upr — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T24928	UPR-IN-17#	UPR inhibitor-17#,UPR IN 17#,UPR inhibitor 17#
	UPR-IN-17# is an effective pan-inhibitor of the unfolded protein response.
T9110	Ceapin-A7		Others
	Ceapin-A7, with an IC50 of 0.59 μM, selectively inhibits ATF6α signaling in response to ER stress. This compound is instrumental in investigating ATF6α's activation mechanism and its function in pathological conditions.		Others
T6854	GSK621		Apoptosis , AMPK , Autophagy
	GSK621 is a specific and potent AMPK activator.		Apoptosis , AMPK , Autophagy
T9349	IXA4		IRE1
	IXA4 is a highly selective, nontoxic activator of IRE1/XBP1s and reduces APP secretion by activating IRE1. IXA4-stimulated IRE1 activation also enhanced pancreatic function.		IRE1
T3496	Buprofezin	NNI 750,Applaud,Buprofezine	Reactive Oxygen Species
	Buprofezin (Applaud) is an insecticide used for control of insect pests such as mealybugs, leafhoppers and whitefly on vegetable crops.		Reactive Oxygen Species
T16724	Razuprotafib	AKB-9778	Phosphatase , Others
	Razuprotafib (AKB-9778) is a protein tyrosine phosphatase ß (HPTPß) inhibitor (IC50: 50 nM). Razuprotafib is effective for the activation of Tie-2 and is protective against acute kidney injury.		Phosphatase , Others
T6540	Ibuprofen Lysine	Neoprofen	COX
	Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.		COX
T40417	Ethylhydrocupreine hydrochloride	Optochin hydrochloride	Antibacterial , Parasite
	Ethylhydrocupreine hydrochloride (Optochin hydrochloride) is a derivative of quinine with antimicrobial activity against Streptococcus pneumoniae.Ethylhydrocupreine hydrochloride has antimalarial activity with an IC50 of...		Antibacterial , Parasite
T12607	Quinupristin		Antibacterial , Antibiotic
	Quinupristin is a member of the macrolide-lincosamide-streptogramin class of antibiotics. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete...		Antibacterial , Antibiotic
T6849	Uprosertib	GSK2141795,GSK795	Akt
	Uprosertib (GSK2141795) (GSK2141795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respectively. Phase 2.		Akt
T21193	Isoflupredone Acetate		Others
	Isoflupredone Acetate is a corticosteroid with the activity of topical anti-inflammatory.		Others
T0324	Isoxsuprine hydrochloride	Duvadilan,Isolait	Adrenergic Receptor , iGluR
	Isoxsuprine hydrochloride (Isolait) is a beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle.		Adrenergic Receptor , iGluR
T21224	(+)-Fluprostenol	Fluprostenol, (+)-,Travoprost acid,AL-5848	Prostaglandin Receptor
	(+)-Fluprostenol (AL-5848), an analogue of prostaglandin F2 alpha, is a prostaglandin F2α receptor PTGFR agonist and decreases the expression of Oviductal glycoprotein 1 (OVGP1).		Prostaglandin Receptor
T27288	Esuprone	LU-43839,LU 43839,LU43839	MAO
	Esuprone (LU-43839) is a novel reversible and highly selective MAO-A inhibitor with anticonvulsant activity for the treatment of depression.		MAO
T7363	Ibuprofen Piconol	U75630	Others
	Ibuprofen Piconol (U75630) is a non-steroidal, anti-inflammatory (NSAID) agent for the topical relief of primary thermal burns and sunburns.Ibuprofen piconol is a Pyridyl ester of ibuprofen.		Others
T41303	Isoflupredone	Delta-Fluorocortisone,Isoflupredona,Isoflupredonum,9-Fluoroprednisolone	Others
	Isoflupredone (Isoflupredonum) is a synthetic corticosteroid that acts in vivo by binding to glucocorticoid and corticosteroid receptors in animals (such as horses) to inhibit inflammatory cells and inhibit the expressio...		Others
TQ0203	Tafluprost	MK2452,AFP-168	Prostaglandin Receptor
	Tafluprost, a prostaglandin analog, is the selective agonist of fluoroprostaglandin (FP) receptor PGF2α.		Prostaglandin Receptor
T17309	(R)-(-)-Ibuprofen	levibuprofen,(R)-Ibuprofen	NF-κB
	(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation. (R)-(-)-Ibuprofen has anti-inflammatory and antinociceptive effects.		NF-κB
T8580	Bupranolol		Adrenergic Receptor
	Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic.		Adrenergic Receptor
T0378	Oxybuprocaine hydrochloride	Risedronic Acid,Oxybuprocaine HCl	Sodium Channel
	Oxybuprocaine hydrochloride (Oxybuprocaine HCl), a local anesthetic, is used especially in otolaryngology and ophthalmology.		Sodium Channel