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20

Compounds

Cat No. Product Name Synonyms Targets
T16695 Pyrintegrin Integrin
Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signal...
T27246 EG1 Others
EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.
T11996 MELK-8a hydrochloride MELK
MELK-8a hydrochloride is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK, IC50 = 2 nM). 
T38155 N-Acetyl-D-cysteine Reactive Oxygen Species
N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group.
T8987 Epiblastin A Casein Kinase
Epiblastin A is an inhibitor of Casein Kinase 1 (CK1). Epiblastin A engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs).
T2161 Cardiogenol C Wnt/beta-catenin
Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.
T24706 RBC10 RBC 10,RBC-10 GTPase
RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines.
T9681 MAK-683 hydrochloride Histone Methyltransferase
MAK683 hydrochloride is an inhibitor of embryonic ectoderm development (EED). MAK683 exhibits IC50s of 59, 26, 89 nM in EED Alphascreen binding, ELISA and LC-MS assay.
T21981 Phthalazinone pyrazole Aurora Kinase
Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity.
T6848 GSK1016790A GSK101 Calcium Channel , TRP/TRPV Channel
GSK1016790A (GSK101) (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34 nM in choroid plexus epithelial cells.
T1874 PPQ-102 PPQ102,CFTR Inhibitor,PPQ 102 CFTR , Autophagy
PPQ-102 (CFTR Inhibitor), an effective CFTR inhibitor, can completely inhibit CFTR chloride current (IC50: 90 nM).
T2431 ID-8 ID8 DYRK
ID-8, a DYRK inhibitor, sustains embryonic stem cell self-renewal in long-term culture.
T1759 OTSSP167 MELK inhibitor,OTS167 MELK
OTSSP167 (OTS167) is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity.
T21559 OTSSP167 hydrochloride MELK
OTSSP167 hydrochloride is a highly potent inhibitor of MELK(IC50 : 0.41 nM).
T11997 MELK-IN-1 Nintedanib Impurity L,MELK inhibitor 17 MELK
MELK-IN-1 (MELK inhibitor 17) is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK),(IC50:3nm;Ki:0.39 nM).
T8005 Cardiogenol C hydrochloride Cardiogenol C HCl,Cardiogenol C Wnt/beta-catenin
Cardiogenol C hydrochloride (Cardiogenol C) can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).
T11571 HLY78 4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine Wnt/beta-catenin
HLY78 (4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine) targets the DIX domain of Axin, is an activator of the Wnt/β-catenin signaling pathway and can enhance Axin-LRP6 binding to promote Wnt signaling.
T3221 Oct3/4-inducer-1 2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile Others , OCT
Oct3/4-inducer-1 (2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile) is an OCT3/4 inducer that promotes the expression and stabilization of OCT3/4 and enhances its transcriptional activity in a variety of human cells.
T7196 HG-10-102-01 LRRK2
HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).
TP1286 Carcinoembryonic Antigen CEA Others
Carcinoembryonic antigen (CEA) is a protein that is present in certain tissues of a developing baby (fetus)
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TargetMol