T15448 |
GW-1100
|
306974-70-9
|
98%
|
|
GW-1100 is a selective antagonist of GPR40 (pIC50: 6.9). GW1100 also plays the role of a GPR40 inverse agonist.
|
T12778L |
RTI-13951-33
|
2244884-08-8
|
98%
|
|
RTI-13951-33 is an effective and brain-penetrant GPR88 agonist (EC50: 25 nM, in GPR88 cAMP functional assay).
|
T12883 |
Fezagepras
|
1002101-19-0
|
98%
|
|
Setogepram is an orally active GPR40 agonist and is an antagonist or inverse agonist of GPR84,with anti-inflammatory, anti-fibroticand anti-proliferative actions...
|
T11460 |
GPR4 antagonist 1
|
1197879-16-5
|
98%
|
|
GPR4 antagonist 1 is a GPR4 antagonist (IC50: 189 nM).
|
T62420 |
P2Y2R/GPR17 antagonist 1
|
2395016-49-4
|
98%
|
|
P2Y2R/GPR17 antagonist 1 (Compound 14m) is a dual P2Y2R and GPR17 antagonist. P2Y2R/GPR17 antagonist 1 shows IC50 values of 3.17 µM and 1.67 µM against P2Y2R and...
|
T15283 |
Firuglipel
|
1371591-51-3
|
98%
|
|
Firuglipel is an orally available and selective agonist of GPR119.
|
TQ0051 |
MK-7246
|
1218918-62-7
|
98%
|
|
MK-7246 is a potent and specific CRTH2 antagonist (Ki: 2.5 nM).
|
T7359 |
CAY10471 Racemate
|
844639-57-2
|
98%
|
|
CAY 10471 is a potent, highly selective CRTH2/DP 2 receptor antagonist. CAY10471 binds to the human CRTH2/DP2, DP1, and TP receptors( Ki values of 0.6, 1200, and...
|
T5406 |
SNAP 94847
|
487051-12-7
|
98%
|
|
SNAP-94847 is a selective and competitive MCH1 receptor (MCH1-R) antagonist (Ki: 2.2 nM). It has anxiolytic and antidepressant activity and reduces food intake i...
|
T10507 |
GPR40 Agonist 2
|
1147729-48-3
|
98%
|
|
GPR40 Agonist 2 is a GPR40 agonist extracted from patent WO2009054479A1. It can be used in the research of diabetes.
|
T14202 |
AM-4668
|
1011531-27-3
|
98%
|
|
AM-4668 is a type 2 diabetes GPR40 agonist. For GPR40, in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), the EC50s are 3.6 nM and 36 nM, respec...
|
TQ0241 |
TUG-770
|
1402601-82-4
|
98%
|
|
TUG-770 is a highly potent agonist of free fatty acid receptor 1 (FFA1/GPR40, EC50: 6 nM for hFFA1).
|
T12375 |
Fezagepras sodium
|
1254472-97-3
|
98%
|
|
Setogepram sodium salt is an orally active GPR40 agonist and is an antagonist or inverse agonist for GPR84, with anti-fibrotic, anti-inflammatory and anti-prolif...
|
T2351L |
TAK-875 Hemihydrate
|
1374598-80-7
|
98%
|
|
TAK-875 is a selective GPR40 agonist with EC50 of 14 nM, 400-fold more potent than oleic acid.
|
TP2166 |
Urotensin II, mouse TFA (9047-55-6 free base)
|
TP2166
|
98%
|
|
Urotensin II, mouse TFA is an endogenous ligand for the orphan GPR14 or SENR. It is a potent vasoconstrictor.
|
T11462 |
GPR84 antagonist 8
|
1445846-30-9
|
98%
|
|
GPR84 antagonist 8 is a selective GPR84 antagonist.
|
T11044 |
Dihydromunduletone
|
674786-20-0
|
98%
|
|
Dihydromunduletone (DHM) is a carotenoid derivative and selective strong adhesion G protein-coupled receptor (aGPCR) (GPR56 and GPR114/ADGRG5) antagonists, does ...
|
T11452 |
GPR120 Agonist 1
|
1628448-77-0
|
98%
|
|
GPR120 Agonist 1 is a selective GPR120 agonist. In GPR120 transfected HEK293 cells, GPR120 Agonist 1 displays good EC50 of 42 nM and 77 nM for human and mouse GP...
|
T14200 |
AM-1638
|
1142214-62-7
|
98%
|
|
AM-1638 is a full agonist of GPR40/FFA1 (EC50: 0.16 μM).
|
T15388 |
GLPG0974
|
1391076-61-1
|
98%
|
|
GLPG0974 is an antagonist of FFA2/GPR43 with IC50 of 9 nM.
|