T60082 |
HDAC-IN-40
|
2463198-51-6
|
98%
|
|
HDAC-IN-40 is a potent alkoxyamide-based HDAC inhibitor with Ki of 60 nM and 30 nM for HDAC2 and HDAC6, respectively. HDAC-IN-40 had antitumor effects
|
T67878 |
HDAC-IN-52
|
2075787-77-6
|
98%
|
|
HDAC-IN-52 is a pyridine-containing HDAC inhibitor that inhibits HDAC1, HDAC2, HDAC3 and HDAC10 with IC50s of 0.189, 0.227, 0.440 and 0.446 μM, respectively. HDA...
|
T69735 |
ITF3756
|
2247608-27-9
|
98%
|
|
ITF3756 is a selective HDAC6 inhibitor.
|
T73181 |
HDAC-IN-51
|
|
98%
|
|
HDAC-IN-51 is an HDAC inhibitor.
|
T77334 |
HDAC-IN-57
|
2716217-79-5
|
98%
|
|
HDAC-IN-57 is an orally active pan-inhibitor of histone deacetylase (HDAC), inhibiting HDAC1, HDAC2, HDAC6, and HDAC8 with IC50 values of 2.07 nM, 4.71 nM, 2.4 n...
|
T10883L |
CRA-026440 hydrochloride
|
847459-98-7
|
98%
|
|
CRA-026440 hydrochloride is a potent and broad-spectrum HDAC inhibitor. CRA-026440 hydrochloride exhibits Ki values against recombinant HDAC isoenzymes HDAC1, HD...
|
T25175 |
BRD 9757
|
1423058-85-8
|
98%
|
|
BRD 9757 is a selective inhibitor of HDAC6 (IC50 = 30 nM).
|
T30579 |
BRD4097
|
1550053-19-4
|
98%
|
|
BRD4097, a negative control in the HDAC1/2/3/8 assay, is a selective histone deacetylase (HDAC3) inhibitor that can be used to protect b-cells and improve insuli...
|
T24133 |
HDAC8-IN-20a
|
1884231-52-0
|
98%
|
|
HDAC8-IN-20a is a potent and selective HDAC8 inhibitor with an IC50 of 27 nM. HDAC8-IN-20a blocks activation of growth receptor survival signals.
|
T10864 |
Corin
|
1808113-09-8
|
98%
|
|
Corin is an irreversible inhibitor of HDAC1(IC50 = 147 nM) and LSD1(Ki = 110 nM).
|
T27083 |
Crebinostat
|
1092061-61-4
|
98%
|
|
Crebinostat is a potent histone deacetylase (HDAC) inhibitor, inhibiting HDAC1, HDAC2, HDAC3, and HDAC6 with IC50s of 0.7 nM, 1.0 nM, 2.0 nM, and 9.3 nM, respect...
|
T14947 |
CHDI-390576
|
1629729-98-1
|
98%
|
|
CHDI-390576 is a CNS penetrant class IIa HDAC inhibitor (IC50s: 54 nM, 60 nM, 31 nM, 50 nM for class IIa HDAC4, HDAC5, HDAC7, HDAC9). It shows >500-fold selectiv...
|
T14936 |
Ivaltinostat
|
936221-33-9
|
98%
|
|
CG-200745 is a potent inhibitor of HDAC. CG200745 induces apoptosis and also inhibits the deacetylation of histone H3 and tubulin.
|
T11542 |
HDAC-IN-4
|
1252003-13-6
|
98%
|
|
HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor (pIC50s: 7.2 and 6.8 in BRET assay) with antitumoral activity.
|
T10602 |
BRD 4354 ditrifluoroacetate
|
T10602
|
98%
|
|
BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9 (IC50s: 0.85 and 1.88 μM).
|
T2S0606 |
Bakkenolide A
|
19906-72-0
|
98%
|
|
Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related sign...
|
T11543 |
HDAC-IN-5
|
1314890-51-1
|
98%
|
|
HDAC-IN-5 is a histone deacetylase (HDAC) inhibitor.
|
T11544 |
HDACs/mTOR Inhibitor 1
|
2271413-06-8
|
98%
|
|
HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM, 1...
|
T14305 |
Apicidin
|
183506-66-3
|
98%
|
|
Apicidin (OSI 2040) is a fungal metabolite, acts as a histone deacetylase (HDAC) inhibitor. It has antiparasitic activity and a broad spectrum antiproliferative ...
|
T10883 |
CRA-026440
|
847460-34-8
|
98%
|
|
CRA-026440 is a potent, broad-spectrum HDAC inhibitor (Kis: 4, 14, 11, 15, 7, and 20 nM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10).
|