cga

CGA-JK3 is an IkappaB kinase inhibitor in innate immune process.

Triclabendazole (CGA89317) has been used in trials studying Parasitic Disease.

Cyromazine (CGA-72662) is an ectoparasiticide. Insect growth regulator. Specific activity against dipterous larvae. Cyromazine is a fda approved for use in livestock.

Metalaxyl (CGA 48988) is a widely used fungicide that inhibits protein synthesis in fungi, interferes with skeletal development in zebrafish embryos, and can be used to control plant diseases caused by oomycetous fungi.

Fludioxonil (CGA 173506), a phenylpyrrole fungicide, inhibits the growth of B. cinerea from strawberry and blackberry crops.

Pymetrozine (CGA 215944) is a Homoptera feeding inhibitor that effectively prevents transmission of the cauliflower mosaic caulimovirus by the aphid species Myzus persicae.

Trifloxystrobin (CGA 279202) is a fungicide that inhibits the growth of R. solani isolates from sugar beet crops, with EC50 values of 23.0 μg/L for Daphnia magna neonates and 1.7 μg/L for embryos.

Cymiazole is an agent of biochemical.

Propiconazole (PRO) is an orally active brassinosteroid biosynthesis inhibitor and a triazole fungicide with antifungal activity.

Chlorfluazuron, a chitin synthesis inhibitor, is commonly used as an insect growth regulator for controlling the major insect pests in crops.

Dofenapyn (CGA-29170) is an acaricide used for controlling pests in agricultural fields.

Profluralin is a effective herbicide.

Etacelasil (CGA 13586) is a compound that releases ethylene upon contact with water. It facilitates the abscission of olive fruits.

NE97220 is a bioactive chemical.

Nitroscanate is an anthelmintic found to be effective in certain strains of parasites in canines.

3-Aminopropylphosphinic acid (3-APPA), a phosphonic analog of gamma-aminobutyric acid (GABA), acts as a potent and selective agonist of the GABA B receptor.

Fluxofenim (CGA-133205) is an organic chemical compound utilized in the formulation of pesticides.

Trifloxystrobin metabolite CGA-321113 (Standard) is a standard material used for research and analysis of Trifloxystrobin metabolite CGA-321113. It is an acid metabolite of the fungicide trifloxystrobin with antifungal activity.

Fludioxonil is employed to manage the growth of axillary buds (suckers) following the topping of tobacco plants. Its mode of action includes a localized systemic effect, contact action, and phytotoxicity.

2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a second messenger in cellular innate immunity, catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. It binds to STING to form a dimer, inducing the production and expression of interferon-β and other cytokines.

2',3'-cGAMP is an endogenous cyclic dinucleotide (CDN) produced by cGAS (cGAMP synthase) in response to double-stranded DNA in the cytoplasm. It acts as a STING activator and ligand, inducing interferons (IFNs) via the TBK1/IRF3 pathway and pro-inflammatory factors via the NF-κB pathway.

cGAMP is an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. It also is a STING ligand.

cGAMP disodium is a cyclic dinucleotide (CDN) found in bacteria that acts as an endogenous second messenger affecting interferon production in response to cytoplasmic DNA. cGAMP disodium cascades signals from type I interferons and other immune mediators by activating interferon gene stimulator (STING). cGAMP disodium is a potent sublingual immune adjuvant that enables better immune function (serum anti-PA neutralization and airway secretions anti-PA SIgA response).

cGAS-IN-4 (Compound 36) is an orally active inhibitor of cyclic GMP-AMP synthase (cGAS) with IC50 values of 32 nM for human cGAS (h-cGAS) and 5.8 nM for mouse cGAS (m-cGAS). In THP-1 cells, cGAS-IN-4 inhibits cGAMP with an IC50 of 60 nM, enhancing cellular potency. Additionally, cGAS-IN-4 exhibits anti-inflammatory effects in a mouse model of Concanavalin A-induced acute liver injury.