vegfr-2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T37078	VEGFR-2-IN-6		VEGFR
	VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].		VEGFR
T10123	VEGFR-2-IN-9	KDR-in-4	VEGFR
	VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer.		VEGFR
T9979	VEGFR-2-IN-29		VEGFR
	VEGFR-2-IN-29 is a VEGFR2 inhibitor.		VEGFR
T2056	VEGFR-2-IN-5	2, 4-Pyrimidinediamine with linker,UNC0064-12,2,4-Pyrimidinediamine with linker	VEGFR
	VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.		VEGFR
T40581	TIE-2/VEGFR-2 kinase-IN-2
	TIE-2/VEGFR-2 kinase-IN-2 is a powerful inhibitor of both VEGFR2 and Tie-2 kinases, displaying noteworthy pIC 50 values of 8.61 and 8.56, respectively. This compound acts as an anti-angiogenic agent, making it highly rel...
T79860	TIE-2/VEGFR-2 kinase-IN-5		VEGFR , Tie-2
	TIE-2/VEGFR-2 kinase-IN-5 is a potent TIE-2 and VEGFR-2 tyrosine kinase receptor inhibitor with anti-angiogenic activity and is commonly used in biomedical research related to angiogenesis.		VEGFR , Tie-2
T8817	TIE-2/VEGFR-2 kinase-IN-1
	TIE-2/VEGFR-2 kinase-IN-1 is used for the synthesis of TIE-2 and/or VEGFR-2 inhibitors that can be used for the study of diseases associated with inappropriate angiogenesis [1].
T9724	VEGFR2-IN-2		Others
	VEGFR2-IN-2 has anti-inflammatory and analgesic activities.		Others
TP1474	LXW7		Integrin
	LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (ECs) targeting ligand. LXW7 is a disulfide cyclic octa-pepti...		Integrin
T8213	Isolinderalactone		NOS , STAT
	Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.		NOS , STAT
T22432	SU5208	3-[(Thien-2-yl)methylene]-2-indolinone	VEGFR
	SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) is a compound with bioactivity.SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2).		VEGFR
T22349	JNJ-38158471	CS-2660	VEGFR , c-RET , c-Kit
	JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor with IC50 of 40 nM, inhibits closely related tyrosine kinases such as Ret and Kit with IC50 of 180 nM and 500 nM.		VEGFR , c-RET , c-Kit
T22431	SU5204	3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one	EGFR , VEGFR , HER
	SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and HER2)		EGFR , VEGFR , HER
T5349	SCR-1481B1	c-Met inhibitor 2	VEGFR , c-Met/HGFR
	SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitor		VEGFR , c-Met/HGFR
T64060	VEGFR-2-IN-21
	VEGFR-2-IN-21 is a potent inhibitor of VEGFR-2 (IC50: 0.10 μM) and exhibits anticancer effects.
T62071	VEGFR-2-IN-16
	VEGFR-2-IN-16 (Compound 15b) is a potent inhibitor of VEGFR-2 (IC50: 86.36 nM) that exhibits antitumour effects.
T62901	VEGFR-2-IN-27
	VEGFR-2-IN-27 (compound 7a) is a potent inhibitor of VEGFR-2 (IC50: 14.8 nM) and can be used in anticancer studies.
T61561	VEGFR-2-IN-18
	VEGFR-2-IN-18 (Compound 15d) is a high-potency inhibitor of VEGFR-2, with an IC 50 value of 60 nM. This compound effectively initiates cell apoptosis and demonstrates significant antitumor properties [1].
T78819	VEGFR-2-IN-33		VEGFR
	VEGFR-2-IN-33 (Compound 4d), a potent VEGFR inhibitor with an IC50 value of 61.04 nM, demonstrates significant inhibition of HepG2 cell proliferation, achieving an IC50 of 4.31 nM. This compound is utilized for hepatocel...		VEGFR
T63822	VEGFR-2-IN-22
	VEGFR-2-IN-22 (Compound 25) is an inhibitor of VEGFR-2 and β-tubulin polymerization with an IC50=19.82 nM for VEGFR-2. VEGFR-2-IN-22 is capable of inducing apoptosis.