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Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
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TargetMol
Cytokines and Growth Factors •   Cytokines •   Growth Factors Receptor Proteins •   Fc Receptors •   Cytokines and Growth Factor Receptors
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Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

Search Result

Search Results for " defects "

Targets

PERK

32

Compounds

3

Natural Products

465

Recombinant Proteins

2

Libraries

Cat No. Product Name Synonyms Targets
T9149 2BAct 2B-Act,2B Act PERK
2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response
T25829 Mopidamol RA233,RA 233,RA-233,Rapenton,OLX 102 PDE
Mopidamol (RA 233) is a phosphodiesterase inhibitor, a dipyridamole derivative, with anticancer activity that prevents retinal vascular defects in experimental diabetes.
T35074 VRT-325 CFcor 325,VRT-534,CFcor325,VRT 325,VRT325,CF-106951,CFcor-325 Others
VRT-325 can repair folding defects by promoting dimerization of the two NBDs or by promoting folding of the TMD.VRT-325 accelerates the healing rate of CF cell monolayers.
T14847 B I09 Others , IRE1
B I09, an IRE-1 RNase inhibitor with an IC50 of 1230 nM, inhibits splicing of XBP1 mRNA in human WaC3 cells and expression of xbp-1 in LPS-stimulated B cells. B I09 can be used to simulate the defects of XBP-1 in CLL cel...
T0183 Pramiracetam CI-879 Others
Pramiracetam (CI-879), derived from piracetam, is a more effective nootropic drug . According to reports, Pramiracetam improved cognitive defects related with traumatic brain wounds. Pramiracetam was also potent in the t...
T29114 VRT-532 CFpot-532,CFpot-532) CFTR
VRT-532 (CFpot-532) is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects. Arylsulfatase B (ARSB), which is necessary to reduce the accumulation of sulphate glyc...
T4497L Amifampridine phosphate BRN0110232,3,6-DAP,SC10,BRN 0110232,BRN-0110232,NSC 521760
Amifampridine is mainly used to treat many rare muscle diseases. In the United States, aminopyridine is being studied for the treatment of Lambert-Eaton myasmus syndrome (LEMS). Amifampridine is also used to treat many c...
T27562 Hydroxyellipticine-1a
Hydroxyellipticine-1a, a selective r(CGG)exp probe, improves pre-mRNA splicing defects, inhibits formation of nuclear inclusions and RANT in a FXTAS cellular mode.l
T32125 Hyperphyllin HP
Hyperphyllin specifically mimics the branch defects of AMP1, including plastid reduction and expansion and proliferation of the branch meristem.
T22860 Imeglimin Others
Imeglimin is the first in a new tetrahydrotriazine-containing class of oral antidiabetic agents. It has been shown to act on the liver, muscle, and pancreatic β-cells to uniquely target the key defects of type 2 diabetes...
T69440 Sephin1 Hydrochloride
Sephin1 hydrochloride is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A), which prolongs the benefit of eIF2α phosphorylation, thereby protecting cells from proteostatic defects.
T40908 KLD-12
KLD-12, a 12-residue self-assembling peptide, displays properties that promote chondrogenic differentiation of bone marrow stromal cells (BMSCs). Moreover, KLD-12 hydrogel can effectively fill full-thickness osteochondra...
T73107 RAD51-IN-4
RAD51-IN-4 is a potent RAD51 inhibitor, targeting a eukaryote gene critical for studies on conditions associated with mitochondrial defects.
T76649 Osteostatin (human)
Osteostatin (human), a fragment derived from parathyroid hormone-related protein (PTHrP) 107-139, effectively promotes bone repair in animal models with bone defects and inhibits bone erosion in cases of inflammatory art...
T25496 Hexaglutamate folate Pteglu6
Hexaglutamate folate is a naturally occurring form of folic acid. The bioavailability of dietary folate may be limited by the need for the glutamate moieties to be deconjugated before absorption. Folate deficiency in hum...
T73702 Mecasermin
Mecasermin (Human IGF-I; FK 780), a recombinant form of human insulin-like growth factor I (IGF-I), holds promise for investigating growth failure attributed to growth hormone (GH) insensitivity, which may be due to defe...
T82056 IP2
IP2, an immunomodulatory agent, enhances PTP (Pioneer Translation Product)-derived antigen presentation in cancer cells without exhibiting cytotoxicity. Additionally, IP2 has been shown to induce tumor growth defects in ...
T37666 Trihydroxycholestanoic Acid Trihydroxycoprostanic Acid
Trihydroxycholestanoic acid is an intermediate in the biosynthesis of cholic acid .1 Elevated plasma levels of trihydroxycholestanoic acid have been found in patients with Zellweger syndrome, a neurological disorder char...
T32706 Levomefolate calcium pentahydrate
Levomefolate calcium pentahydrate is the calcium salt of 5-methyltetrahydrofolic acid, a biologically active form of folic acid that functions, in conjunction with Vitamin B12. Levomefolate is included in formulations of...
T38189 2-hydroxy Lignoceric Acid
2-hydroxy Lignoceric acid is an α-hydroxy very long chain fatty acid that is normally present in the mammalian nervous system. In the brain, 2-hydroxy lignoceric acid is derived from lignoceric acid and further converted...
T28685 SB236057 SB-236057,SB 236057
SB236057 is a potent and selective inverse agonist for the 5-HT receptor, acting especially at 5-HT autoreceptors on nerve terminals. It produces a rapid increase in 5-HT levels in the brain. SB236057 also acts as a pote...
T35729 Nemadipine-A
Nemadipine A is an L-type calcium channel blocker that induces morphological and growth defects in wild-type C. elegans and those with hypoexpression of egl-19, which encodes the only L-type calcium channel α1-subunit in...
T35594 Cuspin-1
The Survival of Motor Neurons (SMN) protein participates in RNA splicing. Decreases in SMN, typically a consequence of defects in the smn1 gene, result in the death of motor neurons and lead to the neurodegenerative dise...
T36801 Binucleine 2
Binucleine 2 is an isoform-specific and ATP-competitive inhibitor of Drosophila Aurora B kinase (Ki = 0.36 μM), a kinase involved in cell division. It is specific for Drosophila Aurora B kinase, inhibiting it in a dose-d...
T78241 Asfotase alfa ENB-0040
Asfotase alfa (ENB-0040), a bone-targeted genetically engineered glycoprotein, enhances survival, bone mineralization, and growth while preventing mineralization defects in the feet, rib cage, lower limbs, and jaws of Ak...
T68480 4SC-207
4SC-207 is a novel microtubule inhibitor , which shows strong anti-proliferative activity in a large panel of tumor cell lines with an average GI50 of 11 nM. In particular, 4SC-207 is active in multi-drug resistant cell ...
T81592 Osteostatin PTHrP (107–111)
Osteostatin, derived from parathyroid hormone-related protein (PTHrP) 107-111, has demonstrated properties conducive to bone repair in animal models presenting with bone defects and exhibits efficacy in mitigating bone e...
T37193 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside
4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside is a fluorogenic substrate for β-hexosaminidases. Upon enzymatic cleavage by β-hexosaminidases, 4-methylumbelliferone (4-μU) is released and its fluorescence c...
T78024 Selcopintide acetate Cpne7-DP acetate
Selcopintide acetate (Cpne7-DP), a synthetic peptide, mirrors the 344-353 amino acid sequence of the hCPNE7 protein. It effectively mimics CPNE7's in vitro activity, enhancing the expression of odontoblast markers like D...
T38187 6-Aminophenanthridine
6-Aminophenanthridine is an antiprion agent. It inhibits prion formation in yeast- and mammalian-based screening assays when used alone and, to a greater extent, when used in combination with the α2-adrenergic receptor a...
T21881 Fluconazole hydrate
Fluconazole (hydrate) is a triazole antifungal agent used for the oral treatment and prevention of both superficial and systemic fungal infections, including but not limited to balanitis, various Candida infections, Cryp...
T37441 KMN-80
The prostaglandin E receptor 4 (EP4) is one of four G protein-coupled receptors that mediate the actions of prostaglandin E2 . Binding of PGE2 to the EP4 receptor causes an increase in intracellular cyclic AMP, which pla...

Compounds

2BAct
T9149
Synonym: 2B-Act,2B Act
Target: PERK
Mopidamol
T25829
Synonym: RA233,RA 233,RA-233,Rapenton,OLX 102
Target: PDE
VRT-325
T35074
Synonym: CFcor 325,VRT-534,CFcor325,VRT 325,VRT325,CF-106951,CFcor-325
Target: Others
B I09
T14847
Synonym:
Target: Others, IRE1
Pramiracetam
T0183
Synonym: CI-879
Target: Others
VRT-532
T29114
Synonym: CFpot-532,CFpot-532)
Target: CFTR
Amifampridine phosphate
T4497L
Synonym: BRN0110232,3,6-DAP,SC10,BRN 0110232,BRN-0110232,NSC 521760
Target:
Hydroxyellipticine-1a
T27562
Synonym:
Target:
Hyperphyllin
T32125
Synonym: HP
Target:
Imeglimin
T22860
Synonym:
Target: Others
Sephin1 Hydrochloride
T69440
Synonym:
Target:
KLD-12
T40908
Synonym:
Target:
RAD51-IN-4
T73107
Synonym:
Target:
Osteostatin (human)
T76649
Synonym:
Target:
Hexaglutamate folate
T25496
Synonym: Pteglu6
Target:
Mecasermin
T73702
Synonym:
Target:
IP2
T82056
Synonym:
Target:
Trihydroxycholestanoic Acid
T37666
Synonym: Trihydroxycoprostanic Acid
Target:
Levomefolate calcium pentahydrate
T32706
Synonym:
Target:
2-hydroxy Lignoceric Acid
T38189
Synonym:
Target:
SB236057
T28685
Synonym: SB-236057,SB 236057
Target:
Nemadipine-A
T35729
Synonym:
Target:
Cuspin-1
T35594
Synonym:
Target:
Binucleine 2
T36801
Synonym:
Target:
Asfotase alfa
T78241
Synonym: ENB-0040
Target:
4SC-207
T68480
Synonym:
Target:
Osteostatin
T81592
Synonym: PTHrP (107–111)
Target:
4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside
T37193
Synonym:
Target:
Selcopintide acetate
T78024
Synonym: Cpne7-DP acetate
Target:
6-Aminophenanthridine
T38187
Synonym:
Target:
Fluconazole hydrate
T21881
Synonym:
Target:
KMN-80
T37441
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T0062 Folic acid Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,Folacin DNA/RNA Synthesis , Endogenous Metabolite
Folic acid (Vitamin B9)(Vitamin M; Vitamin B9) is indispensable for the production and maintenance of new cells, for DNA/RNA synthesis.
T4877 L-Homocystine Endogenous Metabolite
Homocystine is the double-bonded form of homocysteine, but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Increasing evidence supports a role for an ele...
T83582 (±)-Pantothenic acid (±)-Vitamin B5,(±)-Pantothenate
(±)-Pantothenic acid ((±)-Pantothenate), a B-vitamin, is essential for coenzyme A (CoA) biosynthesis in mammalian cells and exhibits protective activity against valproic acid (VPA)-induced neural tube defects (NTD) in CD...

Natural Products

Folic acid
T0062
Synonym: Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,Folacin
Target: DNA/RNA Synthesis, Endogenous Metabolite
L-Homocystine
T4877
Synonym:
Target: Endogenous Metabolite
(±)-Pantothenic acid
T83582
Synonym: (±)-Vitamin B5,(±)-Pantothenate
Target:

Recombinant Proteins

Species：
Human (287)
Mouse (85)
Rat (35)
Cynomolgus (25)
Canine (15)
Rhesus (10)
Ferret (2)
Human (2)
Mouse,Rat (1)
Rabbit (1)
Expression System：
HEK293 (274)
E. coli (90)
Baculovirus-Insect Cells (56)
Human Cells (37)
CHO (6)
Yeast (2)
Tag：
His (200)
hFc (80)
C-6His (34)
Tag Free (31)
His,GST (24)
None (18)
His,hFc (12)
GST (10)
His,AVI (10)
N-6His (8)
Cat No. Product Name Species Expression System
TMPY-04142 RANK/TNFRSF11A Protein, Human, Recombinant (hFc) Human HEK293
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i...
TMPY-05423 C-MPL Protein, Rat, Recombinant (hFc) Rat HEK293
CD11, also known as c-MPL, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs. It is expressed at a low level in a large number o...
TMPK-00942 DLK1 Protein, Mouse, Recombinant (His) Mouse HEK293
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neu...
TMPY-02215 Coagulation factor IX/F9 Protein, Human, Recombinant (His) Human HEK293
Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX / F9 contains two EGF-like domains, on...
TMPY-02279 Nucleoside phosphorylase/PNP Protein, Human, Recombinant (His) Human E. coli
Purine nucleoside phosphorylase (PNP) is a purine-metabolizing enzyme that catalyzes the reversible phosphorolysis of 6-oxypurine (deoxy)nucleosides to their respective bases and (deoxy)ribose-1-phosphate. It is a key en...
TMPY-01650 CD131 Protein, Human, Recombinant (His) Human HEK293
Colony stimulating factor 2 receptor, beta, low-affinity (CSF2RB) also known as CD131 antigen (CD131), cytokine receptor common subunit beta, GM-CSF/IL-3/IL-5 receptor common beta-chain, interleukin 3 receptor/granulocyt...
TMPJ-00258 TGF beta 2 Protein, Human, Recombinant Human Human Cells
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. T...
TMPY-02185 Coagulation factor XIII B/F13B Protein, Human, Recombinant (His) Human HEK293
Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ...
TMPY-00654 ACVR2B Protein, Human, Recombinant (hFc) Human HEK293
ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ...
TMPY-01735 Carbonic Anhydrase 2 Protein, Human, Recombinant (His) Human E. coli
The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bi...
TMPY-01475 Jagged 1 Protein, Human, Recombinant (His) Human HEK293
Protein Jagged 1, also known as JAG1, JAGL1, and CD339, is a single-pass type I membrane protein that contains 1 DSL domain and 15 EGF-like domains. JAG1/Jagged 1 is widely expressed in adult and fetal tissues. The expre...
TMPY-01281 ACVR2B Protein, Mouse, Recombinant (His) Mouse HEK293
ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ...
TMPJ-00261 TGF beta 2 Protein, Mouse/Rat, Recombinant Mouse,Rat Human Cells
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofaci...
TMPY-04483 IRAK4 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4...
TMPY-02956 Apolipoprotein L/APOL1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
APOL1, also known as apolipoprotein L1, is a minor apoprotein component of HDL (High-density lipoprotein) or 'good cholesterol' which is synthesized in the liver and also in many other tissues, including pancreas, kidney...
TMPY-02801 PHGDH Protein, Human, Recombinant (His) Human E. coli
PHGDH is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family. This new family consists of D-isomer-stereospecific enzymes. The conserved residues in this family appear to be the residues involved in the ...
TMPY-02767 TPP1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Tripeptidyl-peptidase 1 (TPP1 / CLN2) is a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activit...
TMPY-02899 Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (His) Mouse HEK293
Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and...
TMPY-03203 CD40 Protein, Rat, Recombinant (His) Rat HEK293
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory...
TMPY-01181 CD40 Protein, Human, Recombinant (His) Human HEK293
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory...
TMPY-00665 Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His) Human HEK293
Aminopeptidase N (ANPEP or APN), also known as CD13, is a cell-surface metalloprotease located in the small-intestinal and renal microvillar membrane, as well as other plasma membranes. It belongs to the peptidase M1 fam...
TMPY-05957 CD40 Protein, Mouse, Recombinant (His) Mouse HEK293
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory...
TMPY-05364 CD8 alpha Protein, Human, Recombinant (hFc) Human HEK293
T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been imp...
TMPY-05134 CD8 alpha Protein, Mouse, Recombinant (His), Biotinylated Mouse HEK293
T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been imp...
TMPY-04261 CD64 Protein, Human, Recombinant (His) Human HEK293
High affinity immunoglobulin gamma Fc receptor I, also known as FCGR1 and CD64, is an integral membraneglycoprotein and a member of the immunoglobulin superfamily. CD64 is a high affinity receptor for the Fc region of...
TMPY-02585 Acid sphingomyelinase/SMPD1 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Sphingomyelin phosphodiesterase 1 (SMPD1) , also known as ASM ( acid sphingomyelinase ), is a member of the acid sphingomyelinase family of enzymes. Three isoforms have been identified, isoform 1 is 631 amino acids (aa) ...
TMPY-02707 PAH Protein, Human, Recombinant (415 Asn/Asp, His) Human Baculovirus-Insect Cells
PAH (phenylalanine hydroxylase), also known as PH, belongs to the biopterin-dependent aromatic amino acid hydroxylase family. It contains 1 ACT domain, N-terminal region of PAH is thought to contain allosteric binding si...
TMPY-01884 MMP-8 Protein, Human, Recombinant Human HEK293
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ...
TMPY-00381 PSMA Protein, Human, Recombinant (His) Human HEK293
Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote...
TMPY-05350 CD8 alpha Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been imp...
TMPY-01205 CD64 Protein, Mouse, Recombinant (His) Mouse HEK293
High affinity immunoglobulin gamma Fc receptor I, also known as FCGR1 and CD64, is an integral membraneglycoprotein and a member of the immunoglobulin superfamily. CD64 is a high affinity receptor for the Fc region of...
TMPY-03345 Sonic Hedgehog Protein, Mouse, Recombinant (His) Mouse HEK293
Sonic HedgeHog, also known as sonic hedgehog protein, belongs to the hedgehog family. It cannot be detected in adult tissues while can be found in fetal intestine, liver, lung, and kidney. Sonic HedgeHog is a protein tha...
TMPY-02078 HtrA2/Omi Protein, Human, Recombinant (His) Human E. coli
Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the ...
TMPY-01371 IL-17RA Protein, Human, Recombinant (His) Human HEK293
Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secret...
TMPY-02019 CD59 Protein, Human, Recombinant (His) Human HEK293
CD59 glycoprotein, also known as 2 kDa homologous restriction factor, HRF2, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membran...
TMPY-05435 ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) Human HEK293
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis...
TMPY-00423 FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) Human HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-01727 GLA/alpha-Galactosidase A Protein, Human, Recombinant (His) Human HEK293
Alpha-galactosidase A, also known as Alpha-D-galactoside galactohydrolase, Alpha-D-galactosidase A, Melibiase and GLA, is a member of the glycosyl hydrolase 27 family. GLA is used as a long-term enzyme replacement therap...
TMPY-00882 Mer Protein, Human, Recombinant (His & hFc) Human HEK293
Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-02335 OSMR Protein, Mouse, Recombinant (His) Mouse HEK293
Oncostatin-M specific receptor subunit beta also known as the oncostatin M receptor (OSMR) and Interleukin-31 receptor subunit beta (IL-31RB), is one of the receptor proteins for oncostatin M. OSMR is a member of the typ...
TMPY-01061 FGF-10 Protein, Human, Recombinant Human E. coli
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes...
TMPY-01305 OSMR Protein, Human, Recombinant (His) Human HEK293
Oncostatin-M specific receptor subunit beta also known as the oncostatin M receptor (OSMR) and Interleukin-31 receptor subunit beta (IL-31RB), is one of the receptor proteins for oncostatin M. OSMR is a member of the typ...
TMPY-04878 IGF1/IGF-I Protein, Mouse, Recombinant Mouse Yeast
IGF I, also known as Mechano Growth Factor, somatomedin-C, IGF-I, and IGF1, is a secreted protein that belongs to the insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and I...
TMPY-01085 VLDLR Protein, Human, Recombinant (His) Human HEK293
The very low density lipoprotein receptor, known as VLDLR, is a single-pass type 1 integral membrance protein and a member of the LDL receptor family. This receptor family includes LDL receptor, LRP, megalin, VLDLR and A...
TMPY-00972 FGFR2 Protein, Human, Recombinant (His & hFc) Human HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-04051 C-Kit Protein, Human, Recombinant (hFc) Human HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-01011 FGFR1 Protein, Human, Recombinant (His) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-01703 TREM-2 Protein, Mouse, Recombinant (His) Mouse HEK293
Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPY-01250 IL-11R alpha/IL-11RA Protein, Mouse, Recombinant (His) Mouse HEK293
Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, includi...
TMPY-06036 FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
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RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
TMPY-04142
Species: Human
Expression System: HEK293
C-MPL Protein, Rat, Recombinant (hFc)
TMPY-05423
Species: Rat
Expression System: HEK293
DLK1 Protein, Mouse, Recombinant (His)
TMPK-00942
Species: Mouse
Expression System: HEK293
Coagulation factor IX/F9 Protein, Human, Recombinant (His)
TMPY-02215
Species: Human
Expression System: HEK293
Nucleoside phosphorylase/PNP Protein, Human, Recombinant (His)
TMPY-02279
Species: Human
Expression System: E. coli
CD131 Protein, Human, Recombinant (His)
TMPY-01650
Species: Human
Expression System: HEK293
TGF beta 2 Protein, Human, Recombinant
TMPJ-00258
Species: Human
Expression System: Human Cells
Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)
TMPY-02185
Species: Human
Expression System: HEK293
ACVR2B Protein, Human, Recombinant (hFc)
TMPY-00654
Species: Human
Expression System: HEK293
Carbonic Anhydrase 2 Protein, Human, Recombinant (His)
TMPY-01735
Species: Human
Expression System: E. coli
Jagged 1 Protein, Human, Recombinant (His)
TMPY-01475
Species: Human
Expression System: HEK293
ACVR2B Protein, Mouse, Recombinant (His)
TMPY-01281
Species: Mouse
Expression System: HEK293
TGF beta 2 Protein, Mouse/Rat, Recombinant
TMPJ-00261
Species: Mouse,Rat
Expression System: Human Cells
IRAK4 Protein, Human, Recombinant (His)
TMPY-04483
Species: Human
Expression System: Baculovirus-Insect Cells
Apolipoprotein L/APOL1 Protein, Human, Recombinant (His)
TMPY-02956
Species: Human
Expression System: Baculovirus-Insect Cells
PHGDH Protein, Human, Recombinant (His)
TMPY-02801
Species: Human
Expression System: E. coli
TPP1 Protein, Human, Recombinant (His)
TMPY-02767
Species: Human
Expression System: Baculovirus-Insect Cells
Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (His)
TMPY-02899
Species: Mouse
Expression System: HEK293
CD40 Protein, Rat, Recombinant (His)
TMPY-03203
Species: Rat
Expression System: HEK293
CD40 Protein, Human, Recombinant (His)
TMPY-01181
Species: Human
Expression System: HEK293
Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His)
TMPY-00665
Species: Human
Expression System: HEK293
CD40 Protein, Mouse, Recombinant (His)
TMPY-05957
Species: Mouse
Expression System: HEK293
CD8 alpha Protein, Human, Recombinant (hFc)
TMPY-05364
Species: Human
Expression System: HEK293
CD8 alpha Protein, Mouse, Recombinant (His), Biotinylated
TMPY-05134
Species: Mouse
Expression System: HEK293
CD64 Protein, Human, Recombinant (His)
TMPY-04261
Species: Human
Expression System: HEK293
Acid sphingomyelinase/SMPD1 Protein, Mouse, Recombinant (His)
TMPY-02585
Species: Mouse
Expression System: Baculovirus-Insect Cells
PAH Protein, Human, Recombinant (415 Asn/Asp, His)
TMPY-02707
Species: Human
Expression System: Baculovirus-Insect Cells
MMP-8 Protein, Human, Recombinant
TMPY-01884
Species: Human
Expression System: HEK293
PSMA Protein, Human, Recombinant (His)
TMPY-00381
Species: Human
Expression System: HEK293
CD8 alpha Protein, Cynomolgus, Recombinant (hFc)
TMPY-05350
Species: Cynomolgus
Expression System: HEK293
CD64 Protein, Mouse, Recombinant (His)
TMPY-01205
Species: Mouse
Expression System: HEK293
Sonic Hedgehog Protein, Mouse, Recombinant (His)
TMPY-03345
Species: Mouse
Expression System: HEK293
HtrA2/Omi Protein, Human, Recombinant (His)
TMPY-02078
Species: Human
Expression System: E. coli
IL-17RA Protein, Human, Recombinant (His)
TMPY-01371
Species: Human
Expression System: HEK293
CD59 Protein, Human, Recombinant (His)
TMPY-02019
Species: Human
Expression System: HEK293
ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)
TMPY-05435
Species: Human
Expression System: HEK293
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)
TMPY-00423
Species: Human
Expression System: HEK293
GLA/alpha-Galactosidase A Protein, Human, Recombinant (His)
TMPY-01727
Species: Human
Expression System: HEK293
Mer Protein, Human, Recombinant (His & hFc)
TMPY-00882
Species: Human
Expression System: HEK293
OSMR Protein, Mouse, Recombinant (His)
TMPY-02335
Species: Mouse
Expression System: HEK293
FGF-10 Protein, Human, Recombinant
TMPY-01061
Species: Human
Expression System: E. coli
OSMR Protein, Human, Recombinant (His)
TMPY-01305
Species: Human
Expression System: HEK293
IGF1/IGF-I Protein, Mouse, Recombinant
TMPY-04878
Species: Mouse
Expression System: Yeast
VLDLR Protein, Human, Recombinant (His)
TMPY-01085
Species: Human
Expression System: HEK293
FGFR2 Protein, Human, Recombinant (His & hFc)
TMPY-00972
Species: Human
Expression System: HEK293
c-Kit Protein, Human, Recombinant (hFc)
TMPY-04051
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (His)
TMPY-01011
Species: Human
Expression System: HEK293
TREM-2 Protein, Mouse, Recombinant (His)
TMPY-01703
Species: Mouse
Expression System: HEK293
IL-11R alpha/IL-11RA Protein, Mouse, Recombinant (His)
TMPY-01250
Species: Mouse
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
TMPY-06036
Species: Human
Expression System: HEK293
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Cat No. Product Name
L3200 Autophagy Compound Library

1248 compounds
A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
L5400 Anti-Cardiovascular Disease Compound Library

1428 compounds
A unique collection of 1428 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS);

Libraries

Autophagy Compound Library
L3200
Compounds: 1248
Anti-Cardiovascular Disease Compound Library
L5400
Compounds: 1428
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