TRP/TRPV Channel

TRPV is a family of transient receptor potential cation channels (TRP channels) in animals. All TRPVs are highly calcium selective. TRP channels are a large group of ion channels consisting of six protein families, located mostly on the plasma membrane of numerous human and animal cell types, and in some fungi.

Cat. No.	Product name	CAS No.	Purity
T61275	TRPM4-IN-2	667411-04-3	100%
T61275	TRPM4-IN-2, also known as NBA, is a highly effective inhibitor of transient receptor potential melastatin 4 (TRPM4). Its inhibitory potency is represented by an ...
T11172	EIPA hydrochloride	1345839-28-2	98%
T11172	EIPA hydrochloride also inhibits Na+/H+-exchanger (NHE) and macropinocytosisEIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel inhibitor with an IC50 ...
T15439	GSK3395879	2215852-91-6	98%
T15439	GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4).
T37697L	D-GsMTx4 TFA		98%
T37697L	D-GsMTx4 TFA, a selective spider venom peptide, is a TRPC1/6 and Piezo2 inhibitor that inhibits cation-permeable mechanosensitive channels (MSCs) belonging to th...
TN1583	Dihydromorin	18422-83-8	98%
TN1583	trans-Dihydromorin is an effective hypopigmenting agent in normal skin cells, hypopigmenting agents effective in melanoma system may not be effective on normal m...
T15434	GSK2798745	1419609-94-1	98%
T15434	GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: 1.8 and 1.6 nM for hTRPV4 and rTRPV4). It is used in ...
T15634	JYL 1421	401907-26-4	98%
T15634	JYL 1421 is an antagonist of TRPV1 receptor (IC50 = 8 nM).
TN2429	Capsiate	205687-01-0	98%
TN2429	Capsiate is an orally active TRPV1 agonist, a non-irritating capsaicin analog that acts as an antiallergic agent with anti-inflammatory, antioxidant, hypoglycemi...
T13214	TRPV4 agonist-1	2314467-60-0	98%
T13214	TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).
T13212	TRPA1 Antagonist 1	1984825-08-2	98%
T13212	TRPA1 Antagonist 1 is an antagonist of TRPA1(IC50: 8 nM) and is a methylene phosphate prodrug which converts to its active parent drug.
T13546	AM12	2387510-84-9	98%
T13546	AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM).
T14067	A-1165442	1221443-94-2	98%
T14067	A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.
T2807	Caffeic Acid	331-39-5	99.99%
T2807	Caffeic Acid is an orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant, anti-inflammatory, and antineoplastic activi...
T2298	ML204	5465-86-1	99.98%
T2298	ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
T21623	AS1269574	330981-72-1	99.98%
T21623	AS 1269574 is a potent, orally available GPR119 agonist. AS1269574 has the potential for the research of type 2 diabetes.
T22360	MDR-652	1933528-96-1	99.96%
T22360	MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 (TRPV1) with Ki value of 11.4 nM and 23.8 nM for hTRP...
T7526	JNJ-17203212	821768-06-3	99.94%
T7526	JNJ-17203212 is a potent and selective antagonist of TRPV1 (human TRPV1 and rat TRPV1, IC50 of 65 nM and 102 nM).
T21165	Pellitorine	18836-52-7	99.94%
T21165	Pellitorine is an extract of Tetradium daniellii, and acts as a TRPV1 antagonist.
T15758	Linopirdine	105431-72-9	99.92%
T15758	Linopirdine is a TRPV1 agonist. Linopirdine is an orally active and selective M-type K+ current (IM; Kv7; KCNQ Channels) inhibitor (IC50: 2.4 μM). Linopirdine is...
T10929L	D-3263 hydrochloride	1008763-54-9	99.85%
T10929L	D-3263 hydrochloride is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.