLA-4 Protein, Human, Recombinant (Flag)
|
Human | Human Cells |
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. Human or mouse CTLA4 cDNA enc... | |||
TMPJ-00108 | CTLA-4 Protein, Human, Recombinant (GST)
CTLA-4 Protein, Human, Recombinant (GST)
|
Human | Human Cells |
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. Human or mouse CTLA4 cDNA enc... | |||
TMPJ-00129 | BTLA Protein, Human, Recombinant (His)
BTLA Protein, Human, Recombinant (His)
|
Human | Human Cells |
B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induc... | |||
TMPJ-00173 | TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-191, His)
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-191, His)
|
Mouse | Human Cells |
T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of... | |||
TMPJ-00174 | TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-193, His)
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-193, His)
|
Mouse | Human Cells |
T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of... | |||
TMPJ-00175 | B7-H4 Protein, Rhesus macaque, Recombinant (hFc)
B7-H4 Protein, Rhesus macaque, Recombinant (hFc)
|
Rhesus macaque | Human Cells |
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas,... | |||
TMPJ-00176 | B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | Human Cells |
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins. Mature human B7-H4 consists of a 235 amino acid (aa) extracellula... | |||
TMPJ-00179 | LAIR1 Protein, Human, Recombinant (aa 22-163, His & Avi), Biotinylated
LAIR1 Protein, Human, Recombinant (aa 22-163, His & Avi), Biotinylated
|
Human | Human Cells |
Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) is a single-pass type I membrane protein. LAIR1 expressed on the majority of peripheral mononuclear c... | |||
TMPJ-00181 | PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated
PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | Human Cells |
Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-... | |||
TMPJ-00182 | PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | Human Cells |
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin ... | |||
TMPJ-00183 | PD-L1 Protein, Human, Recombinant (Flag)
PD-L1 Protein, Human, Recombinant (Flag)
|
Human | Human Cells |
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin ... | |||
TMPJ-00187 | CD300A Protein, Human, Recombinant (hFc & His)
CD300A Protein, Human, Recombinant (hFc & His)
|
Human | Human Cells |
CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of... | |||
TMPJ-00189 | TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (His)
TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | Human Cells |
T cell immunoglobulin and mucin domain 3 is a member of the TIM family of immune regulating molecules. Mature cynomolgus TIM3 consists of a 182 amino acid (aa)ex... | |||
TMPJ-00195 | FGL1 Protein, Cynomolgus, Recombinant (Avi & His), Biotinylated
FGL1 Protein, Cynomolgus, Recombinant (Avi & His), Biotinylated
|
Cynomolgus | Human Cells |
Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfami... | |||
TMPJ-00197 | FGL1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
FGL1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | Human Cells |
Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfami... | |||
TMPJ-00198 | FGL1 Protein, Human, Recombinant (Avi & His), Biotinylated
FGL1 Protein, Human, Recombinant (Avi & His), Biotinylated
|
Human | Human Cells |
Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfami... | |||
TMPJ-00203 | Galectin-9 Protein, Human, Recombinant (GST)
Galectin-9 Protein, Human, Recombinant (GST)
|
Human | E. coli |
Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galect... | |||
TMPJ-00208 | CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | Human Cells |
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 b... | |||
TMPJ-00209 | CD47 Protein, Human, Recombinant (Avi & His), Biotinylated
CD47 Protein, Human, Recombinant (Avi & His), Biotinylated
|
Human | Human Cells |
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 b... |