g12

G12 (Ras 5-17) is a wild-type Ras peptide comprising amino acids 5-17, specifically KLVVVGAGGVGKS, and serves as a control in studies investigating mutant Ras peptides such as V12.

KRas/son of sevenless 1 (SOS1) interaction inhibitor. Binds within nucleotide binding pocket of KRas (Kd values are 106 - 176 nM for wild type KRas and various KRas mutants). Inhibits nucleotide binding to KRas in a concentration dependent manner. Display

KRPEP-2D acetate was identified as a K-Ras(G12D) selective inhibitory peptide against the G12D mutant of K-Ras, which is a key member of the Ras protein family and an attractive cancer therapeutic target.

Relsipatide (BG128) is a dual agonist of the gastric inhibitory polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. It is utilized in antidiabetic research.

YFLLRNP is a biologically active peptide functioning as a partial agonist of PAR-1, selectively activating the G12/13 signaling pathway. At low concentrations, YFLLRNP (60 μM) does not activate Gq or Gi pathways.