antioxidant research

Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and a biological system's ability to readily detoxify the reactive intermediates or repair the resulting damage. Disturbances in the normal redox state of cells can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA. In humans, oxidative stress is thought to be involved in the development of atherosclerosis, heart failure, myocardial infarction, cancer, infection etc. Antioxidants are a class of compounds that counteract oxidative stress and reduce oxidative damage. The TargetMol Antioxidant Compound Library is a unique collection of 2010 small molecules with inhibitory effects on oxidative stress and is a useful tool for high-throughput screening and high-content screening in the study of oxidative stress.

A unique collection of 941 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and cancer;

Vitamins are a class of trace organic small molecules essential for maintaining normal life activities in the human body. Most of them cannot be synthesized by the body itself or the synthesis amount is insufficient, and must rely on external intake. Vitamins do not provide energy and do not form cell structure, but as key metabolic regulatory substances, they play irreplaceable physiological functions in the body: for example, B vitamins act as coenzymes to participate in energy and material metabolism; Vitamin C has a powerful antioxidant effect and promotes the synthesis of collagen. Vitamin A maintains visual and immune functions; Vitamin D regulates calcium-phosphorus balance and bone health. Vitamin E protects cell membranes from oxidative damage. Vitamin K plays a core role in blood coagulation and bone metabolism. TargetMol includes 90 kinds of natural vitamins and their derivatives and analogues. All compounds have undergone strict quality control, with high purity and detailed information, and are provided in standardized formats. It is an effective tool resource for promoting research in the field of vitamins and related areas, facilitating the development of new drugs, exploration of disease mechanisms, and innovation of functional products.