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Cat No. | Product Name | Synonyms | Targets |
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T12715 | Reverse transcriptase-IN-1 | HIV Protease | |
Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7 nM. | |||
T72203 | Reverse transcriptase-IN-3 | ||
Reverse transcriptase-IN-3, a pyrimidine-5-carboxamide derivative, functions as an inhibitor of HIV-1, demonstrating potent activity against both wild-type and mutant strains of HIV-1. | |||
T72206 | Reverse transcriptase-IN-4 | ||
Reverse transcriptase-IN-4 is a potent, selective non-nucleoside reverse transcriptase (NNRT) inhibitor, demonstrating an EC50 of 0.053 μM against wild-type HIV-1 and 0.26 μM for the E138K HIV-1 mutant. | |||
T7447 | Adefovir | HBV , Reverse Transcriptase , Telomerase | |
Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infection. | |||
T12609 | R-10015 | LIM Kinase , Reverse Transcriptase | |
R-10015 is a highly potent and selective LIMK inhibitor that blocks LIMK by binding to the ATP-binding pocket. It inhibits human LIMK1 with an IC50 value of 38 nM. It also exerts broad-spectrum antiviral effects and may ... | |||
T9223 | RO-0335 | Reverse Transcriptase | |
RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical is... | |||
T16530 | BF738735 | Antiviral , PI4K | |
BF738735 is a selective inhibitor of phosphatidylinositol 4-kinase III beta (PI4KIIIβ, IC50 = 5.7 nM) showing higher activity over α(IC50 = 1.7 μM). BF738735 exhibits a broad spectrum of antiviral activity. | |||
T10133 | 3'-Azido-3'-deoxy-5-methylcytidine | Antiviral , HIV Protease | |
3'-Azido-3'-deoxy-5-methylcytidine inhibits HIV-1 reverse transcriptase(EC50 = 0.06 μM) and is an effective inhibitor of xenotropic murine leukemia-related retrovirus (XMRV, CC50 = 43.5 μM). | |||
T16098 | Islatravir | MK-8591 | HIV Protease , Reverse Transcriptase |
Islatravir (MK-8591) is an effective anti-HIV-1 agent. It acts as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively). | |||
T2330 | Rilpivirine | TMC278,R278474,DB08864 | HIV Protease , Reverse Transcriptase |
Rilpivirine (R278474) is a diarylpyrimidine derivative and reverse transcriptase inhibitor with antiviral activity against HIV-1 that is used in the treatment of HIV infections. | |||
T3632 | Doravirine | MK-1439 | HIV Protease , Reverse Transcriptase |
Doravirine (MK-1439) is a non-nucleoside reverse transcriptase inhibitor, used in the treatment of HIV/AIDS. | |||
T5981 | 2,2'-Anhydrouridine | O2,2'-Cyclouridine,2,2'-Cyclouridine | Antiviral , Reverse Transcriptase |
2,2'-Anhydrouridine (2,2'-Cyclouridine) is a research tool for antiviral and anticancer studies. | |||
T1267 | Abacavir | Epzicom,Ziagen,Abacavir sulfate | Apoptosis , HIV Protease , Reverse Transcriptase |
Abacavir (Ziagen) is a nucleoside reverse transcriptase inhibitor analog of guanosine. This agent decreases HIV viral loads, retards or prevents the damage to the immune system, and reduces the risk of developing AIDS. | |||
T6214 | Emtricitabine | FTC,Emtriva,BW1592 | HIV Protease , Reverse Transcriptase |
Emtricitabine (FTC) (FTC), a nucleoside reverse transcriptase inhibitor, exhibits inhibition activity against human immunodeficiency virus (HIV) and hepatitis B virus. | |||
T2578 | Didanosine | ddI,2',3'-Dideoxyinosine | HIV Protease , Reverse Transcriptase |
Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM). | |||
T27154 | Dexelvucitabine | D-D-4FC,DPC-817,RVT,beta-D-D-4FC,DFC | Reverse Transcriptase |
Dexelvucitabine (RVT), a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection. | |||
T1815 | Dapivirine | R147681,TMC120 | Apoptosis , HIV Protease , Reverse Transcriptase , Autophagy |
Dapivirine (R147681) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. | |||
T2551 | Etravirine | TMC125,R165335 | HIV Protease , Reverse Transcriptase |
Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that confer resistance to the two most commonly prescribe... | |||
T2409 | Tenofovir alafenamide | GS-7340 | HIV Protease , Reverse Transcriptase |
Tenofovir alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir. | |||
T7111 | Tenofovir Disoproxil | GS 4331,Bis(POC)-PMPA | HBV , HIV Protease , Reverse Transcriptase |
Tenofovir Disoproxil (GS 4331) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. | |||
T1649 | Tenofovir | PMPA,TDF,GS 1278 | HBV , HIV Protease , Reverse Transcriptase |
Tenofovir (GS 1278) is an adenine analog REVERSE TRANSC-RIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIV... | |||
T19963 | Alizarin Complexone | Alizarin Fluorine Blue,Alizarin-3-methyliminodiacetic acid | Reverse Transcriptase |
Alizarin Complexone (Alizarin-3-methyliminodiacetic acid) is an inhibitor of Rous-associated virus 2 reverse transcriptase. Alizarin Complexone can be used as a calcium-tracer and a chelating agent for biological studies... | |||
T0682 | Lamivudine | GR109714X,BCH-189 | HIV Protease , Reverse Transcriptase |
Lamivudine (BCH-189) is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease. | |||
T1675 | Adefovir dipivoxil | Hepsera,GS 0840,Preveon | Others , HBV , Reverse Transcriptase |
Adefovir dipivoxil (GS 0840) is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity against hepatitis B virus (HBV), herpes virus, and human immunodeficienc... | |||
T6367 | Abacavir sulfate | Abacavir Hemisulfate,1592U89,ABC sulfate,Ziagen | Apoptosis , HIV Protease , Reverse Transcriptase |
Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity | |||
T0110 | Zalcitabine | Dideoxycytidine,ddC,NSC 606170,Ro 24-2027/000,2',3'-Dideoxycytidine | HIV Protease , Reverse Transcriptase |
Zalcitabine (Dideoxycytidine)(Dideoxycytidine;ddC; 2', 3'-Dideoxycytidine) is a nucleoside analog reverse transcriptase inhibitor (NRTI); At low concentrations, It can potently inhibit HIV replication by binding to rever... | |||
T1595 | Nevirapine | NSC 641530,BI-RG 587,NVP | HIV Protease , Reverse Transcriptase |
Nevirapine (NVP) is a benzodiazepine non-nucleoside reverse transcriptase inhibitor. In combination with other antiretroviral drugs, nevirapine reduces HIV viral loads and increases CD4 counts, thereby retarding or preve... | |||
T7282 | Tenofovir alafenamide hemifumarate | GS-7340 (hemifumarate),Tenofovir alafenamide fumarate | HIV Protease , Reverse Transcriptase |
Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir (TFV) | |||
T1404 | Stavudine | d4T,Sanilvudine,BMY-27857,NSC 163661 | Apoptosis , Nucleoside Antimetabolite/Analog , HIV Protease , NOD-like Receptor (NLR) , Reverse Transcriptase , Autophagy |
Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV. | |||
T4326 | AG 555 | Tyrphostin B46,Tyrphostin AG 555 | EGFR , Reverse Transcriptase |
AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor. | |||
T2393 | Efavirenz | EFV,DMP 266,Sustiva,Stocrin,L-743726 | HIV Protease , Reverse Transcriptase , Autophagy |
Efavirenz (DMP 266) is a Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of efavirenz is as a Non-Nucleoside Reverse Transcriptase Inhibitor, and Cytochrome P... | |||
T2409L | Tenofovir Disoproxil Fumarate | GS-1278 Disoproxil Fumarate,Tenofovir DF | HBV , HIV Protease , Reverse Transcriptase |
Tenofovir Disoproxil Fumarate (GS-1278 Disoproxil Fumarate) is a pro-drug, fumaric acid salt form of tenofovir, a nucleoside reverse transcriptase inhibitor analog of adenosine. Tenofovir disoproxil fumarate is prescribe... | |||
T14489 | Azvudine | FNC,RO-0622 | HCV Protease , HBV , HIV Protease , Reverse Transcriptase |
Azvudine (FNC) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine inhibits NRTI-resistant viral strains. Azvudine exerts highly potent inhibition on HIV-1... | |||
T7212 | Delavirdine mesylate | U 90152 (mesylate),BHAP-U 90152 (mesylate),Delavirdine (mesylate) | HIV Protease , Reverse Transcriptase |
Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI). | |||
T7700 | Lersivirine | Lersivirine(UK 453061),UK-453061 | HIV Protease , Reverse Transcriptase |
Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy. | |||
T9854 | HIV-1 inhibitor-6 | 3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo- | HIV Protease |
HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing inhibitor that blocks HIV replication. | |||
T2160 | Suramin Sodium Salt | BAY-205,Suramin hexasodium salt,NF-060 | Apoptosis , Phosphatase , SARS-CoV , Sirtuin , Reverse Transcriptase , Topoisomerase , Parasite |
Suramin Sodium Salt (BAY-205) is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth f... | |||
T3172 | Trovirdine | LY300046 | HIV Protease |
Trovirdine (LY300046) is a thiourea non-nucleoside reverse transcriptase inhibitor. | |||
T7455 | 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride | HIV Protease | |
4-Chloro-2-(trifluoroacetyl)aniline hydrochloride is an inhibitor of HIV-1 RT (HIV reverse transcriptase) . | |||
T21474 | Navuridine | AZddU,CS 87,CS-87,AzUrd,3'-Azido-2',3'-dideoxyuridine,AZdU | HIV Protease |
Navuridine (AZdU) is an oral active inhibitor of HIV reverse transcriptase with a relatively short half-life. | |||
T1513 | Telbivudine | NV 02B,L-Thymidine,Epavudine | Others , HBV , Reverse Transcriptase |
Telbivudine (NV 02B) is a Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of telbivudine is as a Nucleoside Reverse Transcriptase Inhibitor. The chemical classification of tel... | |||
T12814 | (S)-Tenofovir | (S)-PMPA,(S)-GS 1278,(S)-TDF | Others |
(S)-Tenofovir ((S)-PMPA) is the less active S-enantiomer of Tenofovir which is a nucleotide reverse transcriptase inhibitor. | |||
T68103 | MK-6186 | Reverse Transcriptase | |
MK-6186 is a novel non-nucleoside reverse transcriptase inhibitor with antiviral activity for the study of viral infections. | |||
T15210 | Elsulfavirine | Elpida,VM-1500 | HIV Protease |
Elsulfavirine (VM-1500) is an HIV-1 infection reverse transcriptase inhibitor. It is a new anti-HIV drug. | |||
T28255 | Opaviraline | GW420867X,GW-867,HBY-1293,GW867,GW-420867X | HIV Protease |
Opaviraline (GW-420867X) is a potent reverse transcriptase inhibitor that inhibits Human immunodeficiency virus 1 and has the potential to treat HIV infection. | |||
T31860 | Fosdevirine | GSK-2248761A,IDX 899,GSK 2248761A,GSK 2248761,GSK-2248761,IDX-12899,GSK2248761,FDV,GSK2248761A | HIV Protease |
Fosdevirine (GSK2248761) is a selective and potent non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity for the study of neurological related disorders such as late-onset epilepsy. | |||
T15436 | GSK2838232 | HIV Protease | |
GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates,GSK2838232 is novel human immune virus (HIV) maturation inhibitor. | |||
T68103L | Mk-6186 HCl | Mk-6186 HCl(1034474-19-5 Free base) | HIV Protease , Reverse Transcriptase |
MK-6186 HCl, a novel non-nucleoside reverse transcriptase inhibitor with antiviral activity, can be used to study HIV. | |||
T27260 | Emivirine | MKC442,MKC-442,MKC 442,DRG-0302,DRG 0302,DRG0302 | HIV Protease |
Emivirine (MKC-442) is a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1. | |||
T2279 | Tizoxanide | Desacetyl-nitazoxanide,TIZ | Antiviral , HIV Protease , Antibacterial , Autophagy |
Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine. Lamivudine (2', 3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI). |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3795 | Corilagin | Apoptosis , TLR , Reverse Transcriptase , Antibacterial , Autophagy | |
Corilagin has anti-inflammatory activity. Corilagin has a significant antitumour potential and lower toxicity in normal cells in vitro.Corilagin can enhance the cytotoxicity of both cisplatin and doxorubicin on the Hep3B... | |||
T6519 | Gramine | NSC 16892,Donaxine | Adiponectin receptor , Reverse Transcriptase , Adrenergic Receptor |
Gramine (Donaxine), a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for AdipoR2 and AdipoR1, respectively. Gramine is als... | |||
T2901 | Daidzin | NPI-031D,Daidzein 7-O-glucoside,Daidzoside,Daidzein 7-glucoside | Dehydrogenase , Reverse Transcriptase , Mitochondrial Metabolism |
Daidzin (Daidzoside) is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities. | |||
T3578 | Pyridoxal phosphate | PLP,PAL-P,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate | Reverse Transcriptase , Endogenous Metabolite |
Pyridoxal phosphate (Vitamin B6 phosphate) is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and d... | |||
T6S0923 | Hypericin | Hypericine,Cyclosan | Apoptosis , Antiviral , Influenza Virus , Tyrosine Kinases , Antibacterial , PKC |
1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL... | |||
TN1427 | Baicalin methyl ester | Anti-infection | |
Baicalin methyl ester shows inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT). | |||
T3730 | Methyl gallate | NSC 363001,Gallicin,Gallic acid methyl ester,Gallincin | Reactive Oxygen Species , HIV Protease , Reverse Transcriptase , Antibacterial |
Methyl gallate (Gallincin) is a reverse transcriptase inhibitor with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibition activities. | |||
T4S1718 | Punicalin | HBV , HIV Protease | |
Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-dependent manner, with an IC50 of 0.11 microg/ml (0.14 microM). | |||
T9086 | Deoxythymidine-5'-triphosphate trisodium | dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),Deoxythymidine-5'-triphosphate (dTTP) trisodium salt | DNA/RNA Synthesis |
Deoxythymidine-5'-triphosphate trisodium (Deoxythymidine-5'-triphosphate (dTTP) trisodium salt) is one of the four natural deoxynucleotides. It is used for the biosynthesis of deoxyribonucleic acid by DNA polymerase and ... | |||
TN4934 | Salaspermic acid | HIV Protease | |
Salaspermic acid is an inhibitor of HIV reverse transcriptase and HIV replication in H9 lymphocyte cells. | |||
T2S0605 | Liquidambaric lactone | HIV Protease | |
Liquidambaric lactone is a compound isolated from Euonymus grandiflorus Wall.Liquidambaric lactone may have inhibitory HIV-1 reverse transcriptase activity. | |||
T13796 | Nigranoic acid | HIV Protease | |
Nigranoic acid is a natural product,and inhibits HIV-1 reverse transcriptase. | |||
TN5243 | Vitexilactone | NADPH-oxidase , HIV Protease , Antifection | |
Vitexilactone is a HIV-1 reverse transcriptase inhibitor in virtual screening against Indonesian Herbal Database using AutoDock4 performed on HIV-1 reverse transcriptase. It has trypanocidal activity, the minimum lethal ... | |||
T74196 | Inophyllum B | ||
Inophyllum B ((+)-Inophyllum B), a compound extracted from the acetone extract of the giant African snail, Achatina fulica [1], serves as a potent inhibitor of HIV Reverse Transcriptase, displaying an IC50 value of 38 nM... | |||
TN5133 | 3',5,5',7-Tetrahydroxy-4',6-dimethoxyflavone | HIV Protease , Topoisomerase | |
5,7,3',5'-tetrahydroxy-6,4'-dimethoxyflavone exhibits anti-HIV-1 activity in the anti-syncytium assay using (∆Tat/rev)MC99 virus and 1A2 cell line system, it shows considerably activity against HIV-1 reverse transcriptas... |
Cat No. | Product Name | Species | Expression System |
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TMPY-01843 | SEMA6A Protein, Human, Recombinant (His) | Human | HEK293 |
SEMA6A, the first identified class 6 semaphorin, is contributed to regulate vascular development and adult angiogenesis. SEMA6A could inhibit proliferation, migration, and invasion in different glioma cell lines. That SE... | |||
TMPJ-01357 | NHP2 Protein, Human, Recombinant (His) | Human | E. coli |
NHP2 belongs to the H/ACA snoRNPs gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been organized into 2 families: C/D and H/ACA. NHP2 forms a small ribonucleoprotein part... | |||
TMPH-02926 | TRET Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic c... | |||
TMPH-02186 | TERT Protein, Human, Recombinant (His) | Human | E. coli |
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic c... | |||
TMPH-01833 | Human Papilloma Virus type 16 (HPV 16) Protein E6 (His) | HPV 16 | Yeast |
Plays a major role in the induction and maintenance of cellular transformation. Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins. E6 associates with host UBE3A/E6-AP ... | |||
TMPH-01832 | Human Papilloma Virus type 16 (HPV 16) Protein E6 (E. coli, His) | HPV 16 | E. coli |
Plays a major role in the induction and maintenance of cellular transformation. Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins. E6 associates with host UBE3A/E6-AP ... | |||
TMPY-01763 | Cadherin 16/CDH16 Protein, Human, Recombinant (His) | Human | HEK293 |
KSP-Cadherin/Cadherin-16 is a member of the cadherin superfamily, calcium-dependent, membrane-associated glycoproteins. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane regio... |
Cat No. | Product Name | ||
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L1720 | Nucleotide Compound Library | 337 compounds | |
A unique collection of 337 nucleoside and nucleotide analogues, can be used for research and development of anti-viral, anti-tumor, anti-fungal, and anti-depressive drugs; |