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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16366 | NVR 3-778 | HBV | |
NVR 3-778 is a first-in-Class and oral bioavailable HBV CAM belonging to the SBA class It has anti-HBV activity. | |||
T11465 | Lenacapavir | GS-6207 | Others , HIV Protease |
Lenacapavir (GS-6207) is a potent capsid-targeting inhibitor of HIV replication. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells. | |||
T16500 | PF-3450074 | PF-74 | HIV Protease |
PF-3450074 (PF-74) acts at an early stage of HIV-1 infection inhibits viral replication by directly competing with the binding of CPSF6 (nuclear host factors cleavage and polyadenylation specific factor 6) and NUP153 (nu... | |||
T9054 | RO6889678 | HBV | |
RO6889678 is HBV inhibitor with a complex ADME profile. | |||
T6439 | Cetylpyridinium Chloride | Cetamium,Pristacin,Hexadecylpyridinium Chloride | Others , HBV , Antibacterial |
Cetylpyridinium Chloride (Hexadecylpyridinium Chloride) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic. | |||
T4536 | Pleconaril | VP 63843,Win 63843,Picovir | Virus Protease , Antiviral |
Pleconaril (VP 63843) is a capsid inhibitor used previously to treat enterovirus infections. Pleconaril is effective in inhibiting replication (IC50: 50 nM). | |||
T3345 | Hederasaponin B | Eleutheroside M,Hederacoside B | Others , Virus Protease |
Hederasaponin B (Hederacoside B) has antiviral activity, via inhibiting the viral VP2 protein expression and blocking viral capsid protein synthesis. | |||
T4475 | JNJ-632 | HBV | |
JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator. | |||
TQ0017 | AB-423 | HBV | |
AB-423 is an inhibitor of HBV capsid assembly, and potently inhibits HBV replication (EC50/EC90: 0.08-0.27 μM/0.33-1.32 μM in cells). | |||
T27221 | DVR-01 | 3-(azepan-1-ylsulfonyl)-N-benzyl-4-chlorobenzamide | HBV |
DVR-01 is an HBV capsid inhibitor and can be used in studies about the treatment of Hepatitis B virus (HBV) infection and related conditions. | |||
T20000 | I-XW-053 | HIV Protease | |
I-XW-053 is a capsid targeted HIV-1 replication inhibitor. | |||
T4492 | Pocapavir | SCH-48973,V-073 | Virus Protease , Antiviral |
Pocapavir (SCH-48973) is an investigational enterovirus (EV) capsid inhibitor. | |||
T1750 | Pirodavir | R77975 | Virus Protease , Antiviral |
Pirodavir (R77975) (R 77975), the prototype of broad-spectrum anti-picornavirus compounds, is a potent human rhinovirus (HRV) capsid-binding inhibitor. | |||
T5782 | Bevirimat | YK FH312,MPC-4326,PA-457 | HIV Protease |
Bevirimat (PA-457) is a first-in-class inhibitor of HIV-1 maturation, blocking the cleavage of the Gag capsid (CA) precursor, CA-SPI, to mature CA protein during virion maturation. | |||
TP1739L | HEX3 acetate(688805-40-5 free base) | Others | |
HEX3 acetate is a fragment of the adenoviral hexon. Hexon is the major capsid protein of adenovirion and is comprised of three identical polypeptide chains. | |||
T11409 | GLP-26 | HBV | |
GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools. GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM... | |||
T28860 | ST-148 | ST148 | |
ST-148 is a potent inhibitor for Dengue virus capsid. ST-148-enhanced capsid protein self-interaction perturbs assembly and disassembly of DV nucleocapsids, probably by inducing structural rigidity. | |||
T26756 | BCM-599 | BCM 599 | |
BCM-599 is a HBV capsid assembly inhibitor. BCM-599 showed IC50 of 0.88 μM and CC50 of 144 μM in HepG2.2.15 cells. | |||
T71799 | CAP-1 | ||
CAP-1 is an inhibitor of HIV-1 capsid formation. | |||
T13284 | Vapendavir diphosphate | BTA798 diphosphate | Others |
Vapendavir diphosphate is a potent enteroviral capsid binder (CB) and has a potent antiviral activity for enterovirus 71 (EV71) replication (EC50: 0.5-1.4 μM in different EV71 strains). |