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Results for "
ide1
" in TargetMol Product Catalog- Inhibitors & Agonists1
- Dye Reagents1
IDE1 
T31621160927-48-9
IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+ FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells (EC50: 125.5 nM in vitro) by activating the TGF-β signaling pathway. IDE1-derived endodermal cells injected into E8.75 mouse embryos ex vivo have been shown to incorporate into the developing gut tube, contributing to its formation.
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