T29968 |
AMG-0347
|
946615-43-6
|
98%
|
|
AMG-0347 is a small molecule inhibitor targeting TRPA1(transient receptor potential ankyrin 1) ion channels, a receptor found in sensory neurons and involved in ...
|
T70540 |
Pinokalant
|
149759-26-2
|
98%
|
|
Pinokalant is a novel non-selective cation channel inhibitor.Pinokalant significantly reduces cortical infarct volume in in vivo experiments, improves the metabo...
|
T41233 |
Cis-22a
|
1819366-84-1
|
98%
|
|
Cis-22a is a TRPV6 inhibitor (IC50 = 0.32 μM), which exhibits selectivity against related TRPV channels and calcium channels. cis-22a displays antiproliferative ...
|
T14087 |
ABT-239
|
460746-46-7
|
98%
|
|
ABT-239 is a novel, highly efficacious, non-imidazole class of H3R antagonist. Its a transient receptor potential vanilloid type 1 (TRPV1) antagonist.
|
T5786 |
TETRAHYDROPIPERINE
|
23434-88-0
|
98%
|
|
TETRAHYDROPIPERINE is a natural product derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects.
|
T61275 |
TRPM4-IN-2
|
667411-04-3
|
98%
|
|
TRPM4-IN-2, also known as NBA, is a highly effective inhibitor of transient receptor potential melastatin 4 (TRPM4). Its inhibitory potency is represented by an ...
|
T11172 |
EIPA hydrochloride
|
1345839-28-2
|
98%
|
|
EIPA hydrochloride also inhibits Na+/H+-exchanger (NHE) and macropinocytosisEIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel inhibitor with an IC50 ...
|
T15439 |
GSK3395879
|
2215852-91-6
|
98%
|
|
GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4).
|
T37697L |
D-GsMTx4 TFA
|
|
98%
|
|
D-GsMTx4 TFA, a selective spider venom peptide, is a TRPC1/6 and Piezo2 inhibitor that inhibits cation-permeable mechanosensitive channels (MSCs) belonging to th...
|
TN1583 |
Dihydromorin
|
18422-83-8
|
98%
|
|
trans-Dihydromorin is an effective hypopigmenting agent in normal skin cells, hypopigmenting agents effective in melanoma system may not be effective on normal m...
|
T15434 |
GSK2798745
|
1419609-94-1
|
98%
|
|
GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: 1.8 and 1.6 nM for hTRPV4 and rTRPV4). It is used in ...
|
T15634 |
JYL 1421
|
401907-26-4
|
98%
|
|
JYL 1421 is an antagonist of TRPV1 receptor (IC50 = 8 nM).
|
TN2429 |
Capsiate
|
205687-01-0
|
98%
|
|
Capsiate is an orally active TRPV1 agonist, a non-irritating capsaicin analog that acts as an antiallergic agent with anti-inflammatory, antioxidant, hypoglycemi...
|
T13214 |
TRPV4 agonist-1
|
2314467-60-0
|
98%
|
|
TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).
|
T13212 |
TRPA1 Antagonist 1
|
1984825-08-2
|
98%
|
|
TRPA1 Antagonist 1 is an antagonist of TRPA1(IC50: 8 nM) and is a methylene phosphate prodrug which converts to its active parent drug.
|
T13546 |
AM12
|
2387510-84-9
|
98%
|
|
AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM).
|
T14067 |
A-1165442
|
1221443-94-2
|
98%
|
|
A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.
|
T2807 |
Caffeic Acid
|
331-39-5
|
98%
|
|
Caffeic Acid is an orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant, anti-inflammatory, and antineoplastic activi...
|
T2298 |
ML204
|
5465-86-1
|
98%
|
|
ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
|
T21623 |
AS1269574
|
330981-72-1
|
98%
|
|
AS 1269574 is a potent, orally available GPR119 agonist. AS1269574 has the potential for the research of type 2 diabetes.
|