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Results for "

dopamine d2

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    289
    TargetMol | Inhibitors_Agonists
  • Peptide Products
    4
    TargetMol | Peptide_Products
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    8
    TargetMol | Natural_Products
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    1
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    TargetMol | Disease_Modeling_Products
Spiperone
Spiropitan, Spiroperidol
T0280749-02-0
Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
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Dopamine D2 receptor antagonist-1
T110771055411-77-2In house
Dopamine D2 Receptor Antagonist-1 functions as a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R), demonstrating sub-millimolar affinity.
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6-8 weeks
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Dopamine D2 receptor agonist-2
T600751610591-93-9
Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) is a ligand targeting the dopamine D2 receptor.
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ONC206
T163921638178-87-6
ONC206, an analogue of the TRAIL inducer ONC201, acts as a selective antagonist of the D2-like dopamine receptors (DRD2 3 4) at nanomolar concentrations and possesses broad-spectrum anti-tumor activity.
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TargetMol | Inhibitor Hot
5-HT1A modulator 1
5-HT1Amodulator1
T10168142477-34-7In house
5-HT1A modulator 1 exhibits high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM).
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6-8 weeks
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TargetMol | Inhibitor Hot
PF-00217830
PF-217830
T24613846032-02-8In house
PF-00217830 is a serotonin 1A receptor agonist, dopamine D2 receptor agonist, and serotonin 2A receptor antagonist.PF-00217830 may be used in the study of schizophrenia.
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6-8weeks
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A-437203
ABT-925, A37203, Lu201640
T10213220519-06-2In house
A-437203 (Lu201640) is A kind of based on 1 h - pyrimidin - 2 - one sca ff old, selective, new powerful d3 receptor antagonist, on D2, d3, and D4 receptor, Ki value 71, respectively 1.6 and 6220 nM.
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6-8 weeks
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NMI 8739
n-docosahexaenoyl dopamine, Dha-DA conjugate
T11079129024-87-9In house
NMI 8739 (n-docosahexaenoyl dopamine) is an agonist of D2 autoreceptor. NMI 8739 reduces NO production and elicits concentration-dependent suppression of CCL-20, MCP-1 and IL-6 release.
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8-10 weeks
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Sigma-LIGAND-1
T13510139652-01-0In house
Sigma-LIGAND-1 is a selective Sigma Receptor ligand with IC50 values of 16 nM and 19 nM at the DTG site and the PPP site, respectively, and a Ki of 4000 nM at the dopamine D2 receptor.
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6-8 weeks
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SLV-310
SLV310, SLV 310
T28809264869-71-8In house
SLV-310 is a potent dopamine D2 receptor antagonist and 5-HT reuptake receptor inhibitor used in the study of neurological disorders such as bipolar disorder and schizophrenia.
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6-8 weeks
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BL-1020 Mesylate
CYP-1020 Mesylate
T26834916898-61-8In house
BL-1020 Mesylate (CYP-1020 Mesylate) is an orally available GABA A receptor agonist and D2 antagonist that decreases dopamine activity and enhances GABAA activity.BL-1020 Mesylate has been used in the study of schizophrenia, Alzheimer's disease, and bi-directional cognitive impairment.
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6-8 weeks
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5-HT6/7 antagonist 1
T61807131999-28-5In house
5-HT6 7 antagonist 1 is a dual 5-HT6 7 2A and D2 receptor antagonist used in the study of dementia and Alzheimer's disease.
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6-8 weeks
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Lensiprazine
SLV314, SLV-314, SLV 314
T32633327026-93-7In house
Lensiprazine (SLV314) is a potent dopamine D(2) receptor antagonist that acts as a serotonin reuptake inhibitor , and can be used to study bipolar disorder and schizophrenia.
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6-8weeks
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Carmoxirole hydrochloride
EMD 45609 hydrochloride
T10683115092-85-8In house
Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with in vivo antihypertensive activity.
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6-8 weeks
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Abaperidone
T14083183849-43-6In house
Abaperidone is a potent 5-HT2A receptor and dopamine D2 receptor antagonist with an IC50 of 6.2 for 5-HT2A receptors and 17 nM for dopamine D2 receptors.Abaperidone is a potentially atypical anti-psychotropic compound that reduces basal hsp70 mRNA expression in rat striatum and prefrontal cortex. expression in the striatum and prefrontal cortex of rats.
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8-10weeks
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Aplindore Fumarate
DAB-452 Fumarate, DAB452 Fumarate
T30098189681-71-8In house
Aplindore Fumarate (DAB-452) is a small molecule dopamine D2 receptor partial agonist.Aplindore Fumarate exhibits high affinity for dopamine D2 and D3 receptors, and low affinity for dopamine D4, 5-hydroxytryptophan (5-HT2), and α1-adrenergic receptors.Aplindore Fumarate is used in the study of Parkinson's disease and schizophrenia. Fumarate can be used to study Parkinson's and schizophrenia.
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6-8weeks
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A 77636 hydrochloride
A77636 hydrochloride
T21782145307-34-2In house
A 77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM). A 77636 hydrochloride shows antiparkinsonian activity. A 77636 hydrochloride is functionally inactive at dopamine D2 receptor.
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Perphenazine dihydrochloride
T631152015-28-3In house
Perphenazine dihydrochloride is an orally active dopamine receptor and histamine-1 receptor antagonist that acts on D2 (Ki: 0.56 nM), D3 (Ki: 0.43 nM), and 5-HT2A (Ki: 0.6 nM) receptors, and also binds Alpha-1A adrenergic receptors. It can induce apoptosis, inhibit cancer cell proliferation, and is used to study psychiatric disorders, cancer, and inflammation.
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6-8 weeks
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NGD 94-1
T23066178928-68-2In house
NGD 94-1 is a selective D4 receptor antagonist with an affinity of 3 nM for the D4 receptor and greater than 2 pM for the D1, D2, D3, and D5 receptors.NGD 94-1 can be used in the study of cognitive disorders and other psychiatric disorders.
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6-8 weeks
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SKF83959
T6083580751-85-5In house
SKF83959, a benzazepine analog, is a selective and potent partial agonist of the dopamine D1 receptor with Ki values of 1.18, 7.56, 920, and 399 nM for rat D1, D5, D2, and D3 receptors, respectively.SKF83959 is a potent variant modulator of the sigma (σ)-1 receptor, which ameliorates cognitive dysfunction for the study depression and Alzheimer's disease.
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6-8 weeks
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SB-277011
SB-277011A
T12861215803-78-4In house
SB-277011 (SB-277011A) is a specific antagonist of the dopamine D3 receptor with pKi values of 8.0, 6.0, 5.0, and <5.2 for D3 receptor, D2 receptor, 5-HT1D, and 5-HT1B respectively.
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6-8weeks
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JNJ-37822681 dihydrochloride
T117222108806-02-4In house
JNJ-37822681 has potential for the treatment of schizophrenia and bipolar disorder.JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate binding affinity for the dopamine D2
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6-8 weeks
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JNJ-37822681
JNJ37822681, JNJ 37822681
T27677935776-74-2In house
JNJ-37822681 is a novel, highly selective dopamine D₂ receptor antagonist characterized by a rapid dissociation rate from the dopamine D₂ receptor.
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Tiospirone
BMY 13859-1
T2488587691-91-6In house
Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and dopamine blocker that inhibits D2, 5-HT1a, 5-HT7, and sigma receptors.Tiospirone is used in the study of neurological disorders such as schizophrenia.
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6-8 weeks
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