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Tyrosinase

Tyrosinase is a copper-containing enzyme present in plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. It is found inside melanosomes which are synthesised in the skin melanocytes.
Cat. No. Product name CAS No. Purity Chemical Structure
T15204 EHT 1610 1425945-60-3 98%
EHT 1610 is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively. EHT 1610 has an inhibitory effect on leukemia, r...
T25393 Etarotene 87719-32-2 98%
Etarotene is an ethylsulfonyl derivative of aloe acid with differentiation-inducing and potentially antitumor activity.Etarotene is a collagenase inhibitor and c...
TN4642 Neorauflavane 53734-74-0 98%
Neorauflavane shows tyrosinase inhibition, it can inhibit tyrosinase monophenolase activity with an IC50 of 30 nM, it also can efficiently reduce melanin content...
TN4580 Morachalcone A 76472-88-3 98%
Morachalcone A displays significant tyrosinase inhibitory activity (IC50, 0.013 uM); it also exerts strong pancreatic lipase inhibition with IC 50 value of 6.2 u...
TC0017 Haplopine 5876-17-5 98%
Haplopine shows photo-activated antimicrobial activity against S. aureus. It exhibits potent melanogenesis-inhibitory activities with almost no toxicity to the c...
TN1840 Kurarinol 855746-98-4 98%
Kurarinol is a potent inhibitor of sortase A, with an IC50 value of 107.7 ± 6.6 μM. Kurarinol has extremely strong tyrosinase inhibitory activity, exerts varying...
TN2672 2-(2,4-Dihydroxyphenyl)-6-hydroxybenzofuran 67736-22-5 98%
2-(2,4-Dihydroxyphenyl)-6-hydroxybenzofuran shows radical scavenging activities. It also shows mushroom tyrosinase inhibitory activity with an IC50 value of 5.2 ...
T37961 P-Tolualdehyde 104-87-0 98%
p-Tolualdehyde is a RIFM flavor that shows inhibition of mushroom tyrosinase.
TN5117 Taxiphyllin 21401-21-8 98%
Taxiphyllin can inhibit tyrosinase activity in vitro significantly and is a potent tyrosinase inhibitor. Taxiphyllin displays mild antibacterial activity against...
TN3540 Broussonin C 76045-49-3 98%
Broussonin C and broussin are antifungal compounds. Broussonin C exerts simple reversible slow-binding inhibition against diphenolase.
TN2303 Viscumneoside III 118985-27-6 98%
Viscumneoside III, a dihydroflavone O-glycoside, is a potent Tyrosinase inhibitor with an IC50 of 0.5 mM. Viscumneoside III has anti-angina pectoris.
TN3644 Chlorophorin 537-41-7 98%
Chlorophorin shows high anti-protozoal activity with an MIC of 0.25 microg/ml. Chlorophorin can strongly inhibit mushroom tyrosinase activity with IC50 values of...
TN2288 Uralenol 139163-15-8 98%
Uralenol significantly shows the inhibitory activities against the PTP1B enzyme; it also shows inhibitory activities on mushroom tyrosinase using l-tyrosine as s...
TN2280 Trametenolic acid 24160-36-9 98%
Trametenolic acid is a cytotoxic agent.It exhibits a mode of mixed inhibition with a K I of 0.9μM, K IS of 0.5μM, and an IC50 of 7.25μM.Trametenolic acid and Bet...
TN1314 6-Hydroxykaempferol 4324-55-4 98%
6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities.
T2S0799 Noroxyhydrastinine 21796-14-5 98%
Noroxyhydrastinine exhibits potent melanogenesis-inhibitory activities, it inhibits melanogenesis, at least in part, by inhibiting the expression of protein leve...
T10664 Calcium 2-oxoglutarate 71686-01-6 98%
Calcium 2-oxoglutarate is an intermediate in the production of GTP or ATP in the Krebs cycle. It is a reversible inhibitor of tyrosinase (IC50: 15 mM).
TN1832 Kanzonol C 151135-82-9 98%
Kanzonol C has antimicrobial activity, it also shows potent PTP1B inhibitory activity (IC50 value of 0.31-0.97uM). Kanzonol C has chemopreventive activity,it sho...
TN1690 Glabrene 60008-03-9 98%
Glabrene, Liquiritin apioside, neolicuroside, and 18α²-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likely t...
TN4179 Haginin A 74174-29-1 98%
Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt/PKB activ...
EHT 1610
T15204
EHT 1610 is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively. EHT 1610 has an inhibitory effect on leukemia, r...
Etarotene
T25393
Etarotene is an ethylsulfonyl derivative of aloe acid with differentiation-inducing and potentially antitumor activity.Etarotene is a collagenase inhibitor and c...
Neorauflavane
TN4642
Neorauflavane shows tyrosinase inhibition, it can inhibit tyrosinase monophenolase activity with an IC50 of 30 nM, it also can efficiently reduce melanin content...
Morachalcone A
TN4580
Morachalcone A displays significant tyrosinase inhibitory activity (IC50, 0.013 uM); it also exerts strong pancreatic lipase inhibition with IC 50 value of 6.2 u...
Haplopine
TC0017
Haplopine shows photo-activated antimicrobial activity against S. aureus. It exhibits potent melanogenesis-inhibitory activities with almost no toxicity to the c...
Kurarinol
TN1840
Kurarinol is a potent inhibitor of sortase A, with an IC50 value of 107.7 ± 6.6 μM. Kurarinol has extremely strong tyrosinase inhibitory activity, exerts varying...
2-(2,4-Dihydroxyphenyl)-6-hydroxybenzofuran
TN2672
2-(2,4-Dihydroxyphenyl)-6-hydroxybenzofuran shows radical scavenging activities. It also shows mushroom tyrosinase inhibitory activity with an IC50 value of 5.2 ...
P-Tolualdehyde
T37961
p-Tolualdehyde is a RIFM flavor that shows inhibition of mushroom tyrosinase.
Taxiphyllin
TN5117
Taxiphyllin can inhibit tyrosinase activity in vitro significantly and is a potent tyrosinase inhibitor. Taxiphyllin displays mild antibacterial activity against...
Broussonin C
TN3540
Broussonin C and broussin are antifungal compounds. Broussonin C exerts simple reversible slow-binding inhibition against diphenolase.
Viscumneoside III
TN2303
Viscumneoside III, a dihydroflavone O-glycoside, is a potent Tyrosinase inhibitor with an IC50 of 0.5 mM. Viscumneoside III has anti-angina pectoris.
Chlorophorin
TN3644
Chlorophorin shows high anti-protozoal activity with an MIC of 0.25 microg/ml. Chlorophorin can strongly inhibit mushroom tyrosinase activity with IC50 values of...
Uralenol
TN2288
Uralenol significantly shows the inhibitory activities against the PTP1B enzyme; it also shows inhibitory activities on mushroom tyrosinase using l-tyrosine as s...
Trametenolic acid
TN2280
Trametenolic acid is a cytotoxic agent.It exhibits a mode of mixed inhibition with a K I of 0.9μM, K IS of 0.5μM, and an IC50 of 7.25μM.Trametenolic acid and Bet...
6-Hydroxykaempferol
TN1314
6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities.
Noroxyhydrastinine
T2S0799
Noroxyhydrastinine exhibits potent melanogenesis-inhibitory activities, it inhibits melanogenesis, at least in part, by inhibiting the expression of protein leve...
Calcium 2-oxoglutarate
T10664
Calcium 2-oxoglutarate is an intermediate in the production of GTP or ATP in the Krebs cycle. It is a reversible inhibitor of tyrosinase (IC50: 15 mM).
Kanzonol C
TN1832
Kanzonol C has antimicrobial activity, it also shows potent PTP1B inhibitory activity (IC50 value of 0.31-0.97uM). Kanzonol C has chemopreventive activity,it sho...
Glabrene
TN1690
Glabrene, Liquiritin apioside, neolicuroside, and 18α²-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likely t...
Haginin A
TN4179
Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt/PKB activ...
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