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Search Results for " ahr "

Targets

98

Compounds

15

Natural Products

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T10269 AHR antagonist 2 Aryl Hydrocarbon Receptor
AHR antagonist 2 is an antagonist of the aryl hydrocarbon receptor. The IC50s for human AHR and mouse AHR are 0.885 and 2.03 nM, respectively.
T39762 AHR antagonist 5 free base Aryl Hydrocarbon Receptor
AHR antagonist 5 free base is an orally active antagonist of AHR with IC50s of ~35-150 nM in human and rodent cell lines.
T5622 BAY-218 AHR antagonist 1 AhR , Aryl Hydrocarbon Receptor
BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line.
T29752 AHR-2666 AHR 2666
AHR-2666 is a skeletal muscle relaxant.
T23681 AHR-15010 AHR 15010
AHR-15010 is a novel anti-arthritic agent.
T29747 AHR-0914 AHR0914,AHR 0914
AHR-0914 is a biochemical.
T29751 AHR-2244 AHR 2244,AHR2244
AHR-2244 is a psychotherapeutic agent.
T16778 Rocastine AHR-11325 Histamine Receptor
Rocastine (AHR-11325) is a selective and potent non-sedating H1 receptor antagonist.
T29746 AHR 376 AHR376,AHR-376
AHR 376 is a biochemical.
T23683 AHR-5333 AHR 5333,AHR5333
AHR-5333 an antiallergy agent.
T23677 AHR-10718 AHR10718,AHR 10718
AHR-10718 has an antiarrhythmic effect.
T23679 AHR-13268D AHR 13268D,AHR13268D
AHR-13268D is a new agent of antiallergic/antihistaminic.
T6424 Bromfenac Sodium AHR 10282B,Bronuck,AHR 10282R COX
Bromfenac Sodium (AHR 10282R) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.
T15302 Fluzinamide AHR-8559 Others
Fluzinamide (AHR-8559) has anticonvulsant effects on ignited amygdala seizures.
T29750 AHR-1900 hydrochloride AHR-1900 HCl
AHR-1900 hydrochloride is a butyrophenone derivative used in the treatment of schizophrenia.
T23682 AHR-16303B oxalate AHR 16303B oxalate
AHR-16303B oxalate is a novel antagonist of 5-HT2 receptors.
T29750L AHR-1900 free base AHR-1900,
AHR-1900 free base is a butyrophenone derivative which may be used in the treatment of schizophrenia.
T29748 AHR-12234
AHR-12234 affects cardiac action potentials.
T29753 AHR-5360 AHR5360
AHR-5360 is a biochemical.
T29749 AHR-16329 AHR16329
AHR-16329 can be used in ocular pharmacology.
T1280 Nepafenac AL 6515,AHR 9434 COX
Nepafenac (AHR 9434) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of nepafenac is as a Cyclooxygenase Inhibitor. The chemical classification of nepafenac is Nonsteroidal Anti-inflammatory Compounds.
T29754 AHR-5859
AHR-5859 is a biochemical.
T29755 AHR-5904
AHR-5904 is a biochemical.
T23678 AHR-11797
AHR-11797 is a novel benzodiazepine antagonist.
T23684 AHR-6293
AHR-6293 is used to distinguishing the effect of anti-platelet aggregating drug properties and the effect of anti-inflammatory properties.
T23676 AHR-10037
AHR-10037 is a nonsteroidal anti-inflammatory drug with analgesic and antipyretic properties as well as a high therapeutic index and low gastric toxicity. AHR-10037 was comparable to indomethacin in suppressing acute (Ev...
T23685 AHR-9294
AHR-9294 is a novel inhibitor of H, K-ATPase. It also antagonizes gastric HCl secretion in vivo.
T23680 AHR-14310C
AHR-14310C is a long-acting and nonsedating H1-antihistamine.
T71590 AHR-5645B fumarate
AHR-5645B fumarate is a substituted benzamide that has been shown to inhibit 3H-spiperone binding to bovine anterior pituitary membranes.
T10271 AHR antagonist 4 Others
AHR antagonist 4 is a potent aryl hydrocarbon receptor (AHR) antagonist(example 293; IC50: 82.2 nM).It has anti-cancer effects.
T10272 AHR antagonist 5 Others
AHR antagonist 5 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist(example 39; IC50 < 0.5 μΜ). It significantly inhibits tumor growth combined with checkpoint inhibitor anti-PD-1.
T71053 AHR-5333 mandelate
AHR-5333 mandelate is an anti-allergy compound which has been shown to protect against antigen-induced anaphylactic collapse and ascaris antigen-induced skin hypersensitivity. AHR-5333 mandelate has also been shown to in...
T1409 Methocarbamol Lumirelax,Metocarbamol,AHR 85,Robaxin Sodium Channel , Carbonic Anhydrase
Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful musc...
T10273 AhR modulator-1 Others
AhR modulator-1 is a selective and orally active aryl hydrocarbon receptor (AhR) modulator. It inhibits metastasis, in part, by inhibiting prostatic VEGF production prior to tumor formation. It also possesses anti-estrog...
T29754L AHR-5859 fumarate
AHR-5859 fumarate is a biochemical.
T20986 AHR agonist 3
AHR agonist 3 is an agent with therapeutic activity.
T23686 AHR-activator-1023 Branching Morphogenesis Modulator 1023,Cpd 1023,Compound 1023,BMM 1023
AHR-activator-1023 is the aryl hydrocarbon receptor activator. It is also a specific FGF2-induced branching morphogenesis modulator.
T17364 AhR Ligand-Linker Conjugates 1 E3 Ligase Ligand-Linker Conjugates 57 Others
AhR Ligand-Linker Conjugates 1, also known as E3 Ligase Ligand-Linker Conjugates 57, is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a SNIPER linker. It is specifically designed to be ...
T21352 Salmefamol AHR-3929,AHR3929,AHR 3929
Salmefamol is a beta-adrenergic agonist. It may also be used as a bronchodilator.
T79436 AHR agonist 4 Aryl Hydrocarbon Receptor
AHR agonist 4 (compound 24e), as an Aryl hydrocarbon receptor (AHR) agonist, modulates the immune equilibrium between Th17/22 and Treg cells. It is a lead compound under investigation for anti-psoriasis drugs and demonst...
T61244 AhR agonist 2
AhR agonist 2 (Compound 12a) is a highly potent agonist of the aryl hydrocarbon receptor (AhR), exhibiting an EC50 value of 0.03 nM. This compound rapidly induces nuclear enrichment of AhR and initiates transcription of ...
T20197 Amfenac sodium AHR5850,AHR 5850
Amfenac is a nonsteroidal anti-inflammatory drug. Amfenac also has acetic acid moiety.
T63389 AHR antagonist 5 hemimaleate
AHR antagonist 5 hemimaleate is a potent antagonist (IC50 < 0.5 μM) of the orally active aryl hydrocarbon receptor (AHR). aHR antagonist 5 hemimaleate in combination with the detection site inhibitor anti-PD-1 exhibited ...
T69174 AHR-5645B free base
AHR-5645B free base is a substituted benzamide which has been shown to inhibit 3H-spiperone binding to bovine anterior pituitary membranes.
T31586 Duoperone fumarate AHR6646,AHR-6646,AHR 6646
Duoperone fumarate is a biochemical.
T30984 Cloroperone hydrochloride AHR-6134,AHR6134,AHR 6134
Cloroperone hydrochloride is a biochemical.
T10963 Dazopride AHR-5531 Others
Dazopride is an antiemetic agent.
T31214 Dazopride fumarate AHR-5531C
Dazopride fumarate is a peristaltic used to enhance gastric emptying and block emesis.
T25661 Lenperone Lenperonum,AHR-2277 [as hydrochloride]
Lenperone is a butyrophenone antipsychotic. Like other major tranquilizers, It has some alpha-adrenergic blocking action and is antiemetic.
T7202 ITE AhR , Aryl Hydrocarbon Receptor
ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.

Compounds

AHR antagonist 2
T10269
Synonym:
Target: Aryl Hydrocarbon Receptor
AHR antagonist 5 free base
T39762
Synonym:
Target: Aryl Hydrocarbon Receptor
BAY-218
T5622
Synonym: AHR antagonist 1
Target: AhR, Aryl Hydrocarbon Receptor
AHR-2666
T29752
Synonym: AHR 2666
Target:
AHR-15010
T23681
Synonym: AHR 15010
Target:
AHR-0914
T29747
Synonym: AHR0914,AHR 0914
Target:
AHR-2244
T29751
Synonym: AHR 2244,AHR2244
Target:
Rocastine
T16778
Synonym: AHR-11325
Target: Histamine Receptor
AHR 376
T29746
Synonym: AHR376,AHR-376
Target:
AHR-5333
T23683
Synonym: AHR 5333,AHR5333
Target:
AHR-10718
T23677
Synonym: AHR10718,AHR 10718
Target:
AHR-13268D
T23679
Synonym: AHR 13268D,AHR13268D
Target:
Bromfenac Sodium
T6424
Synonym: AHR 10282B,Bronuck,AHR 10282R
Target: COX
Fluzinamide
T15302
Synonym: AHR-8559
Target: Others
AHR-1900 hydrochloride
T29750
Synonym: AHR-1900 HCl
Target:
AHR-16303B oxalate
T23682
Synonym: AHR 16303B oxalate
Target:
AHR-1900 free base
T29750L
Synonym: AHR-1900,
Target:
AHR-12234
T29748
Synonym:
Target:
AHR-5360
T29753
Synonym: AHR5360
Target:
AHR-16329
T29749
Synonym: AHR16329
Target:
Nepafenac
T1280
Synonym: AL 6515,AHR 9434
Target: COX
AHR-5859
T29754
Synonym:
Target:
AHR-5904
T29755
Synonym:
Target:
AHR-11797
T23678
Synonym:
Target:
AHR-6293
T23684
Synonym:
Target:
AHR-10037
T23676
Synonym:
Target:
AHR-9294
T23685
Synonym:
Target:
AHR-14310C
T23680
Synonym:
Target:
AHR-5645B fumarate
T71590
Synonym:
Target:
AHR antagonist 4
T10271
Synonym:
Target: Others
AHR antagonist 5
T10272
Synonym:
Target: Others
AHR-5333 mandelate
T71053
Synonym:
Target:
Methocarbamol
T1409
Synonym: Lumirelax,Metocarbamol,AHR 85,Robaxin
Target: Sodium Channel, Carbonic Anhydrase
AhR modulator-1
T10273
Synonym:
Target: Others
AHR-5859 fumarate
T29754L
Synonym:
Target:
AHR agonist 3
T20986
Synonym:
Target:
AHR-activator-1023
T23686
Synonym: Branching Morphogenesis Modulator 1023,Cpd 1023,Compound 1023,BMM 1023
Target:
AhR Ligand-Linker Conjugates 1
T17364
Synonym: E3 Ligase Ligand-Linker Conjugates 57
Target: Others
Salmefamol
T21352
Synonym: AHR-3929,AHR3929,AHR 3929
Target:
AHR agonist 4
T79436
Synonym:
Target: Aryl Hydrocarbon Receptor
AhR agonist 2
T61244
Synonym:
Target:
Amfenac sodium
T20197
Synonym: AHR5850,AHR 5850
Target:
AHR antagonist 5 hemimaleate
T63389
Synonym:
Target:
AHR-5645B free base
T69174
Synonym:
Target:
Duoperone fumarate
T31586
Synonym: AHR6646,AHR-6646,AHR 6646
Target:
Cloroperone hydrochloride
T30984
Synonym: AHR-6134,AHR6134,AHR 6134
Target:
Dazopride
T10963
Synonym: AHR-5531
Target: Others
Dazopride fumarate
T31214
Synonym: AHR-5531C
Target:
Lenperone
T25661
Synonym: Lenperonum,AHR-2277 [as hydrochloride]
Target:
ITE
T7202
Synonym:
Target: AhR, Aryl Hydrocarbon Receptor
1 2
Cat No. Product Name Synonyms Targets
TN1451 Brevifolincarboxylic acid AhR , Aryl Hydrocarbon Receptor , Glucosidase
Brevifolincarboxylic acid is a natural product isolated from Polygonum capitatum, it has inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarboxylic acid is an α-glucosidase inhibitor with an IC50 of 3...
T6795 Carbidopa (S)-(-)-Carbidopa,Lodosyn Decarboxylase , Aryl Hydrocarbon Receptor
Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM). It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA.
T4928 L-Kynurenine (S)-Kynurenine AhR , Aryl Hydrocarbon Receptor , Endogenous Metabolite
L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has ...
T0878 Diosmin Venosmine,Diosmil,Barosmin Aryl Hydrocarbon Receptor , Norepinephrine
Diosmin (Venosmine) is a bioflavonoid that strengthens vascular walls.
TN2883 3',4'-Dimethoxyflavone Others , PARP
3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.
T4939 Indole-3-pyruvic acid 3-(3-Indolyl)-2-oxopropanoic acid Others
Indole-3-pyruvic acid (3-(3-Indolyl)-2-oxopropanoic acid) is a compound involved in the biosynthesis of Indole-3-acetic acid, a plant hormone which plays important roles in regulating growth and responses to environmenta...
T5281 Skatole Scatole,3-Methylindole,3-​Methylindole,3-Methyl-1H-indole,beta-Methylindole AhR , p38 MAPK , Aryl Hydrocarbon Receptor , Endogenous Metabolite , Antibacterial , Autophagy , Antifungal
Skatole (3-Methyl-1H-indole) is produced by intestinal bacteria. Skatole regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.
T2947 Indole-3-carbinol I3C,3-Indolemethanol,Indole-3-Methanol E1/E2/E3 Enzyme , NF-κB , Aryl Hydrocarbon Receptor , Endogenous Metabolite , p53
Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinase activation.
T10938 D-Kynurenine (R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103 GPR , AhR , Endogenous Metabolite
D-Kynurenine (ZINC901103) is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and promotes the conversion of the epithelium to mesenchyme. D-Kynurenine serves as a substrate in the fluor...
T4938 Potassium 1H-indol-3-yl sulfate Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate AhR , Endogenous Metabolite
Potassium 1H-indol-3-yl sulfate (Potassium 3-indoxyl sulfate) is an agonist for the human Aryl Hydrocarbon Receptor (AhR). The Aryl Hydrocarbon Receptor (AhR) has recently emerged as a pathophysiological regulator of imm...
TN1222 26-Deoxyactein 27-Deoxyactein,23-epi-26-Deoxyactein NOS , CDK , NO Synthase
23-epi-26-Deoxyactein (27-Deoxyactein) has anti-inflammatory activity, it inhibits nitric oxide production by reducing iNOS expression without affecting activity of the enzyme. It also has anti-cancer activity, it can in...
T72901 Indolokine A5
Indolokine A5, a catabolite of L-cysteine, is a potent AhR agonist .
T73402 Flavipin
Flavipin is an aryl hydrocarbon receptor (Ahr) agonist that induces the expression of Ahr downstream genes in mouse CD4 + T cells and CD11b + macrophages. Flavipin inhibits the stabilizing function of Arid5a on Il23a 3′U...
TN1543 Cynaropicrin IL Receptor , Others , TNF
Cynaropicrin is a potent activator of the AhR-Nrf2-Nqo1 pathway, and could therefore be applied to prevention of UVB-induced photo aging; it may be a potential anticancer agent against some leukocyte cancer cells such as...
T75433 Norisoboldine hydrochloride
Norisoboldine hydrochloride is an orally active natural aryl hydrocarbon receptor ( AhR ) agonist. Norisoboldine hydrochloride, as a major isoquinoline alkaloid present in Radix Linderae, can be used for the research of ...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-00958 AHR Protein, Human, Recombinant (His) Human E. coli
Thiol protease that plays a key role in programmed cell death by acting as a molecular switch for apoptosis, necroptosis and pyroptosis, and is required to prevent tissue damage during embryonic development and adulthood...
TMPJ-00423 TIM-1/KIM-1/HAVCR1 Protein, Mouse, Recombinant (His) Mouse Human Cells
TIM-1/KIM-1/HAVCR belongs to the immunoglobulin superfamily that cosisits 305 amino acid (aa). It is expressed by stimulated T-cells. TIM-1/KIM-1/HAVCR may play a role in T-helper cell development and the regulation of a...
TargetMol