dimer

N,N'-Diacetyl-L-cystine (DiNAC) is the disulphide dimer of N-acetylcysteine with immunomodulating properties. N,N'-diacetyl-L-cystine also has antiatherosclerotic effects in Watanabe-heritable hyperlipidemic rabbit (WHHL) rabbits. N,N'-diacetyl-L-cystine is also an effective and orally active modulator of contact sensitivity delayed-type hypersensitivity reactions in rodents.

Ibrutinib dimer is an impurity of Ibrutinib. IIbrutinib dimer is a Dimer of Ibrutinib. Ibrutinib is an irreversible Btk inhibitor (IC50: 0.5 nM).

Elgonica dimer A is a useful organic compound for research related to life sciences and the catalog number is T126051.

ddC-AZT dimer is a biochemical.

Ethoxyquin dimer is an antioxidant and metabolite of ethoxyquin .1 It prevents oxidation of polyunsaturated fatty acids in fish meal and fish oil. Dietary administration of ethoxyquin dimer (0.1, 0.3, and 0.5% w/w) induces microvesicular steatosis and hepatocyte necrosis, as well as increases liver levels of oxidized glutathione and total lipids in mice.2

MSA-2 dimer, a selective and orally active non-nucleotide STING agonist with a dissociation constant (Kd) of 145 μM, demonstrates prolonged antitumor and immunogenic activity. It non-covalently binds to STING as a dimer, showing greater permeability compared to cyclic dinucleotide[1].

Terazosin dimer impurity dihydrochloride, a dimeric form of Terazosin, is a chemical impurity found in Terazosin. Terazosin itself is a derivative of quinazoline and acts as a competitive and orally active α1-adrenoceptor antagonist[1].

Oxytocin parallel dimer is a homo peptide dimer connected by a disulfide bridge.

Oxytocin antiparallel dimer is a disulfide-bridged homopeptide dimer.

Tricarbonyldichlororuthenium(II) dimer, a pharmacological CO donor, prevents ischemia/reperfusion (I/R)-induced oxidative damage to the gastric mucosa by enhancing gastric blood flow (GBF) and reducing DNA oxidation and systemic inflammatory response.

BG dimer is a molecular dimer [organic luminogen] with aggregation-induced emission (AIE).

(2'-Amino-1,1'-biphenyl-2-yl)methanesulfonatopalladium(II) dimer is a useful organic compound for research related to life sciences and the catalog number is T66783.

(2'-Methylamino-1,1'-biphenyl-2-yl)methanesulfonatopalladium(II) dimer is a useful organic compound for research related to life sciences and the catalog number is T67263.

Tolterodine Dimer is a derivative of Tolterodine -- a muscarinic receptor antagonist that is used to treat patients with overactive bladder.

Nevirapine dimer is a non-nucleoside reverse transcriptase inhibitor (NNRTI).

Fluticasone dimer impurity, a dimeric derivative of Fluticasone Propionate, is a corticosteroid recognized for its high receptor affinity and potent topical activity.

N-Acetyldopamine dimer-2 (compound 2), an N-acetyldopamine dimer derived from the yellow powder of Periostracum Cicadae, exhibits antioxidant and anti-inflammatory properties by inhibiting oxidized low-density lipoprotein (LDL) oxidation, reducing reactive oxygen species (ROS) generation and nitric oxide (NO) production, and suppressing NF-κB activity [1].

Oxytocin Parallel Dimer TFA, a disulfide-bridged homopeptide dimer, exhibits both oxytocin and vasopressin-like activity while being less toxic than oxytocin [1] [2].

Vasopressin Dimer (parallel) TFA, a parallel dimer of Vasopressin, has the capability to activate four G protein-coupled receptors—namely, V1aR, V1bR, V2R, and OTR [1].

Vasopressin Dimer (anti-parallel) TFA, an anti-parallel dimer form of vasopressin, has the capability to activate four G protein-coupled receptors: V1aR, V1bR, V2R, and OTR [1].

Oxytocin antiparallel dimer TFA is a homo peptide dimer connected by a disulfide bridge, exhibiting activities similar to oxytocin and vasopressin but with reduced toxicity [1] [2].

Naphthyridine carbamate dimer (NCD) acts as a molecular glue for DNA, facilitating specific structural alterations within targeted functional DNA sequences to modulate their activity [1].

N-Acetyldopamine dimer-3 (Compound 11), a naturally occurring chemical, is present in the species Aspongopus chinensis [1].

PBD dimer-2 (compound 2c), a C8-linked pyrrolobenzodiazepine dimer, has the capability to span an extra base pair and cross-link the 5′-Pu-GA(T A)TC-Py sequence. It serves as a potential payload for antibody–agent conjugates (ADCs) and is under research for cancer treatments [1] [2].