folate

Folic acid is an orally active essential nutrient involved in the synthesis of DNA/RNA and the production and maintenance of new cells. It exhibits antidepressant-like effects and can reduce the risk of neural tube defects in newborns. Folate deficiency can cause megaloblastic anemia, macrocytic anemia, neural tube closure defects, tumors, and aging-related diseases. Folic acid is also commonly used in research on folate deficiency-related conditions and to induce acute kidney injury models.

Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Transporter 2 Inhibitor.

Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.

DSPE-PEG46-Folate is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Folate-PEG3-NHS ester is a PROTAC linker from the PEG family and is utilized in the synthesis of PROTAC molecules.

Folate-PEG1-mal is a PROTAC linker of the PEG class, used in the synthesis of PROTAC molecules.

Hexaglutamate folate is a naturally occurring form of folic acid. The bioavailability of dietary folate may be limited by the need for the glutamate moieties to be deconjugated before absorption. Folate deficiency in humans results in anemia, neural tube

Folate sodium, as a member of the vitamin B family, can stimulate the hematopoietic system. Folic acid can be used in the treatment and prevention of folate deficiencies and megaloblastic anemia.

Triglutamate folate is a bioactive chemical.

Folate-PEG2-amine is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Folate-PEG3-alkyne is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Folate-PEG3-amine is a three-unit polyethylene glycol (PEG) linker, which is cleavable. This linker is specifically employed in the synthesis of antibody-drug conjugates (ADCs).

DSPE-PEG-Folate (Mw 3350), a derivative of PEG with folic acid content, exhibits targeting capability by binding to folate receptors on cancer cells. It forms micelles/lipid bilayers, facilitating its use in targeted drug delivery system research [1] [2] [3].

Cholesterol-PEG-Folate (MW 2000), an excipient, facilitates the preparation of folate-conjugated PEG-liposomes [1].

DSPE-PEG-Folate (MW 5000), a derivative of polyethylene glycol (PEG) integrated with folic acid, demonstrates a specific targeting ability by binding to folate receptors on cancer cells. This compound forms micelles/lipid bilayers, facilitating its application in targeted drug delivery system research [1] [2].

Folate-MS432 is a PROTAC that degrades MEKs selectively in cancer cells via folate receptor-dependent pathways.

DSPE-PEG-Folate, MW 2000 is a folic acid-conjugated PEG (polyethylene glycol) derivative known for its targeting capabilities by binding to folate receptors in cancer cells. It forms micelles/lipid bilayers and is utilized in the study of targeted drug delivery systems.

Cholesterol-PEG-Folate (MW 1000) is a cholesterol PEG derivative capable of self-assembling into micelles, providing an extended half-life in vivo. It is applicable for research in drug delivery.

Cholesterol-PEG-Folate (MW 3400) is a cholesterol PEG derivative capable of forming micelles through molecular self-assembly and possessing an extended half-life in vivo. It is applicable for research in drug delivery.

Cholesterol-PEG-Folate (MW 5000) is a cholesterol PEG derivative capable of forming micelles through molecular self-assembly, offering an extended half-life in vivo. It is applicable in drug delivery research.

DSPE-PEG-Folate (MW 1000) is a folate-containing PEG derivative that specifically binds to folate receptors in cancer cells. It forms micelles/lipid bilayers and is utilized in the study of targeted drug delivery systems.

DSPE-PEG-Folate (MW 3400) is a PEG derivative that includes folate, enabling targeted binding to folate receptors in cancer cells. It forms micelles/lipid bilayers, making it applicable for research in targeted drug delivery systems.

N-TETAMINE-pSar45-Folate is a lipid formed by the combination of Folic acid units and N-tetramine-pSar45. It is utilized in the preparation of lipid nanoparticles for drug delivery.

16:0 FolatecapPE is a lipid layer incorporating a phospholipid surfactant. It is applicable for the preparation of lipid nanoparticles used in drug delivery.