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Cat No. | Product Name | Synonyms | Targets |
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T38629 | Folate-PEG3-alkyne | Folate-PEG3-alkyne | |
Folate-PEG3-alkyne is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syste... | |||
T40818 | Folate-PEG3-amine | Folate-PEG3-amine | |
Folate-PEG3-amine is a three-unit polyethylene glycol (PEG) linker, which is cleavable. This linker is specifically employed in the synthesis of antibody-drug conjugates (ADCs). | |||
T38492 | Folate-PEG2-amine | Folate-PEG2-amine | |
Folate-PEG2-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system... | |||
T34942 | Triglutamate folate | Pteglu3 | |
Triglutamate folate is a bioactive chemical. | |||
T25496 | Hexaglutamate folate | Pteglu6 | |
Hexaglutamate folate is a naturally occurring form of folic acid. The bioavailability of dietary folate may be limited by the need for the glutamate moieties to be deconjugated before absorption. Folate deficiency in hum... | |||
T17861 | DSPE-PEG46-Folate | Others | |
DSPE-PEG46-Folate is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system... | |||
T17984 | Folate-PEG3-azide | Others | |
Folate-PEG3-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system... | |||
T82378 | Folate-MS432 | PROTACs | |
Folate-MS432 is a PROTAC that degrades MEKs selectively in cancer cells via folate receptor-dependent pathways. | |||
T74308 | DSPE-PEG-Folate | ||
DSPE-PEG-Folate (Mw 3350), a derivative of PEG with folic acid content, exhibits targeting capability by binding to folate receptors on cancer cells. It forms micelles/lipid bilayers, facilitating its use in targeted dru... | |||
T77274 | DSPE-PEG-Folate (MW 5000) | ||
DSPE-PEG-Folate (MW 5000), a derivative of polyethylene glycol (PEG) integrated with folic acid, demonstrates a specific targeting ability by binding to folate receptors on cancer cells. This compound forms micelles/lipi... | |||
T77270 | Cholesterol-PEG-Folate (MW 2000) | ||
Cholesterol-PEG-Folate (MW 2000), an excipient, facilitates the preparation of folate-conjugated PEG-liposomes [1]. | |||
T25358 | EC-17 free acid | EC17,EC 17,EC-17,FTIC-Folate,Folate-FTIC | |
EC17 is a FITC conjugated folic acid, also known as Folate-FITC. It also acts as an FRα-targeting agent that fluoresces at 500nm. EC17 is a conjugate consisting of fluorescein isothiocyanate (FITC) conjugated with folate... | |||
T31508 | Diopterin | Folate monoglutamate,Pteroyl diglutamic acid | |
Diopterin is a folic acid analog. | |||
T3279 | Silver sulfadiazine | Silvadene,Dermazin,Flamazine | DNA/RNA Synthesis , Antibacterial , Antibiotic |
Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity. | |||
T7593 | Levomefolate calcium | Antifolate | |
Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements. | |||
T7598 | Calcium N5-methyltetrahydrofolate | NSC173328 | Others , Antifolate |
Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers | |||
T26636 | Antifolate C2 | AGF 154,AGF154,AGF-154 | Others |
Antifolate C2 (AGF 154) has antitumor activity with an IC of 0.14 nM measured in a growth inhibition assay of human tumor cells.Antifolate C2 can be used for the study of cancer and autoimmune diseases. | |||
T26635 | Antifolate C1 | AGF 94,AGF94,AGF-94 | |
Antifolate C1 is an inhibitor of de novo purine biosynthesis. Antifolate C1 has selectivity for cellular uptake by high affinity folate receptors and the proton-coupled folate transporter (PCFT) over the reduced folate c... | |||
T68232 | Epofolate | ||
Epofolate is folate receptor-targeting antimitotic agent with potential antineoplastic activity. Folate receptor-targeted epothilone BMS753493 contains an epothilone moiety linked to a single folate molecule. Mediated th... | |||
T29460 | 5-Methyldihydrofolate | ||
5-Methyldihydrofolate is the primary biologically active form of folate used for DNA reproduction, the cysteine cycle, and the regulation of homocysteine. | |||
T7593L | Levomefolate sodium | L 5 MTHF sodium,L-5-MTHF sodium,L5MTHF sodium, | |
Levomefolate calcium is a primary biologically active form of folate used at the cellular level for dna reproduction, the cysteine cycle and the regulation of homocysteine | |||
T32705 | Levomefolate magnesium | L-Methylfolate magnesium | |
Levomefolate magnesium is the magnesium salt of the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human ... | |||
T29461 | 5-Methyltetrahydrofolate triglutamate | 5-Me-Thf(glu)3 | |
5-Methyltetrahydrofolate triglutamate is a form of folic acid. | |||
T20340 | 10-Formyldihydrofolate | ||
10-Formyldihydrofolate is a Methotrexate metabolite. It inhibits thymidylate synthetase and glycinamide ribotide transformylase. | |||
T32706 | Levomefolate calcium pentahydrate | ||
Levomefolate calcium pentahydrate is the calcium salt of 5-methyltetrahydrofolic acid, a biologically active form of folic acid that functions, in conjunction with Vitamin B12. Levomefolate is included in formulations of... | |||
T2627 | Nolatrexed dihydrochloride | Thymitaq,AG 337 | DNA/RNA Synthesis |
Nolatrexed dihydrochloride (Thymitaq) is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidyla... | |||
T0959 | Ethopabate | Ethyl pabate | Others , Antibiotic , Parasite |
Ethopabate (Ethyl pabate) is an inhibitor of folate metabolism, used as a coccidiostat in poultry. | |||
T76766 | Mirvetuximab | M9346A | Antifolate |
Mirvetuximab (M9346A) is a novel folate receptor α (FRα) monoclonal antibody targeting anti-FOLR1 (folate receptor 1). Mirvetuximab soravtansine is often conjugated with platinum compounds or other compounds to form anti... | |||
T6120 | Pralatrexate | Folotyn,10-Propargyl-10-deazaaminopterin | Apoptosis , DHFR , Antifolate , TAM Receptor |
Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive act... | |||
T15827 | LY 345899 | DHFR | |
LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for MTHFD1). | |||
T1485 | Methotrexate | NCI-C04671,WR19039,Amethopterin,CL14377 | Apoptosis , Dehydrogenase , DNA/RNA Synthesis , Antifolate |
Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR. Methotrexate has antimetabolic, antitumor, and immunosuppressive activities, and is commonly used in rheumatoid arthritis and v... | |||
T76720 | Farletuzumab | MORAb-003 | Antifolate |
Farletuzumab (MORAb-003) is a potent inhibitor of folate receptor-α (FRα). Farletuzumab is a humanized monoclonal antibody with a high affinity for FRα. Farletuzumab inhibits the growth of cells that overexpress FRα. Far... | |||
T0020 | Sodium 4-aminosalicylate dihydrate | Sodium 4-Aminosalicylate,4-Amino-salicylic acid sodium salt | Free radical scavengers , NF-κB , Antibacterial , Antibiotic |
Sodium 4-aminosalicylate dihydrate (4-Amino-salicylic acid sodium salt) is the sodium salt form of aminosalicylic acid, an analog of para-aminobenzoic acid (PABA) with antitubercular activity. Sodium 4-aminosalicylate di... | |||
T0189L | Pemetrexed disodium | LY-231514,LY231514 disodium,Pemetrexed | Apoptosis , DHFR , DNA/RNA Synthesis , Antifolate , Autophagy |
Pemetrexed disodium (LY-231514) is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesothelioma. Pemetrexed disodium therapy has b... | |||
T2160 | Suramin Sodium Salt | BAY-205,Suramin hexasodium salt,NF-060 | Apoptosis , Phosphatase , SARS-CoV , Sirtuin , Reverse Transcriptase , Topoisomerase , Parasite |
Suramin Sodium Salt (BAY-205) is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth f... | |||
T34184 | Pteroyltyrosine | ||
Pteroyltyrosine is an analog of tyrosyl folate used in folate radioassay. | |||
T29284 | 10-Formylpteroylpentaglutamate | ||
10-Formylpteroylpentaglutamate is a folate conjugate. | |||
T25981 | Pralatrexate, (S)- | ||
Pralatrexate, (S)- is a folate analog dihydrofolate reductase (DHFR) inhibitor exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities. Pralatrexate selectively ... | |||
T25980 | Pralatrexate, (R)- | ||
Pralatrexate, (R)- is a folate analog dihydrofolate reductase (DHFR) inhibitor exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities. Pralatrexate selectively ... | |||
T26007 | Pyrrofolic acid | ||
Pyrrofolic acid shows high anti-folate biological activity for S. faecalis. | |||
T70583 | Pemetrexed Diethyl Ester | ||
Pemetrexed Diethyl Ester is a protected intermediate in the synthesis of Pemetrexed, a multi-targeted anti-folate that inhibits thymidylate synthase as well as other folate dependent enzymes. | |||
T24966 | 11-Oxahomoaminopterin | NSC-325304,NSC 325304,NSC325304 | |
11-Oxahomoaminopterin exhibits antifolate activity against two folate-requiring microorganisms and inhibited Lactobacillus casei DHFR. | |||
T24572 | OSI-7904L free acid | OSI 7904,OSI-7904L,OSI7904,OSI 7904L,OSI7904L,OSI-7904 | |
OSI-7904L is a folate-based thymidylate synthase inhibitor. It also has antimalarial and antitumor properties. | |||
T24991 | 8-Deazahomofolic acid | ||
8-Deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor. | |||
T25374 | Emofolin sodium | NSC139490,MeTHHF disodium,NSC-139490,NSC 139490 | |
Emofolin sodium is the sodium salt of a synthetic antimetabolite analogue of folate with antineoplastic activity,which competes for the folate binding site of the enzyme dihydrofolate reductase, resulting in inhibition o... | |||
T24963 | 10-Methyl-10-deazaaminopterin | ||
10-Methyl-10-deazaaminopterin is a folate analog that shows antitumor activity. | |||
T12635L | Plevitrexed | BGC9331,ZD 9331 | Others |
Plevitrexed is taken up via the α-folate receptor as well as the reduced folate carrier. Plevitrexed is an orally active and effective thymidylate synthase (TS) inhibitor (Ki: 0.44 nM). Plevitrexed is used for gastric ca... | |||
T39757 | EC2629 | EC2629 | |
EC2629 is a highly potent folate- receptor-targeted DNA crosslinking agent. | |||
T25332 | Dihydrohomofolic acid | ||
Dihydrohomofolic acid is a substrate for dihydrofolate reductase that produces tetrahydro-homo folate which in turn suppresses thymidylate synthetase and then DNA synthesis. | |||
T29434 | 4-Desacetylvinblastine hydrazide | DAVLBH,Deacetylvinblastine hydrazide,Desacetylvinblastine hydrazide | |
Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T21367 | Tetrahydrofolic acid | 5,6,7,8-tetrahydrofolic acid,folate-H4,Tetrahydropteroylglutamic acid,th-folate | Endogenous Metabolite |
Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) is a vitamin B9 derivative that is a common one-carbon donor in organisms and is involved in growth and metabolism. | |||
T31836 | Folate sodium | Folic acid, monosodium salt,Folvite sodium | |
Folate sodium, as a member of the vitamin B family, can stimulate the hematopoietic system. Folic acid can be used in the treatment and prevention of folate deficiencies and megaloblastic anemia. | |||
T0062 | Folic acid | Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,Folacin | DNA/RNA Synthesis , Endogenous Metabolite |
Folic acid (Vitamin B9)(Vitamin M; Vitamin B9) is indispensable for the production and maintenance of new cells, for DNA/RNA synthesis. | |||
T1153 | Trimethoprim | NIH 204,BW 56-72,NSC-106568 | DHFR , DNA/RNA Synthesis , Antifolate , Antibacterial , Antibiotic |
Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Tra... | |||
T13516 | 5-Methyltetrahydrofolic acid | 5-Methyl THF | Endogenous Metabolite |
5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid and a methylated derivate of tetrahydrofolate. It is the predominant natural dietary folate and the principal form of folate in plas... | |||
T1721 | 2'-Deoxyuridine | Uracil deoxyriboside,2-deoxyuridine,2'-dU | Others , DNA/RNA Synthesis , Endogenous Metabolite |
2'-Deoxyuridine (2-deoxyuridine). An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12... | |||
T7094 | Levomefolic Acid | 5-MTHF | Reactive Oxygen Species , Endogenous Metabolite |
Levomefolic Acid (5-MTHF) is a natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions. Levomefolinic acid is used a... | |||
T4909 | N-Acetyl-DL-methionine | Others , Endogenous Metabolite | |
N-acetyl-L-methionine is nutritionally and metabolically equivalent to L-methionine. Methionine is a dietary indispensable amino acid required for normal growth and development of humans, other mammals, and avian species... | |||
T4877 | L-Homocystine | Endogenous Metabolite | |
Homocystine is the double-bonded form of homocysteine, but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Increasing evidence supports a role for an ele... | |||
T32704 | Levoleucovorin | levo-Folinic,LFP-754,Levofolinic acid,Levofolene,LFP 754 | |
Levoleucovorin, as a folate analog, consists of the pharmacologically active isomer of leucovorin. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01815 | FOLR1 Protein, Human, Recombinant (His) | Human | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i... | |||
TMPY-06022 | FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i... | |||
TMPJ-00147 | FOLR1 Protein, Human, Recombinant (hFc) | Human | Human Cells |
Folate receptor alpha(FOLR) belongs to the folate receptor family, and is primarily expressed in tissues of epithelial origin. It is also expressed in kidney, lung and cerebellum. The secreted form is derived from the me... | |||
TMPY-01803 | FOLR1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i... | |||
TMPY-01280 | FOLR2 Protein, Human, Recombinant (His) | Human | HEK293 |
Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant ... | |||
TMPY-06928 | FOLR1 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i... | |||
TMPY-00381 | PSMA Protein, Human, Recombinant (His) | Human | HEK293 |
Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote... | |||
TMPY-02417 | FOLR1 Protein, Canine, Recombinant (hFc) | Canine | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i... | |||
TMPY-00622 | FOLR1 Protein, Canine, Recombinant (His) | Canine | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i... | |||
TMPY-06929 | FOLR1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i... | |||
TMPJ-00148 | FOLR1 Protein, Rhesus macaque, Recombinant (His) | Rhesus Macaque | Human Cells |
Folate receptor alpha(FOLR) belongs to the folate receptor family, and is primarily expressed in tissues of epithelial origin. It is also expressed in kidney, lung and cerebellum. The secreted form is derived from the me... | |||
TMPY-04128 | FOLR1 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i... | |||
TMPY-00543 | FOLR1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i... | |||
TMPK-00878 | FOLR3 Protein, Human, Recombinant (His) | Human | HEK293 |
Folic acid and folate receptors (FOLRs) play an important role in the downregulation of homocysteine (Hcy), a risk factor of Alzheimer's disease, thrombosis, neuropsychiatric illness and fractures. | |||
TMPK-00150 | FOLR1 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required ... | |||
TMPY-01390 | PSMA Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote... | |||
TMPH-03190 | CPG2 Protein, Pseudomonas sp., Recombinant (GST) | Pseudomonas sp. | E. coli |
Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity. | |||
TMPK-01171 | FOLR4/Juno Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Izumo1 is the only essential sperm-egg fusion protein currently known on mammalian sperm, and its egg receptor (Juno; formerly Folr4) was recently discovered. Male knockout mice for Izumo1 and female knockout mice for Ju... | |||
TMPK-00585 | FOLR4/Juno Protein, Human, Recombinant (His) | Human | HEK293 |
Izumo1 is the only essential sperm-egg fusion protein currently known on mammalian sperm, and its egg receptor (Juno; formerly Folr4) was recently discovered. Male knockout mice for Izumo1 and female knockout mice for Ju... | |||
TMPY-06960 | PSMA Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote... | |||
TMPK-00521 | PSMA Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate... | |||
TMPK-00371 | PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated | Mouse | HEK293 |
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate... | |||
TMPY-05269 | PSMA Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote... | |||
TMPK-00370 | PSMA Protein, Human, Recombinant (hFc) | Human | HEK293 |
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate... | |||
TMPK-00522 | PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated | Cynomolgus | HEK293 |
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate... | |||
TMPH-03581 | Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His) | Staphylococcus epidermidis | E. coli |
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
TMPH-00608 | Dihydrofolate reductase Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
TMPH-03535 | Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc) | Staphylococcus aureus | E. coli |
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
TMPH-01224 | Dihydrofolate reductase Protein, Human, Recombinant (His) | Human | E. coli |
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds... | |||
TMPJ-00989 | MTHFS Protein, Human, Recombinant (His) | Human | E. coli |
5-formyltetrahydrofolate cyclo-ligase (MTHFS) belongs to the 5-formyltetrahydrofolate cyclo-ligase family. It is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, contr... | |||
TMPH-03585 | Dihydropteroate synthase Protein, S. haemolyticus, Recombinant (His) | Staphylococcus haemolyticus | E. coli |
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | |||
TMPY-05055 | GGH/Glutamyl hydrolase gamma Protein, Human, Recombinant (His) | Human | HEK293 |
gamma-Glutamyl hydrolase (GGH) regulates intracellular folates and antifolates such as methotrexate (MTX) for proper nucleotide biosynthesis and antifolate-induced cytotoxicity, respectively. GGH is a ubiquitously-expres... | |||
TMPJ-00932 | PBLD Protein, Human, Recombinant (His) | Human | E. coli |
Phenazine Biosynthesis-Like Domain-Containing protein (PBLD) belongs to the phenazine biosynthesis-like protein (PhzF) family, which is expressed in most tissues. PBLD takes part in the MAPK signaling pathway, and is inv... | |||
TMPJ-01299 | RTBDN Protein, Human, Recombinant (His) | Human | Human Cells |
Human Retbindin is a 229 amino acid secreted protein that belongs to the folate receptor family. The gene that encodes retbindin exists as two alternatively spliced isoforms. Retbindin is first expressed in retina. It ma... | |||
TMPJ-01118 | GNMT Protein, Human, Recombinant (His) | Human | E. coli |
Glycine N-Methyltransferase (GNMT) is a tetrameric cytosolic protein. GNMT catalyzes the synthesis of N-methylglycine from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. It can affects DNA methylation b... | |||
TMPH-01616 | LRP2 Protein, Human, Recombinant (mFc) | Human | HEK293 |
Multiligand endocytic receptor. Acts together with CUBN to mediate endocytosis of high-density lipoproteins. Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B. In the... | |||
TMPY-04159 | Ebola virus EBOV (Subtype Sudan, strain Gulu) Glycoprotein/GP Protein (aa 1-637, His) | EBOV | Baculovirus-Insect Cells |
The fourth gene of the EBOV genome encodes a 16-kDa envelope-attached glycoprotein (GP) and a 11 kDa secreted glycoprotein (sGP). Both GP and sGP have an identical 295-residue N-terminus, however, they have different C-t... | |||
TMPY-00236 | Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) GP-RBD/Glycoprotein Protein (His) | EBOV | HEK293 |
The fourth gene of the EBOV genome encodes a 16-kDa envelope-attached glycoprotein (GP) and a 11 kDa secreted glycoprotein (sGP). Both GP and sGP have an identical 295-residue N-terminus, however, they have different C-t... | |||
TMPY-00243 | Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) GP-RBD/Glycoprotein Protein (hFc) | EBOV | HEK293 |
The fourth gene of the EBOV genome encodes a 16-kDa envelope-attached glycoprotein (GP) and a 11 kDa secreted glycoprotein (sGP). Both GP and sGP have an identical 295-residue N-terminus, however, they have different C-t... | |||
TMPY-00307 | Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) EBOV-G/Glycoprotein Protein (His) | EBOV | HEK293 |
The fourth gene of the EBOV genome encodes a 16-kDa envelope-attached glycoprotein (GP) and a 11 kDa secreted glycoprotein (sGP). Both GP and sGP have an identical 295-residue N-terminus, however, they have different C-t... | |||
TMPY-00234 | Ebola virus EBOV (subtype Sudan, strain Gulu) GP-RBD/Glycoprotein Protein (hFc) | EBOV | HEK293 |
The fourth gene of the EBOV genome encodes a 16-kDa envelope-attached glycoprotein (GP) and a 11 kDa secreted glycoprotein (sGP). Both GP and sGP have an identical 295-residue N-terminus, however, they have different C-t... | |||
TMPY-00038 | Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP Protein (His) | EBOV | Baculovirus-Insect Cells |
The fourth gene of the EBOV genome encodes a 16-kDa envelope-attached glycoprotein (GP) and a 11 kDa secreted glycoprotein (sGP). Both GP and sGP have an identical 295-residue N-terminus, however, they have different C-t... | |||
TMPY-00043 | Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP Protein (His) | EBOV | Baculovirus-Insect Cells |
The fourth gene of the EBOV genome encodes a 16-kDa envelope-attached glycoprotein (GP) and a 11 kDa secreted glycoprotein (sGP). Both GP and sGP have an identical 295-residue N-terminus, however, they have different C-t... | |||
TMPY-00199 | Ebola virus EBOV (Subtype Sudan, strain Gulu) Glycoprotein/GP1 (mucin domain deleted) Protein (aa 1-320, His) | EBOV | Baculovirus-Insect Cells |
The fourth gene of the EBOV genome encodes a 16-kDa envelope-attached glycoprotein (GP) and a 11 kDa secreted glycoprotein (sGP). Both GP and sGP have an identical 295-residue N-terminus, however, they have different C-t... | |||
TMPY-00255 | Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) GP2/Glycoprotein Protein (Fc) | EBOV | HEK293 |
The fourth gene of the EBOV genome encodes a 16-kDa envelope-attached glycoprotein (GP) and a 11 kDa secreted glycoprotein (sGP). Both GP and sGP have an identical 295-residue N-terminus, however, they have different C-t... | |||
TMPY-00178 | Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP-RBD (Receptor Binding Domain) Protein (hFc) | EBOV | HEK293 |
The fourth gene of the EBOV genome encodes a 16-kDa envelope-attached glycoprotein (GP) and a 11 kDa secreted glycoprotein (sGP). Both GP and sGP have an identical 295-residue N-terminus, however, they have different C-t... | |||
TMPY-00245 | Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Makona-Kissidougou-C15) GP/Glycoprotein Protein (His) | EBOV | HEK293 |
The fourth gene of the EBOV genome encodes a 16-kDa envelope-attached glycoprotein (GP) and a 11 kDa secreted glycoprotein (sGP). Both GP and sGP have an identical 295-residue N-terminus, however, they have different C-t... | |||
TMPY-00041 | Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP1 Protein (His) | EBOV | Baculovirus-Insect Cells |
The fourth gene of the EBOV genome encodes a 16-kDa envelope-attached glycoprotein (GP) and a 11 kDa secreted glycoprotein (sGP). Both GP and sGP have an identical 295-residue N-terminus, however, they have different C-t... | |||
TMPY-00102 | Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP-RBD Protein (His) | EBOV | HEK293 |
The fourth gene of the EBOV genome encodes a 16-kDa envelope-attached glycoprotein (GP) and a 11 kDa secreted glycoprotein (sGP). Both GP and sGP have an identical 295-residue N-terminus, however, they have different C-t... | |||
TMPY-00235 | Ebola virus EBOV (subtype Sudan, strain Gulu) GP/Glycoprotein Protein (His) | EBOV | HEK293 |
The fourth gene of the EBOV genome encodes a 16-kDa envelope-attached glycoprotein (GP) and a 11 kDa secreted glycoprotein (sGP). Both GP and sGP have an identical 295-residue N-terminus, however, they have different C-t... | |||
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