T61275 |
TRPM4-IN-2
|
667411-04-3
|
100%
|
|
TRPM4-IN-2, also known as NBA, is a highly effective inhibitor of transient receptor potential melastatin 4 (TRPM4). Its inhibitory potency is represented by an ...
|
T11172 |
EIPA hydrochloride
|
1345839-28-2
|
98%
|
|
EIPA hydrochloride also inhibits Na+/H+-exchanger (NHE) and macropinocytosisEIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel inhibitor with an IC50 ...
|
T15439 |
GSK3395879
|
2215852-91-6
|
98%
|
|
GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4).
|
T37697L |
D-GsMTx4 TFA
|
|
98%
|
|
D-GsMTx4 TFA, a selective spider venom peptide, is a TRPC1/6 and Piezo2 inhibitor that inhibits cation-permeable mechanosensitive channels (MSCs) belonging to th...
|
TN1583 |
Dihydromorin
|
18422-83-8
|
98%
|
|
trans-Dihydromorin is an effective hypopigmenting agent in normal skin cells, hypopigmenting agents effective in melanoma system may not be effective on normal m...
|
T15434 |
GSK2798745
|
1419609-94-1
|
98%
|
|
GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: 1.8 and 1.6 nM for hTRPV4 and rTRPV4). It is used in ...
|
T15634 |
JYL 1421
|
401907-26-4
|
98%
|
|
JYL 1421 is an antagonist of TRPV1 receptor (IC50 = 8 nM).
|
TN2429 |
Capsiate
|
205687-01-0
|
98%
|
|
Capsiate is an orally active TRPV1 agonist, a non-irritating capsaicin analog that acts as an antiallergic agent with anti-inflammatory, antioxidant, hypoglycemi...
|
T13214 |
TRPV4 agonist-1
|
2314467-60-0
|
98%
|
|
TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).
|
T13212 |
TRPA1 Antagonist 1
|
1984825-08-2
|
98%
|
|
TRPA1 Antagonist 1 is an antagonist of TRPA1(IC50: 8 nM) and is a methylene phosphate prodrug which converts to its active parent drug.
|
T13546 |
AM12
|
2387510-84-9
|
98%
|
|
AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM).
|
T14067 |
A-1165442
|
1221443-94-2
|
98%
|
|
A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.
|
T2807 |
Caffeic Acid
|
331-39-5
|
99.99%
|
|
Caffeic Acid is an orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant, anti-inflammatory, and antineoplastic activi...
|
T2298 |
ML204
|
5465-86-1
|
99.98%
|
|
ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
|
T21623 |
AS1269574
|
330981-72-1
|
99.98%
|
|
AS 1269574 is a potent, orally available GPR119 agonist. AS1269574 has the potential for the research of type 2 diabetes.
|
T22360 |
MDR-652
|
1933528-96-1
|
99.96%
|
|
MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 (TRPV1) with Ki value of 11.4 nM and 23.8 nM for hTRP...
|
T7526 |
JNJ-17203212
|
821768-06-3
|
99.94%
|
|
JNJ-17203212 is a potent and selective antagonist of TRPV1 (human TRPV1 and rat TRPV1, IC50 of 65 nM and 102 nM).
|
T21165 |
Pellitorine
|
18836-52-7
|
99.94%
|
|
Pellitorine is an extract of Tetradium daniellii, and acts as a TRPV1 antagonist.
|
T15758 |
Linopirdine
|
105431-72-9
|
99.92%
|
|
Linopirdine is a TRPV1 agonist. Linopirdine is an orally active and selective M-type K+ current (IM; Kv7; KCNQ Channels) inhibitor (IC50: 2.4 μM). Linopirdine is...
|
T10929L |
D-3263 hydrochloride
|
1008763-54-9
|
99.85%
|
|
D-3263 hydrochloride is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.
|