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(4)
By Target- c-Met/HGFR
- Apoptosis(2)
- ALK(1)
- Autophagy(1)
- Discoidin Domain Receptor (DDR)(1)
- E1/E2/E3 Enzyme(1)
- EGFR(1)
- FLT(1)
- NOD(1)
- Others(20)
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Results for "
proto-oncogene
" in TargetMol Product Catalog- Inhibitors & Agonists16
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- Antibody Products43
Amivantamab
JNJ-61186372, JNJ61186372, JNJ 61186372
T771102171511-58-1
Amivantamab (JNJ-61186372) is a humanized antibody that recognizes epidermal growth factor receptor (EGFR) and MET proto-oncogene (MET), with anticancer and anti-tumor activities, preventing ligand binding to EGFR and MET and receptor dimerization that inhibits downstream signal transduction. Amivantamab can induce Fc-dependent endocytosis of macrophages and antibody-dependent cytotoxicity of natural killer cells, and can be used to study metastatic non-small cell lung cancer.
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