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Search Results for " stem cells "

20

Compounds

Cat No. Product Name Synonyms Targets
T8987 Epiblastin A Casein Kinase
Epiblastin A is an inhibitor of Casein Kinase 1 (CK1). Epiblastin A engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs).
T16695 Pyrintegrin Integrin
Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signal...
T1748 Kartogenin KGN TGF-beta/Smad
Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.
T2040 OAC1 BAS 00287861 OCT
OAC1 (BAS 00287861) is a compound activating Octamer-binding transcription factor 4 (Oct4). It enhances the iPSC reprogramming efficiency and accelerates the reprogramming process.
T0432 Diclofenac diethylamine Apoptosis , COX
Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).
T2161 Cardiogenol C Wnt/beta-catenin
Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.
T2052 KY02111 Wnt/beta-catenin
KY02111 facilitates differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, maybe affect downstream of GSK3β and APC.
T10904 CWP232228 Wnt/beta-catenin
CWP232228, a potent and selective Wnt / β-catenin signaling inhibitor, antagonizes the binding of β-catenin to T-cell factor (TCF) in the nucleus. CWP232228 inhibits the formation and metastasis of tumors by inhibiting t...
T21981 Phthalazinone pyrazole Aurora Kinase
Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity.
T0196 Diclofenac Diclofenacum,Voltaren Apoptosis , COX
Diclofenac (Diclofenacum) is a nonsteroidal benzeneacetic acid derivative with anti-inflammatory activity. Diclofenac binds and chelates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of a...
TN2883 3',4'-Dimethoxyflavone Others , PARP
3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.
T1555 Diclofenac sodium GP 45840 Apoptosis , COX
Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
T6470 Diclofenac Potassium CGP-45840B,Cataflam,Voltfast Apoptosis , Others , COX
Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
T8005 Cardiogenol C hydrochloride Cardiogenol C HCl,Cardiogenol C Wnt/beta-catenin
Cardiogenol C hydrochloride (Cardiogenol C) can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).
T0640 Benzyl butyl phthalate BBP,1,2-benzenedicarboxylic acid,butyl phenylmethyl ester,Butyl benzyl phthalate Others , Aryl Hydrocarbon Receptor
Benzyl butyl phthalate (1,2-benzenedicarboxylic acid) is used as a plasticizer for PVC.
T1048 Estradiol E2,17β-Estradiol,17β-Oestradiol,β-Estradiol Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite
Estradiol (E2) is a naturally occurring steroidal sex hormone that is essential for female fertility and maintenance of secondary sexual characteristics. Estradiol upregulates IL-6 expression through estrogen receptor be...
T3221 Oct3/4-inducer-1 2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile Others , OCT
Oct3/4-inducer-1 (2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile) is an OCT3/4 inducer that promotes the expression and stabilization of OCT3/4 and enhances its transcriptional activity in a variety of human cells.
T1776 Plerixafor JM3100,AMD 3100,AMD-3329 Virus Protease , HIV Protease , CXCR
Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.
TN7036 N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,Macamide Impurity 14 Wnt/beta-catenin
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (Macamide Impurity 14) induces osteogenic differentiation and subsequent bone formation of mesenchymal stem cells by activating the canonical Wnt/β-catenin signaling pa...
T1725 Y-27632 dihydrochloride Y-27632 2HCl ROCK , Apoptosis
Y-27632 dihydrochloride (Y-27632 2HCl) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 dihydrochloride also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells.

Compounds

Epiblastin A
T8987
Synonym:
Target: Casein Kinase
Pyrintegrin
T16695
Synonym:
Target: Integrin
Kartogenin
T1748
Synonym: KGN
Target: TGF-beta/Smad
OAC1
T2040
Synonym: BAS 00287861
Target: OCT
Diclofenac diethylamine
T0432
Synonym:
Target: Apoptosis, COX
Cardiogenol C
T2161
Synonym:
Target: Wnt/beta-catenin
KY02111
T2052
Synonym:
Target: Wnt/beta-catenin
CWP232228
T10904
Synonym:
Target: Wnt/beta-catenin
Phthalazinone pyrazole
T21981
Synonym:
Target: Aurora Kinase
Diclofenac
T0196
Synonym: Diclofenacum,Voltaren
Target: Apoptosis, COX
3',4'-Dimethoxyflavone
TN2883
Synonym:
Target: Others, PARP
Diclofenac sodium
T1555
Synonym: GP 45840
Target: Apoptosis, COX
Diclofenac Potassium
T6470
Synonym: CGP-45840B,Cataflam,Voltfast
Target: Apoptosis, Others, COX
Cardiogenol C hydrochloride
T8005
Synonym: Cardiogenol C HCl,Cardiogenol C
Target: Wnt/beta-catenin
Benzyl butyl phthalate
T0640
Synonym: BBP,1,2-benzenedicarboxylic acid,butyl phenylmethyl ester,Butyl benzyl phthalate
Target: Others, Aryl Hydrocarbon Receptor
Estradiol
T1048
Synonym: E2,17β-Estradiol,17β-Oestradiol,β-Estradiol
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite
Oct3/4-inducer-1
T3221
Synonym: 2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile
Target: Others, OCT
Plerixafor
T1776
Synonym: JM3100,AMD 3100,AMD-3329
Target: Virus Protease, HIV Protease, CXCR
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide
TN7036
Synonym: (9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,Macamide Impurity 14
Target: Wnt/beta-catenin
Y-27632 dihydrochloride
T1725
Synonym: Y-27632 2HCl
Target: ROCK, Apoptosis
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TargetMol