Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • GTPase
    (19)
  • Ras
    (13)
  • Dynamin
    (6)
  • Rho
    (5)
  • CDK
    (4)
  • Apoptosis
    (3)
  • Autophagy
    (2)
  • Endogenous Metabolite
    (2)
  • AChR
    (1)
  • Others
    (51)
Filter
Search Result
Results for "

gtpase

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    88
    TargetMol | Inhibitors_Agonists
  • Peptide Products
    7
    TargetMol | Peptide_Products
  • Natural Products
    4
    TargetMol | Natural_Products
  • Recombinant Protein
    96
    TargetMol | Recombinant_Protein
  • Antibody Products
    5
    TargetMol | Antibody_Products
CID-4785700
CID4785700
T71740852935-07-0In house
CID-4785700 is a potent pan-GTPase inhibitor that inhibits Rab7 and inhibits the fungal histone acetyltransferase Rtt109 that binds to Asf1 and Vps75, and can be used in the study of lupus.
  • Inquiry Price
6-8 weeks
Size
QTY
RAS GTPase inhibitor 1
T126922252242-32-1In house
RAS GTPase inhibitor 1 is a RAS GTPase inhibitor with potential antitumor activity.
  • Inquiry Price
7-10 days
Size
QTY
Rac GTPase fragment
TP2287
Rac GTPase fragment is a peptide with the sequence H2N-Val-Phe-Asp-Glu-Ala-Ile-Arg-Ala-Val-OH, MW= 1019.15. Rac is a subfamily of the Rho family of GTPases, small signaling G proteins (more specifically a GTPase).
  • Inquiry Price
Size
QTY
CCG-50014
CCG 50014
T6434883050-24-6
CCG-50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.
  • Inquiry Price
Size
QTY
Anti-inflammatory agent 49
T83057851471-44-8In house
Anti-inflammatory agent 49 is a potent inhibitor of Drp1-Fis1 interaction, inhibits GTPase, and can be used in the study of diseases caused by mitochondrial dysfunction.
  • Inquiry Price
8-10 weeks
Size
QTY
Tyrphostin 8
4-Hydroxybenzylidenemalononitrile
T349733785-90-8
Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) is a potent GTPase inhibitor that inhibits EGFR kinase with an IC50 of 560 μM.Tyrphostin 8 inhibits protein serine threonine calmodulin phosphatases (IC50=21 μM), enhances transferrin receptor-mediated transcytosis in Caco-2 cells, and increases the hypoglycemic effect of oral insulin-transferrin. hypoglycemic effect.
  • Inquiry Price
7-10 days
Size
QTY
Exo-1
Methyl 3-(4-fluorobenzoyl)-6-methyl-2-pyridinecarboxylate
T9200461681-88-9
Exo-1 (Methyl 3-(4-fluorobenzoyl)-6-methyl-2-pyridinecarboxylate) is a synthetic compound that has been shown to affect the metabolism of various nutrients, as well as the regulation of various hormones. It has also been shown to have anti-inflammatory and anti-tumor effects.
  • Inquiry Price
Size
QTY
QS11
QS 11
T4022944328-88-5
QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also reduces in vitro migration of metastatic human breast cancer cells.
  • Inquiry Price
4-6 weeks
Size
QTY
TargetMol | Inhibitor Sale
RBC8
T6634361185-42-4
RBC8 is a specific GTPases RalA RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.
  • Inquiry Price
Size
QTY
Dynamin inhibitory peptide Acetate
Dynamin inhibitory peptide Acetate(251634-21-6 Free base)
T21798L
Dynamin inhibitory peptide Acetate is a peptide with the sequence Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro that inhibit the GTPase dynamin.
  • Inquiry Price
Size
QTY
BQU57
T22671637739-82-2
BQU57 selectively inhibits Ral over Ras or Rho and suppresses xenograft tumor growth.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
IMM-01
T25529218795-74-5
IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin filaments, and their organization with microfilaments to establish and maintain cell polarity during migration and asymmetric division. GTP-bound Rho activates mDia family members by disrupting the interaction between the DID and DAD autoregulatory domains, which releases the FH2 domain to modulate actin and microtubule dynamics[1].
  • Inquiry Price
Size
QTY
Compound C108
T3838715533-09-2
Compound C108 is an inhibitor of GTPase-activating protein SH3 domain-binding protein 2 (G3BP2). Compound C108 can be used in studies about breast tumors and esophageal squamous cell carcinoma.
  • Inquiry Price
6-8 weeks
Size
QTY
Gancaonin I
TN4098126716-36-7
Gancaonin I exhibits anti-BsFtsZ GTPase activities; it also shows significant inhibitory activity against B. subtilis, with a MIC value of 5 uM.
  • Inquiry Price
Size
QTY
CCG 203769
4-butyl-2-ethyl-1,2,4-thiadiazolidine-3,5-dione, RGS4 inhibitor 11b, Thiadiazolidinone (TDZD) deriv. 6
T10705410074-60-1
CCG 203769 (Thiadiazolidinone (TDZD) deriv. 6) is a selective inhibitor of RGS4 with an IC50 of 17 nM for the RGS4-Gαo protein-protein interaction.
  • Inquiry Price
6-8weeks
Size
QTY
CCG-63802
T14897620112-78-9
CCG-63802 is a reversible inhibitor of the regulator of G-protein signaling (RGS) protein and has the greatest potency at RGS4.
  • Inquiry Price
6-8 weeks
Size
QTY
CCG-63808
T14898620113-73-7
CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins, dose-dependently inhibiting the TR-FRET signal between RGS4-AF488 and Tb-Gαo with an IC50 value of 1.9 μM.
  • Inquiry Price
6-8 weeks
Size
QTY
ML-097
T21970743456-83-9
ML-097 (CID-2160985) is a universal activator of Ras-related GTPases.
  • Inquiry Price
Size
QTY
RBC10
RBC 10, RBC-10
T24706362503-73-9
RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines.
  • Inquiry Price
6-8 weeks
Size
QTY
NAV-2729
T5142419547-11-8
NAV-2729 inhibits six ArfGEFs (human ARNO, EFA6, BIG1, and BRAG2 and Legionella and Rickettsia RalF), the strongest effects being against BRAG2, Arf1 and Arf6.
  • Inquiry Price
Size
QTY
Morelloflavone
Fukugetin
TN551516851-21-1
Morelloflavone is a biflavonoid derived from Garcinia cambogia with anticancer property that inhibits tumor angiogenesis by targeting Rho GTPases and the extracellular signal-regulated kinase (ERK) signaling pathway. Fukugetin inhibits the cellular proliferation of a variety of cancer cell lines, such as Caspase-9, TNF -α, ER-α, , HER-2.
  • Inquiry Price
Size
QTY
Mdivi-1
Mitochondrial division inhibitor 1
T1907338967-87-6
Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM). Mdivi-1 inhibits mitochondrial autophagy.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Hot
Dynamin IN-2
T643691345853-49-7In house
Dynamin IN-2 (compound 43) is a Wiskostatin analogue. Dynamin IN-2 is a potent dynamin inhibitor (dynamin I GTPase, IC50= 1.0 μM). Dynamin IN-2 blocks clathrin mediated endocytosis (CME) (IC50= 9.5 μM).
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
Tetradecyltrimethylammonium bromide
MitMAB, Cetrimide, tetradecyl trimethyl ammonium bromide
T229811119-97-7
Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.
  • Inquiry Price
Size
QTY