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Microtubule Associated

Microtubule-associated proteins (MAPs) are proteins that interact with the microtubules of the cellular cytoskeleton. MAPs bind to the tubulin subunits that make up microtubules to regulate their stability. A large variety of MAPs have been identified in many different cell types, and they have been found to carry out a wide range of functions. These include both stabilizing and destabilizing microtubules, guiding microtubules towards specific cellular locations, cross-linking microtubules and mediating the interactions of microtubules with other proteins in the cell.
Cat. No. Product name CAS No. Purity Chemical Structure
T13225 Tubulin inhibitor 7 1309925-41-4 98%
Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (IC...
TQ0141 Taltobulin 228266-40-8 98%
Taltobulin (HTI-286) is a potent tubulin inhibitor.
T13226 Tubulin inhibitor 8 1309925-39-0 98%
Tubulin inhibitor 8 is an inhibitor of tubulin and multiple cancer cell lines (tubulin polymerization with an IC50 of 0.73 μM, K562 cell growth with an IC50 of 1...
TQ0112 Tubulysin A 205304-86-5 98%
Tubulysin A is a natural product from myxobacterial. It has many function in vitro assays, including anti-microtubule, anti-mitotic, an apoptosis inducer, antica...
T12052 Mivobulin 122332-18-7 98%
Mivobulin is an inhibitor of tubulin .
T6721 Vinblastine 865-21-4 98%
Vinblastine inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 μM, used to treat certain kinds of cancer.
T16386 Ombrabulin hydrochloride 253426-24-3 98%
Ombrabulin hydrochloride is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of ...
T10428 AZ82 1449578-65-7 98%
AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor (Ki: 43 nM; IC50: 300 nM for KIFC1).
TQ0202 Epothilone D 189453-10-9 98%
Epothilone D (KOS 862) is an effective microtubule stabilizer.
T6722 Vinflunine Tartrate 1201898-17-0 98%
Vinflunine Tartrat is a vinca alkaloid uniquely fluorinated with the properties of mitotic-arresting and tubulin-interacting activity.
T12823 S516 1016543-77-3 98%
S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.
T16387 Ombrabulin 181816-48-8 98%
Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial ce...
T16543 Pironetin 151519-02-7 98%
Pironetin binds to α-tubulin and is an effective inhibitor of microtubule polymerization. It also has cell cycle arrest and antitumor activity. Pironetin is an α...
T17229 Verubulin 827031-83-4 98%
Verubulin is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities.
T23889 CID-663143 578723-96-3 98%
CID-663143 inhibits cancer cell growth and shows microtubule-binding activity.
T13901 SS28 141172-08-9 98%
SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.
T22262 Ansamitocin p-3 66584-72-3 98%
Ansamitocin p-3 is an inhibitor of microtubule with IC50 of 3.4 μM for tubulin polymerization.
T12805 S-methyl DM1 912569-84-7 98%
S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.
T16997 Tasidotin hydrochloride 623174-20-9 98%
Tasidotin hydrochloride is a peptide analog of the antimitotic depsipeptide dolastatin 15. Tasidotin hydrochloride is an inhibitor of microtubule assembly and mi...
T13807 OSIP-486823 200803-37-8 98%
OSIP-486823 is a microtubule-interfering agent with distinct biological effects on both protein kinase G (PKG) and microtubules.
Tubulin inhibitor 7
T13225
Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (IC...
Taltobulin
TQ0141
Taltobulin (HTI-286) is a potent tubulin inhibitor.
Tubulin inhibitor 8
T13226
Tubulin inhibitor 8 is an inhibitor of tubulin and multiple cancer cell lines (tubulin polymerization with an IC50 of 0.73 μM, K562 cell growth with an IC50 of 1...
Tubulysin A
TQ0112
Tubulysin A is a natural product from myxobacterial. It has many function in vitro assays, including anti-microtubule, anti-mitotic, an apoptosis inducer, antica...
Mivobulin
T12052
Mivobulin is an inhibitor of tubulin .
Vinblastine
T6721
Vinblastine inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 μM, used to treat certain kinds of cancer.
Ombrabulin hydrochloride
T16386
Ombrabulin hydrochloride is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of ...
AZ82
T10428
AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor (Ki: 43 nM; IC50: 300 nM for KIFC1).
Epothilone D
TQ0202
Epothilone D (KOS 862) is an effective microtubule stabilizer.
Vinflunine Tartrate
T6722
Vinflunine Tartrat is a vinca alkaloid uniquely fluorinated with the properties of mitotic-arresting and tubulin-interacting activity.
S516
T12823
S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.
Ombrabulin
T16387
Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial ce...
Pironetin
T16543
Pironetin binds to α-tubulin and is an effective inhibitor of microtubule polymerization. It also has cell cycle arrest and antitumor activity. Pironetin is an α...
Verubulin
T17229
Verubulin is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities.
CID-663143
T23889
CID-663143 inhibits cancer cell growth and shows microtubule-binding activity.
SS28
T13901
SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.
Ansamitocin p-3
T22262
Ansamitocin p-3 is an inhibitor of microtubule with IC50 of 3.4 μM for tubulin polymerization.
S-methyl DM1
T12805
S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.
Tasidotin hydrochloride
T16997
Tasidotin hydrochloride is a peptide analog of the antimitotic depsipeptide dolastatin 15. Tasidotin hydrochloride is an inhibitor of microtubule assembly and mi...
OSIP-486823
T13807
OSIP-486823 is a microtubule-interfering agent with distinct biological effects on both protein kinase G (PKG) and microtubules.
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