T12375 |
Fezagepras sodium
|
1254472-97-3
|
98%
|
|
Fezagepras sodium is an orally active GPR40 agonist and is an antagonist or inverse agonist for GPR84, with anti-fibrotic, anti-inflammatory and anti-proliferati...
|
T10889 |
CRTh2 antagonist 2
|
780763-95-3
|
98%
|
|
CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia.
|
T27328 |
FL104
|
885672-81-1
|
98%
|
|
FL104 is a potent agonist of small-molecule urotensin II receptor, pEC50= 7.11.
|
T67892 |
BTB09089
|
245728-44-3
|
98%
|
|
BTB09089 is a T cell death-associated gene 8 (TDAG8/GPR65)-specific agonist.BTB09089 induces TDAG8 expression and regulates cytokine production in T cells and ma...
|
T23434 |
GPR35 agonist 2
|
494191-73-0
|
98%
|
|
GPR35 agonist 2 is a potent GPR35 agonist.The EC50 values of GPR35 agonist 2 in the β-arrestin and Ca2+ release assays were 26 and 3.2 nM, respectively.
|
T11411 |
GLPG1205
|
1445847-37-9
|
98%
|
|
GLPG1205 is a potent, orally active GPR84 (G protein-coupled receptor) antagonist with anti-inflammatory activity. GLPG1205 shows good PK/PD characteristics and ...
|
T67791 |
BMS-903452
|
1339944-47-6
|
98%
|
|
BMS-903452 is a potent and selective GPR119 agonist with EC50 of 14 nM. BMS-903452 is indicated for the treatment of acute and chronic rodent diabetes. GPR119 wa...
|
TQ0241 |
TUG-770
|
1402601-82-4
|
98%
|
|
TUG-770 is a highly potent agonist of free fatty acid receptor 1 (FFA1/GPR40, EC50: 6 nM for hFFA1).
|
T10507 |
GPR40 Agonist 2
|
1147729-48-3
|
98%
|
|
GPR40 Agonist 2 is a GPR40 agonist extracted from patent WO2009054479A1. It can be used in the research of diabetes.
|
T11044 |
Dihydromunduletone
|
674786-20-0
|
98%
|
|
Dihydromunduletone (DHM) is a carotenoid derivative and selective strong adhesion G protein-coupled receptor (aGPCR) (GPR56 and GPR114/ADGRG5) antagonists, does ...
|
T4689 |
Palosuran hydrochloride 540769-28-6(free base)
|
T4689
|
98%
|
|
Palosuran is a new potent and specific antagonist of the human UT receptor with an IC50 of 3.6±0.2 nM.
|
T15283 |
Firuglipel
|
1371591-51-3
|
98%
|
|
Firuglipel is an orally available and selective agonist of GPR119.
|
T14200 |
AM-1638
|
1142214-62-7
|
98%
|
|
AM-1638 is a full agonist of GPR40/FFA1 (EC50: 0.16 μM).
|
T14202 |
AM-4668
|
1011531-27-3
|
98%
|
|
AM-4668 is a type 2 diabetes GPR40 agonist. For GPR40, in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), the EC50s are 3.6 nM and 36 nM, respec...
|
T15448 |
GW-1100
|
306974-70-9
|
98%
|
|
GW-1100 is a selective antagonist of GPR40 (pIC50: 6.9). GW1100 also plays the role of a GPR40 inverse agonist.
|
T2351L |
TAK-875 Hemihydrate
|
1374598-80-7
|
98%
|
|
TAK-875 is a selective GPR40 agonist with EC50 of 14 nM, 400-fold more potent than oleic acid.
|
T11452 |
GPR120 Agonist 1
|
1628448-77-0
|
98%
|
|
GPR120 Agonist 1 is a selective GPR120 agonist. In GPR120 transfected HEK293 cells, GPR120 Agonist 1 displays good EC50 of 42 nM and 77 nM for human and mouse GP...
|
T11460 |
GPR4 antagonist 1
|
1197879-16-5
|
98%
|
|
GPR4 antagonist 1 is a GPR4 antagonist (IC50: 189 nM).
|
TP2166 |
Urotensin II, mouse TFA (9047-55-6 free base)
|
TP2166
|
98%
|
|
Urotensin II, mouse TFA is an endogenous ligand for the orphan GPR14 or SENR. It is a potent vasoconstrictor.
|
T12778L |
RTI-13951-33
|
2244884-08-8
|
98%
|
|
RTI-13951-33 is an effective and brain-penetrant GPR88 agonist (EC50: 25 nM, in GPR88 cAMP functional assay).
|