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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9919 | Alemtuzumab | Others | |
Alemtuzumab is a humanized monoclonal antibody against CD52 an antigen found on the surface of normal and malignant lymphocytes. | |||
T9616 | PD-1/PD-L1-IN-10 | PD-1/PD-L1 | |
PD-1/PD-L1-IN-10 is an orally active PD-1/PD-L1 inhibitor (IC50 of 2.7 nM) with potent anticancer efficacy. | |||
T10389L | Aspartyl-alanyl-diketopiperazine acetate | DA-DKP,Aspartyl-alanyl-diketopiperazine acetate(110954-19-3 Free base) | Others |
Aspartyl-alanyl-diketopiperazine acetate (DA-DKP) (DA-DKP) can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy. | |||
T3977 | Lifitegrast | SHP-606,SAR 1118 | Integrin |
Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist. | |||
TQ0007 | Cintirorgon | LYC-55716 | ROR |
Cintirorgon (LYC-55716) is a selective, oral agonist of RORγ. Cintirorgon modulates gene expression of RORγ expressing T lymphocyte immune cells. | |||
T77466 | Tremelimumab | Ticilimumab,CP-675206 | Others |
Tremelimumab is a cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) blocking antibody.Tremelimumab is often used in combination with Durvalumab for the treatment of solid cancers such as hepatocellular carcinoma and l... | |||
T20879 | Tacrolimus monohydrate | FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,FK 506 | Phosphatase , Others , Antibacterial , Antibiotic , Autophagy |
Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, whi... | |||
T0944 | Levamisole hydrochloride | (-)-Tetramisole hydrochloride | Phospholipase , AChR , Parasite , HSV |
Levamisole hydrochloride ((-)-Tetramisole hydrochloride) is an antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemo... | |||
T63790 | Cbl-b-IN-3 | E1/E2/E3 Enzyme | |
Cbl-b-IN-3 is a potent proto-oncogene-B (CPL-B) inhibitor of casitas B-series lymphoma (ic50 < 1 nM). Cpl-b, a cyclic E3 ubiquitin protein ligase, is involved in the setting of T lymphocyte activation thresholds. Cpl-b n... | |||
T3614 | Inosine pranobex | Groprinosin,Isoprinosine,Immunovir,Delimmun | IL Receptor , HIV Protease |
Inosine pranobex (Delimmun) has a number of immunomodulatory effects, including inducing T-lymphocyte differentiation, augmenting macrophage and NK cell functions, and stimulating IL-2 production. Through these effects a... | |||
T1257 | Bestatin | Ubenimex | Others , Aminopeptidase , Antibacterial , Antibiotic , LTR |
Bestatin (Ubenimex) competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Amin... | |||
T26752 | BC12 | BC 12,BC-12 | |
BC12 exhibits unusually potent immunomodulatory actions on T lymphocyte function, including inhibition of T cell proliferation and IL-2 cytokine production. | |||
TP1612 | OVA sequence (323-336) | OVA sequence 323-336 | |
This peptide is a cognate helper T-lymphocyte peptide that is employed to enhance CTL epitope immunogencity | |||
T77103 | Nurulimab | ||
Nurulimab (BCD-145) is a humanized monoclonal antibody targeting cytotoxic T lymphocyte antigen-4 (anti-CTLA-4). It has potential applications in melanoma research [1]. | |||
T3977L | Lifitegrast sodium | SAR-1118-023,SAR1118-023,SAR 1118-023,Xiidra | |
Lifitegrast sodium (SAR-1118) is an LFA-1 antagonist for the therapy of vascular complications of the eye. It inhibits T cell-mediated inflammation by blocking the binding of two cell surface proteins (lymphocyte functio... | |||
TP1515 | HPV16-E711-20 epitope | ||
HPV16-E711-20 epitope is a well-known HLA-A*0201-restricted human cytotoxic T lymphocyte (CTL) epitope of the HPV16 E7 protein that shows high-affinity binding to HLA-A2 in vitro. | |||
T82743 | CFP10 (71–85) | ||
CFP10 (71–85) is an immunologically active peptide that induces IFN-γ production and cytotoxic T lymphocyte (CTL) activity in CD4+ and CD8+ T cells from individuals with diverse MHC class II and I expression profiles. | |||
T39292 | NS2 (114-121), Influenza | NS2 (114-121), Influenza | |
NS2 (114-121), Influenza, is a fragment derived from the nonstructural protein 2 (NS2) of the influenza virus. This compound serves as an epitope for influenza research and can be utilized to study the CD8+ cytotoxic T l... | |||
T80573 | Firastotug | ||
Firastotug, an IgG1κ antibody, targets CTLA4, a cytotoxic T lymphocyte-associated protein that serves as a crucial immune checkpoint in autoimmunity and cancer [1]. | |||
T27192 | DMI-9523 | DA-DKP,Ampion,DMI 9523,DM-9523 | |
DMI-9523 is nuclear factor NF-κB activation inhibitor. Antigen-stimulated human T lymphocytes produce significantly lower quantities of interferon-gamma and tumor necrosis factor-alpha after stimulation in vitro in the p... |