head — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T82221	Head activator neuropeptide
	Head activator neuropeptide, a mitogen for neuronal or neuroendocrine mammalian cell lines, induces mitosis by signaling through GPR37 binding [1].
T7459	Abametapir	HA-44,BRN 0123183	MMP , Others , Parasite
	Abametapir (BRN 0123183), a metalloproteinase inhibitor, is able to target metalloproteinases critical to egg hatching and louse development.		MMP , Others , Parasite
T26889	Borofalan(10B)	L-4-Boronophenylalanine	Others
	Borofalan(10B) (L-4-Boronophenylalanine) echibits antineoplastic effects. Borofalan can be used in studies on recurrent or locally advanced head and neck cancer.		Others
T7727	Se-Methylselenocysteine	Se MSC,SeMCys,MSeC,Se-MSC,SeMSC	BCL , IAP , Caspase
	Se-Methylselenocysteine (Se-MSC) is a potent chemopreventive agent in many test systems and has been shown to inhibit tumor promotion and induce apoptosis.		BCL , IAP , Caspase
T17035	Temoporfin		Others
	Temoporfin used in photodynamic therapy for the treatment of squamous cell carcinoma of the head and neck.		Others
TP1114L	Leucokinin VIII acetate	Leucokinin 8	Others
	Leucokinin VIII acetate (Leucokinin 8) is an diuretic octapeptide isolated form head extracts of the cockroach.		Others
T25284	DAC-2-25	DAC 225,DAC-225,DAC 2 25	Others
	DAC-2-25 is a Hydra head regeneration modulator. It acts by inducing a homeotic transformation in Hydra.		Others
T5330	Fluralaner	AH252723,A1443	GABA Receptor , Parasite
	Fluralaner (A1443) is an isoxazoline ectoparasiticide. It potently and selectively inhibits binding of the GABA receptor channel blocker EBOB to housefly head membranes (IC50: 455 pM).		GABA Receptor , Parasite
T10337	Antimicrobial Compound 1		Antibacterial
	Antimicrobial Compound 1 is an alkyl pyridinium compound with Tail 12C, Head 4-carboxyl. Antimicrobial Compound 1 exhibits antimicrobial activities against B. subtilis and E. coli.		Antibacterial
T0790	Carbaryl	1-naphthyl methylcarbamate,Sevin	AChR
	Carbaryl (1-naphthyl methylcarbamate) is a carbamate insecticide and parasiticide. It is a potent anticholinesterase agent belonging to the carbamate group of reversible cholinesterase inhibitors. It has a particularly l...		AChR
T76696	Onvatilimab	JNJ-61610588	Others
	Onvatilimab (JNJ-61610588) is a human IgG1 κ-anti-Vista (T-cell-activated V-domain Ig inhibitor) monoclonal antibody. Onvatilimab has antitumor activity and can be used to treat advanced head and neck cancers.		Others
T2618	LGK974	LGK 974,LGK-974,NVP-LGK974,WNT974	Porcupine
	LGK974 (NVP-LGK974) is an effective and selective PORCN inhibitor and inhibits Wnt signaling (IC50: 0.4 nM) in TM3 cells. It has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cel...		Porcupine
T3674	Hydroxysafflor yellow A	HSYA,Safflomin A	TGF-beta/Smad
	Hydroxysafflor yellow A (Safflomin A) inhibited adipogenesis by increasing HSL promoter activities. Hydroxysafflor yellow A can effectively protect the liver from long-term alcohol injury by enhancing antioxidant capacit...		TGF-beta/Smad
T77423	Lirilumab	ONO-4483,IPH2102	Virus Protease
	Lirilumab (IPH2102) is an antibody against the lethal immunoglobulin-like receptor antibody KIR2D with antitumor activity that enhances the anti-HPV + cervical cancer activity of natural killer cells through VAV1-depende...		Virus Protease
T3229	Cytochalasin D		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
	Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head dec...		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
TN2539	1beta-Hydroxyalantolactone		IL Receptor , TNF
	1beta-Hydroxyalantolactone is a small molecular compound isolated from the flower head of the medicinal plant giant British flower, which can inhibit the expression of TNF-α, IL-17 and IFN-γ in cells, promote the secreti...		IL Receptor , TNF
T76890	Petosemtamab	MCLA 158	EGFR
	Petosemtamab (MCLA 158) is a highly potent monoclonal antibody against EGFR (Kd: 0.22 nM) and LGR5 (Kd: 0.86 nM). Petosemtamab promotes EGFR signaling disruption and receptor breakdown in LGR5+ cancer cells. Petosemtamab...		EGFR
T0729	Benzyl benzoate	Ascabiol,Novoscabin,Scabitox,Benzoic acid benzyl ester	Parasite
	Benzyl benzoate (Benzoic acid benzyl ester) is one of the older preparations used for the therapy of scabies. Scabies is a skin infection caused by the Sarcoptes scabiei. Its symptoms are red spots, severe itching (parti...		Parasite
T4889	2,6-Diaminoheptanedioic acid		Others , Endogenous Metabolite
	Diaminopimelic acid or DAPA is a lysine-like amino acid derivative that is a key component of the bacterial cell wall. DAPA is incorporated or integrated into peptidoglycan of gram negative bacteria and is the attachment...		Others , Endogenous Metabolite
T25683	Leucomyosuppressin	p-Glu-asp-val-asp-his-val-phe-leu-arg-phe-NH2
	Leucomyosuppressin, isolated from head extracts of the cockroach Leucophaea maderae, inhibits evoked transmitter release at the mealworm neuromuscular junction.