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ATPase

ATPases ( adenylpyrophosphatase, ATP monophosphatase, triphosphatase, SV40 T-antigen, adenosine 5'-triphosphatase, ATP hydrolase, complex V (mitochondrial electron transport), (Ca2+ + Mg2+)-ATPase, HCO3−-ATPase, adenosine triphosphatase) are a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion[1][2][3][4][5][6] or the inverse reaction. This dephosphorylation reaction releases energy, which the enzyme (in most cases) harnesses to drive other chemical reactions that would not otherwise occur.
Cat. No. Product name CAS No. Purity Chemical Structure
TN1588 Dihydroisotanshinone I 20958-18-3 98%
Dihydroisotanshinone I has protective action against menadione-induced hepatotoxicity, attributed to its antioxidant properties including the free radical scaven...
TN4819 (-)-Praeruptorin A 14017-71-1 98%
(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated rat aorta rings depen...
TN3737 Cycloartane-3,24,25-triol 57576-29-1 98%
Cycloartane-3,24,25-triol has potential for development as an anti-cancer agent against prostate cancer. It reduces the viability of PC-3 and DU145 cell lines wi...
T13159 Tiludronate disodium 149845-07-8 98%
Tiludronate disodium is an osteoclast vacuolar H(+)-ATPase inhibitor with antiresorptive and anti-inflammatory properties. Tiludronate disodium can be used in st...
TN3042 4-Hydroxycinnamamide 194940-15-3 98%
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
TN3075 5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone 98187-98-5 98%
5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone (ED 50 =4.5 ug/ml ) shows cytotoxicity against L1210 cell and has inhibiting effects on ATPase from the cell.
TN4303 Isokaempferide 1592-70-7 98%
Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by red...
TN1711 Gossypetin 489-35-0 98%
Gossypetin has anti-mutagenic, anti-atherosclerotic, antioxidant, as well as cytoprotective and antimicrobial effects, it inhibits bone resorption through down-r...
TMA0805 Lupanine 550-90-3 98%
Lupanine has a weak sedative effect on the central nervous system, interaction with specific drugs used for treatment of the CNS and for analgesic activity. Lupa...
TN3627 Chalepensin 13164-03-9 98%
Chalepensin behaves as an energy transfer inhibitor at low concentration, it inhibits multiple P450s and that epoxidation activity is crucial for the potential d...
TN5060 Stauntosaponin A 1417887-91-2 98%
Stauntosaponin A and stauntosaponin B show moderate inhibitory activities against Na+/K+-ATPase with IC50 values of 21 and 29 uM, respectively.
TN3557 Cabraleadiol 67253-01-4 98%
Cabraleadiol displays antimycobacterial activity against Mycobacterium tuberculosis, it also is weakly cytotoxic to a breast cancer (BC) cell line. Cabraleadiol ...
T16865 SCH28080 76081-98-6 98%
SCH28080 inhibits gastric H+/K+-ATPase by K+-competitive binding (IC50: 20 nM in rabbit microsomal membranes).
TN1912 Marinobufogenin 470-42-8 98%
Marinobufagenin, a cardiotonic steroid, its increased concentrations are important in the cardiac disease and oxidant stress state seen with renal failure.
TN3930 Encecalin 20628-09-5 98%
Encecalin and demethylencecalin are major phytotoxic compounds isolated from Helianthella quinquenervis (Hook) A Gray (Asteraceae), they inhibit photosystem II (...
TN2945 3-Hydroxybakuchiol 178765-54-3 98%
3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondri...
TN4322 Isopulegol 7786-67-6 98%
Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possibly re...
TN4418 Lasiodiplodin 32885-81-7 98%
Lasiodiplodin may have potential anti-inflammatory activity, it shows moderate suppression effects on induced NO production. Lasiodiplodin inhibits electron tran...
TN3460 Asebogenin 520-42-3 98%
Asebogenin has anti-bacterial activity, it shows inhibitory activity against S. aureus and methicillin-resistant S. aureus (IC50 of 10 and 4.5 micrograms/ml, res...
T2093 PF 03716556 928774-43-0 98%
PF 3716556, an effective and specific P-CAB (potassium-competitive acid blocker), is utilized for the treatment of gastroesophageal reflux disease.
Dihydroisotanshinone I
TN1588
Dihydroisotanshinone I has protective action against menadione-induced hepatotoxicity, attributed to its antioxidant properties including the free radical scaven...
(-)-Praeruptorin A
TN4819
(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated rat aorta rings depen...
Cycloartane-3,24,25-triol
TN3737
Cycloartane-3,24,25-triol has potential for development as an anti-cancer agent against prostate cancer. It reduces the viability of PC-3 and DU145 cell lines wi...
Tiludronate disodium
T13159
Tiludronate disodium is an osteoclast vacuolar H(+)-ATPase inhibitor with antiresorptive and anti-inflammatory properties. Tiludronate disodium can be used in st...
4-Hydroxycinnamamide
TN3042
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone
TN3075
5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone (ED 50 =4.5 ug/ml ) shows cytotoxicity against L1210 cell and has inhibiting effects on ATPase from the cell.
Isokaempferide
TN4303
Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by red...
Gossypetin
TN1711
Gossypetin has anti-mutagenic, anti-atherosclerotic, antioxidant, as well as cytoprotective and antimicrobial effects, it inhibits bone resorption through down-r...
Lupanine
TMA0805
Lupanine has a weak sedative effect on the central nervous system, interaction with specific drugs used for treatment of the CNS and for analgesic activity. Lupa...
Chalepensin
TN3627
Chalepensin behaves as an energy transfer inhibitor at low concentration, it inhibits multiple P450s and that epoxidation activity is crucial for the potential d...
Stauntosaponin A
TN5060
Stauntosaponin A and stauntosaponin B show moderate inhibitory activities against Na+/K+-ATPase with IC50 values of 21 and 29 uM, respectively.
Cabraleadiol
TN3557
Cabraleadiol displays antimycobacterial activity against Mycobacterium tuberculosis, it also is weakly cytotoxic to a breast cancer (BC) cell line. Cabraleadiol ...
SCH28080
T16865
SCH28080 inhibits gastric H+/K+-ATPase by K+-competitive binding (IC50: 20 nM in rabbit microsomal membranes).
Marinobufogenin
TN1912
Marinobufagenin, a cardiotonic steroid, its increased concentrations are important in the cardiac disease and oxidant stress state seen with renal failure.
Encecalin
TN3930
Encecalin and demethylencecalin are major phytotoxic compounds isolated from Helianthella quinquenervis (Hook) A Gray (Asteraceae), they inhibit photosystem II (...
3-Hydroxybakuchiol
TN2945
3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondri...
Isopulegol
TN4322
Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possibly re...
Lasiodiplodin
TN4418
Lasiodiplodin may have potential anti-inflammatory activity, it shows moderate suppression effects on induced NO production. Lasiodiplodin inhibits electron tran...
Asebogenin
TN3460
Asebogenin has anti-bacterial activity, it shows inhibitory activity against S. aureus and methicillin-resistant S. aureus (IC50 of 10 and 4.5 micrograms/ml, res...
PF 03716556
T2093
PF 3716556, an effective and specific P-CAB (potassium-competitive acid blocker), is utilized for the treatment of gastroesophageal reflux disease.
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