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Search Results for " p65 "

35

Compounds

27

Natural Products

6

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
TP1608 PTD-p65-P1 Peptide
PTD-p65-P1 Peptide, a selective inhibitor of the nuclear transcription factor NF-kappaB, consists of a conjugation between a membrane-translocating peptide derived from antennapedia (PTD) and p65-P1. This composition eff...
TP1395 PTD-p65-P1 Peptide TFA
Ptd-p65-p1 Peptide TFA is a nuclear transcription factor nf-kappab inhibitor, consisting of a membrane transport Peptide sequence derived from antennapedia linked to p65-p1, selectively inhibiting nf-kappab activity indu...
T8494 NS-3-008 hydrochloride NS-3-008 HCl Others
NS-3-008 hydrochloride (NS-3-008 HCl) is a transcriptional G0/G1 switch 2 (G0s2) inhibitor( IC50 of 2.25 μM).
T6761 Ossirene AS101 IL Receptor , Caspase , Interleukin
Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
TD0099 Malachite green oxalate Apoptosis , Others , IκB/IKK , NF-κB
Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.
T82701 CMV pp65(13-27)
CMV pp65(13-27) is a bioactive peptide derived from the 65k lower matrix phosphoprotein of the human cytomegalovirus, specifically comprising amino acid residues 13 to 27. It includes a nine-amino-acid sequence (LGPISGHV...
T25450 GGTI 2147 GGTI2147,Geranylgeranyl transferase inhibitor-2147,GGTI-2147 NF-κB , Rho
GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.
T11598 IAXO-102 TLR
IAXO-102 is a TLR4 antagonist that negatively regulates TLR4 signaling. It inhibits MAPK and p65 NF-κB phosphorylation and expression of TLR4 dependent proinflammatory protein. IAXO-102 also prevents experimental abdomin...
T6661 SC75741 Influenza Virus , NF-κB
SC75741 is a potent P65 inhibitor with IC50 of 200 nM
T22021 ACHP IKK-2 Inhibitor VIII IκB/IKK
ACHP (IKK-2 Inhibitor VIII) is a novel selective and potent IKK inhibitor with inhibitory effects on IKK-α and IKK-β. ACHP has anti-HIV-1 activity and inhibits HIV-1 long terminal repeat (LTR)-driven gene expression thro...
T11886 LTβR-IN-1 Others , NF-κB , LTR
LTβR-IN-1 is a potent and selective lymphin β receptor (LTβR) inhibitor. LTβR-IN-1 has a selective inhibitory effect on the nuclear translocation of p52 of TNF12A, and has no obvious effect on the nuclear translocation o...
T6454 CORM-3 CORM3 Others , NF-κB , NOD-like Receptor (NLR)
CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.
T1930 JSH-23 NF-κB
JSH-23, an NF-κB inhibitor(IC50= 7.1 μM), suppresses the transcriptional activity.
T63107 Anti-inflammatory agent 6
Anti-inflammatory agent 6 exhibits anti-inflammatory potential by blocking the phosphorylation of Iκb kinase α/β (IKKα/β), IκBα and nuclear factor kB p65 (NF-κb p65), which are key controllers of inflammation.
T26226 SRTCX1002 SRTCX 1002,SRTCX-1002
SRTCX1002 is a SIRT1 Activator Suppressing Inflammatory Responses through Promotion of p65 Deacetylation and NF-κB Activity inhibitor.
T27708 K-14585
K-14585 is a proteinase-activated receptor 2 antagonist. K-14585 inhibited PAR(2)-mediated p65 NFkappaB phosphorylation and NFkappaB-DNA binding. K-14585 inhibited SLIGKV-stimulated IL-8 production, but given alone incre...
T28853 SRTCX1003 SRTCX-1003,SRTCX 1003
SRTCX1003, a SIRT1 activator, suppresses inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB activity.
T28749 SEMBL
SEMBL, a novel inhibitor of DNA binding of NF-kappaB component p65 in vitro, inhibits NF-kappaB and cellular invasion in ovarian carcinoma ES-2 cells.
T83047 Anti-inflammatory agent 65 STING
Anti-inflammatory agent 65 (compound 29), a Hederagonic acid derivative, exhibits potent activity by inhibiting nitric oxide (NO) release, nuclear translocation of IRF3 and p65, and disrupting the STING/IRF3/NF-κB signal...
T78846 EP12 Apoptosis
EP12, a c-Myc inhibitor and G4 stabilizer, induces apoptosis and DNA damage in multiple myeloma cells while obstructing P65/P50 nuclear translocation by disrupting the NF-κB signaling pathway, effectively inhibiting mult...
T83052 Anti-inflammatory agent 60 NF-κB
Anti-inflammatory agent 60 (compound 21) inhibits nitric oxide production, presenting an IC50 of 12.95 μM, and reduces iNOS, phosphorylated p65, and β-catenin expression in a concentration-dependent manner [1].
T64018 Anti-inflammatory agent 23
Anti-inflammatory agent 23 is an anti-inflammatory agent that inhibits LPS-activated NO production (IC50: 0.449 μM). anti-inflammatory agent 23 exhibits good affinity for p65 protein.
T75013 SB26019
SB26019 is a potent anti-neuroinflammatory compound that modulates the activation of NF-κB by promoting the formation of monomeric α-tubulin. This action of SB26019, in turn, hinders the translocation of p65, signifying ...
T83661 17(R,S)-Benzo-Resolvin D1 17(R,S)-Benzo-RvD1,Benzo-RvD1
Benzo-resolvin D1 (benzo-RvD1), a derivative of the specialized pro-resolving mediator (SPM) RvD1, effectively reduces PDGF-BB-induced cytoskeletal alterations and PDGF-triggered migration in isolated human vascular smoo...
T71306 Gemfibrozil-d6
Gemfibrozil-d6 is intended for use as an internal standard for the quantification of gemfibrozil by GC- or LC-MS. Gemfibrozil is a peroxisome proliferator-activated reporter α and PPARγ agonist. In vivo, gemfibrozil redu...
T75010 TD1092
TD1092, a pan-IAP degrader, effectively degrades cIAP1, cIAP2, and XIAP, catalyzing the activation of Caspase 3/7 and fostering apoptosis in cancer cells through IAP degradation. It also obstructs the TNFα-mediated NF-κB...
T78730 TNF-α-IN-11
TNF-α-IN-11 (Compound 10) is a TNF-α inhibitor exhibiting a dissociation constant (K D) of 12.06 μM. By binding to TNF-α, it impedes TNF-α-induced caspase activation and the NF-κB signaling pathway. Additionally, it supp...
T72383 3,3-Dimethyl-1-butanol Neohexanol,DMB,DMB ; Neohexanol
3,3-Dimethyl-1-butanol (DMB) is an orally active compound that inhibits trimethylamine (TMA) and trimethylamine N-oxide (TMAO), along with the signaling pathways of p65 NF-κB and TGF-β1/Smad3. It holds potential for use ...
T36191 CAY10681
Inactivation of the tumor suppressor p53 commonly coincides with increased signaling through NF-κB in cancer. CAY10681 is a dual modulator of p53-MDM2 interaction and NF-κB signaling. It potently binds MDM2 (Ki = 250 nM)...
T74514 HD-TAC7
HD-TAC7, a potent PROTAC HDAC degrader, exhibits IC50 values of 3.6 μM, 4.2 μM, and 1.1 μM for HDAC1, HDAC2, and HDAC3, respectively. It effectively decreases NF-κB p65 in RAW 264.7 macrophages and is utilized in researc...
T83670 F1 TFA Tat-IKIP (46-60),Tat-Inhibitor of NF-κB Kinase-interacting Peptide
F1, an anti-inflammatory peptide, incorporates the HIV-1 Tat protein transduction domain linked with a 15-amino acid sequence from residues 46-60 of the inhibitor of NF-κB kinase-interacting peptide (IKIP). It effectivel...
T82189 HMGB1-IN-2
HMGB1-IN-2 (compound 15) is a selective inhibitor of the highly conserved nuclear protein HMGB1, demonstrating no inhibitory effect at an IC50 of 20.2 μM in RAW264.7 cells. At a concentration of 30 μM, HMGB1-IN-2 reduces...
T79671 NF-κB-IN-11 NF-κB
NF-κB-IN-11 (Compound 3i) is an inhibitor of NF-κB, effectively blocking TNF-α-induced NF-κB pathway activation and the nuclear translocation of NF-κB. It also reduces the expression levels of phospho-IKK, IκBα, and NF-κ...
T36486 Benpyrine
Benpyrine is a highly specific and orally active TNF-α inhibitor with a KD value of 82.1 μM. Benpyrine tightly binds to TNF-α and blocks its interaction with TNFR1, with an IC50 value of 0.109 μM. Benpyrine has the poten...
T38263 TBK1/IKKε-IN-4 TBK1/IKKε-IN-4
TBK1/IKKε-IN-4, a 6-aminopyrazolopyrimidine derivative, serves as a potent, selective inhibitor for TBK1 and IKKε, demonstrating IC50 values of 13 nM and 59 nM, respectively. This compound exhibits significantly reduced ...

Compounds

PTD-p65-P1 Peptide
TP1608
Synonym:
Target:
PTD-p65-P1 Peptide TFA
TP1395
Synonym:
Target:
NS-3-008 hydrochloride
T8494
Synonym: NS-3-008 HCl
Target: Others
Ossirene
T6761
Synonym: AS101
Target: IL Receptor, Caspase, Interleukin
Malachite green oxalate
TD0099
Synonym:
Target: Apoptosis, Others, IκB/IKK, NF-κB
CMV pp65(13-27)
T82701
Synonym:
Target:
GGTI 2147
T25450
Synonym: GGTI2147,Geranylgeranyl transferase inhibitor-2147,GGTI-2147
Target: NF-κB, Rho
IAXO-102
T11598
Synonym:
Target: TLR
SC75741
T6661
Synonym:
Target: Influenza Virus, NF-κB
ACHP
T22021
Synonym: IKK-2 Inhibitor VIII
Target: IκB/IKK
LTβR-IN-1
T11886
Synonym:
Target: Others, NF-κB, LTR
CORM-3
T6454
Synonym: CORM3
Target: Others, NF-κB, NOD-like Receptor (NLR)
JSH-23
T1930
Synonym:
Target: NF-κB
Anti-inflammatory agent 6
T63107
Synonym:
Target:
SRTCX1002
T26226
Synonym: SRTCX 1002,SRTCX-1002
Target:
K-14585
T27708
Synonym:
Target:
SRTCX1003
T28853
Synonym: SRTCX-1003,SRTCX 1003
Target:
SEMBL
T28749
Synonym:
Target:
Anti-inflammatory agent 65
T83047
Synonym:
Target: STING
EP12
T78846
Synonym:
Target: Apoptosis
Anti-inflammatory agent 60
T83052
Synonym:
Target: NF-κB
Anti-inflammatory agent 23
T64018
Synonym:
Target:
SB26019
T75013
Synonym:
Target:
17(R,S)-Benzo-Resolvin D1
T83661
Synonym: 17(R,S)-Benzo-RvD1,Benzo-RvD1
Target:
Gemfibrozil-d6
T71306
Synonym:
Target:
TD1092
T75010
Synonym:
Target:
TNF-α-IN-11
T78730
Synonym:
Target:
3,3-Dimethyl-1-butanol
T72383
Synonym: Neohexanol,DMB,DMB ; Neohexanol
Target:
CAY10681
T36191
Synonym:
Target:
HD-TAC7
T74514
Synonym:
Target:
F1 TFA
T83670
Synonym: Tat-IKIP (46-60),Tat-Inhibitor of NF-κB Kinase-interacting Peptide
Target:
HMGB1-IN-2
T82189
Synonym:
Target:
NF-κB-IN-11
T79671
Synonym:
Target: NF-κB
Benpyrine
T36486
Synonym:
Target:
TBK1/IKKε-IN-4
T38263
Synonym: TBK1/IKKε-IN-4
Target:
Cat No. Product Name Synonyms Targets
T4518 Licochalcone D ERK , NF-κB
Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotect...
T8160 EGCG Octaacetate Others , Antibacterial
EGCG Octaacetate, a prodrug of EGCG, is utilized to enhance the stability and bioavailability of EGCG in vivo. It has high efficacy, bioavailability, anti-oxidation, and anti-angiogenesis capacities.
TCS2170 2,5-Dihydroxyacetophenone Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP ERK , NF-κB , Tyrosinase
1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK...
T4237 Rubiadin-1-methyl ether Rubiadin 1-methyl ether Anti-infection , NF-κB
Rubiadin-1-methyl ether (Rubiadin 1-methyl ether) is a natural product.It inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nu...
TN1786 Isomerazin Isomeranzin ERK , NF-κB , AChE
Isomerazin (Isomeranzin) has anti-inflammatory activity, it suppresses inflammation by inhibiting M1 macrophage polarization through the p65, NF-κB and ERK pathway.
T2856 (-)-Epicatechin L-Epicatechin,Epicatechin,(-)-Epicatechol Ferroptosis , COX , Endogenous Metabolite
(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB.
T6S0117 Avicularin Fenicularin ERK
Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX...
T3772 Maslinic acid 2α-Hydroxyoleanoic Acid,2α-Hydroxyoleanolic acid,Crategolic acid NF-κB , HIV Protease , DNA/RNA Synthesis , Antibacterial
Maslinic acid (Crategolic acid) is a DNA polymerase B inhibitor.
T4S1469 Cucurbitacin IIb Apoptosis , Others
1. Cucurbitacin IIb is one of the major active compounds in Hemsleyadine tablets which have been used for clinical treatment of bacillary dysentery, enteritis and acute tonsilitis. 2. Cucurbitacin IIb exhibits its anti-i...
TN1674 Garcinone D Reactive Oxygen Species , Nrf2 , STAT
Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml; it exhibits dose-dependent enzyme-based microsomal aromatase inhibitory activity. Garcinone D inhibits p65 acti...
T3012 Mangiferin Alpizarin,Chinomin,Hedysarid Apoptosis , Others , NF-κB , Nrf2
Mangiferin (Hedysarid) is used for antidiabetes. Extracted from Mangifera indica L.
T6S1256 Ruscogenin NOS , NF-κB , NOD-like Receptor (NLR)
1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein ...
T6S1538 Neochlorogenic acid trans-5-O-Caffeoylquinic acid,Neochlorogenate,5-O-Caffeoylquinic acid TNF , NF-κB , COX , Antibacterial , Interleukin
Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.
T2913 Schisantherin A Schisanwilsonin H,Gomisin-C,Wuweizi ester-A,Schizantherin-A,Arisanschinin K NF-κB
Schisantherin A (Wuweizi ester-A) is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera, has been used as an antitussive, tonic, and sedative agent.
TN1341 8-Deoxygartanin Beta Amyloid , NF-κB , Parasite
8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it has multifunctional activities against Alzheimer's disease (AD) a...
T3753 Sinapinic Acid Sinapic acid,Synapoic acid Apoptosis , RAAS , Reactive Oxygen Species , HDAC
Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinap...
T7030 Anemarsaponin B p38 MAPK , NF-κB , MEK , COX , NO Synthase
Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B c...
T6S1572 Sauchinone ERK , p38 MAPK , NF-κB
1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative...
T6S1487 Ginsenoside Rg5 NF-κB , COX , IGF-1R
1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production and proinflammatory TNF-α secretion. 3. Ginsenoside Rg5 can ...
T15467 Helenalin Others
Helenalin is a selective inhibitor of transcription factor NF-κB by direct targeting of p65. It is an anti-inflammatory sesquiterpene lactone compound with alkylating activity. Through its ability to target the cysteine ...
TN5387 Grasshopper ketone ERK , p38 MAPK , NO Synthase , JNK
Grasshopper ketone, isolated from the brown alga Sargassum, is a potent inhibitor of LPS-induced NO production in RAW 264.7 cells and induces anti-inflammatory effects by inhibiting MAPK (ERK, JNK and p38) and NF-κB p65 ...
T27191 D-Mannuronic Acid
D-Mannuronic Acid is a blocker of the TLR2 and TLR4 downstream signaling pathway. D-Mannuronic Acid effectively inhibits mRNA expression of MyD88 and p65, major subunit of nuclear factor-kappaB.
TN1874 Liriodendrin ATPase , Potassium Channel , Prostaglandin Receptor
Liriodendrin regulates lung inflammation, the phosphorylation of the NF-kB (p65) and expression of vascular endothelial growth factor (VEGF). Liriodendrin has anti-inflammatory, antinociceptive, hypoglycemic activities a...
TN3922 Effusanin E PARP , NF-κB , Caspase , COX , Antifection
Effusanin E shows antibacterial and anti-cancer activities, it significantly inhibits cell proliferation and induces apoptosis in NPC cells by suppressing p50/p65 proteins to down-regulate COX-2 expression .
TN4490 Manassantin B ERK , BCL , p38 MAPK , TNF , NF-κB , JNK , STAT , Antifection
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-κB. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleu...
TN1009 Epimagnolin B NF-κB , NO Synthase , Prostaglandin Receptor
Epimagnolin B has anti-inflammatory activity, it can inhibit the production of NO and PGE(2) and the expression of respective enzyme iNOS and COX-2 through the suppression of I-kappaB-alpha degradation and nuclear transl...
TN4635 Neoechinulin A NADPH-oxidase , Beta Amyloid , ASK , IκB/IKK , p38 MAPK , TNF , NOS , NF-κB , COX , Prostaglandin Receptor
Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, it may block the phosphorylation of mitogen-activated protein kinase (MAPK) ...

Natural Products

Licochalcone D
T4518
Synonym:
Target: ERK, NF-κB
EGCG Octaacetate
T8160
Synonym:
Target: Others, Antibacterial
2,5-Dihydroxyacetophenone
TCS2170
Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP
Target: ERK, NF-κB, Tyrosinase
Rubiadin-1-methyl ether
T4237
Synonym: Rubiadin 1-methyl ether
Target: Anti-infection, NF-κB
Isomerazin
TN1786
Synonym: Isomeranzin
Target: ERK, NF-κB, AChE
(-)-Epicatechin
T2856
Synonym: L-Epicatechin,Epicatechin,(-)-Epicatechol
Target: Ferroptosis, COX, Endogenous Metabolite
Avicularin
T6S0117
Synonym: Fenicularin
Target: ERK
Maslinic acid
T3772
Synonym: 2α-Hydroxyoleanoic Acid,2α-Hydroxyoleanolic acid,Crategolic acid
Target: NF-κB, HIV Protease, DNA/RNA Synthesis, Antibacterial
Cucurbitacin IIb
T4S1469
Synonym:
Target: Apoptosis, Others
Garcinone D
TN1674
Synonym:
Target: Reactive Oxygen Species, Nrf2, STAT
Mangiferin
T3012
Synonym: Alpizarin,Chinomin,Hedysarid
Target: Apoptosis, Others, NF-κB, Nrf2
Ruscogenin
T6S1256
Synonym:
Target: NOS, NF-κB, NOD-like Receptor (NLR)
Neochlorogenic acid
T6S1538
Synonym: trans-5-O-Caffeoylquinic acid,Neochlorogenate,5-O-Caffeoylquinic acid
Target: TNF, NF-κB, COX, Antibacterial, Interleukin
Schisantherin A
T2913
Synonym: Schisanwilsonin H,Gomisin-C,Wuweizi ester-A,Schizantherin-A,Arisanschinin K
Target: NF-κB
8-Deoxygartanin
TN1341
Synonym:
Target: Beta Amyloid, NF-κB, Parasite
Sinapinic Acid
T3753
Synonym: Sinapic acid,Synapoic acid
Target: Apoptosis, RAAS, Reactive Oxygen Species, HDAC
anemarsaponin B
T7030
Synonym:
Target: p38 MAPK, NF-κB, MEK, COX, NO Synthase
Sauchinone
T6S1572
Synonym:
Target: ERK, p38 MAPK, NF-κB
Ginsenoside Rg5
T6S1487
Synonym:
Target: NF-κB, COX, IGF-1R
Helenalin
T15467
Synonym:
Target: Others
Grasshopper ketone
TN5387
Synonym:
Target: ERK, p38 MAPK, NO Synthase, JNK
D-Mannuronic Acid
T27191
Synonym:
Target:
Liriodendrin
TN1874
Synonym:
Target: ATPase, Potassium Channel, Prostaglandin Receptor
Effusanin E
TN3922
Synonym:
Target: PARP, NF-κB, Caspase, COX, Antifection
Manassantin B
TN4490
Synonym:
Target: ERK, BCL, p38 MAPK, TNF, NF-κB, JNK, STAT, Antifection
Epimagnolin B
TN1009
Synonym:
Target: NF-κB, NO Synthase, Prostaglandin Receptor
Neoechinulin A
TN4635
Synonym:
Target: NADPH-oxidase, Beta Amyloid, ASK, IκB/IKK, p38 MAPK, TNF, NOS, NF-κB, COX, Prostaglandin Receptor

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02387 NF-kB p65 Protein, Human, Recombinant (aa 1-306, GST) Human E. coli
RELA (v-rel reticuloendotheliosis viral oncogene homolog A), also known as Nuclear factor NF-kappa-B p65 subunit, or Transcription factor p65, is a transcription factor expressed in growth plate chondrocytes where it fac...
TMPJ-01426 SARS-CoV-2 NSP2 Protein (His) SARS-CoV-2 E. coli
The positive-stranded RNA genome of the coronaviruses is translated from ORF1 to yield polyproteins that are proteolytically processed into intermediate and mature nonstructural proteins (nsps). SARS-CoV 2 polyproteins i...
TMPH-02606 CR1L Protein, Mouse, Recombinant (His) Mouse E. coli
Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor,...
TMPY-04461 TRIB3 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
Tribbles homolog 3, also known as Neuronal cell death-inducible putative kinase, p65-interacting inhibitor of NF-kappa-B, SINK and TRIB3, is a Nucleus protein that belongs to the protein kinase superfamily and CAMK Ser/T...
TMPY-02893 NT5C3A/NT5C3 Protein, Human, Recombinant Human E. coli
NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded prot...
TMPJ-00338 LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
The type I transmembrane protein 15-leucine-rich repeat containing membrane protein (LRRC15) is a member of the LRR superfamily. The LRR family is a structural module for protein-protein and protein-matrix interactions u...
Cat No. Product Name
L3800 NF-κB Signaling Compound Library

729 compounds
A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening;
TargetMol