Opioid Receptor

Opioid receptors belong to the large superfamily of seven transmembrane-spanning (7TM) G protein-coupled receptors (GPCRs). As a class, GPCRs are of fundamental physiological importance mediating the actions of the majority of known neurotransmitters and hormones.

Cat. No.	Product name	CAS No.	Purity
T11198	Endomorphin 2 TFA	1276124-00-5	98%
Endomorphin 2 TFA, displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM. a high affinity, highly selective agonist of the...
T12241	Norbinaltorphimine dihydrochloride	113158-34-2	98%
Norbinaltorphimine dihydrochloride is a potent and selective antagonist of κ opioid receptor.
T11478L	GSK1521498 free base	1007573-18-3	98%
GSK1521498 free base is a potent and selective antagonist of the μ-opioid receptor. GSK1521498 free base also has the potential for disorders of compulsive consu...
T7404	Dermorphin	77614-16-5	98%
Dermorphin is agonist of μ-opioid receptor (MOR) agonist.
T15165	DPI-3290	182417-73-8	98%
DPI-3290 is a specific agonist of opioid receptors (Ki: 0.18 nM, 0.46 nM, and 0.62 nM for δ-, μ-, and κ-opioid receptors, respectively) with potent antinocicepti...
T12314	Opioid receptor modulator 1	77514-44-4	98%
Opioid receptor modulator 1 is a modulator of opioid receptor.
T13438	(R,S)-Ivosidenib	2070009-31-1	98%
(R,S)-Ivosidenib is the less active enantiomer of Ivosidenib .
T7173	[Leu5]-Enkephalin	58822-25-6	98%
[Leu5]-Enkephalin is an endogenous neuropeptide involved in nociception and an agonist of δ-opioid and µ-opioid receptors (Kis = 4.0 and 3.4 nM, respectively)
TN3367	Akuammidine	639-36-1	98%
Akuammidine shows anti-inflammatory and anti-asthmatic properties, it has opioid analgesic activity, it shows a preference for mu-opioid binding sites with Ki va...
T4633	Asimadoline	153205-46-0	98%
Asimadoline is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany. Asimadoline was originally developed to treat...
TP1793	Nociceptin (1-13), amide	178064-02-3	98%
Nociceptin (1-13), amide is a potent ORL1 (OP4) receptor agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain memb...
T7306	Valorphin	144313-54-2	98%
Valorphin has opioid analgesic activity, binds to rat mu-opioid receptor, with an IC50 of 14 nM.
T7576	β-Casomorphin, bovine	72122-62-4	98%
β-Casomorphin, bovine(2TFA) is an opioid peptide isolated from casein peptone
TN3368	Akuammigine	642-17-1	98%
Akuammigine has in vitro antimalarial activity. Akuammigine competitively antagonizes the effect of noradrenaline on postsynaptic alpha-adrenoceptors, yielding p...
TP2036	DPDPE	88373-73-3	98%
DPDPE is selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro (EC50 = 5.2 nM), and is antinoc...
T7567	Adrenorphin	88377-68-8	98%
Adrenorphin(3TFA) is an agonist of μ-opioid receptor(Ki :12 nM).
TN5017	Sideritoflavone	70360-12-2	98%
Sideritoflavone has anti-inflammatory effect, it is a selective inhibitor of lipoxygenase activity in vitro.
TP1367L	[D-Ala2]leucine-enkephalin acetate	TP1367L	98%
[D-Ala2]Leucine enkephalin acetate is a delta opioid agonist used to study the signaling pathway of delta opioid receptors.
T13419	ROCK-IN-1	934387-35-6	98%
ROCK-IN-1 is a potent ROCK inhibitor(IC50 of 1.2 nM , ROCK2).
T11478	GSK1521498 free base (hydrochloride)	1007578-24-6	98%
GSK1521498 free base (hydrochloride) is a selective antagonist of the μ-opioid receptor (MOR). It is being used for the treatment of disorders of compulsive cons...

Cat. No.

Product name

CAS No.

Purity

Chemical Structure

T11198

Endomorphin 2 TFA

1276124-00-5

98%

Endomorphin 2 TFA, displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM. a high affinity, highly selective agonist of the...

T12241

Norbinaltorphimine dihydrochloride

113158-34-2

98%

Norbinaltorphimine dihydrochloride is a potent and selective antagonist of κ opioid receptor.

T11478L

GSK1521498 free base

1007573-18-3

98%

GSK1521498 free base is a potent and selective antagonist of the μ-opioid receptor. GSK1521498 free base also has the potential for disorders of compulsive consu...

T7404

Dermorphin

77614-16-5

98%

Dermorphin is agonist of μ-opioid receptor (MOR) agonist.

T15165

DPI-3290

182417-73-8

98%

DPI-3290 is a specific agonist of opioid receptors (Ki: 0.18 nM, 0.46 nM, and 0.62 nM for δ-, μ-, and κ-opioid receptors, respectively) with potent antinocicepti...

T12314

Opioid receptor modulator 1

77514-44-4

98%

Opioid receptor modulator 1 is a modulator of opioid receptor.

T13438

(R,S)-Ivosidenib

2070009-31-1

98%

(R,S)-Ivosidenib is the less active enantiomer of Ivosidenib .

T7173

[Leu5]-Enkephalin

58822-25-6

98%

[Leu5]-Enkephalin is an endogenous neuropeptide involved in nociception and an agonist of δ-opioid and µ-opioid receptors (Kis = 4.0 and 3.4 nM, respectively)

TN3367

Akuammidine

639-36-1

98%

Akuammidine shows anti-inflammatory and anti-asthmatic properties, it has opioid analgesic activity, it shows a preference for mu-opioid binding sites with Ki va...

T4633

Asimadoline

153205-46-0

98%

Asimadoline is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany. Asimadoline was originally developed to treat...

TP1793

Nociceptin (1-13), amide

178064-02-3

98%

Nociceptin (1-13), amide is a potent ORL1 (OP4) receptor agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain memb...

T7306

Valorphin

144313-54-2

98%

Valorphin has opioid analgesic activity, binds to rat mu-opioid receptor, with an IC50 of 14 nM.

T7576

β-Casomorphin, bovine

72122-62-4

98%

β-Casomorphin, bovine(2TFA) is an opioid peptide isolated from casein peptone

TN3368

Akuammigine

642-17-1

98%

Akuammigine has in vitro antimalarial activity. Akuammigine competitively antagonizes the effect of noradrenaline on postsynaptic alpha-adrenoceptors, yielding p...

TP2036

DPDPE

88373-73-3

98%

DPDPE is selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro (EC50 = 5.2 nM), and is antinoc...

T7567

Adrenorphin

88377-68-8

98%

Adrenorphin(3TFA) is an agonist of μ-opioid receptor(Ki :12 nM).

TN5017

Sideritoflavone

70360-12-2

98%

Sideritoflavone has anti-inflammatory effect, it is a selective inhibitor of lipoxygenase activity in vitro.

TP1367L

[D-Ala2]leucine-enkephalin acetate

TP1367L

98%

[D-Ala2]Leucine enkephalin acetate is a delta opioid agonist used to study the signaling pathway of delta opioid receptors.

T13419

ROCK-IN-1

934387-35-6

98%

ROCK-IN-1 is a potent ROCK inhibitor(IC50 of 1.2 nM , ROCK2).

T11478

GSK1521498 free base (hydrochloride)

1007578-24-6

98%

GSK1521498 free base (hydrochloride) is a selective antagonist of the μ-opioid receptor (MOR). It is being used for the treatment of disorders of compulsive cons...