ligand for e3 ligase

E3ligaseLigand 44 is a ligand for the E3 ligase and is employed in synthesizing [PROTACAR Degrader-7].

E3ligaseLigand 45 is an E3 ligase ligand used in the synthesis of Setidegrasib, a PROTAC degrader for Ras.

E3 ligase Ligand 65 is a ligand of E3 ligase, which is useful in the synthesis of AZ'3137.

E3 ligase Ligand 68, an E3 ligase ligand, is utilized in the synthesis of PROTACs, such as PROTACER Degrader-3.

E3 ligase Ligand 58 is an E3 ligase ligand (E3 ligase Ligand) employed in the synthesis of PROTACAH078.

E3 Ligase Ligand 21 (compound 2), a cereblon binder, facilitates the degradation of Ikaros or Aiolos via the ubiquitin proteasome pathway [1].

E3 Ligase Ligand 22 (compound 139) serves as a cereblon binder, facilitating the degradation of Ikaros or Aiolos via the ubiquitin proteasome pathway [1].

E3 Ligase Ligand 25, a component of Compd 1, serves as a ligand for E3 ligase. It is utilized in the synthesis of the PROTAC SOS1 degrader.

E3 ligase Ligand 23 is a cereblon binding agent that degrades Ikaros or Aiolos via the ubiquitin proteasome.

E3 ligase Ligand 8, a ligand for E3 ubiquitin ligase, can be connected to protein ligands through linkers to form PROTACs, which induce ubiquitination-mediated degradation of cancer-promoting proteins.

E3 ligase Ligand 10 serves as a ligand for E3 ubiquitin ligase and can be conjugated to a protein ligand through a linker, resulting in the formation of PROTACs. These PROTACs act as inducers of ubiquitination-mediated degradation, specifically targeting cancer-promoting proteins[1].

E3 ligase Ligand 13 is an E3 ubiquitin ligase ligand that can be employed to create PROTACs, which are connected to the ligand for the protein through a linker. PROTACs serve as inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

E3 ligase Ligand 9 is a compound that acts as a ligand for E3 ubiquitin ligase and can be attached to a protein ligand via a linker to form PROTACs or SNIPERs, which degrade cancer-promoting proteins through ubiquitination-mediated mechanisms[1].

E3 ligase Ligand 14 binds to E3 ubiquitin ligase and, when conjugated to a protein ligand via a linker, forms PROTACs that facilitate the ubiquitination-mediated degradation of cancer-promoting proteins[1].

Thalidomide-4-OH (E3 ligase Ligand 2) (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used to recruit of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) is a linker to form PROTACs

(S,R,S)-AHPC-Me-C10-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating a VHL ligand and a linker.

(S)-(S,R,S,R)-AHPC-Me-N3 is an E3 ligase ligand for PROTACSMARCA2 degrader-32, utilized in the synthesis of PROTACs.

(S)-Deoxy-thalidomide-Br is a ligand for E3 ligase, utilized in the synthesis of PROTACFHD-609.

Lenalidomide-F serves as the E3 ligase ligand for LWY713. LWY713 is a PROTAC-based FLT3 degrader (DC50= 0.64 nM) that selectively induces the degradation of FLT3 through a cereblon and proteasome-dependent mechanism.

4-Methylphenoxyacetic acid-Oxindole-CF3 is the E3 ligase ligand component of L134. It is suitable for use in PROTAC synthesis.

OICR-8268-acrylic acid is a ligand for E3 ubiquitin ligase. This compound can be linked to a target protein ligand via a linker to form OICR41114, which is applicable in cancer research.

N-Boc-SBP-0636457-OH is a ligand for the E3 ubiquitin ligase, facilitating the recruitment of the IAPE3 ligase for the degradation of Bcl-xL. It can be linked to a Bcl-xL ligand via a linker to form PROTACBcl-xLdegrader-1.

CRBN ligand-186 is a CRBN-type E3 ubiquitin ligase ligand, suitable for use in the preparation of PROTACs.

Nef ligand-2 is a compound that binds to Nef. It also serves as a ligand for E3 Ligase and represents the Nef Binder portion of FC-14369.