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T1237 Azathioprine Azathioprine, an immunosuppressive agent, inhibits purine synthesis and GTP-binding protein Rac1 activation.
T1781 GW 9508 GW9508 is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.
T1793 MBX2982 MBX-2982 is a selective, orally-available GPR119 agonist, used for the treatment of diabetes.
T2036 GTPL5846 6-OAU(GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105...
T2058 Palosuran Palosuran (ACT-058362) is a new potent and specific antagonist of the human UT receptor.
T2088 APD 668 APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.
T2351 TAK875 TAK875 is a potent, selective and orally bioavailable GPR40 agonist.
T2351L TAK-875 Hemihydrate TAK-875 is a selective GPR40 agonist with EC50 of 14 nM, 400-fold more potent than oleic acid.
T2396 Ramatroban Ramatroban (BAY u3405) is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis. It has been used in trials studying the treatment of Asthma.
T2528 Latanoprost Latanoprost is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect.
T2664 Timapiprant OC000459 is a potent and selective D prostanoid receptor 2 (DP2) antagonist (IC50: 13 nM).
T2701 GSK1292263 GSK1292263 is a GPR119 agonist and has been investigated for the treatment of DIABETES MELLITUS, TYPE 2.
T3119 JNJ-63533054 JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM.
T3171 GSK137647A GSK137647A is a selective FFA4 agonist.
T3176 APD597 APD597 is a GPR119 agonist, used in the treatment of type 2 diabetes.
T3433 TUG-891 TUG-891 is a G protein-coupled receptor (GPCR) expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty a...
T3520 Setipiprant Setipiprant is an orally available, selective CRTH2 antagonist (IC50: 6.0 nM). CRTH2 is a G protein-coupled receptor for prostaglandin (PGD2). PGD2 is produced ...
T3965 Fevipiprant Fevipiprant is a selective, potent, reversible competitive CRTh2 antagonist.
T4312 GPR120 receptor agonist A potent and selective GPR120 receptor agonist.
T4626 TC-O 9311 TC-O 9311 is a potent GPR139 agonist.
T4689 Palosuran hydrochloride 540769-28-6(free base) Palosuran is a new potent and specific antagonist of the human UT receptor with an IC50 of 3.6±0.2 nM.
T6399 AZD1981 AZD1981 is an effective and specific CRTh2 (DP2) receptor antagonist (IC50: 4 nM), showing >1000-fold selectivity over more than 340 other enzymes and receptors...
T6855 HA15 HA15 targets specifically BiP/GRP78/HSPA5. HA15 exhibits anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells ...
T7010 VER155008 VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively, >100-fol...
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