dope

DOPE-C8 (1,2-Dioloeoyl-sn-glycero-3-phosphoethanolamine-C8; 1,2-DOPE-C8) is a zwitterionic phospholipid derived from DOPE, utilized for the creation of lipid nanoparticles (LNPs) suitable for in vivo mRNA delivery.

DOPE (DOPE) is a neutral helper lipid for cationic liposomes.It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.

1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)) can be used in lipid mixtures with DOPC and DOPE as effective nontoxic and nonviral DNA vectors. It has been utilized in the formation of unilamellar vesicles to study membrane structure curvature and in supported lipid bilayers to examine the impact of various support materials on lipid redistribution between membrane leaflets.

18:1 PEG350 PE is a PEG lipid functional end group used in synthesizing liposomes (LPs) that is designed for the creation of conjugated polymer nanoparticles. Liposome nanoparticles (LNPs) can couple with other biomolecules through biotin modifications and carboxyl terminals. Functionalized nanoparticles are employed for targeted labeling of specific cell proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles can bind to biotinylated antibodies on cell surface receptors, facilitating fluorescence-based imaging and sensing applications.

18:1 PEG550 PE is utilized as a PEG lipid functional end group for synthesizing liposomes (LPs) and designing conjugated polymer nanoparticles. Liposome nanoparticles (LNPs), featuring biotin modifications and carboxyl terminals, facilitate further coupling with other biomolecules. These functionalized nanoparticles are employed for targeted labeling of specific cellular proteins. Utilizing streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles can bind to biotinylated antibodies on cell surface receptors, enabling fluorescence-based imaging and sensing applications.

18:1 PEG1000 PE is a PEG-lipid functional end group used in the synthesis of liposomes (LPs) and for designing conjugated polymer nanoparticles. Liposome nanoparticles (LNPs) can be further coupled with other biomolecules through biotin modification and a carboxyl end. Functionalized nanoparticles are applicable for the targeted labeling of specific cell proteins. Using streptavidin as a linker, biotin-modified PEG-lipid conjugated polymer nanoparticles can bind with biotinylated antibodies on cell surface receptors, facilitating fluorescence-based imaging and sensing applications.

18:1 PEG3000 PE is a PEG lipid functional terminal group utilized in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Liposome nanoparticles (LNPs), modified with biotin and carboxy terminals, can couple with other biomolecules. Such functionalized nanoparticles are employed for targeted labeling of specific cell proteins. Using streptavidin as a linker, the biotinylated PEG lipid-conjugated polymer nanoparticles can bind with biotinylated antibodies on cell surface receptors, providing utility in fluorescence-based imaging and sensing.

18:1 PEG5000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for designing conjugated polymer nanoparticles. These lipid nanoparticle complexes (LNPs), with biotin modification and carboxyl termini, can further couple with other biomolecules. The functionalized nanoparticles can target and label specific cell proteins. Using streptavidin as a linker, the biotinylated PEG lipid-conjugated polymer nanoparticles can bind to biotinylated antibodies on cell surface receptors, enabling fluorescence-based imaging and sensing applications.

18:1 Glutaryl PE monosodium is a functionalized lipid.

18:1 PE (DOPE) pSar25 is a derivative of polyethylene glycol, suitable for use in liposome and lipid nanoparticle delivery systems.

Se-DOPE is a selenium-containing phospholipid molecule utilized for the synthesis of bifunctional Janus lipase. It facilitates the production of ROS under light induction and scavenges ROS in the presence of glutathione. Se-DOPE plays a role in regulating redox and immune homeostasis, aiding in the healing of infectious diabetic wounds.

DOPE-GA is a chemical compound utilized in the formulation of liposomes for drug delivery research [1].

DOPE-NHS is a linker useful for conjugating peptides to exosomes and potentially other membrane-based nanoparticles for drug delivery [1].

DOPE-mPEG (MW 2000), a polydisperse phospholipid PEG (or DOPE liposome), facilitates the targeted delivery of liposomal drugs and the formation of giant unilamellar vesicles (GUVs). Its presence notably diminishes the liposome's pH-sensitivity in a concentration-dependent manner [1] [2] [3].

DOPE-PEG-DBCO (MW 2000) is a PEG lipid featuring DOPE and DBCO as functional groups. DOPE serves as a helper lipid in gene transfection, PEG is utilized in drug delivery systems, and DBCO is applicable in click chemistry.

DOPE-PEG-BDP FL, MW 5000 is a PEG-lipid-dye conjugate composed of an unsaturated phospholipid, DOPE, a BDP FL fluorophore with excitation and emission maxima at 504 nm and 514 nm, respectively, and a large PEG spacer that links the phospholipid and fluorophore.

DOPE-PEG-Fluor 647, MW 2000, is a PEG-lipid-dye conjugate consisting of a DOPE phospholipid and a Fluor 647 fluorescent dye.

DOPE-PEG-FITC (MW 2000) is a phospholipid known for its excellent biocompatibility and significant amphiphilic properties, making it a primary and suitable excipient or formulation in drug delivery systems for enhanced therapeutic outcomes. Additionally, DOPE-PEG-FITC (MW 2000) is useful in research focused on drug delivery mechanisms.

DOPE-PEG-Azide (MW 1000) is a phospholipid known for its excellent biocompatibility and significant amphiphilic properties, making it a primary and suitable formulating agent or excipient in drug formulations for enhanced therapeutic outcomes. It is utilized in research focused on drug delivery.

DOPE-PEG-Azide (MW 3400) is a phospholipid known for its excellent biocompatibility and pronounced amphiphilic properties, making it a key and suitable excipient or formulation in drug delivery systems for enhanced therapeutic outcomes. It is utilized in research focused on drug delivery.

DOPE-PEG-Azide (MW 5000) is a phospholipid known for its excellent biocompatibility and notable amphiphilic properties, making it an ideal component as a formulation type or excipient in pharmaceuticals for enhanced therapeutic outcomes. It is utilized in drug delivery research.

DOPE-PEG-Fluor 488, MW 2000, is a lipid conjugated with polyethylene glycol, featuring a DOPE group and a Fluor 488 fluorescent group. DOPE is an unsaturated phospholipid. Fluor 488 has excitation and emission maxima at 499 nm and 520 nm, respectively.

DOPE-PEG-Fluor 488, MW 5000, is a lipid compound of the PEG class, consisting of a DOPE phospholipid and a Fluor 488 fluorescent dye.

DOPE-PEG-Fluor 555, MW 2000, is a PEG-lipid-dye conjugate composed of DOPE phospholipid and Fluor 555 dye. DOPE serves as a neutral helper lipid in cationic liposomes, while Fluor 555 is a fluorescent dye.