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ATPase

ATPases ( adenylpyrophosphatase, ATP monophosphatase, triphosphatase, SV40 T-antigen, adenosine 5'-triphosphatase, ATP hydrolase, complex V (mitochondrial electron transport), (Ca2+ + Mg2+)-ATPase, HCO3−-ATPase, adenosine triphosphatase) are a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion[1][2][3][4][5][6] or the inverse reaction. This dephosphorylation reaction releases energy, which the enzyme (in most cases) harnesses to drive other chemical reactions that would not otherwise occur.
Cat. No. Product name CAS No. Purity Chemical Structure
T2093L (S)-PF-03716556 928774-44-1 98%
(S)-PF-03716556 can be used as an acid pump inhibitor for the treatment of disease conditions mediated by acid pump inhibitory activity.
T27371 FR-167356 174185-16-1 98%
FR-167356 is a specific inhibitor of a3 isoform vacuolar type H⁺-ATPase with IC50s of 170 nM, 370 nM and 220 nM for osteoclast plasma membranes, renal brush bord...
T13159 Tiludronate disodium 149845-07-8 98%
Tiludronate disodium is an osteoclast vacuolar H(+)-ATPase inhibitor with antiresorptive and anti-inflammatory properties. Tiludronate disodium can be used in st...
TN3910 Ecdysone 3604-87-3 98%
Ecdysone signaling through Ecdysone receptor isoform B1 is required cell autonomously for the muscle death. A nctional Bombyx Ecdysone receptor binds to EcRE-D a...
TN3042 4-Hydroxycinnamamide 194940-15-3 98%
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
TN3460 Asebogenin 520-42-3 98%
Asebogenin has anti-bacterial activity, it shows inhibitory activity against S. aureus and methicillin-resistant S. aureus (IC50 of 10 and 4.5 micrograms/ml, res...
TN4697 Odoroside H 18810-25-8 98%
Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase.
TN5141 Thevetin B 27127-79-3 98%
Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from Thevetia peruviana.
TN3930 Encecalin 20628-09-5 98%
Encecalin and demethylencecalin are major phytotoxic compounds isolated from Helianthella quinquenervis (Hook) A Gray (Asteraceae), they inhibit photosystem II (...
TN4322 Isopulegol 7786-67-6 98%
Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possibly re...
TN4819 (-)-Praeruptorin A 14017-71-1 98%
(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated rat aorta rings depen...
TN2945 3-Hydroxybakuchiol 178765-54-3 98%
3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondri...
TN1588 Dihydroisotanshinone I 20958-18-3 98%
Dihydroisotanshinone I has protective action against menadione-induced hepatotoxicity, attributed to its antioxidant properties including the free radical scaven...
TN4303 Isokaempferide 1592-70-7 98%
Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by red...
TMA0805 Lupanine 550-90-3 98%
Lupanine has a weak sedative effect on the central nervous system, interaction with specific drugs used for treatment of the CNS and for analgesic activity. Lupa...
TN4160 Goniothalamin 17303-67-2 98%
Goniothalamin induces apoptosis in various cancer cell lines and has gastroprotective activity.
TN5279 Zeorin 22570-53-2 98%
Zeorin shows strong inhibition activity against bacteria and fungi. It markedly exhibits inhibitory activity on histamine release from mast cell induced by DNP24...
TN2306 Wilfordine 37239-51-3 98%
Wilfordine is an insecticidally active alkaloid, Na+-K+-ATPase may be an acting target of wilfordine against some larvae of insect.
TN3557 Cabraleadiol 67253-01-4 98%
Cabraleadiol displays antimycobacterial activity against Mycobacterium tuberculosis, it also is weakly cytotoxic to a breast cancer (BC) cell line. Cabraleadiol ...
TN3737 Cycloartane-3,24,25-triol 57576-29-1 98%
Cycloartane-3,24,25-triol has potential for development as an anti-cancer agent against prostate cancer. It reduces the viability of PC-3 and DU145 cell lines wi...
(S)-PF-03716556
T2093L
(S)-PF-03716556 can be used as an acid pump inhibitor for the treatment of disease conditions mediated by acid pump inhibitory activity.
FR-167356
T27371
FR-167356 is a specific inhibitor of a3 isoform vacuolar type H⁺-ATPase with IC50s of 170 nM, 370 nM and 220 nM for osteoclast plasma membranes, renal brush bord...
Tiludronate disodium
T13159
Tiludronate disodium is an osteoclast vacuolar H(+)-ATPase inhibitor with antiresorptive and anti-inflammatory properties. Tiludronate disodium can be used in st...
Ecdysone
TN3910
Ecdysone signaling through Ecdysone receptor isoform B1 is required cell autonomously for the muscle death. A nctional Bombyx Ecdysone receptor binds to EcRE-D a...
4-Hydroxycinnamamide
TN3042
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
Asebogenin
TN3460
Asebogenin has anti-bacterial activity, it shows inhibitory activity against S. aureus and methicillin-resistant S. aureus (IC50 of 10 and 4.5 micrograms/ml, res...
Odoroside H
TN4697
Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase.
Thevetin B
TN5141
Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from Thevetia peruviana.
Encecalin
TN3930
Encecalin and demethylencecalin are major phytotoxic compounds isolated from Helianthella quinquenervis (Hook) A Gray (Asteraceae), they inhibit photosystem II (...
Isopulegol
TN4322
Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possibly re...
(-)-Praeruptorin A
TN4819
(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated rat aorta rings depen...
3-Hydroxybakuchiol
TN2945
3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondri...
Dihydroisotanshinone I
TN1588
Dihydroisotanshinone I has protective action against menadione-induced hepatotoxicity, attributed to its antioxidant properties including the free radical scaven...
Isokaempferide
TN4303
Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by red...
Lupanine
TMA0805
Lupanine has a weak sedative effect on the central nervous system, interaction with specific drugs used for treatment of the CNS and for analgesic activity. Lupa...
Goniothalamin
TN4160
Goniothalamin induces apoptosis in various cancer cell lines and has gastroprotective activity.
Zeorin
TN5279
Zeorin shows strong inhibition activity against bacteria and fungi. It markedly exhibits inhibitory activity on histamine release from mast cell induced by DNP24...
Wilfordine
TN2306
Wilfordine is an insecticidally active alkaloid, Na+-K+-ATPase may be an acting target of wilfordine against some larvae of insect.
Cabraleadiol
TN3557
Cabraleadiol displays antimycobacterial activity against Mycobacterium tuberculosis, it also is weakly cytotoxic to a breast cancer (BC) cell line. Cabraleadiol ...
Cycloartane-3,24,25-triol
TN3737
Cycloartane-3,24,25-triol has potential for development as an anti-cancer agent against prostate cancer. It reduces the viability of PC-3 and DU145 cell lines wi...
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