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Microbiology/Virology HSV

HSV

Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known by their taxonomical names Human alphaherpesvirus 1 and Human alphaherpesvirus 2, are two members of the human Herpesviridae family, a set of new viruses that produce viral infections in the majority of humans. Both HSV-1 (which produces most cold sores) and HSV-2 (which produces most genital herpes) are common and contagious. They can be spread when an infected person begins shedding the virus.
Cat No. product name
T8972 FIT-039 FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1). FIT-039 inhibits replication of HSV-1 (IC50 of 0.6...
T7983 Isoborneol Isoborneol is a monoterpene alcohol, with neuroprotective and antiviral activities
T15394 Glyceryl monocaprate Glyceryl monocaprate is a capric acid against 1-monoglyceride gram-positive bacterial infections. It has an inhibitory effect on Herpes Simplex Virus (HSV). It a...
TN2231 Soyasaponin II Soyasaponin II has antiviral effects, it can inhibit the replication of human cytomegalovirus, influenza virus, and human immunodeficiency virus type 1.
TN1846 Kushenol W Kushenol W is a natural product
TN1843 Kushenol K Kushenol K is a potent and Selective Inhibitor of cGMP Phosphodiesterase 5, it also has inhibitory effects on diacylglycerol acyltransferase (DGAT). Kushenol K s...
TN1671 Ganoderone A Ganoderone A exhibits potent inhibitory activity against herpes simplex virus.
T7972 Gallic aldehyde Gallic aldehyde shows potent antiviral activity against HSV-1.
T5542 Tiglic acid Tiglic acid is a thick, syrupy poisonous liquid, C5H8O2, derived from croton oil, having a spicy odor and used in making perfumes and flavoring agents
T13041 Surfactin Surfactin is a potent cyclic lipopeptide biosurfactants that mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes, with an...
T4S0999 Isoxanthohumol 1. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV). 2. Isoxanthohumol is a polyphenol wi...
T0718 Brivudine Brivudine, an antiviral medicine, is used in the therapy of herpes zoster.
T2616 PIK93 PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.
T2843 Aloe-emodin Aloe-emodin is an interferon-inducing agent, for JEV (IC50=1 μg/mL) and EV71(IC50=0.33 μg/mL ).
T1643 Penciclovir Penciclovir is a Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor. In HSV infected cells, penciclovir is phosphorylated by viral thymidine kinase and subse...
T2504 Pritelivir Pritelivir (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).
T6742 2-Deoxy-D-glucose 2-Deoxy-D-glucose is an analog of glucose, which is a glycolytic inhibitor with antiviral activity.
T12908 SIBA SIBA is a synthetic analogue of SAH, acts as an inhibitor of S-adenosylmethionine-mediated transmethylation. SIBA can interfere with a variety of enzymatic act...
T10445 B220 B220, an antiviral agent, inhibits the growth of HSV-1, HSV-2, and human cytomegalovirus (CMV).
TN5014 Shoreic acid Shoreic acid exhibits antibacterial activity against E. coli, P. aeruginosa, S. aureus, and B. subtilis with activity indices (AI) of 0.2, 0.3, 0.5 and 0.4, resp...
TN3010 4,5-Di-O-caffeoylquinic acid methyl ester 4,5-Di-O-caffeoylquinic acid methyl ester shows high efficiency and low toxicity with antivirus activity against RSV.
TN4587 Mulberrofuran C Mulberrofuran C shows protective effects on t-BHP-induced oxidative stress with the EC50 value of 0.41 ± 0.48 uM ; it also shows protective effects on glutamate...
TN4585 Moronic acid Moronic acid shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. It also shows significant anti-HIV activity (EC(50) 186)...
TN4456 Lucidadiol Lucidadiol exhibits butyrylcholinesterase-inhibitory activity at concentrations up to 200 uM, it also possesses inhibitory activity against acetylcholinesterase ...
TN4455 Lucialdehyde B Lucialdehyde B exhibits potent inhibitory activity against herpes simplex virus. It shows cytotoxic effects on Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, an...
TN3925 Eichlerianic acid Eichlerianic acid is a trypanocidal compound with an IC50 value of 10 mg/mL. Eichlerianic acid may have antiviral activity against Herpes simplex virus types I a...
TN3559 Cabraleahydroxylactone Cabraleahydroxylactone displays antimycobacterial activity against Mycobacterium tuberculosis, it is weakly cytotoxic to a breast cancer (BC) cell line.It shows ...
TN2894 3,5-Di-O-caffeoylquinic acid methyl ester 3,5-Di-O-caffeoylquinic acid methyl ester exhibits potent inhibitory activities against the formation of advanced glycation end products (AGEs); it exhibits cyto...
T10615 BRL44385 BRL44385 is an effective and selective inhibitor of the replication of HSV-1 and HSV2, Epstein-Barr virus (EBV), and varicella-zoster virus (VZV).
TN2872 3,4-Di-O-caffeoylquinic acid methyl ester 3,4-Di-O-caffeoylquinic acid methyl ester shows high efficiency and low toxicity with antivirus activity against RSV; it exhibits cytotoxicity actions against hu...
TN2821 24-Methylenecycloartanol acetate 24-Methylenecycloartanol acetate has antiviral and antimicrobial activities.
T3S2325 Ardisiacrispin A Ardisiacrispin A has cytotoxic activity toward HepG2 cancer cell with the GI(50) value of 1.56μM, it could inhibit the proliferation of Bel-7402 cells by induci...
T3930 Taraxeryl acetate Taraxeryl acetate shows the significant antiviral activity against herpes simplex virus (type II). It has less effect on cell cycle arrest and apoptosis of AGS c...
T2S1975 Ponicidin Ponicidin has anti-leukemia, immunoregulatory and anti-inflammatory functions, it also has anti-viral function especially in the upper respiratory tract infectio...
T13209 Tromantadine Tromantadine is an amantadine derivative with antiherpetic activity (inhibits HSV-1 and HSV-2 replication).
T13209L Tromantadine hydrochloride Tromantadine hydrochloride is an amantadine derivative with antiherpetic activity (inhibits HSV-1 and HSV-2 replication).
T1646 Famciclovir Famciclovir is a Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor. The mechanism of action of famciclovir is as a DNA Polymerase Inhibitor, and DN...
FIT-039
T8972CAS 1113044-49-7
FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1). FIT-039 inhibits replication of HSV-1 (IC50 of 0.6...
Isoborneol
T7983CAS 124-76-5
Isoborneol is a monoterpene alcohol, with neuroprotective and antiviral activities
Glyceryl monocaprate
T15394CAS 26402-22-2
Glyceryl monocaprate is a capric acid against 1-monoglyceride gram-positive bacterial infections. It has an inhibitory effect on Herpes Simplex Virus (HSV). It a...
Soyasaponin II
TN2231CAS 55319-36-3
Soyasaponin II has antiviral effects, it can inhibit the replication of human cytomegalovirus, influenza virus, and human immunodeficiency virus type 1.
Kushenol W
TN1846CAS 254886-76-5
Kushenol W is a natural product
Kushenol K
TN1843CAS 101236-49-1
Kushenol K is a potent and Selective Inhibitor of cGMP Phosphodiesterase 5, it also has inhibitory effects on diacylglycerol acyltransferase (DGAT). Kushenol K s...
Ganoderone A
TN1671CAS 873061-79-1
Ganoderone A exhibits potent inhibitory activity against herpes simplex virus.
Gallic aldehyde
T7972CAS 13677-79-7
Gallic aldehyde shows potent antiviral activity against HSV-1.
Tiglic acid
T5542CAS 80-59-1
Tiglic acid is a thick, syrupy poisonous liquid, C5H8O2, derived from croton oil, having a spicy odor and used in making perfumes and flavoring agents
Surfactin
T13041CAS 24730-31-2
Surfactin is a potent cyclic lipopeptide biosurfactants that mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes, with an...
Isoxanthohumol
T4S0999CAS 70872-29-6
1. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV). 2. Isoxanthohumol is a polyphenol wi...
Brivudine
T0718CAS 69304-47-8
Brivudine, an antiviral medicine, is used in the therapy of herpes zoster.
PIK93
T2616CAS 593960-11-3
PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.
Aloe-emodin
T2843CAS 481-72-1
Aloe-emodin is an interferon-inducing agent, for JEV (IC50=1 μg/mL) and EV71(IC50=0.33 μg/mL ).
Penciclovir
T1643CAS 39809-25-1
Penciclovir is a Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor. In HSV infected cells, penciclovir is phosphorylated by viral thymidine kinase and subse...
Pritelivir
T2504CAS 348086-71-5
Pritelivir (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).
2-Deoxy-D-glucose
T6742CAS 154-17-6
2-Deoxy-D-glucose is an analog of glucose, which is a glycolytic inhibitor with antiviral activity.
SIBA
T12908CAS 35899-54-8
SIBA is a synthetic analogue of SAH, acts as an inhibitor of S-adenosylmethionine-mediated transmethylation. SIBA can interfere with a variety of enzymatic act...
B220
T10445CAS 112228-65-6
B220, an antiviral agent, inhibits the growth of HSV-1, HSV-2, and human cytomegalovirus (CMV).
Shoreic acid
TN5014CAS 21671-00-1
Shoreic acid exhibits antibacterial activity against E. coli, P. aeruginosa, S. aureus, and B. subtilis with activity indices (AI) of 0.2, 0.3, 0.5 and 0.4, resp...
4,5-Di-O-caffeoylquinic acid methyl ester
TN3010CAS 188742-80-5
4,5-Di-O-caffeoylquinic acid methyl ester shows high efficiency and low toxicity with antivirus activity against RSV.
Mulberrofuran C
TN4587CAS 77996-04-4
Mulberrofuran C shows protective effects on t-BHP-induced oxidative stress with the EC50 value of 0.41 ± 0.48 uM ; it also shows protective effects on glutamate...
Moronic acid
TN4585CAS 6713-27-5
Moronic acid shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. It also shows significant anti-HIV activity (EC(50) 186)...
Lucidadiol
TN4456CAS 252351-95-4
Lucidadiol exhibits butyrylcholinesterase-inhibitory activity at concentrations up to 200 uM, it also possesses inhibitory activity against acetylcholinesterase ...
Lucialdehyde B
TN4455CAS 480439-84-7
Lucialdehyde B exhibits potent inhibitory activity against herpes simplex virus. It shows cytotoxic effects on Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, an...
Eichlerianic acid
TN3925CAS 56421-13-7
Eichlerianic acid is a trypanocidal compound with an IC50 value of 10 mg/mL. Eichlerianic acid may have antiviral activity against Herpes simplex virus types I a...
Cabraleahydroxylactone
TN3559CAS 35833-69-3
Cabraleahydroxylactone displays antimycobacterial activity against Mycobacterium tuberculosis, it is weakly cytotoxic to a breast cancer (BC) cell line.It shows ...
3,5-Di-O-caffeoylquinic acid methyl ester
TN2894CAS 159934-13-1
3,5-Di-O-caffeoylquinic acid methyl ester exhibits potent inhibitory activities against the formation of advanced glycation end products (AGEs); it exhibits cyto...
BRL44385
T10615CAS 114778-60-8
BRL44385 is an effective and selective inhibitor of the replication of HSV-1 and HSV2, Epstein-Barr virus (EBV), and varicella-zoster virus (VZV).
3,4-Di-O-caffeoylquinic acid methyl ester
TN2872CAS 114637-83-1
3,4-Di-O-caffeoylquinic acid methyl ester shows high efficiency and low toxicity with antivirus activity against RSV; it exhibits cytotoxicity actions against hu...
24-Methylenecycloartanol acetate
TN2821CAS 1259-94-5
24-Methylenecycloartanol acetate has antiviral and antimicrobial activities.
Ardisiacrispin A
T3S2325CAS 23643-61-0
Ardisiacrispin A has cytotoxic activity toward HepG2 cancer cell with the GI(50) value of 1.56μM, it could inhibit the proliferation of Bel-7402 cells by induci...
Taraxeryl acetate
T3930CAS 2189-80-2
Taraxeryl acetate shows the significant antiviral activity against herpes simplex virus (type II). It has less effect on cell cycle arrest and apoptosis of AGS c...
Ponicidin
T2S1975CAS 52617-37-5
Ponicidin has anti-leukemia, immunoregulatory and anti-inflammatory functions, it also has anti-viral function especially in the upper respiratory tract infectio...
Tromantadine
T13209CAS 53783-83-8
Tromantadine is an amantadine derivative with antiherpetic activity (inhibits HSV-1 and HSV-2 replication).
Tromantadine hydrochloride
T13209LCAS 41544-24-5
Tromantadine hydrochloride is an amantadine derivative with antiherpetic activity (inhibits HSV-1 and HSV-2 replication).
Famciclovir
T1646CAS 104227-87-4
Famciclovir is a Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor. The mechanism of action of famciclovir is as a DNA Polymerase Inhibitor, and DN...