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MDK5466 is an Flt3 inhibitor that acts by preventing glutamate-induced cell death.

E3 Ligase Ligand 21 (compound 2), a cereblon binder, facilitates the degradation of Ikaros or Aiolos via the ubiquitin proteasome pathway [1].

6α-Methylprednisolone 21-hemisuccinate sodium salt (Asmacortone), a water-soluble ester, is used for allergic, cardiac, and hypoxic emergencies.

Flumethasone 21-acetate is an anti-inflammatory corticosteroid.

Fce 21258 is used to stimulate the adenylate cyclase of synovial fluid macrophages.

Aldosterone 21-sulfate sodium salt is a cholesterol metabolite discovered in urine.

Prednisone 21-aldehyde is a derivative of the synthetic corticosteroid prednisone that has antiviral activity against influenza virus A-PR8 in embryonated chicken eggs. 22-hydroxy Prednisone is an unstable adduct of prednisone. It has been observed following incubation of prednisone with nornicotine. This product is a mixture of prednisone 21-aldehyde and 22-hydroxy prednisone.

Betamethasone 21-phosphate is a synthetic glucocorticoid.1It prevents increases in macrophage and eosinophil numbers in bronchoalveolar lavage fluid (BALF) and decreases in blood leukocyte numbers in a guinea pig model of parainfluenza-3 viral infection when administered at a dose of 8 mg/kg but does not prevent airway hyperresponsiveness after infection.2Betamethasone 21-phosphate inhibits cell infiltration into the aqueous humor in a rat model of endotoxin-induced uveitis when administered topically or subcutaneously at doses of 0.01-1% or 1 mg/kg, respectively.3It increases maximal lung pressure volume curves in fetal sheep when administered to pregnant ewes at 0.75 gestation at doses of 80 and 170 μg/kg.1Betamethasone 21-phosphate increases body weight, impairs learning and memory, increases anxiolytic behavior, and reduces hippocampal neurogenesis in CD-1 mice but reduces body weight and increases neurogenesis with no effect on anxiety in high-anxiety DBA/2 mice when administered at a dose of approximately 25 mg/kg per day in the drinking water for seven weeks.4Formulations containing betamethasone 12-phosphate and betamethasone acetate have been used in the treatment of severe allergic conditions and a variety of immune-related conditions. 1.Loehle, M., Schwab, M., Kadner, S., et al.Dose-response effects of betamethasone on maturation of the fetal sheep lungAm. J. Obstet. Gynecol.202(2)186.e181-186.e187(2010) 2.Leusink-Muis, A., Ten Broeke, R., Folkerts, G., et al.Betamethasone prevents virus-induced airway inflammation but not airway hyperresponsiveness in guinea pigsClin. Exp. Allergy29(Suppl. 2)82-85(1999) 3.Tsuji, F., Sawa, K., Kato, M., et al.The effects of betamethasone derivatives on endotoxin-induced uveitis in ratExp. Eye Res.64(1)31-36(1997) 4.Aiello, R., Crupi, R., Leo, A., et al.Long-term betamethasone 21-phosphate disodium treatment has distinct effects in CD1 and DBA/2 mice on animal behavior accompanied by opposite effects on neurogenesisBehav. Brain Res.278155-166(2015)

Deoxycorticosterone 21-glucoside is a type of biochemical reagent utilized in glycobiology research. Glycobiology explores the structure, synthesis, biology, and evolution of sugars, encompassing carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. This field is closely linked to basic research, biomedicine, and biotechnology.

Alphadolone 21-β-D-glucuronide (ADG) is a biochemical reagent utilized in glycoscience research. This research explores the structure, synthesis, biology, and evolution of sugars. It encompasses carbohydrate chemistry, glycans' formation and degradation enzymology, protein-glycan interactions, and the role of glycans in biological systems. The field is closely associated with fundamental research, biomedicine, and biotechnology.

Prednisone 21-aldehyde is a reagent used in biochemical reactions.

Beclomethasone 21-propionate is a biochemical reagent utilized in glycobiology research. Glycobiology focuses on the study of the structure, synthesis, biology, and evolution of sugars. This field encompasses carbohydrate chemistry, the enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. It is closely linked to basic research, biomedicine, and biotechnology.

1-Dehydrocorticosterone 21-acetate (1-DHC 21-acetate) is an acetylated derivative of corticosterone, dehydrogenated at the 1 position. It serves as a precursor in the synthesis of 21-hydroxypregna-1,4-diene-3,11,20-trione, which is a metabolite of 1α-hydroxycorticosterone found in rays.

Betamethasone 21-valerate is a corticosteroid ester with anti-inflammatory properties.

Cortisone Acetate is a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate (NSC-49420) diffuses through the cell membrane and binds to nuclear glucocorticoid receptors. The receptor-ligand complex binds to promotor regions of certain genes and initiates RNA transcription. This results in an induction of synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators.

Prednisolone acetate (Omnipred) is the acetate salt form of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.

Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexamethasone also interferes with NF-kB activation and apoptotic pathways. This agent lacks the salt-retaining properties of other related adrenal hormones.

Dexamethasone Phosphate disodium (EGP437. Dex-Phos) is a water-soluble form of the synthetic glucocorticoid dexamethasone.

Cefoperazone sodium salt (CP 52640-2) is a broad-spectrum cephalosporin with a tetrazolyl moiety, utilized for the treatment of Pseudomonas infections.

Hydrocortisone acetate (Cortisol 21-acetate) is the synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties.

Sulfanitran is a sulfonamide antibiotic used in the poultry industry.

Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) is a corticosteroid with anti-inflammatory properties that promotes the polarization of M1 to M2 macrophages by reducing the secretion of pro-inflammatory cytokines, and is utilized in research on keloids and rheumatoid arthritis.

Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent.

Diflucortolone valerate (Diflucortolone 21-valerate) is a corticosteroid esterified with valeric acid. It helps to reduce itching, redness, and swelling.