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MDK5466 is an Flt3 inhibitor that acts by preventing glutamate-induced cell death.

Methyl 2(E),6(Z),9(Z),12(Z),15(Z),18(Z),21(Z)-tetracosaheptaenoate is a lipid utilized in the formulation of lipid nanoparticles (LNP) for drug delivery applications.

2(E),6(Z),9(Z),12(Z),15(Z),18(Z),21(Z)-Tetracosaheptaenoic acid is a lipid that can be utilized in the formulation of lipid nanoparticles (LNP) for drug delivery purposes.

E3 Ligase Ligand 21 (compound 2), a cereblon binder, facilitates the degradation of Ikaros or Aiolos via the ubiquitin proteasome pathway [1].

6α-Methylprednisolone 21-hemisuccinate sodium salt (Asmacortone), a water-soluble ester, is used for allergic, cardiac, and hypoxic emergencies.

Flumethasone 21-acetate is an anti-inflammatory corticosteroid.

Budesonide 21-palmitate is a lipophilic ester prodrug of budesonide, capable of forming liposome formulations. It exhibits anti-inflammatory and anti-allergic activities. Budesonide 21-palmitate enables selective passive targeting and delivery of drugs to tumor tissues, such as lung cancer. It is utilized in research for drug delivery in inflammatory and allergic diseases.

E3LigaseLigand-linker Conjugate 210 is an E3 ubiquitin ligase ligand-linker conjugate (E3ligaseligand-linker conjugate), utilized in the synthesis of PROTACCB1R degrader-1.

E3LigaseLigand-linker Conjugate 216 is a conjugate of the E3 ligase CRBN ligand and a linker. It is utilized in the synthesis of PROTACSARS-CoV-2 RdRp Degrader-1, which is a PROTAC degrader targeting SARS-CoV-2 RdRp.

E3LigaseLigand-linker Conjugate 214 is an E3 ligase ligand-linker complex consisting of a Von Hippel-Lindau (VHL) ligand and a linker. This conjugate can bind with a target protein ligand to form a PROTAC molecule, specifically the PROTACLSD1 Degrader 1.

E3LigaseLigand-linker Conjugate 218 is an E3 ligase ligand-linker conjugate (E3ligaseligand-linker conjugate) employed in the synthesis of the PROTACSTAT6 degrader-2.

E3LigaseLigand-linker Conjugate 213 is a compound that serves as an E3 ubiquitin ligase CRBN ligand-linker conjugate (E3ligaseligand-linker conjugate). This conjugate can be utilized in the synthesis of PSP-0119.

Fce 21258 is used to stimulate the adenylate cyclase of synovial fluid macrophages.

Aldosterone 21-sulfate sodium salt is a cholesterol metabolite discovered in urine.

Prednisone 21-aldehyde is a derivative of the synthetic corticosteroid prednisone that has antiviral activity against influenza virus A-PR8 in embryonated chicken eggs. 22-hydroxy Prednisone is an unstable adduct of prednisone. It has been observed following incubation of prednisone with nornicotine. This product is a mixture of prednisone 21-aldehyde and 22-hydroxy prednisone.

Betamethasone 21-phosphate is a synthetic glucocorticoid.1It prevents increases in macrophage and eosinophil numbers in bronchoalveolar lavage fluid (BALF) and decreases in blood leukocyte numbers in a guinea pig model of parainfluenza-3 viral infection when administered at a dose of 8 mg/kg but does not prevent airway hyperresponsiveness after infection.2Betamethasone 21-phosphate inhibits cell infiltration into the aqueous humor in a rat model of endotoxin-induced uveitis when administered topically or subcutaneously at doses of 0.01-1% or 1 mg/kg, respectively.3It increases maximal lung pressure volume curves in fetal sheep when administered to pregnant ewes at 0.75 gestation at doses of 80 and 170 μg/kg.1Betamethasone 21-phosphate increases body weight, impairs learning and memory, increases anxiolytic behavior, and reduces hippocampal neurogenesis in CD-1 mice but reduces body weight and increases neurogenesis with no effect on anxiety in high-anxiety DBA/2 mice when administered at a dose of approximately 25 mg/kg per day in the drinking water for seven weeks.4Formulations containing betamethasone 12-phosphate and betamethasone acetate have been used in the treatment of severe allergic conditions and a variety of immune-related conditions. 1.Loehle, M., Schwab, M., Kadner, S., et al.Dose-response effects of betamethasone on maturation of the fetal sheep lungAm. J. Obstet. Gynecol.202(2)186.e181-186.e187(2010) 2.Leusink-Muis, A., Ten Broeke, R., Folkerts, G., et al.Betamethasone prevents virus-induced airway inflammation but not airway hyperresponsiveness in guinea pigsClin. Exp. Allergy29(Suppl. 2)82-85(1999) 3.Tsuji, F., Sawa, K., Kato, M., et al.The effects of betamethasone derivatives on endotoxin-induced uveitis in ratExp. Eye Res.64(1)31-36(1997) 4.Aiello, R., Crupi, R., Leo, A., et al.Long-term betamethasone 21-phosphate disodium treatment has distinct effects in CD1 and DBA/2 mice on animal behavior accompanied by opposite effects on neurogenesisBehav. Brain Res.278155-166(2015)

Beclomethasone 21-propionate-d3-1 is the deuterium-labeled form of Beclomethasone 21-propionate. This compound is used as a biochemical reagent in glycobiology research, which examines the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan interactions, and the role of glycans in biological systems, closely connecting with fundamental research, biomedicine, and biotechnology.

Triamcinolone Acetonide 21-Acetate (Standard) is a reference standard of Triamcinolone Acetonide 21-Acetate intended for quantitative analysis, quality control, and related biochemical research applications.

Beclomethasone 21-Monopropionate-3,3,3-D3 (Standard) is a reference standard of Beclomethasone 21-Monopropionate-3,3,3-[D3] intended for quantitative analysis, quality control, and related biochemical research applications.

Deoxycorticosterone 21-glucoside is a type of biochemical reagent utilized in glycobiology research. Glycobiology explores the structure, synthesis, biology, and evolution of sugars, encompassing carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. This field is closely linked to basic research, biomedicine, and biotechnology.

Alphadolone 21-β-D-glucuronide (ADG) is a biochemical reagent utilized in glycoscience research. This research explores the structure, synthesis, biology, and evolution of sugars. It encompasses carbohydrate chemistry, glycans' formation and degradation enzymology, protein-glycan interactions, and the role of glycans in biological systems. The field is closely associated with fundamental research, biomedicine, and biotechnology.

Prednisone 21-aldehyde is a reagent used in biochemical reactions.

Beclomethasone 21-propionate is a biochemical reagent utilized in glycobiology research. Glycobiology focuses on the study of the structure, synthesis, biology, and evolution of sugars. This field encompasses carbohydrate chemistry, the enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. It is closely linked to basic research, biomedicine, and biotechnology.

1-Dehydrocorticosterone 21-acetate (1-DHC 21-acetate) is an acetylated derivative of corticosterone, dehydrogenated at the 1 position. It serves as a precursor in the synthesis of 21-hydroxypregna-1,4-diene-3,11,20-trione, which is a metabolite of 1α-hydroxycorticosterone found in rays.