synthetase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T72505	CTP Synthetase-IN-1		Others
	CTP Synthetase-IN-1 is an orally active and potent cytidine 5'-triphosphate synthetase (CTPS) inhibitor with potential antitumour activity, shows anti-inflammatory activity in animal models of inflammation, inhibits huma...		Others
T10303	Aminoacyl tRNA synthetase-IN-1		Others
	Aminoacyl tRNA synthetase-IN-1 is an inhibitor of bacterial aminoacyl tRNA synthetase (aaRS).		Others
T74933	Trypanothione synthetase-IN-2
	Trypanothione Synthetase-IN-2 (Compound 3) functions as a competitive inhibitor of Leishmania infantum trypanothione synthetase (TryS), demonstrating an inhibition constant (IC50) of 5.4 μM in the presence of the polyami...
T76124	Acyl coenzyme A synthetase
	Acyl coenzyme A synthetase (ACS), also known as acetyl coenzyme A synthetase, plays a pivotal role in biochemical research. This enzyme catalyzes the activation of fatty acids via coenzyme A through a two-step thioesteri...
T64056	Trypanothione synthetase-IN-4
	Trypanothione synthetase-IN-4 is a L. infantumTryS inhibitor whose activity is dependent on the concentration of the polyamine substrate. trypanothione synthetase-IN-4 exhibits a strong anti-leishmanicidal effect (EC50: ...
T74934	Trypanothione synthetase-IN-3
	Trypanothione Synthetase-IN-3, a mixed noncompetitive inhibitor of Trypanothione Synthetase (TryS) with an inhibition constant (Ki) of 0.8 μM, is useful in researching parasites like L. infantum [1].
T74932	Trypanothione synthetase-IN-1
	Trypanothione Synthetase-IN-1 (Compound 1) serves as a competitive inhibitor of Leishmania infantum trypanothione synthetase (TryS), demonstrating an IC50 value of 14.8 μM in the presence of the polyamine S, triamine spe...
T63688	Isoleucyl tRNA synthetase-IN-1
	Isoleucyl tRNA synthetase-IN-1 is a selective and potent inhibitor (Ki: 88 nM) that targets isoleucyl tRNA synthetase (IleRS).
T63706	Isoleucyl tRNA synthetase-IN-2
	Isoleucyl tRNA synthetase-IN-2 is a selective and potent inhibitor (Ki: 114 nM) that targets isoleucyl tRNA synthetase (IleRS).
T74612	Aminoacyl tRNA synthetase-IN-2
	Aminoacyl tRNA Synthetase-IN-2 (Compound 14) serves as an inhibitor of aminoacyl-tRNA synthetase (aaRS), presenting potential for the formulation of a novel class of antibiotics [1].
T9533	BC-LI-0186	4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide	Others
	BC-LI-0186 (4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide) is a potent and selective inhibitor of the interaction of Leucyl-tRNA synthetase (LRS) and Ras-related GTP-binding protei...		Others
T11529	H3B-120		Others , Potassium Channel
	H3B-120 is a highly selective, competitive, and allosteric carbamoyl phosphate synthetase 1 (CPS1) inhibitor (IC50: 1.5 μM; Ki: 1.4 μM) with anti-cancer activity.		Others , Potassium Channel
T8356	FPL 62064		Lipoxygenase , COX
	FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin synthetase, respectively).		Lipoxygenase , COX
T0767	Sulfapyridine	Sulfidine,Sulfidin,2-Sulfapyridine	Antibacterial , Antibiotic , Autophagy
	Sulfapyridine (2-Sulfapyridine) is a short-acting sulfonamide antibiotic and by-product of the non-steroidal anti-inflammatory drug sulfasalazine.		Antibacterial , Antibiotic , Autophagy
T33565	NAAD sodium salt	NAAD Na salt,Deamido Nad Sodium Salt,NAAD Na, NaAD
	NAAD sodium salt (NAAD Na salt) is a substrate of nicotinamide adenine dinucleotide synthase and can be used in studies about the specificity and kinetics of the substrate.
T4380	Ac-CoA Synthase Inhibitor1	ACSS2 inhibitor	RSV , Fatty Acid Synthase
	Ac-CoA Synthase Inhibitor1 (ACSS2 inhibitor) is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2).		RSV , Fatty Acid Synthase
T40656	Chlorobenzuron		Others
	Chlorobenzuron is a chitin synthetase inhibitor, acts as an insecticide. Chlorobenzuron inhibits larvae development and pupate.		Others
T6120	Pralatrexate	Folotyn,10-Propargyl-10-deazaaminopterin	Apoptosis , DHFR , Antifolate , TAM Receptor
	Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive act...		Apoptosis , DHFR , Antifolate , TAM Receptor
T0005	Aspirin	Acetylsalicylate,Acetylsalicylic Acid,ASA	Mitophagy , Virus Protease , COX , Autophagy
	Aspirin (Acetylsalicylic Acid) is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Aspirin is a histone deacetylase inhibitors to up-regulate cel...		Mitophagy , Virus Protease , COX , Autophagy
T14141	AGI-24512		Others , Methionine Adenosyltransferase (MAT)
	AGI-24512 is a inhibitor of methionine adenosyltransferase 2A (MATA2 ).It is useful for treatment of cancer and blocks growth of MTAP-deleted cancer cells in vitro.		Others , Methionine Adenosyltransferase (MAT)