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Dolutegravir intermediate-1 (1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid) is a new synthetic Dolutegravir intermediate. Dolutegravir is an integrase inhibitor developed for the treatment of human immunodeficiency virus (HIV)-1 infection.

Sitagliptin Intermediate 2 is a useful organic compound that has been used in life science related research.

cholesterol-absorption inhibitor Intermediate 2 is a potent and orally active cholesterol absorption inhibitor that reduces blood cholesterol levels.

Ketoconazole Intermediate 1e ((cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4- methylbenzenesulfonate) is a ketoconazole intermediate.

Type III-Intermediate 8 is a useful organic compound for research related to life sciences and the catalog number is T9562.

Type III-Intermediate7 is a useful organic compound for research related to life sciences and the catalog number is T9563.

CRAC intermediate 1 is a key intermediate used in the synthesis of the CRAC ion channel series of compounds, details from patent WO 2010122089.

CRAC intermediate 2 is used as an intermediate compound in the synthesis of CRAC inhibitors.

LX-4211 intermediate is a synthetic intermediate of LX-4211, a potent SGLT1 2 inhibitor used as an antidiabetic agent.

PDE4 inhibitor intermediate 1 is a PDE4 inhibitor synthesis intermediate.

P62-mediated mitophagy inducer (PMI) is a regulator of mitophagy.

Doxapram intermediate-1 (Compound II) is a pyrrolidone derivative that significantly stimulates the central nervous system (CXS) and respiratory system in dogs, usually accompanied by varying degrees of blood pressure activity.

Transcriptional Intermediary Factor 2 (TIF2) (740-753) is a 14-amino acid peptide coactivator, encompassing residues 740-753 of the TIF-2 protein.

Exatecan Intermediate 1 is a useful organic compound for research related to life sciences. The catalog number is T67020 and the CAS number is 110351-94-5.

Dacomitinib Intermediate 2 (N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine) has anticancer activity and can be used to study lung cancer.

SC209 Intermediate-1 (Compound A7a), an ADC linker, facilitates the synthesis of antibody-drug conjugates (ADCs) [1].

LX-2761 intermediate is a synthetic intermediate of LX-2761, a chemically stable and potent SGLT1 2 inhibitor.

AcLys-PABC-VC-Aur0101 intermediate-1, a cathepsin-cleavable ADC linker, facilitates the production of antibody-drug conjugates [1].

SC209 intermediate-2 (Compound A9), functioning as an ADC Linker [1], serves as an intermediate for the ADC cytotoxin SC209.

(rac)-Exatecan Intermediate 1 is a camptothecin derivative, a potential topoisomerase I inhibitor, used in tumor research.

Exatecan Intermediate 2 (compound B) is a precursor used in the synthesis of Exatecan (DX-8951), an anticancer agent classified among the camptothecin analogs. Exatecan operates by interacting with DNA to disrupt the proliferation and division of tumor cells, effectively inhibiting tumor growth. It is primarily employed in research targeting various cancers, including ovarian, lung, and breast cancer.

Exatecan Intermediate 6 serves as an intermediate in the synthesis of Exatecan (DX-8951), a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg mL), utilized in cancer research. Additionally, Exatecan Intermediate 6 is employed in the preparation of Antibody-Drug Conjugates (ADCs).

(R)-Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1. Known as compound 6, Exatecan Intermediate 1 serves as a precursor in the synthesis of Exatecan, a camptothecin-class anticancer agent. Exatecan acts by interfering with DNA to inhibit the proliferation and division of tumor cells, effectively suppressing tumor growth. It is primarily researched for its potential use in treating various cancers, including ovarian, lung, and breast cancer.

Taltobulinintermediate-4 is an intermediate used in the synthesis of Taltobulin, a common toxin component (ADC Cytotoxin) in ADC preparation and a potent inhibitor of microtubule tubulin (Microtubule Tubulin). Taltobulin disrupts the polymerization of microtubules, induces mitotic arrest, and triggers apoptosis (apoptosis).