Tyrosinase

Tyrosinase is a copper-containing enzyme present in plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. It is found inside melanosomes which are synthesised in the skin melanocytes.

Cat. No.	Product name	CAS No.	Purity
T15204	EHT 1610	1425945-60-3	98%
T15204	EHT 1610 is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively. EHT 1610 has an inhibitory effect on leukemia, r...
T25393	Etarotene	87719-32-2	98%
T25393	Etarotene is an ethylsulfonyl derivative of aloe acid with differentiation-inducing and potentially antitumor activity.Etarotene is a collagenase inhibitor and c...
TN4642	Neorauflavane	53734-74-0	98%
TN4642	Neorauflavane shows tyrosinase inhibition, it can inhibit tyrosinase monophenolase activity with an IC50 of 30 nM, it also can efficiently reduce melanin content...
TN4580	Morachalcone A	76472-88-3	98%
TN4580	Morachalcone A displays significant tyrosinase inhibitory activity (IC50, 0.013 uM); it also exerts strong pancreatic lipase inhibition with IC 50 value of 6.2 u...
TC0017	Haplopine	5876-17-5	98%
TC0017	Haplopine shows photo-activated antimicrobial activity against S. aureus. It exhibits potent melanogenesis-inhibitory activities with almost no toxicity to the c...
TN1840	Kurarinol	855746-98-4	98%
TN1840	Kurarinol is a potent inhibitor of sortase A, with an IC50 value of 107.7 ± 6.6 μM. Kurarinol has extremely strong tyrosinase inhibitory activity, exerts varying...
TN2672	2-(2,4-Dihydroxyphenyl)-6-hydroxybenzofuran	67736-22-5	98%
TN2672	2-(2,4-Dihydroxyphenyl)-6-hydroxybenzofuran shows radical scavenging activities. It also shows mushroom tyrosinase inhibitory activity with an IC50 value of 5.2 ...
T37961	P-Tolualdehyde	104-87-0	98%
T37961	p-Tolualdehyde is a RIFM flavor that shows inhibition of mushroom tyrosinase.
TN5117	Taxiphyllin	21401-21-8	98%
TN5117	Taxiphyllin can inhibit tyrosinase activity in vitro significantly and is a potent tyrosinase inhibitor. Taxiphyllin displays mild antibacterial activity against...
TN3540	Broussonin C	76045-49-3	98%
TN3540	Broussonin C and broussin are antifungal compounds. Broussonin C exerts simple reversible slow-binding inhibition against diphenolase.
TN2303	Viscumneoside III	118985-27-6	98%
TN2303	Viscumneoside III, a dihydroflavone O-glycoside, is a potent Tyrosinase inhibitor with an IC50 of 0.5 mM. Viscumneoside III has anti-angina pectoris.
TN3644	Chlorophorin	537-41-7	98%
TN3644	Chlorophorin shows high anti-protozoal activity with an MIC of 0.25 microg/ml. Chlorophorin can strongly inhibit mushroom tyrosinase activity with IC50 values of...
TN2288	Uralenol	139163-15-8	98%
TN2288	Uralenol significantly shows the inhibitory activities against the PTP1B enzyme; it also shows inhibitory activities on mushroom tyrosinase using l-tyrosine as s...
TN2280	Trametenolic acid	24160-36-9	98%
TN2280	Trametenolic acid is a cytotoxic agent.It exhibits a mode of mixed inhibition with a K I of 0.9μM, K IS of 0.5μM, and an IC50 of 7.25μM.Trametenolic acid and Bet...
TN1314	6-Hydroxykaempferol	4324-55-4	98%
TN1314	6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities.
T2S0799	Noroxyhydrastinine	21796-14-5	98%
T2S0799	Noroxyhydrastinine exhibits potent melanogenesis-inhibitory activities, it inhibits melanogenesis, at least in part, by inhibiting the expression of protein leve...
T10664	Calcium 2-oxoglutarate	71686-01-6	98%
T10664	Calcium 2-oxoglutarate is an intermediate in the production of GTP or ATP in the Krebs cycle. It is a reversible inhibitor of tyrosinase (IC50: 15 mM).
TN1832	Kanzonol C	151135-82-9	98%
TN1832	Kanzonol C has antimicrobial activity, it also shows potent PTP1B inhibitory activity (IC50 value of 0.31-0.97uM). Kanzonol C has chemopreventive activity,it sho...
TN1690	Glabrene	60008-03-9	98%
TN1690	Glabrene, Liquiritin apioside, neolicuroside, and 18α²-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likely t...
TN4179	Haginin A	74174-29-1	98%
TN4179	Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt/PKB activ...