β-lysine

(R) - β - lysine is a functional modifier of elongation factor P (EF-P).

L-Lysine (Aminutrin) is one of nine essential amino acids in humans required for growth and tissue repair, Lysine is supplied by many foods, especially red meats, fish, and dairy products. Lysine seems to be active against herpes simplex viruses and present in many forms of diet supplements. The mechanism underlying this effect is based on the viral need for amino acid arginine; lysine competes with arginine for absorption and entry into cells. Lysine inhibits HSV growth by knocking out arginine.

(±)-Carnitine chloride (Monocamin) is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine.

UNC0638 is an inhibitor of β-protein lysine methyltransferases G9a(IC50<15 nM) and GLP(IC50=19 nM) with excellent potency and selectivity over a wide range of epigenetic and non-epigenetic targets.

Elongation factor P-IN-1, a potent elongation factor P (EFP) inhibitor and β-lysine derivative compound, affects E. coli proliferation rate[1].

Elongation factor P-IN-2, a β-lysine derivative, is a potent inhibitor of elongation factor P (EFP) that affects E. coli proliferation rates [1].

DL-β-Hydroxybutyryl coenzyme A lithium, an intermediate in butyric acid fermentation and lysine and tryptophan metabolism, is synthesized from β-hydroxybutyric acid by short-chain-CoA synthase [1] [2].