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Search Results for " pdi "

19

Compounds

Cat No. Product Name Synonyms Targets
T24608 PDI-IN-P1 PDI inhibitor P1,PDIINP1,PDI-inhibitor-P1
PDI-IN-P1 is an inhibitor of protein disulfide isomerase.
T25821 ML359 ML-359,ML 359 Others
ML359 is a protein disulfide isomerase inhibitor.
T6800 CCF642 AC1LYELL Others
CCF642 (AC1LYELL) is a novel PDI-inhibiting compound with antimyeloma activity.
T8640 G6PDi-1 Dehydrogenase
G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production.
T4S1057 Tripdiolide IL Receptor , TNF
Tripdiolide has cytotoxic, and anti-rheumatic activities, it suppresses pro-inflammatory gene expression, may be effective therapy for lupus nephritis.
T30473 Bis-hema ipdi
Bis-hema ipdi is a bioactive chemical.
T5453 3-Methyltoxoflavin 3-methyl toxoflavin Others
3-Methyltoxoflavin (3-methyl toxoflavin) is an effective inhibitor of protein disulfide isomerase (PDI) and its IC50 value is 170 nM.
T5534 LOC14 Others
LOC14 to be the most potent PDI inhibitor reported to date( EC50 : 500 nM)
T41277 PACMA 31 Others
PACMA 31 is an irreversible and covalent inhibitor of protein disulfide isomerase (PDI) with an IC50 of 10 μM. PACMA 31 significantly suppresses ovarian tumor growth and exhibits tumor targeting ability.
T11141 E64FC26 Others
E64FC26 is a potent protein disulfide isomerase (PDI) family pan-inhibitor with antitumor activity, inhibits PDIA1, PDIA3, PDIA4, TXNDC5 and PDIA6, and can be used in the study of multiple myeloma and pancreatic cancer.
T3752 4-Hydroxybenzyl alcohol 4-Methylolphenol,P-Methylolphenol Apoptosis , Endogenous Metabolite
4-Hydroxybenzyl alcohol (P-Methylolphenol) exhibits beneficial effects in cerebral ischemic injury, has neuroprotective effect through upregulation of Nrf2, Prdx6, and PDI expression via the PI3K/Akt pathway. 4-Hydroxybe...
T71589 AS15
AS15 is a novel covalent nanomolar inhibitor of protein disulfide isomerase (PDI).
T69700 BAP2
BAP2 is a novel inhibitor of protein disulfide isomerase (PDI).
T19505 PBDB-T Others
PBDB-T serves as a wide-bandgap polymer donor within polymer solar cells that utilize Perylene Diimide (PDI) as the base.
T69718 Bacitracin F
Bacitracin F is a major Bacitracin analog -- a peptide antibiotic used as an inhibitor of protein disulfide isomerase (PDI).
T35608 16F16
16F16 is a protein disulfide isomerase (PDI) inhibitor.1It inhibits PDI reductase activity in an enzyme assay when used at concentrations ranging from 1 to 100 μg/ml.116F16 reduces PC12 cell apoptosis induced by the misf...
T74207 Ribostamycin
Ribostamycin (Vistamycin), a broad-spectrum aminoglycoside antibiotic, demonstrates efficacy against both Gram-Negative and Gram-Positive bacterial infections. Additionally, it inhibits the chaperone activity of PDI [1] ...
T82003 Juniferdin
Juniferdin, a Protein disulfide isomerase (PDI) inhibitor with an IC50 of 3.5 μM, is designed to prevent HIV transmission. It exhibits cytotoxic properties and inhibits platelet aggregation [1].
T39812 (E/Z)-E64FC26 (E/Z)-E64FC26
(E/Z)-E64FC26 is a mixture complex comprising E-E64FC26 and Z-E64FC26. E-E64FC26 is a highly potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC50 values of 1.9, 20.9, 25.9, 16.3, and 25.4 μM ag...
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